Endogenous mechanisms of neuroprotection: Role of zinc, copper, and carnosine

Brain Research

Volumn 852, Issue 1, 2000, Pages 56-61

  Horning, Michelle S ^a   Blakemore, Laura J ^a   Trombley, Paul Q ^a  

^a FLORIDA STATE UNIVERSITY   (United States)

Author keywords

Alzheimer's disease; Neurodegenerative disease; Neurotoxicity; Olfactory bulb; Rat; Tissue culture

Indexed keywords

CARNOSINE; COPPER; EDETIC ACID; ZINC;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; CELL ACTIVITY; CELL DEATH; CEREBROVASCULAR ACCIDENT; CONTROLLED STUDY; GLIA CELL; NERVE CELL; NERVE EXCITABILITY; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; OLFACTORY SYSTEM; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RAT; SEIZURE; VISUAL SYSTEM;

ANIMALS; ANIMALS, NEWBORN; BRAIN; CARNOSINE; CELL SURVIVAL; CELLS, CULTURED; CHELATING AGENTS; COPPER; EDETIC ACID; FETUS; NEURONS; NEUROPROTECTIVE AGENTS; NEUROTOXINS; RATS; RATS, SPRAGUE-DAWLEY; ZINC;

EID: 0033959828     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(99)02215-5     Document Type: Article

References (45)

1. Agarwal K., Sharma A., Talukder G. Effects of copper on mammalian cell components. Chem. Biol. Interact. 69:1989;1-16.
2. 2+ from brain tissue during activity. Nature. 308:1984;734-736.
3. Atwood C.S., Moir R.D., Huang X., Scarpa R.C., Bacarra N.M., Romano D.M., Hartshorn M.A., Tanzi R.E., Bush A.I. Dramatic aggregation of Alzheimer abeta by Cu(II) is induced by conditions representing physiological acidosis. J. Biol. Chem. 273:1998;12817-12826.
4. Berg J.M., Shi Y. The galvanization of biology: a growing appreciation for the roles of zinc. Science. 271:1996;1081-1085.
5. Biffo S., Grillo M., Margolis F.L. Cellular localization of carnosine-like and anserine-like immunoreactivities in rodent and avian central nervous system. Neuroscience. 35:1990;637-651.
6. Boldyrev A.A., Stvolinsky S.L., Tyulina O.V., Koshelev V.B., Hori N., Carpenter D.O. Biochemical and physiological evidence that carnosine is an endogenous neuroprotector against free radicals. Cell Mol. Neurobiol. 17:1997;259-271.
7. Brown C.E., Antholine W.E. Chelation chemistry of carnosine. Evidence that mixed complexes may occur in vivo. Journal of Physical Chemistry. 83:1979;3314-3319.
8. Bush A.I., Pettingell W.H., Multhaup G., d Paradis M., Vonsattel J.P., Gusella J.F., Beyreuther K., Masters C.L., Tanzi R.E. Rapid induction of Alzheimer A beta amyloid formation by zinc [see comments]. Science. 265:1994;1464-1467.
9. Choi D.W., Yokoyama M., Koh J. Zinc neurotoxicity in cortical cell culture. Neuroscience. 24:1988;67-79.
10. Christine C.W., Choi D.W. Effect of zinc on NMDA receptor-mediated channel currents in cortical neurons. J. Neurosci. 10:1990;108-116.
11. Chvapil M., Ryan J.N., Zukoski C.F. The effect of zinc and other metals on the stability of lysosomes. Proc. Soc. Exp. Biol. Med. 140:1972;642-646.
12. Constantinidis J., Tissot R. Role of glutamate and zinc in the hippocampal lesions of Pick's disease. Adv. Biochem. Psychopharmacol. 27:1981;413-422.
13. Csermely P., Szamel M., Resch K., Somogyi J. Zinc can increase the activity of protein kinase C and contributes to its binding to plasma membranes in T lymphocytes. J. Biol. Chem. 263:1988;6487-6490.
14. Cuajungco M.P., Lees G.J. Zinc metabolism in the brain: relevance to human neurodegenerative disorders. Neurobiol. Dis. 4:1997;137-169.
15. DiDonato M., Sarkar B. Copper transport and its alterations in Menkes and Wilson diseases. Biochim. Biophys. Acta. 1360:1997;3-16.
16. 2+ in rat brain regions. Can. J. Biochem. 51:1973;87-92.
17. Ferriero D., Margolis F.L. Denervation in the primary olfactory pathway of mice: II. Effects on carnosine and other amine compounds. Brain Research. 94:1975;75-86.
18. Forsythe I.D., Westbrook G.L., Mayer M.L. Modulation of excitatory synaptic transmission by glycine and zinc in cultures of mouse hippocampal neurons. J. Neurosci. 8:1988;3733-3741.
19. Frederickson C.J. Neurobiology of zinc and zinc-containing neurons. Int. Rev. Neurobiol. 31:1989;145-238.
20. Frederickson C.J., Hernandez M.D., McGinty J.F. Translocation of zinc may contribute to seizure-induced death of neurons. Brain Res. 480:1989;317-321.
21. Gulya K., Kovacs G.L., Kasa P. Partial depletion of endogenous zinc level by (D-Pen2, D- Pen5)enkephalin in the rat brain. Life Sci. 48:1991;PL57-62.
22. Hartter D.E., Barnea A. Evidence for release of copper in the brain: depolarization-induced release of newly taken-up 67copper. Synapse. 2:1988;412-415.
23. Kardos J., Kovacs I., Hajos F., Kalman M., Simonyi M. Nerve endings from rat brain tissue release copper upon depolarization. A possible role in regulating neuronal excitability. Neurosci Lett. 103:1989;139-144.
24. Koh J.Y., Suh S.W., Gwag B.J., He Y.Y., Hsu C.Y., Choi D.W. The role of zinc in selective neuronal death after transient global cerebral ischemia. Science. 272:1996;1013-1016.
25. Kohen R., Yamamoto Y., Cundy K.C., Ames B.N. Antioxidant activity of carnosine, homocarnosine, and anserine present in muscle and brain. Proc. Natl. Acad. Sci. U. S. A. 85:1988;3175-3179.
26. Kress Y., Gaskin F., Brosnan C.F., Levine S. Effects of zinc on the cytoskeletal proteins in the central nervous system of the rat. Brain Res. 220:1981;139-149.
27. Lovell M.A., Robertson J.D., Teesdale W.J., Campbell J.L., Markesbery W.R. Copper, iron and zinc in Alzheimer's disease senile plaques. J. Neurol. Sci. 158:1998;47-52.
28. Mayer M.L., Vyklicky L. Jr. The action of zinc on synaptic transmission and neuronal excitability in cultures of mouse hippocampus. J. Physiol. (London). 415:1989;351-365.
29. Multhaup G. Amyloid precursor protein, copper and Alzheimer's disease. Biomed. Pharmacother. 51:1997;105-111.
30. Munch G., Mayer S., Michaelis J., Hipkiss A.R., Riederer P., Muller R., Neumann A., Schinzel R., Cunningham A.M. Influence of advanced glycation end-products and AGE-inhibitors on nucleation-dependent polymerization of beta-amyloid peptide. Biochim. Biophys. Acta. 1360:1997;17-29.
31. Pognetto M.S., Cantino D., Fasolo A. Carnosine-like immunoreactivity is associated with synaptic vesicles in photoreceptors of the frog retina. Brain Res. 578:1992;261-268.
32. Preston J.E., Hipkiss A.R., Himsworth D.T., Romero I.A., Abbott J.N. Toxic effects of beta-amyloid(25-35) on immortalised rat brain endothelial cell: protection by carnosine, homocarnosine and beta-alanine. Neurosci. Lett. 242:1998;105-108.
33. Rochel S., Margolis F.L. Carnosine release from olfactory bulb synaptosomes is calcium-dependent and depolarization-stimulated. J. Neurochem. 38:1982;1505-1514.
34. Rosen D.R., Siddique T., Patterson D., Figlewicz D.A., Sapp P., Hentati A., Donaldson D., Goto J., O'Regan J.P., Deng H.X.et al. Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis [published erratum appears in Nature 1993 Jul 22; 364 (6435): 362] [see comments]. Nature. 362:1993;59-62.
35. Sakai M., Yoshida M., Karasawa N., Teramura M., Ueda H., Nagatsu I. Carnosine-like immunoreactivity in the primary olfactory neuron of the rat. Experientia. 43:1987;298-300.
36. Sassoe-Pognetto M., Cantino D., Panzanelli P., Verdun di Cantogno L., Giustetto M., Margolis F.L., De Biasi S., Fasolo A. Presynaptic co-localization of carnosine and glutamate in olfactory neurones. NeuroReport. 5:1993;7-10.
37. Schulte S., Muller W.E., Friedberg K.D. In vitro and in vivo effects of lead on specific 3H-PN200-110 binding to dihydropyridine receptors in the frontal cortex of the mouse brain. Toxicology. 97:1995;113-121.
38. P.Q. Trombley, L.J. Blakemore. Mammalian olfactory bulb neurons, in: L.W. Haynes (Ed.), The Neuron in Tissue Culture, Vol. 18, Wiley, West Sussex, UK, 1999, pp. 585-592.
39. Trombley P.Q., Horning M.S., Blakemore L.J. Carnosine modulates zinc and copper effects on amino acid receptors and synaptic transmission [In Process Citation]. NeuroReport. 9:1998;3503-3507.
40. Trombley P.Q., Shepherd G.M. Differential modulation by zinc and copper of amino acid receptors from rat olfactory bulb neurons. J. Neurophysiol. 76:1996;2536-2546.
41. Tumer Z., Horn N. Menkes disease: recent advances and new aspects. J. Med. Genet. 34:1997;265-274.
42. Vlachova V., Zemkova H., Vyklicky L. Jr. Copper modulation of NMDA responses in mouse and rat cultured hippocampal neurons. Eur. J. Neurosci. 8:1996;2257-2264.
43. Weiser T., Wienrich M. The effects of copper ions on glutamate receptors in cultured rat cortical neurons. Brain Res. 742:1996;211-218.
44. Weiss J.H., Hartley D.M., Koh J.Y., Choi D.W. AMPA receptor activation potentiates zinc neurotoxicity. Neuron. 10:1993;43-49.
45. Yin H.Z., Weiss J.H. Zn(2+) permeates Ca(2+) permeable AMPA/kainate channels and triggers selective neural injury. NeuroReport. 6:1995;2553-2556.