Synthesis of bis-1,2,3-triazolo-bridged unsymmetrical pyrrolobenzodiazepine trimers via 'click' chemistry and their DNA-binding studies

Tetrahedron

Volumn 66, Issue 29, 2010, Pages 5498-5506

  Kamal, Ahmed ^a   Shankaraiah, Nagula ^b   Reddy, Ch Ratna ^a   Prabhakar, S ^a   Markandeya, Nagula ^a   Srivastava, Hemant Kumar ^a   Sastry, G Narahari ^a  

^a INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

^b NATIONAL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH NIPER   (India)

Author keywords

1,2,3 Triazoles; Click chemistry; Cycloadditions; DNA binding affinity; Molecular modeling; Pyrrolobenzodiazepine trimers

Indexed keywords

1,2,3 TRIAZOLO PYRROLO[2,1 C][1,4]BENZODIAZEPINE TRIMER; BENZODIAZEPINE DERIVATIVE; NITROGEN; UNCLASSIFIED DRUG;

ARTICLE; DENATURATION; DNA BINDING; MOLECULAR MODEL; PRIORITY JOURNAL; SYNTHESIS;

EID: 77954315033     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2010.05.003     Document Type: Article

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