Regulation of mRNA expression of MDR1, MRP1, MRP2 and MRP3 by prototypical microsomal enzyme inducers in primary cultures of human and rat hepatocytes.

Drug metabolism and pharmacokinetics

Volumn 21, Issue 4, 2006, Pages 297-307

  Nishimura, Masuhiro ^a   Koeda, Akiko ^a   Suzuki, Emako ^a   Kawano, Yuichi ^a   Nakayama, Mitsuo ^a   Satoh, Tetsuo ^a   Narimatsu, Shizuo ^a   Naito, Shinsaku ^a  

^a OTSUKA PHARMACEUTICAL CO LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CARRIER PROTEIN; DEXAMETHASONE; ENZYME INHIBITOR; GLYCOPROTEIN P; MESSENGER RNA; MULTIDRUG RESISTANCE PROTEIN; MULTIDRUG RESISTANCE PROTEIN 1; MULTIDRUG RESISTANCE PROTEIN 2; MULTIDRUG RESISTANCE PROTEIN 3; MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1; MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 2; MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 3; OMEPRAZOLE; RIFAMPICIN;

ANIMAL; ARTICLE; CELL CULTURE; DRUG EFFECT; ENZYME INDUCTION; ENZYMOLOGY; FEMALE; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; HUMAN; LIVER CELL; METABOLISM; MICROSOME; RAT; SPRAGUE DAWLEY RAT;

ANIMALS; CELLS, CULTURED; DEXAMETHASONE; ENZYME INDUCTION; ENZYME INHIBITORS; FEMALE; GENE EXPRESSION REGULATION; HEPATOCYTES; HUMANS; MEMBRANE TRANSPORT PROTEINS; MICROSOMES; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; OMEPRAZOLE; P-GLYCOPROTEIN; RATS; RATS, SPRAGUE-DAWLEY; RIFAMPIN; RNA, MESSENGER; TRANSCRIPTION, GENETIC;

EID: 35648962332     PISSN: 13474367     EISSN: None     Source Type: Journal    
DOI: 10.2133/dmpk.21.297     Document Type: Article

References (0)