Induction of cytochrome P450 2B6 and 3A4 expression by phenobarbital and cyclophosphamide in cultured human liver slices

Pharmaceutical Research

Volumn 20, Issue 4, 2003, Pages 557-568

  Martin, Hélène ^a,b   Sarsat, Jean Pierre ^a   De Waziers, Isabelle ^b   Housset, Chantal ^b   Balladur, Pierre ^b   Beaune, Philippe ^b   Albaladejo, Véronique ^a   Lerche Langrand, Carole ^a  

^a SANOFI   (France)

^b INSERM   (France)

Author keywords

Cyclophosphamide; CYP expression and induction; Human hepatocytes; Human liver slices; Phenobarbital

Indexed keywords

CYCLOPHOSPHAMIDE; CYTOCHROME P450 2B6; CYTOCHROME P450 2C9; CYTOCHROME P450 3A4; PHENOBARBITAL; RPR 5515A; XENOBIOTIC AGENT;

ARTICLE; CELL CULTURE; CELL STRUCTURE; CONTROLLED STUDY; CULTURE MEDIUM; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYME LOCALIZATION; ENZYME SPECIFICITY; HISTOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; LIVER SLICE; PRIORITY JOURNAL; PROTEIN EXPRESSION; TISSUE CULTURE; WESTERN BLOTTING;

EID: 0037392924     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1023234429596     Document Type: Article

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