-
1
-
-
0019133661
-
Mutations affecting segment number and polarity in Drosophila
-
DOI 10.1038/287795a0
-
C Nüsslein-Volhard E Wieschaus 1980 Mutations affecting segment number and polarity in drosophila Nature 287 795 801 10.1038/287795a0 6776413 (Pubitemid 11214475)
-
(1980)
Nature
, vol.287
, Issue.5785
, pp. 795-801
-
-
Nusslein-Volhard, C.1
Wieschaus, E.2
-
2
-
-
0033916281
-
Hedgehog signals regulate multiple aspects of gastrointestinal development
-
M Ramalho-Santos DA Melton AP McMahon 2000 Hedgehog signals regulate multiple aspects of gastrointestinal development Development 127 2763 2772 1:CAS:528:DC%2BD3cXkslOrs70%3D 10821773 (Pubitemid 30426822)
-
(2000)
Development
, vol.127
, Issue.12
, pp. 2763-2772
-
-
Ramalho-Santos, M.1
Melton, D.A.2
McMahon, A.P.3
-
3
-
-
16844362860
-
Evidence that loss of sonic hedgehog is an indicator of Helicobater pylori-induced atrophic gastritis progressing to gastric cancer
-
DOI 10.1111/j.1572-0241.2005.41001.x
-
A Shiotani H Iishi N Uedo S Ishiguro M Tatsuta Y Nakae M Kumamoto JL Merchant 2005 Evidence that loss of sonic hedgehog is an indicator of Helicobater pylori-induced atrophic gastritis progressing to gastric cancer Am J Gastroenterol 100 581 587 10.1111/j.1572-0241.2005.41001.x 1:CAS:528: DC%2BD2MXjsV2mtrg%3D 15743355 (Pubitemid 40487556)
-
(2005)
American Journal of Gastroenterology
, vol.100
, Issue.3
, pp. 581-587
-
-
Shiotani, A.1
Iishi, H.2
Uedo, N.3
Ishiguro, S.4
Tatsuta, M.5
Nakae, Y.6
Kumamoto, M.7
Merchant, J.L.8
-
4
-
-
0036839405
-
Sonic hedgehog expression correlates with fundic gland differentiation in the adult gastrointestinal tract
-
DOI 10.1136/gut.51.5.628
-
GR van den Brink JC Hardwick C Nielsen C Xu FJ ten Kate J Glickman SJ van Deventer DJ Roberts MP Peppelenbosch 2002 Sonic hedgehog expression correlates with fundic gland differentiation in the adult gastrointestinal tract Gut 51 628 633 10.1136/gut.51.5.628 12377798 (Pubitemid 35216847)
-
(2002)
Gut
, vol.51
, Issue.5
, pp. 628-633
-
-
Van Den Brink, G.R.1
Hardwick, J.C.H.2
Nielsen, C.3
Xu, C.4
Ten Kate, F.J.5
Glickman, J.6
Van Deventer, S.J.H.7
Roberts, D.J.8
Peppelenbosch, M.P.9
-
5
-
-
75149149098
-
Loss of parietal cell expression of sonic hedgehog induces hypergastrinemia and hyperproliferation of surface mucous cells
-
10.1053/j.gastro.2009.11.002 1:CAS:528:DC%2BC3cXivVCnsr0%3D 19909751
-
C Xiao SA Ogle MA Schumacher MA Orr-Asman ML Miller N Lertkowit A Varro F Hollande Y Zavros 2010 Loss of parietal cell expression of sonic hedgehog induces hypergastrinemia and hyperproliferation of surface mucous cells Gastroenterology 138 550 561 10.1053/j.gastro.2009.11.002 1:CAS:528: DC%2BC3cXivVCnsr0%3D 19909751
-
(2010)
Gastroenterology
, vol.138
, pp. 550-561
-
-
Xiao, C.1
Ogle, S.A.2
Schumacher, M.A.3
Orr-Asman, M.A.4
Miller, M.L.5
Lertkowit, N.6
Varro, A.7
Hollande, F.8
Zavros, Y.9
-
6
-
-
27144541492
-
Frequent activation of the hedgehog pathway in advanced gastric adenocarcinomas
-
DOI 10.1093/carcin/bgi130
-
X Ma K Chen S Huang X Zhang PA Adegboyega BM Evers H Zhang J Xie 2005 Frequent activation of the hedgehog pathway in advanced gastric adenocarcinomas Carcinogenesis 26 1698 1705 10.1093/carcin/bgi130 1:CAS:528:DC%2BD2MXhtVWnt7bO 15905200 (Pubitemid 41487985)
-
(2005)
Carcinogenesis
, vol.26
, Issue.10
, pp. 1698-1705
-
-
Ma, X.1
Chen, K.2
Huang, S.3
Zhang, X.4
Adegboyega, P.A.5
Evers, B.M.6
Zhang, H.7
Xie, J.8
-
7
-
-
0242268525
-
Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours
-
DOI 10.1038/nature01972
-
DM Berman SS Karhadkar A Maitra R Montes De Oca MR Gerstenblith K Briggs AR Parker Y Shimada JR Eshleman DN Watkins PA Beachy 2003 Widespread requirement for hedgehog ligand stimulation in growth of digestive tract tumours Nature 425 846 851 10.1038/nature01972 1:CAS:528:DC%2BD3sXotlWqsLc%3D 14520411 (Pubitemid 37351469)
-
(2003)
Nature
, vol.425
, Issue.6960
, pp. 846-851
-
-
Berman, D.M.1
Karhadkar, S.S.2
Maitra, A.3
De Oca, R.M.4
Gerstenblith, M.R.5
Briggs, K.6
Parker, A.R.7
Shimada, Y.8
Eshleman, J.R.9
Watkins, D.N.10
Beachy, P.A.11
-
8
-
-
0028948811
-
The product of hedgehog autoproteolytic cleavage active in local and long-range signalling
-
10.1038/374363a0 1:CAS:528:DyaK2MXksFKmsr4%3D 7885476
-
JA Porter DP von Kessler SC Ekker KE Young JJ Lee K Moses PA Beachy 1995 The product of hedgehog autoproteolytic cleavage active in local and long-range signalling Nature 374 363 366 10.1038/374363a0 1:CAS:528:DyaK2MXksFKmsr4%3D 7885476
-
(1995)
Nature
, vol.374
, pp. 363-366
-
-
Porter, J.A.1
Von Kessler, D.P.2
Ekker, S.C.3
Young, K.E.4
Lee, J.J.5
Moses, K.6
Beachy, P.A.7
-
9
-
-
33645228803
-
A highly conserved amino-terminal region of Sonic Hedgehog is required for the formation of its freely diffusible multimeric form
-
DOI 10.1074/jbc.M511427200
-
JA Goetz S Singh LM Suber FJ Kull DJ Robbins 2006 A highly conserved amino-terminal region of sonic hedgehog is required for the formation of its freely diffusible multimeric form J Biol Chem 281 4087 4093 10.1074/jbc. M511427200 1:CAS:528:DC%2BD28XhtlKkt7c%3D 16339763 (Pubitemid 43847834)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.7
, pp. 4087-4093
-
-
Goetz, J.A.1
Singh, S.2
Suber, L.M.3
Kull, F.J.4
Robbins, D.J.5
-
10
-
-
23444443064
-
Mechanisms of Hedgehog gradient formation and interpretation
-
DOI 10.1002/neu.20168
-
C Torroja N Gorfinkiel I Guerrero 2005 Mechanisms of hedgehog gradient formation and interpretation J Neurobiol 64 334 356 10.1002/neu.20168 1:CAS:528:DC%2BD2MXpvVWrtbY%3D 16041759 (Pubitemid 41114044)
-
(2005)
Journal of Neurobiology
, vol.64
, Issue.4
, pp. 334-356
-
-
Torroja, C.1
Gorfinkiel, N.2
Guerrero, I.3
-
11
-
-
2942742564
-
Novel lipid modifications of secreted protein signals
-
DOI 10.1146/annurev.biochem.73.011303.073933
-
RK Mann P Beachy 2004 Novel lipid modifications of secreted protein signals Ann Rev Biochem 73 891 923 10.1146/annurev.biochem.73.011303.073933 1:CAS:528:DC%2BD2cXmslagsb0%3D 15189162 (Pubitemid 39050389)
-
(2004)
Annual Review of Biochemistry
, vol.73
, pp. 891-923
-
-
Mann, R.K.1
Beachy, P.A.2
-
12
-
-
15444359695
-
Identification of a palmitic acid-modified form of human Sonic hedgehog
-
DOI 10.1074/jbc.273.22.14037
-
RB Pepinsky C Zeng D Wen P Rayhorn DP Baker KP Williams SA Bixler CM Ambrose EA Garber K Miatkowski FR Taylor EA Wang A Galdes 1998 Identification of a palmitic acid-modified form of human sonic hedgehog J Biol Chem 273 14037 14045 10.1074/jbc.273.22.14037 1:CAS:528:DyaK1cXjvVeis7Y%3D 9593755 (Pubitemid 28268461)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.22
, pp. 14037-14045
-
-
Pepinsky, R.B.1
Zeng, C.2
Went, D.3
Rayhorn, P.4
Baker, D.P.5
Williams, K.P.6
Bixler, S.A.7
Ambrose, C.M.8
Garber, E.A.9
Miatkowski, K.10
Taylor, F.R.11
Wang, E.A.12
Galdes, A.13
-
13
-
-
0030027059
-
Conservation of the hedgehog/patched signaling pathway from flies to mice: Induction of a mouse patched gene by Hedgehog
-
LV Goodrich RL Johnson L Milenkovic JA McMahon MP Scott 1996 Conservation of the hedgehog/patched signaling pathway from flies to mice: induction of a mouse patched gene by hedgehog Genes Dev 10 301 312 10.1101/gad.10.3.301 1:CAS:528:DyaK28XhtFSiurs%3D 8595881 (Pubitemid 26058963)
-
(1996)
Genes and Development
, vol.10
, Issue.3
, pp. 301-312
-
-
Goodrich, L.V.1
Johnson, R.L.2
Milenkovic, L.3
McMahon, J.A.4
Scott, M.P.5
-
14
-
-
0037158748
-
Patched acts catalytically to suppress the activity of smoothened
-
DOI 10.1038/nature00989
-
J Taipale MK Cooper T Maiti PA Beachy 2002 Patched acts catalytically to suppress the activity of smoothened Nature 418 892 896 10.1038/nature00989 1:CAS:528:DC%2BD38XmtlWltb0%3D 12192414 (Pubitemid 34966310)
-
(2002)
Nature
, vol.418
, Issue.6900
, pp. 892-897
-
-
Taipale, J.1
Cooper, M.K.2
Maiti, T.3
Beachy, P.A.4
-
15
-
-
0028281306
-
Expression of three mouse homologs of the drosophila segment polarity gene cubitus interruptus, Gli, Gli-2, and Gli-3, in ectoderm- and mesoderm-derived tissues suggests multiple roles during postimplantation development
-
DOI 10.1006/dbio.1994.1097
-
CC Hui D Slusarski KA Platt R Holmgren AL Joyner 1994 Expression of three mouse homologs of the drosophila segment polarity gene cubitus interruptus, gli, gli-2, and gli-3, in ectoderm- and mesoderm-derived tissues suggests multiple roles during postimplantation development Dev Biol 162 402 413 10.1006/dbio.1994.1097 1:CAS:528:DyaK2cXmsFWmt7k%3D 8150204 (Pubitemid 24144119)
-
(1994)
Developmental Biology
, vol.162
, Issue.2
, pp. 402-413
-
-
Hui, C.-C.1
Slusarski, D.2
Platt, K.A.3
Holmgren, R.4
Joyner, A.L.5
-
16
-
-
34247491334
-
Gli1 acts through Snail and E-cadherin to promote nuclear signaling by β-catenin
-
DOI 10.1038/sj.onc.1210241, PII 1210241
-
LiX DW SM Lobo-Ruppert JM Ruppert 2007 Gli1 acts through snail and E-cadherin to promote nuclear signaling by beta-catenin Oncogene 26 4489 4498 10.1038/sj.onc.1210241 (Pubitemid 47037042)
-
(2007)
Oncogene
, vol.26
, Issue.31
, pp. 4489-4498
-
-
Li, X.1
Deng, W.2
Lobo-Ruppert, S.M.3
Ruppert, J.M.4
-
17
-
-
31544480393
-
Snail induction is an early response to Gli1 that determines the efficiency of epithelial transformation
-
DOI 10.1038/sj.onc.1209077, PII 1209077
-
X Li W Deng CD Nail SK Bailey MH Kraus JM Ruppert SM Lobo-Ruppert 2006 Snail induction is an early response to gli1 that determines the efficiency of epithelial transformation Oncogene 25 609 621 1:CAS:528:DC%2BD28XnsFSjsg%3D%3D 16158046 (Pubitemid 43164471)
-
(2006)
Oncogene
, vol.25
, Issue.4
, pp. 609-621
-
-
Li, X.1
Deng, W.2
Nail, C.D.3
Bailey, S.K.4
Kraus, M.H.5
Ruppert, J.M.6
Lobo-Ruppert, S.M.7
-
18
-
-
18144388632
-
Regulation and function of the sonic hedgehog signal transduction pathway in isolated gastric parietal cells
-
DOI 10.1074/jbc.M413037200
-
V Stepan S Ramamoorthy H Nitsche Y Zavros JL Merchant A Todisco 2005 Regulation and function of the sonic hedgehog signal transduction pathway in isolated gastric parietal cells J Biol Chem 280 15700 15708 10.1074/jbc. M413037200 1:CAS:528:DC%2BD2MXjtleis74%3D 15691835 (Pubitemid 40616689)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.16
, pp. 15700-15708
-
-
Stepan, V.1
Ramamoorthy, S.2
Nitsche, H.3
Zavros, Y.4
Merchant, J.L.5
Todisco, A.6
-
19
-
-
36349013850
-
Reduced pepsin A processing of sonic hedgehog in parietal cells precedes gastric atrophy and transformation
-
DOI 10.1074/jbc.M707090200
-
Y Zavros M Waghray A Tessier A Todisco DL Gumucio LC Samuelson A Dlugosz JL Merchant 2007 Reduced pepsin a processing of sonic hedgehog in parietal cells precedes gastric atrophy and transformation J Biol Chem 282 33265 33274 10.1074/jbc.M707090200 1:CAS:528:DC%2BD2sXht1Oru7bP 17872943 (Pubitemid 350159511)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.46
, pp. 33265-33272
-
-
Zavros, Y.1
Waghray, M.2
Tessier, A.3
Bai, L.4
Todisco, A.5
Gumucio, D.L.6
Samuelson, L.C.7
Dlugosz, A.8
Merchant, J.L.9
-
20
-
-
75149191890
-
Interleukin-1beta promotes gastric atrophy through suppression of sonic hedgehog
-
10.1053/j.gastro.2009.10.043 1:CAS:528:DC%2BC3cXivVCnsro%3D
-
M Waghray Y Zavros M Saqui-Salces M El-Zaatari CB Alamelumangapuram A Todisco KA Eaton JL Merchant 2010 Interleukin-1beta promotes gastric atrophy through suppression of sonic hedgehog Gastrotenterology 138 562 572 10.1053/j.gastro.2009.10.043 1:CAS:528:DC%2BC3cXivVCnsro%3D
-
(2010)
Gastrotenterology
, vol.138
, pp. 562-572
-
-
Waghray, M.1
Zavros, Y.2
Saqui-Salces, M.3
El-Zaatari, M.4
Alamelumangapuram, C.B.5
Todisco, A.6
Eaton, K.A.7
Merchant, J.L.8
-
21
-
-
51149106366
-
Sonic hedgehog is associated with h +, k + -ATPase-containing membranes in gastric parietal cells and secreted with histamine stimulation
-
1:CAS:528:DC%2BD1cXoslygsrY%3D
-
Y Zavros M Orr C Xiao DH Malinowska 2008 Sonic hedgehog is associated with h +, k + -ATPase-containing membranes in gastric parietal cells and secreted with histamine stimulation Am J Physiol 295 G99 G111 1:CAS:528:DC%2BD1cXoslygsrY%3D
-
(2008)
Am J Physiol
, vol.295
-
-
Zavros, Y.1
Orr, M.2
Xiao, C.3
Malinowska, D.H.4
-
22
-
-
0042707747
-
Targeting of proteins to membranes through hedgehog auto-processing
-
DOI 10.1038/nbt844
-
S Vincent A Thomas B Brasher JD Benson 2003 Targeting of proteins to membranes through hedgehog auto-processing Nat Biotechnol 21 936 940 10.1038/nbt844 1:CAS:528:DC%2BD3sXlvVKgtbY%3D 12858181 (Pubitemid 36936202)
-
(2003)
Nature Biotechnology
, vol.21
, Issue.8
, pp. 936-940
-
-
Vincent, S.1
Thomas, A.2
Brasher, B.3
Benson, J.D.4
-
23
-
-
33646357266
-
Pepstatin A, an aspartic proteinase inhibitor, suppresses RANKL-induced osteoclast differentiation
-
DOI 10.1093/jb/mvj066
-
H Yoshida K Okamoto T Iwamoto E Sakai K Kanaoka JP Hu M Shibata H Hotokezaka K Nishishita A Mizuno Y Kato 2006 Pepstatin A, an aspartic proteinase inhibitor, suppresses rankl-induced osteoclast differentiation J Biochem 139 583 590 10.1093/jb/mvj066 1:CAS:528:DC%2BD28XkslOnsLg%3D 16567424 (Pubitemid 43667123)
-
(2006)
Journal of Biochemistry
, vol.139
, Issue.3
, pp. 583-590
-
-
Yoshida, H.1
Okamoto, K.2
Iwamoto, T.3
Sakai, E.4
Kanaoka, K.5
Hu, J.-P.6
Shibata, M.7
Hotokezaka, H.8
Nishishita, K.9
Mizuno, A.10
Kato, Y.11
-
24
-
-
33646102912
-
Sonic hedgehog stimulates the proliferation of rat gastric mucosal cells through erk activation by elevating intracellular calcium concentration
-
10.1016/j.bbrc.2006.03.188 1:CAS:528:DC%2BD28XjvFWnsrs%3D 16630542
-
H Osawa H Ohnishi K Takano T Noguti H Mashima H Hoshino H Kita K Sato H Matsui K Sugano 2006 Sonic hedgehog stimulates the proliferation of rat gastric mucosal cells through erk activation by elevating intracellular calcium concentration Biochem Biophys Res Commun 344 680 687 10.1016/j.bbrc.2006.03.188 1:CAS:528:DC%2BD28XjvFWnsrs%3D 16630542
-
(2006)
Biochem Biophys Res Commun
, vol.344
, pp. 680-687
-
-
Osawa, H.1
Ohnishi, H.2
Takano, K.3
Noguti, T.4
Mashima, H.5
Hoshino, H.6
Kita, H.7
Sato, K.8
Matsui, H.9
Sugano, K.10
-
25
-
-
0029063897
-
Specific immunocytochemical localization of cathepsin e at the ruffled border membrane of active osteoclasts
-
10.1007/BF00307961 1:CAS:528:DyaK2MXntV2kt7c%3D 7621529
-
Y Yoshimine T Tsukuba R Isobe M Sumi A Akamine K Maeda K Yamamoto 1995 Specific immunocytochemical localization of cathepsin E at the ruffled border membrane of active osteoclasts Cell Tissue Res 281 85 91 10.1007/BF00307961 1:CAS:528:DyaK2MXntV2kt7c%3D 7621529
-
(1995)
Cell Tissue Res
, vol.281
, pp. 85-91
-
-
Yoshimine, Y.1
Tsukuba, T.2
Isobe, R.3
Sumi, M.4
Akamine, A.5
Maeda, K.6
Yamamoto, K.7
-
26
-
-
9444265320
-
Gastric cancer originating from bone marrow-derived cells
-
DOI 10.1126/science.1099513
-
J Houghton C Stoicov S Nomura AB Rogers J Carlson H Li X Cai JG Fox JR Goldenring TC Wang 2004 Gastric cancer originating from bone marrow-derived cells Science 306 1568 1571 10.1126/science.1099513 1:CAS:528:DC%2BD2cXhtVCisLbE 15567866 (Pubitemid 39564955)
-
(2004)
Science
, vol.306
, Issue.5701
, pp. 1568-1571
-
-
Houghton, J.1
Stoicov, C.2
Nomura, S.3
Rogers, A.B.4
Carlson, J.5
Li, H.6
Cai, X.7
Fox, J.G.8
Goldenring, J.R.9
Wang, T.C.10
-
27
-
-
28444434457
-
Gli3 null mice display glandular overgrowth of the developing stomach
-
DOI 10.1002/dvdy.20542
-
JH Kim Z Huang R Mo 2005 Gli3 null mice display glandular overgrowth of the developing stomach Dev Dyn 234 984 991 10.1002/dvdy.20542 1:CAS:528:DC%2BD2MXhtlCisrjF 16247775 (Pubitemid 41741169)
-
(2005)
Developmental Dynamics
, vol.234
, Issue.4
, pp. 984-991
-
-
Kim, J.H.1
Huang, Z.2
Mo, R.3
-
28
-
-
19944381545
-
Down-regulation of a morphogen (sonic hedgehog) gradient in the gastric epithelium of Helicobacter pylori-infected Mongolian gerbils
-
DOI 10.1002/path.1763
-
H Suzuki Y Minegishi Y Nomoto T Ota T Masaoka GR van den Brink T Hibi 2005 Down-regulation of a morphogen (Sonic hedgehog) gradient in the gastric epithelium of Helicobacter pylori-infected Mongolian gerbils J Pathol 206 186 197 10.1002/path.1763 1:CAS:528:DC%2BD2MXlsFejtbc%3D 15818572 (Pubitemid 40754022)
-
(2005)
Journal of Pathology
, vol.206
, Issue.2
, pp. 186-197
-
-
Suzuki, H.1
Minegishi, Y.2
Nomoto, Y.3
Ota, T.4
Masaoka, T.5
Van Den Brink, G.R.6
Hibi, T.7
-
29
-
-
38149027631
-
Cyclopamine inhibition of the sonic hedgehog pathway in the stomach requires concomitant acid inhibition
-
10.1016/j.regpep.2007.09.020 1:CAS:528:DC%2BD1cXosFKhtw%3D%3D 17996964
-
M El-Zaatari A Grabowska AJ McKenzie DG Powe PJ Scotting SA Watson 2008 Cyclopamine inhibition of the sonic hedgehog pathway in the stomach requires concomitant acid inhibition Regul Pept 146 131 139 10.1016/j.regpep.2007.09.020 1:CAS:528:DC%2BD1cXosFKhtw%3D%3D 17996964
-
(2008)
Regul Pept
, vol.146
, pp. 131-139
-
-
El-Zaatari, M.1
Grabowska, A.2
McKenzie, A.J.3
Powe, D.G.4
Scotting, P.J.5
Watson, S.A.6
-
30
-
-
34250336769
-
De-regulation of the sonic hedgehog pathway in the InsGas mouse model of gastric carcinogenesis
-
DOI 10.1038/sj.bjc.6603782, PII 6603782
-
M El-Zaatari A Tobias AM Grabowska R Kumari PJ Scotting P Kaye J Atherton PA Clarke DG Powe SA Watson 2007 De-regulation of the sonic hedgehog pathway in the insgas mouse model of gastric carcinogenesis Br J Cancer 96 1855 1861 10.1038/sj.bjc.6603782 1:CAS:528:DC%2BD2sXmtlyqtb8%3D 17505514 (Pubitemid 46912013)
-
(2007)
British Journal of Cancer
, vol.96
, Issue.12
, pp. 1855-1861
-
-
El-Zaatari, M.1
Tobias, A.2
Grabowska, A.M.3
Kumari, R.4
Scotting, P.J.5
Kaye, P.6
Atherton, J.7
Clarke, P.A.8
Powe, D.G.9
Watson, S.A.10
-
31
-
-
0035856021
-
Helicobacter pylori infection and the development of gastric cancer
-
10.1056/NEJMoa001999 1:STN:280:DC%2BD3MrgslCqtA%3D%3D 11556297
-
N Uemura S Okamoto S Yamamoto N Matsumura S Yamaguchi M Yamakido K Taniyama N Sasaki RJ Schlemper 2001 Helicobacter pylori infection and the development of gastric cancer N Engl J Med 345 784 789 10.1056/NEJMoa001999 1:STN:280:DC%2BD3MrgslCqtA%3D%3D 11556297
-
(2001)
N Engl J Med
, vol.345
, pp. 784-789
-
-
Uemura, N.1
Okamoto, S.2
Yamamoto, S.3
Matsumura, N.4
Yamaguchi, S.5
Yamakido, M.6
Taniyama, K.7
Sasaki, N.8
Schlemper, R.J.9
-
32
-
-
0016705559
-
A model for gastric cancer epidemiology
-
10.1016/S0140-6736(75)90498-5 1:STN:280:DyaE2M7ptlGjsA%3D%3D 49653
-
P Correa W Haenszel C Cuello S Tannenbaum M Archer 1975 A model for gastric cancer epidemiology Lancet 2 58 60 10.1016/S0140-6736(75)90498-5 1:STN:280:DyaE2M7ptlGjsA%3D%3D 49653
-
(1975)
Lancet
, vol.2
, pp. 58-60
-
-
Correa, P.1
Haenszel, W.2
Cuello, C.3
Tannenbaum, S.4
Archer, M.5
-
33
-
-
34547549860
-
Carcinogenesis of Helicobacter pylori
-
DOI 10.1053/j.gastro.2007.06.026, PII S0016508507011675
-
P Correa J Houghton 2007 Carcinogenesis of Helicobacter pylori Gastroenterology 133 659 672 10.1053/j.gastro.2007.06.026 1:CAS:528: DC%2BD2sXhtVWqsrrM 17681184 (Pubitemid 47187360)
-
(2007)
Gastroenterology
, vol.133
, Issue.2
, pp. 659-672
-
-
Correa, P.1
Houghton, J.2
-
35
-
-
34247843997
-
Hedgehog signaling pathway and gastrointestinal stem cell signaling network (review)
-
1:CAS:528:DC%2BD28XhtlCgtb3O 17089004
-
Y Katoh M Katoh 2006 Hedgehog signaling pathway and gastrointestinal stem cell signaling network (review) Int J Mol Med 18 1019 1023 1:CAS:528: DC%2BD28XhtlCgtb3O 17089004
-
(2006)
Int J Mol Med
, vol.18
, pp. 1019-1023
-
-
Katoh, Y.1
Katoh, M.2
-
36
-
-
0347995025
-
Transcription of Sonic Hedgehog, a Potential Factor for Gastric Morphogenesis and Gastric Mucosa Maintenance, Is Up-regulated in Acidic Conditions
-
DOI 10.1097/01.LAB.0000101729.25140.0C
-
A Dimmler T Brabletz F Hlubek M Hafner T Rau T Kirchner G Faller 2003 Transcription of sonic hedgehog, a potential factor for gastric morphogenesis and gastric mucosa maintenance, is up-regulated in acidic conditions Lab Invest 83 1829 1837 10.1097/01.LAB.0000101729.25140.0C 1:CAS:528:DC%2BD3sXpsl2ms7w%3D 14691301 (Pubitemid 38018546)
-
(2003)
Laboratory Investigation
, vol.83
, Issue.12
, pp. 1829-1837
-
-
Dimmler, A.1
Brabletz, T.2
Hlubek, F.3
Hafner, M.4
Rau, T.5
Kirchner, T.6
Faller, G.7
-
37
-
-
35348941302
-
Reduced Shh expression in TFF2-overexpressing lesions of the gastric fundus under hypochlorhydric conditions
-
DOI 10.1002/path.2221
-
Y Minegishi H Suzuki M Arakawa Y Fukushima T Masaoka T Ishikawa NA Wright T Hibi 2007 Reduced shh expression in tff2-overexpressing lesions of the gastric fundus under hypochlorhydric conditions J Pathol 213 161 169 10.1002/path.2221 1:CAS:528:DC%2BD2sXhtlWjsLrM 17763396 (Pubitemid 47612238)
-
(2007)
Journal of Pathology
, vol.213
, Issue.2
, pp. 161-169
-
-
Minegishi, Y.1
Suzuki, H.2
Arakawa, M.3
Fukushima, Y.4
Masaoka, T.5
Ishikawa, T.6
Wright, N.A.7
Hibi, T.8
-
38
-
-
0242363135
-
Treatment of Helicobacter gastritis with IL-4 requires somatostatin
-
DOI 10.1073/pnas.2135193100
-
Y Zavros S Rathinavelu JY Kao A Todisco J Del Valle JV Weinstock MJ Low JL Merchant 2003 Treatment of Helicobacter gastritis with il-4 requires somatostatin Proc Natl Acad Sci U S A 100 12944 12949 10.1073/pnas.2135193100 1:CAS:528:DC%2BD3sXoslKmsr8%3D 14555768 (Pubitemid 37340005)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.22
, pp. 12944-12949
-
-
Zavros, Y.1
Rathinavelu, S.2
Kao, J.Y.3
Todisco, A.4
Del Valle, J.5
Weinstock, J.V.6
Low, M.J.7
Merchant, J.L.8
-
39
-
-
0034704880
-
Interleukin-1 polymorphisms associated with increased risk of gastric cancer
-
DOI 10.1038/35006081
-
EM El-Omar M Carrington WH Chow KE McColl JH Bream HA Young J Herrera J Lissowska CC Yuan N Rothman G Lanyon M Martin JF Fraumeni Jr CS Rabkin 2000 Interleukin-1 polymorphisms associated with increased risk of gastric cancer Nature 404 398 402 10.1038/35006081 1:CAS:528:DC%2BD3cXitlyltb4%3D 10746728 (Pubitemid 30164342)
-
(2000)
Nature
, vol.404
, Issue.6776
, pp. 398-402
-
-
El-Omar, E.M.1
Carrington, M.2
Chow, W.-H.3
McColl, K.E.L.4
Bream, J.H.5
Young, H.A.6
Herrera, J.7
Lissowska, J.8
Yuan, C.-C.9
Rothman, N.10
Lanyon, G.11
Martin, M.12
Fraumeni Jr., J.F.13
Rabkin, C.S.14
-
40
-
-
0034744083
-
The importance of interleukin 1 β in Helicobacter pylori associated disease
-
DOI 10.1136/gut.48.6.743
-
EM El-Omar 2001 The importance of interleukin 1beta in Helicobacter pylori-associated disease Gut 48 743 747 10.1136/gut.48.6.743 1:STN:280:DC%2BD3M3mslyqsQ%3D%3D 11358884 (Pubitemid 32476967)
-
(2001)
Gut
, vol.48
, Issue.6
, pp. 743-747
-
-
El-Omar, E.M.1
-
41
-
-
0035665558
-
+-ATPase β-subunit- and gastrin-deficient mice
-
TV Franic L Judd D Robinson SP Barrett KL Scarff PA Gleeson LC Samuelson IR Van Driel 2001 Regulation of gastric epithelial cell development revealed in h(+)/k(+)-ATPase beta-subunit- and gastrin-deficient mice Am J Physiol 281 G1502 G1511 1:CAS:528:DC%2BD3MXptlKmur8%3D (Pubitemid 33775102)
-
(2001)
American Journal of Physiology
, vol.281
, Issue.PART 1
-
-
Franic, T.V.1
Judd, L.M.2
Robinson, D.3
Barrett, S.P.4
Scarff, K.L.5
Gleeson, P.A.6
Samuelson, L.C.7
Van Driel, I.R.8
-
42
-
-
28244447471
-
P53-independent negative regulation of p21/cyclin-dependent kinase-interacting protein 1 by the Sonic Hedgehog-glioma-associated oncogene 1 pathway in gastric carcinoma cells
-
DOI 10.1158/0008-5472.CAN-05-0777
-
M Ohta K Tateishi F Kanai H Watabe S Kondo B Guleng Y Tanaka Y Asaoka A Jazag J Imamura H Ijichi T Ikenoue M Sata M Miyagishi K Taira M Tada T Kawabe M Omata 2005 P53-independent negative regulation of p21/cyclin-dependent kinase-interacting protein 1 by the sonic hedgehog-glioma-associated oncogene 1 pathway in gastric carcinoma cells Cancer Res 65 10822 10829 10.1158/0008-5472.CAN-05-0777 1:CAS:528:DC%2BD2MXht1Kjsr7F 16322228 (Pubitemid 41713349)
-
(2005)
Cancer Research
, vol.65
, Issue.23
, pp. 10822-10829
-
-
Ohta, M.1
Tateishi, K.2
Kanai, F.3
Watabe, H.4
Kondo, S.5
Guleng, B.6
Tanaka, Y.7
Asaoka, Y.8
Jazag, A.9
Imamura, J.10
Ijichi, H.11
Ikenoue, T.12
Sata, M.13
Miyagishi, M.14
Taira, K.15
Tada, M.16
Kawabe, T.17
Omata, M.18
-
43
-
-
0030878456
-
Mechanisms involved in Helicobacter pylori-induced interleukin-8 production by a gastric cancer cell line, MKN45
-
M Aihara D Tsuchimoto H Takizawa A Azuma H Wakebe Y Ohmoto K Imagawa M Kikuchi N Mukaida K Matsushima 1997 Mechanisms involved in Helicobacter pylori-induced interleukin-8 production by a gastric cancer cell line, mkn45 Infect Immun 65 3218 3224 1:CAS:528:DyaK2sXkvVakurw%3D 9234778 (Pubitemid 27342402)
-
(1997)
Infection and Immunity
, vol.65
, Issue.8
, pp. 3218-3224
-
-
Aihara, M.1
Tsuchimoto, D.2
Takizawa, H.3
Azuma, A.4
Wakebe, H.5
Ohmoto, Y.6
Imagawa, K.7
Kikuchi, M.8
Mukaida, N.9
Matsushima, K.10
-
44
-
-
0037289832
-
Role of NF-κB and AP-1 on Helicobater pylori-induced IL-8 expression in AGS cells
-
DOI 10.1023/A:1021963007225
-
SH Chu H Kim JY Seo JW Lim N Mukaida KH Kim 2003 Role of NF-kappab and ap-1 on Helicobater pylori-induced il-8 expression in ags cells Dig Dis Sci 48 257 265 10.1023/A:1021963007225 12643600 (Pubitemid 36232989)
-
(2003)
Digestive Diseases and Sciences
, vol.48
, Issue.2
, pp. 257-265
-
-
Chu, S.H.1
Kim, H.2
Seo, J.Y.3
Lim, J.W.4
Mukaida, N.5
Kim, K.H.6
-
45
-
-
58249124375
-
Characterization of sonic hedgehog as a novel NF-kappab target gene that promotes NF-kappab-mediated apoptosis resistance and tumor growth in vivo
-
10.1096/fj.08-111096 1:CAS:528:DC%2BD1MXlsVOmsw%3D%3D 18772349
-
H Kasperczyk B Baumann KM Debatin S Fulda 2009 Characterization of sonic hedgehog as a novel NF-kappab target gene that promotes NF-kappab-mediated apoptosis resistance and tumor growth in vivo FASEB J 23 21 33 10.1096/fj.08-111096 1:CAS:528:DC%2BD1MXlsVOmsw%3D%3D 18772349
-
(2009)
FASEB J
, vol.23
, pp. 21-33
-
-
Kasperczyk, H.1
Baumann, B.2
Debatin, K.M.3
Fulda, S.4
-
46
-
-
4143114809
-
Hedgehog signalling in foregut malignancy
-
DOI 10.1016/j.bcp.2004.04.025, PII S0006295204003612
-
DN Watkins C Peacock 2004 Hedgehog signaling in foregut malignancy Biochem Pharmacol 68 1055 1060 10.1016/j.bcp.2004.04.025 1:CAS:528: DC%2BD2cXmslOnsr8%3D 15313401 (Pubitemid 39094270)
-
(2004)
Biochemical Pharmacology
, vol.68
, Issue.6
, pp. 1055-1060
-
-
Watkins, D.N.1
Peacock, C.D.2
-
47
-
-
0242669237
-
Hedgehog signalling within airway epithelial progenitors and in small-cell lung cancer
-
DOI 10.1038/nature01493
-
DN Watkins DM Berman SG Burkholder B Wang PA Beachy SB Baylin 2003 Hedgehog signalling within airway epithelial progenitors and in small-cell lung cancer Nature 422 313 317 10.1038/nature01493 1:CAS:528:DC%2BD3sXitFKmu7s%3D 12629553 (Pubitemid 36378358)
-
(2003)
Nature
, vol.422
, Issue.6929
, pp. 313-317
-
-
Watkins, D.N.1
Berman, D.M.2
Burkholder, S.G.3
Wang, B.4
Beachy, P.A.5
Baylin, S.B.6
-
48
-
-
6044243650
-
Hedgehog signalling in prostate regeneration, neoplasia and metastasis
-
DOI 10.1038/nature02962
-
SS Karhadkar G Bova N Abdallah S Dhara D Gardner A Maitra JT Isaacs DM Berman PA Beachy 2004 Hedgehog signalling in prostate regeneration, neoplasia and metastasis Nature 431 707 712 10.1038/nature02962 1:CAS:528: DC%2BD2cXotFGru74%3D 15361885 (Pubitemid 39382619)
-
(2004)
Nature
, vol.431
, Issue.7009
, pp. 707-712
-
-
Karhadkar, S.S.1
Bova, G.S.2
Abdallah, N.3
Dhara, S.4
Gardner, D.5
Maitra, A.6
Isaacs, J.T.7
Berman, D.M.8
Beachy, P.A.9
-
49
-
-
61649090805
-
Stromal cell-derived factor 1/cxcr4 signaling is critical for the recruitment of mesenchymal stem cells to the fracture site during skeletal repair in a mouse model
-
10.1002/art.24330 1:CAS:528:DC%2BD1MXktVGmsb0%3D 19248097
-
T Kitaori H Ito EM Schwarz R Tsutsumi H Yoshitomi S Oishi M Nakano N Fujii T Nagasawa T Nakamura 2009 Stromal cell-derived factor 1/cxcr4 signaling is critical for the recruitment of mesenchymal stem cells to the fracture site during skeletal repair in a mouse model Arthritis Rheum 60 813 823 10.1002/art.24330 1:CAS:528:DC%2BD1MXktVGmsb0%3D 19248097
-
(2009)
Arthritis Rheum
, vol.60
, pp. 813-823
-
-
Kitaori, T.1
Ito, H.2
Schwarz, E.M.3
Tsutsumi, R.4
Yoshitomi, H.5
Oishi, S.6
Nakano, M.7
Fujii, N.8
Nagasawa, T.9
Nakamura, T.10
-
50
-
-
54349101485
-
Factors that influence short-term homing of human bone marrow-derived mesenchymal stem cells in a xenogeneic animal model
-
10.3324/haematol.12553 1:CAS:528:DC%2BD1cXhtl2gurzN 18728032
-
C Kyriakou N Rabin A Pizzey A Nathwani K Yong 2008 Factors that influence short-term homing of human bone marrow-derived mesenchymal stem cells in a xenogeneic animal model Haematologica 93 1457 1465 10.3324/haematol.12553 1:CAS:528:DC%2BD1cXhtl2gurzN 18728032
-
(2008)
Haematologica
, vol.93
, pp. 1457-1465
-
-
Kyriakou, C.1
Rabin, N.2
Pizzey, A.3
Nathwani, A.4
Yong, K.5
-
51
-
-
58149345104
-
Igf-1-overexpressing mesenchymal stem cells accelerate bone marrow stem cell mobilization via paracrine activation of sdf-1alpha/cxcr4 signaling to promote myocardial repair
-
10.1161/CIRCRESAHA.108.186742 1:CAS:528:DC%2BD1cXhtlKrt7fF 18948617
-
HKh Haider S Jiang NM Idris M Ashraf 2008 Igf-1-overexpressing mesenchymal stem cells accelerate bone marrow stem cell mobilization via paracrine activation of sdf-1alpha/cxcr4 signaling to promote myocardial repair Circ Res 103 1300 1308 10.1161/CIRCRESAHA.108.186742 1:CAS:528: DC%2BD1cXhtlKrt7fF 18948617
-
(2008)
Circ Res
, vol.103
, pp. 1300-1308
-
-
Hkh, H.1
Jiang, S.2
Idris, N.M.3
Ashraf, M.4
-
52
-
-
54549089856
-
Overexpression of interleukin-1beta induces gastric inflammation and cancer and mobilizes myeloid-derived suppressor cells in mice
-
10.1016/j.ccr.2008.10.011 1:CAS:528:DC%2BD1cXhtlOjsLrP 18977329
-
S Tu G Bhagat G Cui S Takaishi EA Kurt-Jones B Rickman KS Betz M Penz-Oesterreicher O Bjorkdahl JG Fox TC Wang 2008 Overexpression of interleukin-1beta induces gastric inflammation and cancer and mobilizes myeloid-derived suppressor cells in mice Cancer Cell 14 408 419 10.1016/j.ccr.2008.10.011 1:CAS:528:DC%2BD1cXhtlOjsLrP 18977329
-
(2008)
Cancer Cell
, vol.14
, pp. 408-419
-
-
Tu, S.1
Bhagat, G.2
Cui, G.3
Takaishi, S.4
Kurt-Jones, E.A.5
Rickman, B.6
Betz, K.S.7
Penz-Oesterreicher, M.8
Bjorkdahl, O.9
Fox, J.G.10
Wang, T.C.11
-
53
-
-
69249150822
-
A nanoparticle system specifically designed to deliver short interfering RNA inhibits tumor growth in vivo
-
10.1158/0008-5472.CAN-08-3945 1:CAS:528:DC%2BD1MXpvFejtro%3D 19654315
-
N Yagi I Manabe T Tottori A Ishihara F Ogata JH Kim S Nishimura K Fujiu Y Oishi K Itaka Y Kato M Yamauchi R Nagai 2009 A nanoparticle system specifically designed to deliver short interfering RNA inhibits tumor growth in vivo Cancer Res 69 6531 6538 10.1158/0008-5472.CAN-08-3945 1:CAS:528:DC%2BD1MXpvFejtro%3D 19654315
-
(2009)
Cancer Res
, vol.69
, pp. 6531-6538
-
-
Yagi, N.1
Manabe, I.2
Tottori, T.3
Ishihara, A.4
Ogata, F.5
Kim, J.H.6
Nishimura, S.7
Fujiu, K.8
Oishi, Y.9
Itaka, K.10
Kato, Y.11
Yamauchi, M.12
Nagai, R.13
-
54
-
-
37749027080
-
Small molecules in stem cell self-renewal and differentiation
-
10.1038/sj.gt.3303062 1:CAS:528:DC%2BD1cXhtlKjsw%3D%3D 17989703
-
RC Schugar P Robbins BM Deasy 2008 Small molecules in stem cell self-renewal and differentiation Gene Ther 15 126 135 10.1038/sj.gt.3303062 1:CAS:528:DC%2BD1cXhtlKjsw%3D%3D 17989703
-
(2008)
Gene Ther
, vol.15
, pp. 126-135
-
-
Schugar, R.C.1
Robbins, P.2
Deasy, B.M.3
|