Hepatitis C virus protein and iron overload induce hepatic steatosis through the unfolded protein response in mice

Liver International

Volumn 30, Issue 5, 2010, Pages 683-692

  Nishina, Sohji ^a,b   Korenaga, Masaaki ^a,b   Hidaka, Isao ^a   Shinozaki, Akane ^a   Sakai, Aya ^a   Gondo, Toshikazu ^c   Tabuchi, Mitsuaki ^b   Kishi, Fumio ^b   Hino, Keisuke ^a,b  

^a YAMAGUCHI UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b KAWASAKI MEDICAL SCHOOL   (Japan)

^c YAMAGUCHI UNIVERSITY HOSPITAL   (Japan)

Author keywords

Endoplasmic reticulum stress; Hepatic steatosis; Hepatitis C virus; Iron; Unfolded protein response

Indexed keywords

ACETYLCYSTEINE; CARNITINE PALMITOYLTRANSFERASE I; CCAAT ENHANCER BINDING PROTEIN; DNA BINDING PROTEIN; FATTY ACID SYNTHASE; FERRITIN; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; GUANINE NUCLEOTIDE EXCHANGE FACTOR; GUANINE NUCLEOTIDE EXCHANGE FACTOR 2ALPHA; HYDROETHIDINE; IRON; POLYPROTEIN; REACTIVE OXYGEN METABOLITE; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; VIRUS PROTEIN; X BOX DNA BINDING PROTEIN 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATOMIC ABSORPTION SPECTROMETRY; AUTOPHAGY; CONTROLLED STUDY; CORRELATION ANALYSIS; DIET SUPPLEMENTATION; DRUG EFFECT; ELECTRON MICROSCOPY; ENDOPLASMIC RETICULUM STRESS; FATTY LIVER; HEPATITIS C VIRUS; IMMUNOBLOTTING; IRON OVERLOAD; LIPID STORAGE; LIVER HISTOLOGY; LIVER LEVEL; MALE; MOUSE; NONHUMAN; PHAGOSOME; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN PHOSPHORYLATION; TRANSGENIC MOUSE;

ANIMALS; AUTOPHAGY; CARNITINE O-PALMITOYLTRANSFERASE; ENDOPLASMIC RETICULUM; FATTY LIVER; HEPATITIS C; IRON OVERLOAD; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; REACTIVE OXYGEN SPECIES; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; TRIGLYCERIDES; UNFOLDED PROTEIN RESPONSE; VIRAL PROTEINS;

EID: 77954367356     PISSN: 14783223     EISSN: 14783231     Source Type: Journal    
DOI: 10.1111/j.1478-3231.2010.02210.x     Document Type: Article

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