Induction of metabolism and transport in human intestine: Validation of precision-cut slices as a tool to study induction of drug metabolism in human intestine in vitro

Drug Metabolism and Disposition

Volumn 36, Issue 3, 2008, Pages 604-613

  Van De Kerkhof, Esther G ^a   De Graaf, Inge A M ^a   Ungell, Anna Lena B ^b   Groothuis, Geny M M ^a,c  

^a UNIVERSITY OF GRONINGEN   (Netherlands)

^b ASTRAZENECA R AND D   (Sweden)

^c Department of Pharmacokinetics and Drug Delivery ^*  (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

BETA NAPHTHOFLAVONE; CYTOCHROME P450 1A1; CYTOCHROME P450 2B6; CYTOCHROME P450 3A4; DEXAMETHASONE; GLUCURONOSYLTRANSFERASE 1A6; GLYCOPROTEIN P; PHENOBARBITAL; QUERCETIN;

ACCURACY; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME METABOLISM; HUMAN; HUMAN TISSUE; IN VITRO STUDY; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL;

ADENOSINE TRIPHOSPHATE; COLON; CYTOCHROME P-450 CYP1A1; CYTOCHROME P-450 CYP3A; HUMANS; JEJUNUM; MICROTOMY; PHARMACEUTICAL PREPARATIONS; REPRODUCIBILITY OF RESULTS; RNA, MESSENGER;

EID: 40849104960     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.107.018820     Document Type: Article

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