-
2
-
-
0025727771
-
Novel zinc finger gene implicated as myc collaborator by retrovirally accelerated lymphomagenesis in E mu-myc transgenic mice
-
Haupt Y, Alexander WS, Barri G, Klinken SP, Adams JM. Novel zinc finger gene implicated as myc collaborator by retrovirally accelerated lymphomagenesis in E mu-myc transgenic mice. Cell 1991;65:753-63.
-
(1991)
Cell
, vol.65
, pp. 753-763
-
-
Haupt, Y.1
Alexander, W.S.2
Barri, G.3
Klinken, S.P.4
Adams, J.M.5
-
3
-
-
0038349957
-
Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells
-
Park IK, Qian D, Kiel M, et al. Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells. Nature 2003;423:302-5.
-
(2003)
Nature
, vol.423
, pp. 302-305
-
-
Park, I.K.1
Qian, D.2
Kiel, M.3
-
4
-
-
0037673984
-
Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells
-
Lessard J, Sauvageau G. Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells. Nature 2003;423:255-60.
-
(2003)
Nature
, vol.423
, pp. 255-260
-
-
Lessard, J.1
Sauvageau, G.2
-
5
-
-
0242667922
-
Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation
-
Molofsky AV, Pardal R, Iwashita T, Park IK, Clarke MF, Morrison SJ. Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation. Nature 2003;425:962-7.
-
(2003)
Nature
, vol.425
, pp. 962-967
-
-
Molofsky, A.V.1
Pardal, R.2
Iwashita, T.3
Park, I.K.4
Clarke, M.F.5
Morrison, S.J.6
-
6
-
-
34247891673
-
Bmi-1 is essential for the tumorigenicity of neuroblastoma cells
-
Cui H, Hu B, Li T, et al. Bmi-1 is essential for the tumorigenicity of neuroblastoma cells. Am J Pathol 2007;170:1370-8.
-
(2007)
Am J Pathol
, vol.170
, pp. 1370-1378
-
-
Cui, H.1
Hu, B.2
Li, T.3
-
7
-
-
0037102196
-
The Bmi-1 oncogene induces telomerase activity and immortalizes human mammary epithelial cells
-
Dimri GP, Martinez JL, Jacobs JJ, et al. The Bmi-1 oncogene induces telomerase activity and immortalizes human mammary epithelial cells. Cancer Res 2002; 62:4736-45.
-
(2002)
Cancer Res
, vol.62
, pp. 4736-4745
-
-
Dimri, G.P.1
Martinez, J.L.2
Jacobs, J.J.3
-
8
-
-
1342289563
-
Bmi1, stem cells, and senescence regulation
-
Park IK, Morrison SJ, Clarke MF. Bmi1, stem cells, and senescence regulation. J Clin Invest 2004;113:175-9.
-
(2004)
J Clin Invest
, vol.113
, pp. 175-179
-
-
Park, I.K.1
Morrison, S.J.2
Clarke, M.F.3
-
10
-
-
1642633053
-
Bmi1 is essential for cerebellar development and is overexpressed in human medulloblastomas
-
Leung C, Lingbeek M, Shakhova O, et al. Bmi1 is essential for cerebellar development and is overexpressed in human medulloblastomas. Nature 2004;428: 337-41.
-
(2004)
Nature
, vol.428
, pp. 337-341
-
-
Leung, C.1
Lingbeek, M.2
Shakhova, O.3
-
11
-
-
0035906853
-
The bmi-1 oncoprotein is differentially expressed in non-small cell lung cancer and correlates with INK4A-ARF locus expression
-
Vonlanthen S, Heighway J, Altermatt HJ, et al. The bmi-1 oncoprotein is differentially expressed in non-small cell lung cancer and correlates with INK4A-ARF locus expression. Br J Cancer 2001;84:1372-6.
-
(2001)
Br J Cancer
, vol.84
, pp. 1372-1376
-
-
Vonlanthen, S.1
Heighway, J.2
Altermatt, H.J.3
-
12
-
-
0346094301
-
The Bmi-1 oncoprotein is overexpressed in human colorectal cancer and correlates with the reduced p16INK4a/p14ARF proteins
-
Kim JH, Yoon SY, Kim CN, et al. The Bmi-1 oncoprotein is overexpressed in human colorectal cancer and correlates with the reduced p16INK4a/p14ARF proteins. Cancer Lett 2004;203:217-24.
-
(2004)
Cancer Lett
, vol.203
, pp. 217-224
-
-
Kim, J.H.1
Yoon, S.Y.2
Kim, C.N.3
-
13
-
-
34548663637
-
Consistent expression of the stem cell renewal factor BMI-1 in primary and metastatic melanoma
-
Mihic-Probst D, Kuster A, Kilgus S, et al. Consistent expression of the stem cell renewal factor BMI-1 in primary and metastatic melanoma. Int J Cancer 2007;121:1764-70.
-
(2007)
Int J Cancer
, vol.121
, pp. 1764-1770
-
-
Mihic-Probst, D.1
Kuster, A.2
Kilgus, S.3
-
14
-
-
0035154779
-
Treatment of B-cell non-Hodgkin's lymphoma with anti CD 20 monoclonal antibody Rituximab
-
Sacchi S, Federico M, Dastoli G, et al. Treatment of B-cell non-Hodgkin's lymphoma with anti CD 20 monoclonal antibody Rituximab. Crit Rev Oncol Hematol 2001;37:13-25.
-
(2001)
Crit Rev Oncol Hematol
, vol.37
, pp. 13-25
-
-
Sacchi, S.1
Federico, M.2
Dastoli, G.3
-
15
-
-
41049109184
-
Increased polycomb-group oncogene Bmi-1 expression correlates with poor prognosis in hepatocellular carcinoma
-
Wang H, Pan K, Zhang HK, et al. Increased polycomb-group oncogene Bmi-1 expression correlates with poor prognosis in hepatocellular carcinoma. J Cancer Res Clin Oncol 2008;134:535-41.
-
(2008)
J Cancer Res Clin Oncol
, vol.134
, pp. 535-541
-
-
Wang, H.1
Pan, K.2
Zhang, H.K.3
-
16
-
-
48749104292
-
The overexpression of polycomb group proteins Bmi1 and EZH2 is associated with the progression and aggressive biological behavior of hepatocellular carcinoma
-
Sasaki M, Ikeda H, Itatsu K, et al. The overexpression of polycomb group proteins Bmi1 and EZH2 is associated with the progression and aggressive biological behavior of hepatocellular carcinoma. Lab Invest 2008.
-
(2008)
Lab Invest
-
-
Sasaki, M.1
Ikeda, H.2
Itatsu, K.3
-
17
-
-
54249132606
-
The polycomb gene product BMI1 contributes to the maintenance of tumor-initiating side population cells in hepatocellular carcinoma
-
Chiba T, Miyagi S, Saraya A, et al. The polycomb gene product BMI1 contributes to the maintenance of tumor-initiating side population cells in hepatocellular carcinoma. Cancer Res 2008;68:7742-9.
-
(2008)
Cancer Res
, vol.68
, pp. 7742-7749
-
-
Chiba, T.1
Miyagi, S.2
Saraya, A.3
-
18
-
-
33745924696
-
Side population purified from hepatocellular carcinoma cells harbors cancer stem cell-like properties
-
Chiba T, Kita K, Zheng YW, et al. Side population purified from hepatocellular carcinoma cells harbors cancer stem cell-like properties. Hepatology 2006; 44:240-51.
-
(2006)
Hepatology
, vol.44
, pp. 240-251
-
-
Chiba, T.1
Kita, K.2
Zheng, Y.W.3
-
19
-
-
0035985214
-
-
Chen X, Cheung ST, So S, et al. Gene expression patterns in human liver cancers. Mol Biol Cell 2002;13:1929-39.
-
Chen X, Cheung ST, So S, et al. Gene expression patterns in human liver cancers. Mol Biol Cell 2002;13:1929-39.
-
-
-
-
20
-
-
27944491603
-
Array-based comparative genomic hybridization reveals recurrent chromosomal aberrations and Jab1 as a potential target for 8q gain in hepatocellular carcinoma
-
Patil MA, Gutgemann I, Zhang J, et al. Array-based comparative genomic hybridization reveals recurrent chromosomal aberrations and Jab1 as a potential target for 8q gain in hepatocellular carcinoma. Carcinogenesis 2005;26:2050-7.
-
(2005)
Carcinogenesis
, vol.26
, pp. 2050-2057
-
-
Patil, M.A.1
Gutgemann, I.2
Zhang, J.3
-
21
-
-
20444475795
-
An integrated data analysis approach to characterize genes highly expressed in hepatocellular carcinoma
-
Patil MA, Chua MS, Pan KH, et al. An integrated data analysis approach to characterize genes highly expressed in hepatocellular carcinoma. Oncogene 2005; 24:3737-47.
-
(2005)
Oncogene
, vol.24
, pp. 3737-3747
-
-
Patil, M.A.1
Chua, M.S.2
Pan, K.H.3
-
22
-
-
0035985177
-
Identification of genes periodically expressed in the human cell cycle and their expression in tumors
-
Whitfield ML, Sherlock G, Saldanha AJ, et al. Identification of genes periodically expressed in the human cell cycle and their expression in tumors. Mol Biol Cell 2002;13:1977-2000.
-
(2002)
Mol Biol Cell
, vol.13
, pp. 1977-2000
-
-
Whitfield, M.L.1
Sherlock, G.2
Saldanha, A.J.3
-
23
-
-
33746459740
-
Stem cell self-renewal and cancer cell proliferation are regulated by common networks that balance the activation of proto-oncogenes and tumor suppressors
-
Pardal R, Molofsky AV, He S, Morrison SJ. Stem cell self-renewal and cancer cell proliferation are regulated by common networks that balance the activation of proto-oncogenes and tumor suppressors. Cold Spring Harbor Symp Quant Biol 2005;70:177-85.
-
(2005)
Cold Spring Harbor Symp Quant Biol
, vol.70
, pp. 177-185
-
-
Pardal, R.1
Molofsky, A.V.2
He, S.3
Morrison, S.J.4
-
24
-
-
0033552813
-
The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus
-
Jacobs JJ, Kieboom K, Marino S, DePinho RA, van Lohuizen M. The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus. Nature 1999;397:164-8.
-
(1999)
Nature
, vol.397
, pp. 164-168
-
-
Jacobs, J.J.1
Kieboom, K.2
Marino, S.3
DePinho, R.A.4
van Lohuizen, M.5
-
25
-
-
35948990017
-
Bmi-1 cooperates with H-Ras to transform human mammary epithelial cells via dysregulation of multiple growthregulatory pathways
-
Datta S, Hoenerhoff MJ, Bommi P, et al. Bmi-1 cooperates with H-Ras to transform human mammary epithelial cells via dysregulation of multiple growthregulatory pathways. Cancer Res 2007;67:10286-95.
-
(2007)
Cancer Res
, vol.67
, pp. 10286-10295
-
-
Datta, S.1
Hoenerhoff, M.J.2
Bommi, P.3
-
26
-
-
33645976174
-
Ubiquitous activation of Ras and Jak/Stat pathways in human HCC
-
Calvisi DF, Ladu S, Gorden A, et al. Ubiquitous activation of Ras and Jak/Stat pathways in human HCC. Gastroenterology 2006;130:1117-28.
-
(2006)
Gastroenterology
, vol.130
, pp. 1117-1128
-
-
Calvisi, D.F.1
Ladu, S.2
Gorden, A.3
-
27
-
-
1642535593
-
Hepatocarcinogenesis in mice with β-catenin and Ha-ras gene mutations
-
Harada N, Oshima H, Katoh M, Tamai Y, Oshima M, Taketo MM. Hepatocarcinogenesis in mice with β-catenin and Ha-ras gene mutations. Cancer Res 2004;64:48-54.
-
(2004)
Cancer Res
, vol.64
, pp. 48-54
-
-
Harada, N.1
Oshima, H.2
Katoh, M.3
Tamai, Y.4
Oshima, M.5
Taketo, M.M.6
-
28
-
-
42249098060
-
Integration of genomic analysis and in vivo transfection to identify sprouty 2 as a candidate tumor suppressor in liver cancer
-
Lee SA, Ho C, Roy R, et al. Integration of genomic analysis and in vivo transfection to identify sprouty 2 as a candidate tumor suppressor in liver cancer. Hepatology 2008;47:1200-10.
-
(2008)
Hepatology
, vol.47
, pp. 1200-1210
-
-
Lee, S.A.1
Ho, C.2
Roy, R.3
-
29
-
-
4344665192
-
Disregulation of E-cadherin in transgenic mouse models of liver cancer
-
Calvisi DF, Ladu S, Conner EA, Factor VM, Thorgeirsson SS. Disregulation of E-cadherin in transgenic mouse models of liver cancer. Lab Invest 2004;84: 1137-47.
-
(2004)
Lab Invest
, vol.84
, pp. 1137-1147
-
-
Calvisi, D.F.1
Ladu, S.2
Conner, E.A.3
Factor, V.M.4
Thorgeirsson, S.S.5
-
30
-
-
0036725378
-
Altered expression of E-cadherin in hepatocellular carcinoma: Correlations with genetic alterations, β-catenin expression, and clinical features
-
Wei Y, Van Nhieu JT, Prigent S, Srivatanakul P, Tiollais P, Buendia MA. Altered expression of E-cadherin in hepatocellular carcinoma: correlations with genetic alterations, β-catenin expression, and clinical features. Hepatology 2002; 36:692-701.
-
(2002)
Hepatology
, vol.36
, pp. 692-701
-
-
Wei, Y.1
Van Nhieu, J.T.2
Prigent, S.3
Srivatanakul, P.4
Tiollais, P.5
Buendia, M.A.6
-
31
-
-
4744347276
-
Novel endothelial cell markers in hepatocellular carcinoma
-
Chen X, Higgins J, Cheung ST, et al. Novel endothelial cell markers in hepatocellular carcinoma. Mod Pathol 2004.
-
(2004)
Mod Pathol
-
-
Chen, X.1
Higgins, J.2
Cheung, S.T.3
-
32
-
-
17744404952
-
Adenovirus-mediated Cre deletion of floxed sequences in primary mouse cells is an efficient alternative for studies of gene deletion
-
Prost S, Sheahan S, Rannie D, Harrison DJ. Adenovirus-mediated Cre deletion of floxed sequences in primary mouse cells is an efficient alternative for studies of gene deletion. Nucleic Acids Res 2001;29:E80.
-
(2001)
Nucleic Acids Res
, vol.29
-
-
Prost, S.1
Sheahan, S.2
Rannie, D.3
Harrison, D.J.4
-
33
-
-
0030944985
-
Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a
-
Serrano M, Lin AW, McCurrach ME, Beach D, Lowe SW. Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a. Cell 1997;88:593-602.
-
(1997)
Cell
, vol.88
, pp. 593-602
-
-
Serrano, M.1
Lin, A.W.2
McCurrach, M.E.3
Beach, D.4
Lowe, S.W.5
-
34
-
-
0032190629
-
Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling
-
Lin AW, Barradas M, Stone JC, van Aelst L, Serrano M, Lowe SW. Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling. Genes Dev 1998;12:3008-19.
-
(1998)
Genes Dev
, vol.12
, pp. 3008-3019
-
-
Lin, A.W.1
Barradas, M.2
Stone, J.C.3
van Aelst, L.4
Serrano, M.5
Lowe, S.W.6
-
35
-
-
53049085085
-
BMI-1 promotes ewing sarcoma tumorigenicity independent of CDKN2A repression
-
Douglas D, Hsu JH, Hung L, et al. BMI-1 promotes ewing sarcoma tumorigenicity independent of CDKN2A repression. Cancer Res 2008;68:6507-15.
-
(2008)
Cancer Res
, vol.68
, pp. 6507-6515
-
-
Douglas, D.1
Hsu, J.H.2
Hung, L.3
-
36
-
-
34648826957
-
Antisense RNA-mediated suppression of Bmi-1 gene expression inhibits the proliferation of lung cancer cell line A549
-
Yu Q, Su B, Liu D, et al. Antisense RNA-mediated suppression of Bmi-1 gene expression inhibits the proliferation of lung cancer cell line A549. Oligonucleotides 2007;17:327-35.
-
(2007)
Oligonucleotides
, vol.17
, pp. 327-335
-
-
Yu, Q.1
Su, B.2
Liu, D.3
-
37
-
-
34347354307
-
Contribution of polycomb homologues Bmi-1 and Mel-18 to medulloblastoma pathogenesis
-
Wiederschain D, Chen L, Johnson B, et al. Contribution of polycomb homologues Bmi-1 and Mel-18 to medulloblastoma pathogenesis. Mol Cell Biol 2007; 27:4968-79.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 4968-4979
-
-
Wiederschain, D.1
Chen, L.2
Johnson, B.3
-
38
-
-
37049014475
-
Expression of Bmi-1 in epidermis enhances cell survival by altering cell cycle regulatory protein expression and inhibiting apoptosis
-
Lee K, Adhikary G, Balasubramanian S, et al. Expression of Bmi-1 in epidermis enhances cell survival by altering cell cycle regulatory protein expression and inhibiting apoptosis. J Invest Dermatol 2008;128:9-17.
-
(2008)
J Invest Dermatol
, vol.128
, pp. 9-17
-
-
Lee, K.1
Adhikary, G.2
Balasubramanian, S.3
-
39
-
-
55049115359
-
Bmi1 promotes prostate tumorigenesis via inhibiting p16(INK4A) and p14(ARF) expression
-
Fan C, He L, Kapoor A, et al. Bmi1 promotes prostate tumorigenesis via inhibiting p16(INK4A) and p14(ARF) expression. Biochim Biophys Acta 2008;1782:642-8.
-
(2008)
Biochim Biophys Acta
, vol.1782
, pp. 642-648
-
-
Fan, C.1
He, L.2
Kapoor, A.3
-
40
-
-
50149092414
-
Bmi1 is critical for lung tumorigenesis and bronchioalveolar stem cell expansion
-
Dovey JS, Zacharek SJ, Kim CF, Lees JA. Bmi1 is critical for lung tumorigenesis and bronchioalveolar stem cell expansion. Proc Natl Acad Sci U S A 2008;105:11857-62.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 11857-11862
-
-
Dovey, J.S.1
Zacharek, S.J.2
Kim, C.F.3
Lees, J.A.4
-
41
-
-
0024801490
-
Low incidence of point mutation of c-Ki-ras and N-ras oncogenes in human hepatocellular carcinoma
-
Tsuda H, Hirohashi S, Shimosato Y, Ino Y, Yoshida T, Terada M. Low incidence of point mutation of c-Ki-ras and N-ras oncogenes in human hepatocellular carcinoma. Jpn J Cancer Res 1989;80:196-9.
-
(1989)
Jpn J Cancer Res
, vol.80
, pp. 196-199
-
-
Tsuda, H.1
Hirohashi, S.2
Shimosato, Y.3
Ino, Y.4
Yoshida, T.5
Terada, M.6
-
42
-
-
0026553679
-
Infrequent point mutations in codons 12 and 61 of ras oncogenes in human hepatocellular carcinomas
-
Challen C, Guo K, Collier JD, Cavanagh D, Bassendine MF. Infrequent point mutations in codons 12 and 61 of ras oncogenes in human hepatocellular carcinomas. J Hepatol 1992;14:342-6.
-
(1992)
J Hepatol
, vol.14
, pp. 342-346
-
-
Challen, C.1
Guo, K.2
Collier, J.D.3
Cavanagh, D.4
Bassendine, M.F.5
-
43
-
-
35148840173
-
Bmi1 controls tumor development in an Ink4a/Arf-independent manner in a mouse model for glioma
-
Bruggeman SW, Hulsman D, Tanger E, et al. Bmi1 controls tumor development in an Ink4a/Arf-independent manner in a mouse model for glioma. Cancer Cell 2007;12:328-41.
-
(2007)
Cancer Cell
, vol.12
, pp. 328-341
-
-
Bruggeman, S.W.1
Hulsman, D.2
Tanger, E.3
-
44
-
-
67349156082
-
-
Liu J, Cao L, Chen J, et al. Bmi1 regulates mitochondrial function and the DNA damage response pathway. Nature 2009.
-
Liu J, Cao L, Chen J, et al. Bmi1 regulates mitochondrial function and the DNA damage response pathway. Nature 2009.
-
-
-
-
45
-
-
35548966020
-
-
Tward AD, Jones KD, Yant S, et al. Distinct pathways of genomic progression to benign and malignant tumors of the liver. Proc Natl Acad Sci U S A 2007.
-
Tward AD, Jones KD, Yant S, et al. Distinct pathways of genomic progression to benign and malignant tumors of the liver. Proc Natl Acad Sci U S A 2007.
-
-
-
-
46
-
-
34249112157
-
BrdU assay for neurogenesis in rodents
-
Wojtowicz JM, Kee N. BrdU assay for neurogenesis in rodents. Nat Protoc 2006;1:1399-405.
-
(2006)
Nat Protoc
, vol.1
, pp. 1399-1405
-
-
Wojtowicz, J.M.1
Kee, N.2
-
47
-
-
0037423288
-
Evidence that cyclin D1 mediates both growth and proliferation downstream of TOR in hepatocytes
-
Nelsen CJ, Rickheim DG, Tucker MM, Hansen LK, Albrecht JH. Evidence that cyclin D1 mediates both growth and proliferation downstream of TOR in hepatocytes. J Biol Chem 2003;278:3656-63.
-
(2003)
J Biol Chem
, vol.278
, pp. 3656-3663
-
-
Nelsen, C.J.1
Rickheim, D.G.2
Tucker, M.M.3
Hansen, L.K.4
Albrecht, J.H.5
-
48
-
-
0037340013
-
Ras stimulates aberrant cell cycle progression and apoptosis in rat thyroid cells
-
Cheng G, Lewis AE, Meinkoth JL. Ras stimulates aberrant cell cycle progression and apoptosis in rat thyroid cells. Mol Endocrinol 2003;17:450-9.
-
(2003)
Mol Endocrinol
, vol.17
, pp. 450-459
-
-
Cheng, G.1
Lewis, A.E.2
Meinkoth, J.L.3
|