-
1
-
-
3242754448
-
Acute myeloid leukemia originates from a hierarchy of leukemic stem cell classes that differ in self-renewal capacity
-
Hope KJ, Jin L, Dick JE. Acute myeloid leukemia originates from a hierarchy of leukemic stem cell classes that differ in self-renewal capacity. Nat Immunol 2004; 5: 738-743.
-
(2004)
Nat. Immunol.
, vol.5
, pp. 738-743
-
-
Hope, K.J.1
Jin, L.2
Dick, J.E.3
-
3
-
-
6044229354
-
Concepts of human leukemic development
-
Warner JK, Wang JC, Hope KJ, Jin L, Dick JE. Concepts of human leukemic development. Oncogene 2004; 23: 7164-7177.
-
(2004)
Oncogene
, vol.23
, pp. 7164-7177
-
-
Warner, J.K.1
Wang, J.C.2
Hope, K.J.3
Jin, L.4
Dick, J.E.5
-
4
-
-
0037079003
-
Rules for making human tumor cells
-
Hahn WC, Weinberg RA. Rules for making human tumor cells. N Engl J Med 2002; 347: 1593-1603.
-
(2002)
N. Engl. J. Med.
, vol.347
, pp. 1593-1603
-
-
Hahn, W.C.1
Weinberg, R.A.2
-
5
-
-
0027434620
-
E2A-Pbx1, the t(1;19) translocation protein of human pre-B-cell acute lymphocytic leukemia, causes acute myeloid leukemia in mice
-
Kamps MP, Baltimore D. E2A-Pbx1, the t(1;19) translocation protein of human pre-B-cell acute lymphocytic leukemia, causes acute myeloid leukemia in mice. Mol Cell Biol 1993; 13: 351-357.
-
(1993)
Mol. Cell Biol.
, vol.13
, pp. 351-357
-
-
Kamps, M.P.1
Baltimore, D.2
-
6
-
-
1642580761
-
E2a/Pbx1 induces the rapid proliferation of stem cell factor-dependent murine pro-T cells that cause acute T-lymphoid or myeloid leukemias in mice
-
Sykes DB, Kamps MP. E2a/Pbx1 induces the rapid proliferation of stem cell factor-dependent murine pro-T cells that cause acute T-lymphoid or myeloid leukemias in mice. Mol Cell Biol 2004; 24: 1256-1269.
-
(2004)
Mol. Cell Biol.
, vol.24
, pp. 1256-1269
-
-
Sykes, D.B.1
Kamps, M.P.2
-
7
-
-
1642276757
-
A dominant-negative mutant of C/EBPalpha, associated with acute myeloid leukemias, inhibits differentiation of myeloid and erythroid progenitors of man but not mouse
-
Schwieger M, Lohler J, Fischer M, Herwig U, Tenen DG, Stocking C. A dominant-negative mutant of C/EBPalpha, associated with acute myeloid leukemias, inhibits differentiation of myeloid and erythroid progenitors of man but not mouse. Blood 2004; 103: 2744-2752.
-
(2004)
Blood
, vol.103
, pp. 2744-2752
-
-
Schwieger, M.1
Lohler, J.2
Fischer, M.3
Herwig, U.4
Tenen, D.G.5
Stocking, C.6
-
8
-
-
0020520516
-
Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes
-
Land H, Parada LF, Weinberg RA. Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes. Nature 1983; 304: 596-602.
-
(1983)
Nature
, vol.304
, pp. 596-602
-
-
Land, H.1
Parada, L.F.2
Weinberg, R.A.3
-
9
-
-
0020520517
-
Adenovirus early region 1A enables viral and cellular transforming genes to transform primary cells in culture
-
Ruley HE. Adenovirus early region 1A enables viral and cellular transforming genes to transform primary cells in culture. Nature 1983; 304: 602-606.
-
(1983)
Nature
, vol.304
, pp. 602-606
-
-
Ruley, H.E.1
-
10
-
-
0037102561
-
Distinct requirements for Ras oncogenesis in human versus mouse cells
-
Hamad NM, Elconin JH, Karnoub AE, Bai W, Rich JN, Abraham RT et al. Distinct requirements for Ras oncogenesis in human versus mouse cells. Genes Dev 2002; 16: 2045-2057.
-
(2002)
Genes Dev.
, vol.16
, pp. 2045-2057
-
-
Hamad, N.M.1
Elconin, J.H.2
Karnoub, A.E.3
Bai, W.4
Rich, J.N.5
Abraham, R.T.6
-
11
-
-
0034663431
-
PML/RAR alpha fusion protein expression in normal human hematopoietic progenitors dictates myeloid commitment and the promyelocytic phenotype
-
Grignani F, Valtieri M, Gabbianelli M, Gelmetti V, Botta R, Luchetti L et al. PML/RAR alpha fusion protein expression in normal human hematopoietic progenitors dictates myeloid commitment and the promyelocytic phenotype. Blood 2000; 96: 1531-1537.
-
(2000)
Blood
, vol.96
, pp. 1531-1537
-
-
Grignani, F.1
Valtieri, M.2
Gabbianelli, M.3
Gelmetti, V.4
Botta, R.5
Luchetti, L.6
-
12
-
-
0030931603
-
Cell death induction by the acute promyelocytic leukemia-specific PML/RARalpha fusion protein
-
Ferrucci PF, Grignani F, Pearson M, Fagioli M, Nicoletti I, Pelicci PG. Cell death induction by the acute promyelocytic leukemia-specific PML/ RARalpha fusion protein. Proc Natl Acad Sci USA 1997; 94: 10901-10906.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 10901-10906
-
-
Ferrucci, P.F.1
Grignani, F.2
Pearson, M.3
Fagioli, M.4
Nicoletti, I.5
Pelicci, P.G.6
-
13
-
-
0028091194
-
A cell initiating human acute myeloid leukemia after transplantation into SCID mice
-
Lapidot T, Sirard C, Vormoor J, Murdoch B, Hoang T, Caceres-Cortes J et al. A cell initiating human acute myeloid leukemia after transplantation into SCID mice. Nature 1994; 367: 645-648.
-
(1994)
Nature
, vol.367
, pp. 645-648
-
-
Lapidot, T.1
Sirard, C.2
Vormoor, J.3
Murdoch, B.4
Hoang, T.5
Caceres-Cortes, J.6
-
14
-
-
0030789242
-
Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell
-
Bonnet D, Dick JE. Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nat Med 1997; 3: 730-737.
-
(1997)
Nat. Med.
, vol.3
, pp. 730-737
-
-
Bonnet, D.1
Dick, J.E.2
-
15
-
-
0345167904
-
Maintaining the self-renewal and differentiation potential of human CD34+ hematopoietic cells using a single genetic element
-
Mulloy JC, Cammenga J, Berguido FJ, Wu K, Zhou P, Comenzo RL et al. Maintaining the self-renewal and differentiation potential of human CD34+ hematopoietic cells using a single genetic element. Blood 2003; 102: 4369-4376.
-
(2003)
Blood
, vol.102
, pp. 4369-4376
-
-
Mulloy, J.C.1
Cammenga, J.2
Berguido, F.J.3
Wu, K.4
Zhou, P.5
Comenzo, R.L.6
-
16
-
-
0036682496
-
Deregulated expression of HOXB4 enhances the primitive growth activity of human hematopoietic cells
-
Buske C, Feuring-Buske M, Abramovich C, Spiekermann K, Eaves CJ, Coulombel L et al. Deregulated expression of HOXB4 enhances the primitive growth activity of human hematopoietic cells. Blood 2002; 100: 862-868.
-
(2002)
Blood
, vol.100
, pp. 862-868
-
-
Buske, C.1
Feuring-Buske, M.2
Abramovich, C.3
Spiekermann, K.4
Eaves, C.J.5
Coulombel, L.6
-
17
-
-
0033120706
-
Seed versus soil: The importance of the target cell for transgenic models of human leukemias
-
Westervelt P, Ley TJ. Seed versus soil: The importance of the target cell for transgenic models of human leukemias. Blood 1999; 93: 2143-2148.
-
(1999)
Blood
, vol.93
, pp. 2143-2148
-
-
Westervelt, P.1
Ley, T.J.2
-
18
-
-
0032878921
-
The fusion gene Cbfb-MYH11 blocks myeloid differentiation and predisposes mice to acute myelomonocytic leukaemia
-
Castilla LH, Garrett L, Adya N, Orlic D, Dutra A, Anderson S et al. The fusion gene Cbfb-MYH11 blocks myeloid differentiation and predisposes mice to acute myelomonocytic leukaemia. Nat Genet 1999; 23: 144-146.
-
(1999)
Nat. Genet.
, vol.23
, pp. 144-146
-
-
Castilla, L.H.1
Garrett, L.2
Adya, N.3
Orlic, D.4
Dutra, A.5
Anderson, S.6
-
19
-
-
17944376561
-
AML1-ETO expression is directly involved in the development of acute myeloid leukemia in the presence of additional mutations
-
Yuan Y, Zhou L, Miyamoto T, Iwasaki H, Harakawa N, Hetherington CJ et al. AML1-ETO expression is directly involved in the development of acute myeloid leukemia in the presence of additional mutations. Proc Natl Acad Sci USA 2001; 98: 10398-10403.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 10398-10403
-
-
Yuan, Y.1
Zhou, L.2
Miyamoto, T.3
Iwasaki, H.4
Harakawa, N.5
Hetherington, C.J.6
-
20
-
-
0028881069
-
Acute non-lymphoblastic leukaemia with t(16;21): Case report with a review of the literature
-
Hiyoshi M, Koh KR, Yamane T, Tatsumi N. Acute non-lymphoblastic leukaemia with t(16;21): Case report with a review of the literature. Clin Lab Haematol 1995; 17: 243-246.
-
(1995)
Clin. Lab. Haematol.
, vol.17
, pp. 243-246
-
-
Hiyoshi, M.1
Koh, K.R.2
Yamane, T.3
Tatsumi, N.4
-
21
-
-
0030871371
-
Consistent detection of TLS/FUS-ERG chimeric transcripts in acute myeloid leukemia with t(16;21)(p11;q22) and identification of a novel transcript
-
Kong XT, Ida K, Ichikawa H, Shimizu K, Ohki M, Maseki N et al. Consistent detection of TLS/FUS-ERG chimeric transcripts in acute myeloid leukemia with t(16;21)(p11;q22) and identification of a novel transcript. Blood 1997; 90: 1192-1199.
-
(1997)
Blood
, vol.90
, pp. 1192-1199
-
-
Kong, X.T.1
Ida, K.2
Ichikawa, H.3
Shimizu, K.4
Ohki, M.5
Maseki, N.6
-
22
-
-
0032493377
-
Retroviral transduction of TLS-ERG initiates a leukemogenic program in normal human hematopoietic cells
-
Pereira DS, Dorrell C, Ito CY, Gan OI, Murdoch B, Rao VN et al. Retroviral transduction of TLS-ERG initiates a leukemogenic program in normal human hematopoietic cells. Proc Natl Acad Sci USA 1998; 95: 8239-8244.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 8239-8244
-
-
Pereira, D.S.1
Dorrell, C.2
Ito, C.Y.3
Gan, O.I.4
Murdoch, B.5
Rao, V.N.6
-
23
-
-
16144365969
-
Identification of primitive human hematopoietic cells capable of repopulating NOD/SCID mouse bone marrow: Implications for gene therapy
-
Larochelle A, Vormoor J, Hanenberg H, Wang JC, Bhatia M, Lapidot T et al. Identification of primitive human hematopoietic cells capable of repopulating NOD/SCID mouse bone marrow: Implications for gene therapy. Nat Med 1996; 2: 1329-1337.
-
(1996)
Nat. Med.
, vol.2
, pp. 1329-1337
-
-
Larochelle, A.1
Vormoor, J.2
Hanenberg, H.3
Wang, J.C.4
Bhatia, M.5
Lapidot, T.6
-
24
-
-
0035228050
-
Distinct classes of human stem cells that differ in proliferative and self-renewal potential
-
Guenechea G, Gan OI, Dorrell C, Dick JE. Distinct classes of human stem cells that differ in proliferative and self-renewal potential. Nat Immunol 2001; 2: 75-82.
-
(2001)
Nat. Immunol.
, vol.2
, pp. 75-82
-
-
Guenechea, G.1
Gan, O.I.2
Dorrell, C.3
Dick, J.E.4
-
25
-
-
0030668722
-
Human telomerase contains evolutionarily conserved catalytic and structural subunits
-
Harrington L, Zhou W, McPhail T, Oulton R, Yeung DS, Mar V et al. Human telomerase contains evolutionarily conserved catalytic and structural subunits. Genes Dev 1997; 11: 3109-3115.
-
(1997)
Genes Dev.
, vol.11
, pp. 3109-3115
-
-
Harrington, L.1
Zhou, W.2
McPhail, T.3
Oulton, R.4
Yeung, D.S.5
Mar, V.6
-
26
-
-
0034040751
-
Gene transfer by lentiviral vectors is limited by nuclear translocation and rescued by HIV-1 pol sequences
-
Follenzi A, Ailles LE, Bakovic S, Geuna M, Naldini L. Gene transfer by lentiviral vectors is limited by nuclear translocation and rescued by HIV-1 pol sequences. Nat Genet 2000; 25: 217-222.
-
(2000)
Nat. Genet.
, vol.25
, pp. 217-222
-
-
Follenzi, A.1
Ailles, L.E.2
Bakovic, S.3
Geuna, M.4
Naldini, L.5
-
27
-
-
0034199171
-
Transduction of human CD34+CD38- bone marrow and cord blood-derived SCID-repopulating cells with third-generation lentiviral vectors
-
Guenechea G, Gan OI, Inamitsu T, Dorrell C, Pereira DS, Kelly M et al. Transduction of human CD34+CD38- bone marrow and cord blood-derived SCID-repopulating cells with third-generation lentiviral vectors. Mol Ther 2000; 1: 566-573.
-
(2000)
Mol. Ther.
, vol.1
, pp. 566-573
-
-
Guenechea, G.1
Gan, O.I.2
Inamitsu, T.3
Dorrell, C.4
Pereira, D.S.5
Kelly, M.6
-
28
-
-
0026581239
-
Cytokine stimulation of multilineage hematopoiesis from immature human cells engrafted in SCID mice
-
Lapidot T, Pflumio F, Doedens M, Murdoch B, Williams DE, Dick JE. Cytokine stimulation of multilineage hematopoiesis from immature human cells engrafted in SCID mice. Science 1992; 255: 1137-1141.
-
(1992)
Science
, vol.255
, pp. 1137-1141
-
-
Lapidot, T.1
Pflumio, F.2
Doedens, M.3
Murdoch, B.4
Williams, D.E.5
Dick, J.E.6
-
29
-
-
0030916733
-
Primitive human hematopoietic cells are enriched in cord blood compared with adult bone marrow or mobilized peripheral blood as measured by the quantitative in vivo SCID-repopulating cell assay
-
Wang JC, Doedens M, Dick JE. Primitive human hematopoietic cells are enriched in cord blood compared with adult bone marrow or mobilized peripheral blood as measured by the quantitative in vivo SCID-repopulating cell assay. Blood 1997; 89: 3919-3924.
-
(1997)
Blood
, vol.89
, pp. 3919-3924
-
-
Wang, J.C.1
Doedens, M.2
Dick, J.E.3
-
30
-
-
0028281703
-
Immature human cord blood progenitors engraft and proliferate to high levels in severe combined immunodeficient mice
-
Vormoor J, Lapidot T, Pflumio F, Risdon G, Patterson B, Broxmeyer HE et al. Immature human cord blood progenitors engraft and proliferate to high levels in severe combined immunodeficient mice. Blood 1994; 83: 2489-2497.
-
(1994)
Blood
, vol.83
, pp. 2489-2497
-
-
Vormoor, J.1
Lapidot, T.2
Pflumio, F.3
Risdon, G.4
Patterson, B.5
Broxmeyer, H.E.6
-
31
-
-
0038379165
-
Rapid myeloerythroid repopulation after intrafemoral transplantation of NOD-SCID mice reveals a new class of human stem cells
-
Mazurier F, Doedens M, Gan OI, Dick JE. Rapid myeloerythroid repopulation after intrafemoral transplantation of NOD-SCID mice reveals a new class of human stem cells. Nat Med 2003; 9: 959-963.
-
(2003)
Nat. Med.
, vol.9
, pp. 959-963
-
-
Mazurier, F.1
Doedens, M.2
Gan, O.I.3
Dick, J.E.4
-
32
-
-
0037108189
-
Polyclonal long-term repopulating stem cell clones in a primate model
-
Schmidt M, Zickler P, Hoffmann G, Haas S, Wissler M, Muessig A et al. Polyclonal long-term repopulating stem cell clones in a primate model. Blood 2002; 100: 2737-2743.
-
(2002)
Blood
, vol.100
, pp. 2737-2743
-
-
Schmidt, M.1
Zickler, P.2
Hoffmann, G.3
Haas, S.4
Wissler, M.5
Muessig, A.6
-
33
-
-
0001816041
-
Banding Techniques
-
Pennington JE, Sheinis LA (eds). 2nd edn. New York: McGraw Hill Inc
-
Verma RS, Babu A. Banding Techniques. In: Pennington JE, Sheinis LA (eds). Human Chromosomes: Principles and Techniques, 2nd edn. New York: McGraw Hill Inc, 1995, pp 74-75.
-
(1995)
Human Chromosomes: Principles and Techniques
, pp. 74-75
-
-
Verma, R.S.1
Babu, A.2
-
34
-
-
0028564951
-
Specific association of human telomerase activity with immortal cells and cancer
-
Kim NW, Piatyszek MA, Prowse KR, Harley CB, West MD, Ho PL et al. Specific association of human telomerase activity with immortal cells and cancer. Science 1994; 266: 2011-2015.
-
(1994)
Science
, vol.266
, pp. 2011-2015
-
-
Kim, N.W.1
Piatyszek, M.A.2
Prowse, K.R.3
Harley, C.B.4
West, M.D.5
Ho, P.L.6
-
35
-
-
0037673984
-
Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells
-
Lessard J, Sauvageau G. Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells. Nature 2003; 423: 255-260.
-
(2003)
Nature
, vol.423
, pp. 255-260
-
-
Lessard, J.1
Sauvageau, G.2
-
36
-
-
0038349957
-
Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells
-
Park IK, Qian D, Kiel M, Becker MW, Pihalja M, Weissman IL et al. Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells. Nature 2003; 423: 302-305.
-
(2003)
Nature
, vol.423
, pp. 302-305
-
-
Park, I.K.1
Qian, D.2
Kiel, M.3
Becker, M.W.4
Pihalja, M.5
Weissman, I.L.6
-
37
-
-
0027525653
-
Characterization and chromosomal localization of the human proto-oncogene BMI-1
-
Alkema MJ, Wiegant J, Raap AK, Berns A, Van Lohuizen M. Characterization and chromosomal localization of the human proto-oncogene BMI-1. Hum Mol Genet 1993; 2: 1597-1603.
-
(1993)
Hum. Mol. Genet.
, vol.2
, pp. 1597-1603
-
-
Alkema, M.J.1
Wiegant, J.2
Raap, A.K.3
Berns, A.4
Van Lohuizen, M.5
-
38
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000; 100 57-70.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
39
-
-
0030964322
-
Clinical implications of telomerase activity levels in acute leukemia
-
Ohyashiki JH, Ohyashiki K, Iwama H, Hayashi S, Toyama K, Shay JW. Clinical implications of telomerase activity levels in acute leukemia. Clin Cancer Res 1997; 3: 619-625.
-
(1997)
Clin. Cancer Res.
, vol.3
, pp. 619-625
-
-
Ohyashiki, J.H.1
Ohyashiki, K.2
Iwama, H.3
Hayashi, S.4
Toyama, K.5
Shay, J.W.6
-
40
-
-
0035871680
-
Overexpression of HOXA10 perturbs human lymphomyelopoiesis in vitro and in vivo
-
Buske C, Feuring-Buske M, Antonchuk J, Rosten P, Hogge DE, Eaves CJ et al. Overexpression of HOXA10 perturbs human lymphomyelopoiesis in vitro and in vivo. Blood 2001; 97: 2286-2292.
-
(2001)
Blood
, vol.97
, pp. 2286-2292
-
-
Buske, C.1
Feuring-Buske, M.2
Antonchuk, J.3
Rosten, P.4
Hogge, D.E.5
Eaves, C.J.6
-
41
-
-
0033011006
-
Selection, the mutation rate and cancer: Ensuring that the tail does not wag the dog
-
Tomlinson I, Bodmer W. Selection, the mutation rate and cancer: Ensuring that the tail does not wag the dog. Nat Med 1999; 5: 11-12.
-
(1999)
Nat. Med.
, vol.5
, pp. 11-12
-
-
Tomlinson, I.1
Bodmer, W.2
-
42
-
-
0034661141
-
Trisomy 10 in acute myeloid leukemia
-
Three additional cases from the database of the Japan Adult Leukemia Study Group (JALSG) AML-92 and AML-95
-
Suzuki A, Kimura Y, Ohyashiki K, Kitano K, Kageyama S, Kasai M et al. Trisomy 10 in acute myeloid leukemia. Three additional cases from the database of the Japan Adult Leukemia Study Group (JALSG) AML-92 and AML-95. Cancer Genet Cytogenet 2000; 120: 141-143.
-
(2000)
Cancer Genet. Cytogenet.
, vol.120
, pp. 141-143
-
-
Suzuki, A.1
Kimura, Y.2
Ohyashiki, K.3
Kitano, K.4
Kageyama, S.5
Kasai, M.6
-
43
-
-
0034655512
-
Trisomy 10 in acute myeloid leukemia: Three new cases
-
Llewellyn IE, Morris CM, Stanworth S, Heaton DC, Spearing RL. Trisomy 10 in acute myeloid leukemia: Three new cases. Cancer Genet Cytogenet 2000; 118: 148-150.
-
(2000)
Cancer Genet. Cytogenet.
, vol.118
, pp. 148-150
-
-
Llewellyn, I.E.1
Morris, C.M.2
Stanworth, S.3
Heaton, D.C.4
Spearing, R.L.5
-
46
-
-
0032519809
-
Stage-specific expression of polycomb group genes in human bone marrow cells
-
Lessard J, Baban S, Sauvageau G. Stage-specific expression of polycomb group genes in human bone marrow cells. Blood 1998; 91: 1216-1224.
-
(1998)
Blood
, vol.91
, pp. 1216-1224
-
-
Lessard, J.1
Baban, S.2
Sauvageau, G.3
-
47
-
-
0019424261
-
Granulopoietic differentiation in AML blasts in culture
-
Marie JP, Izaguirre CA, Civin CI, Mirro J, McCulloch EA. Granulopoietic differentiation in AML blasts in culture. Blood 1981; 58: 670-674.
-
(1981)
Blood
, vol.58
, pp. 670-674
-
-
Marie, J.P.1
Izaguirre, C.A.2
Civin, C.I.3
Mirro, J.4
McCulloch, E.A.5
-
48
-
-
0021015301
-
Use of surface markers to identify a subset of acute myelomonocytic leukemia cells with progenitor cell properties
-
Griffin JD, Larcom P, Schlossman SF. Use of surface markers to identify a subset of acute myelomonocytic leukemia cells with progenitor cell properties. Blood 1983; 62: 1300-1303.
-
(1983)
Blood
, vol.62
, pp. 1300-1303
-
-
Griffin, J.D.1
Larcom, P.2
Schlossman, S.F.3
-
49
-
-
0032504051
-
Loops, lineage, and leukemia
-
Enver T, Greaves M. Loops, lineage, and leukemia. Cell 1998; 94 9-12.
-
(1998)
Cell
, vol.94
, pp. 9-12
-
-
Enver, T.1
Greaves, M.2
|