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Volumn 13, Issue 9, 2010, Pages 413-422

The incriminating role of reactive oxygen species in idiopathic male infertility: An evidence based evaluation

Author keywords

Infertility; Oxidative stress; Reactive oxygen species

Indexed keywords

REACTIVE OXYGEN METABOLITE;

EID: 77953988287     PISSN: 10288880     EISSN: 18125735     Source Type: Journal    
DOI: 10.3923/pjbs.2010.413.422     Document Type: Article
Times cited : (98)

References (125)
  • 1
    • 0036866727 scopus 로고    scopus 로고
    • Role of oxidants in male infertility: Rationale, significance and treatment
    • Agarwal, A. and A. Saleh, 2002. Role of oxidants in male infertility: Rationale, significance and treatment. Urol. Clin., 29: 616-627.
    • (2002) Urol. Clin , vol.29 , pp. 616-627
    • Agarwal, A.1    Saleh, A.2
  • 2
    • 2942521602 scopus 로고    scopus 로고
    • Role of antioxidants in treatment of male infertility: An overview of the literature
    • Agarwal, A., K.P. Nallella, S.S. Allamaneni and T.M. Said, 2004. Role of antioxidants in treatment of male infertility: An overview of the literature. Reprod. Biomed. Online, 8: 616-627.
    • (2004) Reprod. Biomed. Online , vol.8 , pp. 616-627
    • Agarwal, A.1    Nallella, K.P.2    Allamaneni, S.S.3    Said, T.M.4
  • 3
  • 4
    • 0024427034 scopus 로고
    • Generation of reactive oxygen species, lipid peroxidation and human sperm function
    • Aitken, R.J., J.S. Clarkson and S. Fishel, 1989. Generation of reactive oxygen species, lipid peroxidation and human sperm function. Biol. Reprod, 41: 183-187.
    • (1989) Biol. Reprod , vol.41 , pp. 183-187
    • Aitken, R.J.1    Clarkson, J.S.2    Fishel, S.3
  • 5
    • 0027199833 scopus 로고
    • Analysis of lipid peroxidation mechanisms in human spermatozoa
    • Aitken, R.J., D. Harkiss and D.W. Buckingham, 1993. Analysis of lipid peroxidation mechanisms in human spermatozoa. Mol. Reproduct. Dev., 35: 302-315.
    • (1993) Mol. Reproduct. Dev , vol.35 , pp. 302-315
    • Aitken, R.J.1    Harkiss, D.2    Buckingham, D.W.3
  • 6
    • 0028409709 scopus 로고
    • Reactive oxygen species generation and human spermatozoa: The balance of benefit and risk
    • Aitken, R.J. and H. Fisher, 1994. Reactive oxygen species generation and human spermatozoa: The balance of benefit and risk. Bioessays, 16: 259-267.
    • (1994) Bioessays , vol.16 , pp. 259-267
    • Aitken, R.J.1    Fisher, H.2
  • 7
    • 0029451739 scopus 로고
    • Free radicals, lipid peroxidation and sperm function
    • Aitken, R.J., 1995. Free radicals, lipid peroxidation and sperm function. Reproduct. Fértil. Dev., 7: 659-668.
    • (1995) Reproduct. Fértil. Dev , vol.7 , pp. 659-668
    • Aitken, R.J.1
  • 8
    • 0033046440 scopus 로고    scopus 로고
    • The Amoroso lecture: The human spermatozoon a cell in crisis
    • Aitken, R.J., 1999. The Amoroso lecture: The human spermatozoon a cell in crisis. J. Reprod. Feit, 115: 1-7.
    • (1999) J. Reprod. Feit , vol.115 , pp. 1-7
    • Aitken, R.J.1
  • 9
    • 0034758449 scopus 로고    scopus 로고
    • Oxidative stress, DNA damage and the Y chromosome
    • Aitken, R.J. and C. Krause, 2001. Oxidative stress, DNA damage and the Y chromosome. Reproduction, 122:497-506.
    • (2001) Reproduction , vol.122 , pp. 497-506
    • Aitken, R.J.1    Krause, C.2
  • 10
    • 4444320760 scopus 로고    scopus 로고
    • Oxidative stress and male reproductive biology
    • Aitken, R.J. and M.A. Baker, 2003. Oxidative stress and male reproductive biology. Reprod. Fértil Dev., 16: 581-588.
    • (2003) Reprod. Fértil Dev , vol.16 , pp. 581-588
    • Aitken, R.J.1    Baker, M.A.2
  • 11
    • 20344405740 scopus 로고    scopus 로고
    • Impact of radio frequency electromagnetic radiation on DNA integrity in the male germline
    • Aitken, R.J., L.E. Bennetts, D. Sawyer, A.M. Wiklendt and B.V. King, 2005. Impact of radio frequency electromagnetic radiation on DNA integrity in the male germline. Int. J. Androl., 28: 171-179.
    • (2005) Int. J. Androl , vol.28 , pp. 171-179
    • Aitken, R.J.1    Bennetts, L.E.2    Sawyer, D.3    Wiklendt, A.M.4    King, B.V.5
  • 12
    • 33646178622 scopus 로고    scopus 로고
    • Oxidative stress, sperm survival and fertility control
    • Aitken, R.J. and M.A. Baker, 2006. Oxidative stress, sperm survival and fertility control. Mol. Cell. Endocrinol., 250: 66-69.
    • (2006) Mol. Cell. Endocrinol , vol.250 , pp. 66-69
    • Aitken, R.J.1    Baker, M.A.2
  • 13
    • 77649219526 scopus 로고    scopus 로고
    • On the possible origins of DNA damage in human spermatozoa
    • Aitken, R.J. and G.N. de Iulus, 2010. On the possible origins of DNA damage in human spermatozoa. Mol. Human Reprod, 16: 3-13.
    • (2010) Mol. Human Reprod , vol.16 , pp. 3-13
    • Aitken, R.J.1    de Iulus, G.N.2
  • 14
    • 0021063651 scopus 로고
    • Taurine, hypotaurine, epinephrine and albumin inhibit lipid peroxidation in rabbit spermatozoa and protect against loss of motility
    • Alvarez, J.G. and B.T. Storey, 1983. Taurine, hypotaurine, epinephrine and albumin inhibit lipid peroxidation in rabbit spermatozoa and protect against loss of motility. Biol. Reprod., 29: 548-555.
    • (1983) Biol. Reprod , vol.29 , pp. 548-555
    • Alvarez, J.G.1    Storey, B.T.2
  • 15
    • 0024337024 scopus 로고
    • Role of glutathione peroxidase in protecting mammalian spermatozoa from loss of motility caused by spontaneous lipid peroxidation
    • Alvarez, J.G. and B.T. Storey, 1989. Role of glutathione peroxidase in protecting mammalian spermatozoa from loss of motility caused by spontaneous lipid peroxidation. Gamete Res., 23: 77-90.
    • (1989) Gamete Res , vol.23 , pp. 77-90
    • Alvarez, J.G.1    Storey, B.T.2
  • 16
    • 0028891932 scopus 로고
    • Differential incorporation of fatty acids into and peroidative loss of fatty acids from phospholilipds of human spermatozoa
    • Alvarez, J.G. and B.T. Storey, 1995. Differential incorporation of fatty acids into and peroidative loss of fatty acids from phospholilipds of human spermatozoa. Mol. Reprod. Dev., 42: 334-346.
    • (1995) Mol. Reprod. Dev , vol.42 , pp. 334-346
    • Alvarez, J.G.1    Storey, B.T.2
  • 17
    • 0642281878 scopus 로고    scopus 로고
    • Nurture vs nature: How can we optimize sperm quality?
    • Alvarez, J.G., 2003. Nurture vs nature: How can we optimize sperm quality?. J. AndroL, 24: 640-648.
    • (2003) J. AndroL , vol.24 , pp. 640-648
    • Alvarez, J.G.1
  • 19
    • 13944278132 scopus 로고    scopus 로고
    • Mitochondria, oxidants and aging
    • Balaban, R.S., S. Nemoto and T. Finkel, 2005. Mitochondria, oxidants and aging. Cell, 120: 483-495.
    • (2005) Cell , vol.120 , pp. 483-495
    • Balaban, R.S.1    Nemoto, S.2    Finkel, T.3
  • 21
    • 0027562849 scopus 로고
    • Varicocele in childhood and adolescence and other testicular anomalies: An epidemiological study
    • Belloh, G., S. D'Agostino, C. Pesce and E. Fantuz, 1993. Varicocele in childhood and adolescence and other testicular anomalies: An epidemiological study. Pediati. Med. Chir., 15: 159-162.
    • (1993) Pediati. Med. Chir , vol.15 , pp. 159-162
    • Belloh, G.1    D'Agostino, S.2    Pesce, C.3    Fantuz, E.4
  • 22
    • 16344377052 scopus 로고    scopus 로고
    • A comparative study of oxidative DNA damage in mammalian spermatozoa
    • Bennetts, L.E. and R.J. Aitken, 2005. A comparative study of oxidative DNA damage in mammalian spermatozoa. Mol. Reprod. Dev., 71: 77-87.
    • (2005) Mol. Reprod. Dev , vol.71 , pp. 77-87
    • Bennetts, L.E.1    Aitken, R.J.2
  • 24
    • 58149091691 scopus 로고    scopus 로고
    • Oxidative stress, lens cap junctions and cataracts
    • Berthood, V.M. and E.C. Beyer, 2009. Oxidative stress, lens cap junctions and cataracts. Antioxidants Redox Signaling, 11: 339-354.
    • (2009) Antioxidants Redox Signaling , vol.11 , pp. 339-354
    • Berthood, V.M.1    Beyer, E.C.2
  • 25
    • 0027251053 scopus 로고
    • The peeking order of free radicals and antioxidants: Lipid peroxidation, á-tocopherol and ascorbate
    • Buetrner, K., 1993. The peeking order of free radicals and antioxidants: Lipid peroxidation, á-tocopherol and ascorbate. Arch. Biochem. Biophys., 300: 535-543.
    • (1993) Arch. Biochem. Biophys , vol.300 , pp. 535-543
    • Buetrner, K.1
  • 26
    • 0027177490 scopus 로고
    • An introduction to free radical biochemistry
    • Cheeseman, K.H. and T.F. Slater, 1993. An introduction to free radical biochemistry. Br. Med. Bull., 49: 481-493.
    • (1993) Br. Med. Bull , vol.49 , pp. 481-493
    • Cheeseman, K.H.1    Slater, T.F.2
  • 28
    • 0033954991 scopus 로고    scopus 로고
    • Oxidative stress and Alzheimer disease
    • Christen, Y., 2000. Oxidative stress and Alzheimer disease. Am. J. Clin. Nutr., 71: 6215-6295.
    • (2000) Am. J. Clin. Nutr , vol.71 , pp. 6215-6295
    • Christen, Y.1
  • 29
    • 0032949602 scopus 로고    scopus 로고
    • Oxidatine stress and motor neurone disease
    • Cookson, M. and P. Shaw, 1999. Oxidatine stress and motor neurone disease. Brain Pathol, 9: 165-186.
    • (1999) Brain Pathol , vol.9 , pp. 165-186
    • Cookson, M.1    Shaw, P.2
  • 30
    • 0029144638 scopus 로고
    • Nitric oxide and oxygen radicals: A question of balance
    • Darley-Usmar, V., H. Wiseman and B. Halliwell, 1995. Nitric oxide and oxygen radicals: A question of balance. FEBS Lett, 369: 131-135.
    • (1995) FEBS Lett , vol.369 , pp. 131-135
    • Darley-Usmar, V.1    Wiseman, H.2    Halliwell, B.3
  • 31
    • 13244258258 scopus 로고    scopus 로고
    • Lipid peroxidation in Diabetis mellitus
    • Davi, G., A. Falco and C. Patrono, 2005. Lipid peroxidation in Diabetis mellitus. AntiotidRedox Signal, 7: 256-258.
    • (2005) AntiotidRedox Signal , vol.7 , pp. 256-258
    • Davi, G.1    Falco, A.2    Patrono, C.3
  • 32
    • 0028834966 scopus 로고
    • Impact of reactive oxygen species on spermatozoa: A balancing act between beneficial and detrimental effects
    • De Lamirande E. and C. Gagnon, 1995. Impact of reactive oxygen species on spermatozoa: A balancing act between beneficial and detrimental effects. Human Reprod., 10: 15-21.
    • (1995) Human Reprod , vol.10 , pp. 15-21
    • de Lamirande, E.1    Gagnon, C.2
  • 33
    • 0031793041 scopus 로고    scopus 로고
    • Involvement of reactive oxygen species in human sperm arcosome reaction induced by A23187, lysophosphatidylcholme and biological fluid ultrafiltrates
    • De Lamirande, E., C. Tsai, A. Harakat and C. Gagnon, 1998. Involvement of reactive oxygen species in human sperm arcosome reaction induced by A23187, lysophosphatidylcholme and biological fluid ultrafiltrates. J. AndroL, 19: 585-594.
    • (1998) J. AndroL , vol.19 , pp. 585-594
    • de Lamirande, E.1    Tsai, C.2    Harakat, A.3    Gagnon, C.4
  • 35
    • 0033638475 scopus 로고    scopus 로고
    • Effects of hydrogen peroxide on DNA and plasma membrane integrity of human spermatozoa
    • Duru, N.K., M. Morshedi and S. Oehninger, 2000. Effects of hydrogen peroxide on DNA and plasma membrane integrity of human spermatozoa. Fertil. Steril., 74: 1200-1207.
    • (2000) Fertil. Steril , vol.74 , pp. 1200-1207
    • Duru, N.K.1    Morshedi, M.2    Oehninger, S.3
  • 36
    • 0036708435 scopus 로고    scopus 로고
    • Effect of leukocytospermia on sperm DNA integrity: A negative effect in abnormal semen samples
    • Erenpreiss, J., S. Hlevicka, J. Zalkalns and J. Erenpreisa, 2002. Effect of leukocytospermia on sperm DNA integrity: A negative effect in abnormal semen samples. J. AndroL, 23: 717-723.
    • (2002) J. AndroL , vol.23 , pp. 717-723
    • Erenpreiss, J.1    Hlevicka, S.2    Zalkalns, J.3    Erenpreisa, J.4
  • 38
    • 0033822354 scopus 로고    scopus 로고
    • Characteristics of human sperm chromatin structure following an episode of influenza and high fever: A case study
    • Evenson, D., L. Jost, M. Corzett and R. Balhorn, 2000. Characteristics of human sperm chromatin structure following an episode of influenza and high fever: A case study. J. AndroL, 21: 739-465.
    • (2000) J. AndroL , vol.21 , pp. 739-465
    • Evenson, D.1    Jost, L.2    Corzett, M.3    Balhorn, R.4
  • 39
    • 0029917272 scopus 로고    scopus 로고
    • Smoking and low antioxidants levels increase oxidative damage to sperm DNA
    • Fraga, G.G., P.A. Motchnik, A.J. Wyrobek, D.M. Rempel and B. Ames, 1996. Smoking and low antioxidants levels increase oxidative damage to sperm DNA. Mutat. Res., 351: 199-203.
    • (1996) Mutat. Res , vol.351 , pp. 199-203
    • Fraga, G.G.1    Motchnik, P.A.2    Wyrobek, A.J.3    Rempel, D.M.4    Ames, B.5
  • 40
    • 1842483365 scopus 로고    scopus 로고
    • Pro-oxidative and anti-oxidative imbalance in human semen and its relation with male fertility
    • Garrido, N., M. Meseguer, C. Simon, A. Pellicer and J. Remohi, 2004. Pro-oxidative and anti-oxidative imbalance in human semen and its relation with male fertility. Asian J. AndroL, 6: 59-65.
    • (2004) Asian J. AndroL , vol.6 , pp. 59-65
    • Garrido, N.1    Meseguer, M.2    Simon, C.3    Pellicer, A.4    Remohi, J.5
  • 41
    • 0031028096 scopus 로고    scopus 로고
    • Evaluation of ascorbate and urate antioxidant capacity in human semen
    • Gavella, M., V. Lipovac, M. Vucic and B. Rocic, 1997. Evaluation of ascorbate and urate antioxidant capacity in human semen. Andrologia, 29: 29-35.
    • (1997) Andrologia , vol.29 , pp. 29-35
    • Gavella, M.1    Lipovac, V.2    Vucic, M.3    Rocic, B.4
  • 42
    • 0035112896 scopus 로고    scopus 로고
    • Chronic granulomatous disease: More than the lack of superoxide?
    • Geiszt, M., A. Kapus and E. Ligeti, 2001. Chronic granulomatous disease: More than the lack of superoxide?. J. Leukoc. Biol., 69: 191-196.
    • (2001) J. Leukoc. Biol , vol.69 , pp. 191-196
    • Geiszt, M.1    Kapus, A.2    Ligeti, E.3
  • 43
    • 37849021505 scopus 로고    scopus 로고
    • Bionegative and biopositive effects of free radicals
    • Gomez-Cabera, M., 2008. Bionegative and biopositive effects of free radicals. Free Radical Biol. Med., 44: 126-131.
    • (2008) Free Radical Biol. Med , vol.44 , pp. 126-131
    • Gomez-Cabera, M.1
  • 44
    • 18144397261 scopus 로고    scopus 로고
    • The genetic and cytogenetic basis of male infertility
    • Griffin, D.K. and K.A. Finch, 2005. The genetic and cytogenetic basis of male infertility. Human Fertil., 8: 19-26.
    • (2005) Human Fertil , vol.8 , pp. 19-26
    • Griffin, D.K.1    Finch, K.A.2
  • 45
    • 0030820190 scopus 로고    scopus 로고
    • Reactive oxygen species and human spermatozoa: Physiology and pathology
    • Griveau, J. and D. Le Lannou, 1997. Reactive oxygen species and human spermatozoa: Physiology and pathology. Int. J. AndroL, 20: 61-69.
    • (1997) Int. J. AndroL , vol.20 , pp. 61-69
    • Griveau, J.1    Lannou, D.L.2
  • 46
    • 0028965632 scopus 로고
    • Reactive oxygen species, lipid peroxidation and enzymatic defence systems in human spermatozoa
    • Griveau, J.F., E. Dumont, P. Renard, J.P. Callegari and D. le Lannou, 1995. Reactive oxygen species, lipid peroxidation and enzymatic defence systems in human spermatozoa. J. Reprod. Fertil., 103: 17-26.
    • (1995) J. Reprod. Fertil , vol.103 , pp. 17-26
    • Griveau, J.F.1    Dumont, E.2    Renard, P.3    Callegari, J.P.4    Lannou, D.L.5
  • 47
    • 17444364399 scopus 로고    scopus 로고
    • Caspase activation in human spermatozoa in response to physiological and pathological stimuli
    • Grunewald, S., U. Paasch, T.M. Said, R.K. Sharma, H.J. Glander and A. Agarwal, 2005. Caspase activation in human spermatozoa in response to physiological and pathological stimuli. Fertil. Steril., 83: 1106-1102.
    • (2005) Fertil. Steril , vol.83 , pp. 1106-1102
    • Grunewald, S.1    Paasch, U.2    Said, T.M.3    Sharma, R.K.4    Glander, H.J.5    Agarwal, A.6
  • 48
    • 0025069762 scopus 로고
    • How to characterize a biological antioxidant
    • Halliwell, B., 1990. How to characterize a biological antioxidant. Free Raical Res. Commun., 9: 1-32.
    • (1990) Free Raical Res. Commun , vol.9 , pp. 1-32
    • Halliwell, B.1
  • 50
    • 0032829436 scopus 로고    scopus 로고
    • Varicocele is associated with elevated spermatozoal reactive oxygen species production and diminished seminal plasma antioxidant capacity
    • Hendin, B.N., P.N. Kolettis, R.K. Sharma, A.J. Jr. Thomas and A. Agarwal, 1999. Varicocele is associated with elevated spermatozoal reactive oxygen species production and diminished seminal plasma antioxidant capacity. J. Urol, 161: 1831-1834.
    • (1999) J. Urol , vol.161 , pp. 1831-1834
    • Hendin, B.N.1    Kolettis, P.N.2    Sharma, R.K.3    Thomas Jr., A.J.4    Agarwal, A.5
  • 51
    • 14444284368 scopus 로고    scopus 로고
    • Spontaneous germ cell apoptosis in humans: Evidence for ethnic differences in the susceptibility of germ cells to programmed cell death
    • Hikim, A.P., C. Wang, Y. Lue, L. Johnson, X.H. Wang and R.S. Swerdloff, 1998. Spontaneous germ cell apoptosis in humans: Evidence for ethnic differences in the susceptibility of germ cells to programmed cell death. J. Clin Endocrinol. Metab., 83: 152-156.
    • (1998) J. Clin Endocrinol. Metab , vol.83 , pp. 152-156
    • Hikim, A.P.1    Wang, C.2    Lue, Y.3    Johnson, L.4    Wang, X.H.5    Swerdloff, R.S.6
  • 52
    • 8544232149 scopus 로고    scopus 로고
    • Oxidative stress in rheumathoid arthritis
    • Hitchon, C, 2004. Oxidative stress in rheumathoid arthritis. Res. Therpy, 6: 265-278.
    • (2004) Res. Therpy , vol.6 , pp. 265-278
    • Hitchon, C.1
  • 53
    • 34548435756 scopus 로고    scopus 로고
    • Increased testicular 8-hydroxy-2'-deoxyguanosine in patients with varicocele
    • Ishikawa, T., H. Fujioka, T. Ishimura, A. Takenake and M. Fujisawa, 2007. Increased testicular 8-hydroxy-2'-deoxyguanosine in patients with varicocele. B.JU Int., 100: 863-866.
    • (2007) B.JU Int , vol.100 , pp. 863-866
    • Ishikawa, T.1    Fujioka, H.2    Ishimura, T.3    Takenake, A.4    Fujisawa, M.5
  • 54
    • 0026540891 scopus 로고
    • Formation of reactive oxygen species in spermatozoa of infertile patients
    • Iwasaki, A. and C. Gagnon, 1992. Formation of reactive oxygen species in spermatozoa of infertile patients. Fert. Ster., 57: 409-416.
    • (1992) Fert. Ster , vol.57 , pp. 409-416
    • Iwasaki, A.1    Gagnon, C.2
  • 56
    • 74549193401 scopus 로고    scopus 로고
    • What has happened to human fertility?
    • Joffe, M., 2010. What has happened to human fertility?. Human Reprod., 25: 295-307.
    • (2010) Human Reprod , vol.25 , pp. 295-307
    • Joffe, M.1
  • 57
    • 0018341406 scopus 로고
    • Peroxidative breakdown of phospholipids in human spermatozoa, spemicidal properties of fatty acid peroxides and protective action of seminal plasma
    • Jones, R., T. Mann and R. Sherins, 1979. Peroxidative breakdown of phospholipids in human spermatozoa, spemicidal properties of fatty acid peroxides and protective action of seminal plasma. Fertil. Steril., 31: 531-537.
    • (1979) Fertil. Steril , vol.31 , pp. 531-537
    • Jones, R.1    Mann, T.2    Sherins, R.3
  • 58
    • 0032918641 scopus 로고    scopus 로고
    • DNA damage in round spermatids of mice with a targeted disruption of the Ppl cgamma gene and in testicular biopsies of patients with non-obstructive azoospermia
    • Jurisicova, A., S. Lopes, J. Meriano, L. Oppedisano, R.F. Casper and S. Varmuza, 1999. DNA damage in round spermatids of mice with a targeted disruption of the Ppl cgamma gene and in testicular biopsies of patients with non-obstructive azoospermia. Mol. Human Reprod., 5: 323-330.
    • (1999) Mol. Human Reprod , vol.5 , pp. 323-330
    • Jurisicova, A.1    Lopes, S.2    Meriano, J.3    Oppedisano, L.4    Casper, R.F.5    Varmuza, S.6
  • 60
    • 0000320310 scopus 로고    scopus 로고
    • Glutathione: Systemic protectant against oxidative and free radical damage
    • Kidd, P., 1997. Glutathione: Systemic protectant against oxidative and free radical damage. Alt. Med. Rev., 2: 155-176.
    • (1997) Alt. Med. Rev , vol.2 , pp. 155-176
    • Kidd, P.1
  • 61
    • 0029926964 scopus 로고    scopus 로고
    • Effect of sperm lipid peroxidation on fertilization
    • Kodama, H., Y. Kuribayashi and C. Gagnon, 1996. Effect of sperm lipid peroxidation on fertilization. J. Androl., 17: 151-157.
    • (1996) J. Androl , vol.17 , pp. 151-157
    • Kodama, H.1    Kuribayashi, Y.2    Gagnon, C.3
  • 62
    • 0343907222 scopus 로고    scopus 로고
    • Increased oxidative deoxyribonucleic acid damage in the spermatozoa of infertile male patients
    • Kodama, H., R. Yamaguchi, J. Fukuda, H. Kasai and T. Tanaka, 1997. Increased oxidative deoxyribonucleic acid damage in the spermatozoa of infertile male patients. Fertil. Steril., 68: 519-524.
    • (1997) Fertil. Steril , vol.68 , pp. 519-524
    • Kodama, H.1    Yamaguchi, R.2    Fukuda, J.3    Kasai, H.4    Tanaka, T.5
  • 65
    • 0344753770 scopus 로고
    • Reactive oxygen species and human spermatozoa. I. Effects on the motility of intact spermatozoa and on sperm axoneme and II. Depletion of adenosine triphosphate plays an important role in the inhibition of sperm motility
    • Lamir and e, E. and C. Gagnon
    • Lamir and e, E. and C. Gagnon, 1992. Reactive oxygen species and human spermatozoa. I. Effects on the motility of intact spermatozoa and on sperm axoneme and II. Depletion of adenosine triphosphate plays an important role in the inhibition of sperm motility. J. Androl, 13:379-386.
    • (1992) J. Androl , vol.13 , pp. 379-386
  • 66
    • 0032910202 scopus 로고    scopus 로고
    • The Fas system, a regulator of testicular germ cell apoptosis is differentially up-regulated in Sertoli cell versus germ cell injury of the testis
    • Lee, J., J.H. Richburg, E.B. Shipp, M.L. Meistrich and K. Boekelheide, 1999. The Fas system, a regulator of testicular germ cell apoptosis is differentially up-regulated in Sertoli cell versus germ cell injury of the testis. Endocrmology, 140: 852-858.
    • (1999) Endocrmology , vol.140 , pp. 852-858
    • Lee, J.1    Richburg, J.H.2    Shipp, E.B.3    Meistrich, M.L.4    Boekelheide, K.5
  • 67
    • 0016515782 scopus 로고
    • The glutathione and thiol content of mammalian spermatozoa and seminal plasma
    • Li, T.K., 1975. The glutathione and thiol content of mammalian spermatozoa and seminal plasma. Biol. Reprod., 12: 641-646.
    • (1975) Biol. Reprod , vol.12 , pp. 641-646
    • Li, T.K.1
  • 68
    • 0031450241 scopus 로고    scopus 로고
    • In situ end-labeling of human testicular tissue demonstrates increased apoptosis in conditions of abnormal spermatogenesis
    • Lin, W.W., D.J. Lamb, T.M. Wheeler, L.I. Lipshultz and E.D. Kim, 1997. In situ end-labeling of human testicular tissue demonstrates increased apoptosis in conditions of abnormal spermatogenesis. Fertil Steril, 68: 1065-1069.
    • (1997) Fertil Steril , vol.68 , pp. 1065-1069
    • Lin, W.W.1    Lamb, D.J.2    Wheeler, T.M.3    Lipshultz, L.I.4    Kim, E.D.5
  • 69
    • 33747138329 scopus 로고    scopus 로고
    • Alcohol abuse-duration dependent decrease in plasma testosterone and antioxidants in males
    • Maneesh, M., S. Dutta, A. Chakrabarti and D.M. Vasudevan, 2006. Alcohol abuse-duration dependent decrease in plasma testosterone and antioxidants in males. Indian J. Physiol. Pharmacol, 50: 291-296.
    • (2006) Indian J. Physiol. Pharmacol , vol.50 , pp. 291-296
    • Maneesh, M.1    Dutta, S.2    Chakrabarti, A.3    Vasudevan, D.M.4
  • 70
    • 0347316382 scopus 로고    scopus 로고
    • Relationship between ROS production, apoptosis and DNA denaturation in spermatozoa from patients examined for infertility
    • Moustafa, M.H., R.K. Sharma, J. Thornton, E. Mascha, M.A. Abdel-Hafez, A.J. Thomas and A. Agarwal, 2004. Relationship between ROS production, apoptosis and DNA denaturation in spermatozoa from patients examined for infertility. Human Reprod., 19: 129-138.
    • (2004) Human Reprod , vol.19 , pp. 129-138
    • Moustafa, M.H.1    Sharma, R.K.2    Thornton, J.3    Mascha, E.4    Abdel-Hafez, M.A.5    Thomas, A.J.6    Agarwal, A.7
  • 71
    • 33750621068 scopus 로고    scopus 로고
    • Effect of smoking on seminal plasma ascorbic acid in infertile and fertile males
    • Mostafa, T., G. Tawadrous, M.M. Roaia, M.K. Amer, R. A. Kader and A. Aziz, 2006. Effect of smoking on seminal plasma ascorbic acid in infertile and fertile males. Andrologia, 38: 221-224.
    • (2006) Andrologia , vol.38 , pp. 221-224
    • Mostafa, T.1    Tawadrous, G.2    Roaia, M.M.3    Amer, M.K.4    Kader, R.A.5    Aziz, A.6
  • 73
    • 7944229250 scopus 로고    scopus 로고
    • Relationship of interleukin-6 with semen characteristics and oxidative stress in patients with varicocele
    • Nallella, K.P., S.S. Allamaneni, F.F. Pasqualotto, R.K. Sharma, A.J. Jr. Thomas and A. Agarwal, 2004. Relationship of interleukin-6 with semen characteristics and oxidative stress in patients with varicocele. Urology, 64: 1010-1013.
    • (2004) Urology , vol.64 , pp. 1010-1013
    • Nallella, K.P.1    Allamaneni, S.S.2    Pasqualotto, F.F.3    Sharma, R.K.4    Thomas Jr., A.J.5    Agarwal, A.6
  • 74
    • 43949146288 scopus 로고    scopus 로고
    • Sperm DNA fragmentation in subfertile men: The effect on the outcome of intracytoplasmic sperm injection and correlation with sperm variables
    • Nicopoullos, J.D., C. Gilling-Smith, P.A. Almeida, S. Homa, J.Q. Norman-Taylor and J.W. Ramsay, 2008. Sperm DNA fragmentation in subfertile men: The effect on the outcome of intracytoplasmic sperm injection and correlation with sperm variables. BJU Int., 101: 1553-1560.
    • (2008) BJU Int , vol.101 , pp. 1553-1560
    • Nicopoullos, J.D.1    Gilling-Smith, C.2    Almeida, P.A.3    Homa, S.4    Norman-Taylor, J.Q.5    Ramsay, J.W.6
  • 75
    • 0025719364 scopus 로고
    • Action of ascorbic acid as a scavenger of active and stable oxygen radicals
    • Niki, E., 1991. Action of ascorbic acid as a scavenger of active and stable oxygen radicals. Am. J. Clin. Nutr., 54: 1119S-1124S.
    • (1991) Am. J. Clin. Nutr , vol.54
    • Niki, E.1
  • 76
    • 0020676170 scopus 로고
    • Superoxide dismutase in human semen
    • Nissen, H.P. and H.W. Kreysel, 1983. Superoxide dismutase in human semen. Klin Wochenschr, 61: 63-65.
    • (1983) Klin Wochenschr , vol.61 , pp. 63-65
    • Nissen, H.P.1    Kreysel, H.W.2
  • 78
    • 74549179612 scopus 로고    scopus 로고
    • Increased lipid peroxidation and abnormal fatty acid profiles in seminal and blood plasma of normozoospermic males from infertile couples
    • Oborna, I., G. Wojewodka, J.B. de Sanctis, H. Fingerova and M. Svobodova, et al., 2010. Increased lipid peroxidation and abnormal fatty acid profiles in seminal and blood plasma of normozoospermic males from infertile couples. Human Reprod., 25: 308-316.
    • (2010) Human Reprod , vol.25 , pp. 308-316
    • Oborna, I.1    Wojewodka, G.2    de Sanctis, J.B.3    Fingerova, H.4    Svobodova, M.5
  • 79
    • 0032712606 scopus 로고    scopus 로고
    • Infections in the male genital tract and reactive oxygen species
    • Ochsendorf, F.R, 1999. Infections in the male genital tract and reactive oxygen species. Human Reprod. Update, 5: 399-420.
    • (1999) Human Reprod. Update , vol.5 , pp. 399-420
    • Ochsendorf, F.R.1
  • 80
    • 33745255403 scopus 로고    scopus 로고
    • Protamines and male infertility
    • Oliva, R., 2006. Protamines and male infertility. Human Reprod. Update, 12: 417-435.
    • (2006) Human Reprod. Update , vol.12 , pp. 417-435
    • Oliva, R.1
  • 81
    • 25444523824 scopus 로고    scopus 로고
    • An evaluation of chromatin condensation and DNA integrity in the spermatozoa of men with cancer before and after therapy
    • O'Donovan, M., 2005. An evaluation of chromatin condensation and DNA integrity in the spermatozoa of men with cancer before and after therapy. Andrologia, 37: 83-90.
    • (2005) Andrologia , vol.37 , pp. 83-90
    • O'Donovan, M.1
  • 83
    • 33644989289 scopus 로고    scopus 로고
    • A doppler-based study on the prevalence of varicocele in German children and adolescents
    • Pfeiffer, D., J. Berger, C. Schoop and R. Tauber, 2006. A doppler-based study on the prevalence of varicocele in German children and adolescents. Andrologia, 38: 13-19.
    • (2006) Andrologia , vol.38 , pp. 13-19
    • Pfeiffer, D.1    Berger, J.2    Schoop, C.3    Tauber, R.4
  • 85
    • 0034064385 scopus 로고    scopus 로고
    • Germ cell suicide: New insights into apoptosis during spermatogenesis
    • Print, CG and K.L. Lovel and, 2000. Germ cell suicide: New insights into apoptosis during spermatogenesis. Bioessays, 22: 423-430.
    • (2000) Bioessays , vol.22 , pp. 423-430
    • Print, C.G.1    Lovel, K.L.2
  • 86
    • 4744349398 scopus 로고    scopus 로고
    • Structure and regulation of the neutrophil respiratory burst oxidase: Comparison with nonphagocyte oxidases
    • Quinn, M.T. and K.A. Gauss, 2004. Structure and regulation of the neutrophil respiratory burst oxidase: Comparison with nonphagocyte oxidases. J. Leukoc. Biol, 76: 760-781.
    • (2004) J. Leukoc. Biol , vol.76 , pp. 760-781
    • Quinn, M.T.1    Gauss, K.A.2
  • 87
    • 0036796276 scopus 로고    scopus 로고
    • Role of oxidative stress and antioxidants in neurodegenerative diseases
    • Rao, A. and B. Balachandran, 2002. Role of oxidative stress and antioxidants in neurodegenerative diseases. Nutr. Neurosci., 5: 291-309.
    • (2002) Nutr. Neurosci , vol.5 , pp. 291-309
    • Rao, A.1    Balachandran, B.2
  • 88
    • 84907131341 scopus 로고
    • Uridine, xanthine and urate contents in human seminal plasma
    • Ronquist, G. and F. Niklasson, 1984. Uridine, xanthine and urate contents in human seminal plasma. Arch. Androl, 13: 63-70.
    • (1984) Arch. Androl , vol.13 , pp. 63-70
    • Ronquist, G.1    Niklasson, F.2
  • 89
    • 33747367783 scopus 로고    scopus 로고
    • Fertility and a woman's age
    • Rowe, T., 2006. Fertility and a woman's age. J. Reprod. Med., 51: 157-163.
    • (2006) J. Reprod. Med , vol.51 , pp. 157-163
    • Rowe, T.1
  • 90
    • 67650544617 scopus 로고    scopus 로고
    • Grapefruit seed moderates the testicular toxicity associated with experimental varicocele in rats
    • Saalu, L.C., R. Udeh, P.I. Jewo, K.A. Oluyemi and I.O. Fadeyibi, 2008. Grapefruit seed moderates the testicular toxicity associated with experimental varicocele in rats. Int. J. MorphoL, 26: 1059-1064.
    • (2008) Int. J. MorphoL , vol.26 , pp. 1059-1064
    • Saalu, L.C.1    Udeh, R.2    Jewo, P.I.3    Oluyemi, K.A.4    Fadeyibi, I.O.5
  • 91
    • 77949282836 scopus 로고    scopus 로고
    • Ethanol seed extract of graprfruit (Citrus paradisi) as an effective attenuator of doxorubicin-induced oxidative stress in the rat heart
    • Saalu, L.C., G.O. Ajayi, A.A. Adeneye, I.O. Imosemi and A.A. Osinubi, 2009a. Ethanol seed extract of graprfruit (Citrus paradisi) as an effective attenuator of doxorubicin-induced oxidative stress in the rat heart. Int. J. Cancer Res., 5: 44-52.
    • (2009) Int. J. Cancer Res , vol.5 , pp. 44-52
    • Saalu, L.C.1    Ajayi, G.O.2    Adeneye, A.A.3    Imosemi, I.O.4    Osinubi, A.A.5
  • 92
    • 77949305972 scopus 로고    scopus 로고
    • An assessment of the histomorphometric evidences of doxorubicin-induced testicular cytotoxicity in Wistar rats
    • Saalu, L.C., L.A. Enye and A.A. Osmubi, 2009b. An assessment of the histomorphometric evidences of doxorubicin-induced testicular cytotoxicity in Wistar rats. Int. J. Med. Med. Sei., 1: 370-374.
    • (2009) Int. J. Med. Med. Sei , vol.1 , pp. 370-374
    • Saalu, L.C.1    Enye, L.A.2    Osmubi, A.A.3
  • 93
    • 77954015218 scopus 로고    scopus 로고
    • Early and delayed effects of doxorubicin on testicular oxidative status and spermatogenesis in rats
    • Saalu, L.C., A.A. Osinubi and J.A. Olagunju, 2010. Early and delayed effects of doxorubicin on testicular oxidative status and spermatogenesis in rats. Int. J. Cancer Res., 6: 1-9.
    • (2010) Int. J. Cancer Res , vol.6 , pp. 1-9
    • Saalu, L.C.1    Osinubi, A.A.2    Olagunju, J.A.3
  • 95
    • 12144255552 scopus 로고    scopus 로고
    • Impact of sperm morphology on DNA damage caused by oxidative stress induced by beta-nicotinamide adenine dinucleotide phosphate
    • Said, T.M., A. Agarwal, R.K. Sharma, A.J. Jr. Thomas and S.C. Sikka, 2005. Impact of sperm morphology on DNA damage caused by oxidative stress induced by beta-nicotinamide adenine dinucleotide phosphate. Fertil. Steril., 83: 95-103.
    • (2005) Fertil. Steril , vol.83 , pp. 95-103
    • Said, T.M.1    Agarwal, A.2    Sharma, R.K.3    Thomas Jr., A.J.4    Sikka, S.C.5
  • 96
    • 0033567961 scopus 로고    scopus 로고
    • Abnormal sperm parameters in humans are indicative of an abortive apoptotic mechanism linked to the Fas-mediated pathway
    • Sakkas, D., E. Mariethoz and J.C. St. John, 1999a. Abnormal sperm parameters in humans are indicative of an abortive apoptotic mechanism linked to the Fas-mediated pathway. Exp. Cell Res., 251: 350-355.
    • (1999) Exp. Cell Res , vol.251 , pp. 350-355
    • Sakkas, D.1    Mariethoz, E.2    John St., J.C.3
  • 99
    • 0036196244 scopus 로고    scopus 로고
    • Nature of DNA damage in ejaculated human spermatozoa and the possible involvement of apoptosis
    • Sakkas, D., O. Moffatt, G.C. Manicardi, E. Mariethoz, N. Tarozzi and D. Bizzaro, 2002. Nature of DNA damage in ejaculated human spermatozoa and the possible involvement of apoptosis. Biol. Reprod., 66: 1061-1067.
    • (2002) Biol. Reprod , vol.66 , pp. 1061-1067
    • Sakkas, D.1    Moffatt, O.2    Manicardi, G.C.3    Mariethoz, E.4    Tarozzi, N.5    Bizzaro, D.6
  • 100
    • 0348110637 scopus 로고    scopus 로고
    • Evaluation of nuclear DNA damage in spermatozoa from infertile men with varicocele
    • Saleh, R., A. Agarwal, R. Sharma, T. Said, S. Sikka and A. Jr. Thomas, 2003. Evaluation of nuclear DNA damage in spermatozoa from infertile men with varicocele. Fertil. Steril, 80: 1431-1436.
    • (2003) Fertil. Steril , vol.80 , pp. 1431-1436
    • Saleh, R.1    Agarwal, A.2    Sharma, R.3    Said, T.4    Sikka, S.5    Thomas Jr., A.6
  • 101
    • 0036732102 scopus 로고    scopus 로고
    • Effect of cigarette smoking on levels of seminal oxidative stress in infertile men: A prospective study
    • Saleh, R.A., A. Agarwa, R.K. Sharma, D.R. Nelson and A.J. Thomas, 2002. Effect of cigarette smoking on levels of seminal oxidative stress in infertile men: A prospective study. Fert. Ster., 78: 491-499.
    • (2002) Fert. Ster , vol.78 , pp. 491-499
    • Saleh, R.A.1    Agarwa, A.2    Sharma, R.K.3    Nelson, D.R.4    Thomas, A.J.5
  • 102
    • 0027935585 scopus 로고
    • Treatment outcome after varicocelectomy: A critical analysis
    • Schlesinger, M.H., I.F. Wilets and H.M. Nagler, 1994. Treatment outcome after varicocelectomy: A critical analysis. Urol. Clin. North Am., 21: 517-529.
    • (1994) Urol. Clin. North Am , vol.21 , pp. 517-529
    • Schlesinger, M.H.1    Wilets, I.F.2    Nagler, H.M.3
  • 103
    • 2942691425 scopus 로고    scopus 로고
    • Sperm DNA damage and its clinical relevance in assessing reproductive outcome
    • Sharma, R.K., T. Said and A. Agarwal, 2004. Sperm DNA damage and its clinical relevance in assessing reproductive outcome. Asian J. Androl, 6: 139-148.
    • (2004) Asian J. Androl , vol.6 , pp. 139-148
    • Sharma, R.K.1    Said, T.2    Agarwal, A.3
  • 104
    • 0028811108 scopus 로고
    • Incidence and level of seminal reactive oxygen species in normal men
    • Shekarriz, M., A.J. Jr. Thomas and A. Agarwal, 1995a. Incidence and level of seminal reactive oxygen species in normal men. Urology, 45: 103-107.
    • (1995) Urology , vol.45 , pp. 103-107
    • Shekarriz, M.1    Thomas Jr., A.J.2    Agarwal, A.3
  • 105
    • 0028997538 scopus 로고
    • A method of human semen centrifugation to minimize the iatrogenic sperm injuries caused by reactive oxygen species
    • Shekarriz, M., D.M. DeWire, A.J. Jr. Thomas and A. Agarwal, 1995b. A method of human semen centrifugation to minimize the iatrogenic sperm injuries caused by reactive oxygen species. Eur. Urol, 28: 31-35.
    • (1995) Eur. Urol , vol.28 , pp. 31-35
    • Shekarriz, M.1    Dewire, D.M.2    Thomas Jr., A.J.3    Agarwal, A.4
  • 106
    • 0036107443 scopus 로고    scopus 로고
    • Detection of apoptotic alterations in sperm in subfertile patients and their correlations with sperm quality
    • Shen, H.M., J. Dai, S.E. Chia, A. Lim and C.N. Ong, 2002. Detection of apoptotic alterations in sperm in subfertile patients and their correlations with sperm quality. HumanReprod, 17: 1266-1273.
    • (2002) HumanReprod , vol.17 , pp. 1266-1273
    • Shen, H.M.1    Dai, J.2    Chia, S.E.3    Lim, A.4    Ong, C.N.5
  • 107
    • 0345732108 scopus 로고    scopus 로고
    • Role of oxidative stress and antioxidants in and rology and assisted reproductive technology
    • Sikka, S.C., 2004. Role of oxidative stress and antioxidants in and rology and assisted reproductive technology. J. Androl, 25: 5-18.
    • (2004) J. Androl , vol.25 , pp. 5-18
    • Sikka, S.C.1
  • 108
    • 0346849777 scopus 로고    scopus 로고
    • Effects of age on DNA double-str and breaks and apoptosis in human sperm
    • Singh, N.P., C.H. Muller and R.E. Berger, 2003. Effects of age on DNA double-str and breaks and apoptosis in human sperm. Fertil. Steril, 80: 1420-1430.
    • (2003) Fertil. Steril , vol.80 , pp. 1420-1430
    • Singh, N.P.1    Muller, C.H.2    Berger, R.E.3
  • 109
    • 0033022705 scopus 로고    scopus 로고
    • Hormonal and genetic control of germ cell apoptosis in the testis
    • Sinha-Hikim, A.P. and R.S. Swerdloff, 1999. Hormonal and genetic control of germ cell apoptosis in the testis. Rev. Reprod., 4: 38-47.
    • (1999) Rev. Reprod , vol.4 , pp. 38-47
    • Sinha-Hikim, A.P.1    Swerdloff, R.S.2
  • 110
    • 33645292883 scopus 로고    scopus 로고
    • Increased sperm DNA damage in patients with varicocele: Relationship with seminal oxidative stress
    • Smith, R., H. Kaune, D. Parodi, M. Madariaga, R. Rios, I. Morales and A. Castro, 2006. Increased sperm DNA damage in patients with varicocele: Relationship with seminal oxidative stress. Human Reprod, 21: 986-993.
    • (2006) Human Reprod , vol.21 , pp. 986-993
    • Smith, R.1    Kaune, H.2    Parodi, D.3    Madariaga, M.4    Rios, R.5    Morales, I.6    Castro, A.7
  • 111
    • 34247556438 scopus 로고    scopus 로고
    • Extent of sperm DNA damage in spermatozoa from men examined for infertility: Relationship with oxidative stress
    • Smith, G.R., G.H. Kaune, CD. Parodi, A.M. Madariaga, D.I. Morales, S.R. Rios and G.A. Castro, 2007. Extent of sperm DNA damage in spermatozoa from men examined for infertility: Relationship with oxidative stress. Rev. Med. Chil., 135: 279-286.
    • (2007) Rev. Med. Chil , vol.135 , pp. 279-286
    • Smith, G.R.1    Kaune, G.H.2    Parodi, C.D.3    Madariaga, A.M.4    Morales, D.I.5    Rios, S.R.6    Castro, G.A.7
  • 112
    • 0035995241 scopus 로고    scopus 로고
    • Can mitochondrial DNA mutations cause sperm dysfunction?
    • Spiropoulos, J., D.M. Turnbull and P.F. Chinnery, 2002. Can mitochondrial DNA mutations cause sperm dysfunction?. Mol. Human Reprod., 8: 719-721.
    • (2002) Mol. Human Reprod , vol.8 , pp. 719-721
    • Spiropoulos, J.1    Turnbull, D.M.2    Chinnery, P.F.3
  • 113
    • 0031045420 scopus 로고    scopus 로고
    • Detection of deoxyribonucleic acid fragmentation in human sperm: Correlation with fertilization in vitro
    • Sun, J.G., A. Jurisicova and R.F. Casper, 1997. Detection of deoxyribonucleic acid fragmentation in human sperm: correlation with fertilization in vitro. Biol. Reprod., 56: 602-607.
    • (1997) Biol. Reprod , vol.56 , pp. 602-607
    • Sun, J.G.1    Jurisicova, A.2    Casper, R.F.3
  • 114
    • 0026768569 scopus 로고
    • Is melonaldehyde a valuable indicator of lipid peroxidation?
    • Taourel, D.B., M.C. Guerin and J. Torreilles, 1992. Is melonaldehyde a valuable indicator of lipid peroxidation?. Biochem. Pharmacol., 44: 985-988.
    • (1992) Biochem. Pharmacol , vol.44 , pp. 985-988
    • Taourel, D.B.1    Guerin, M.C.2    Torreilles, J.3
  • 115
    • 68949206432 scopus 로고    scopus 로고
    • Cryopreservation-induced human sperm DNA damage is predominantly mediated by oxidative stress rather than apoptosis
    • Thomson, L.K., S.D. Fleming, R.J. Aitken, G.N. de Iuliis, J.A. Zieschang and A.M. Clark, 2009. Cryopreservation-induced human sperm DNA damage is predominantly mediated by oxidative stress rather than apoptosis. Human Reprod, 24: 2061-2070.
    • (2009) Human Reprod , vol.24 , pp. 2061-2070
    • Thomson, L.K.1    Fleming, S.D.2    Aitken, R.J.3    de Iuliis, G.N.4    Zieschang, J.A.5    Clark, A.M.6
  • 116
    • 0031822760 scopus 로고    scopus 로고
    • Oxidative damage to DNA in human spermatozoa does not preclude pronucleous formation at intracytoplamic sperm injection
    • Twigg, J., D.S. Irvine and R.J. Aitken, 1998. Oxidative damage to DNA in human spermatozoa does not preclude pronucleous formation at intracytoplamic sperm injection. Human Reprod., 13: 1864-1871.
    • (1998) Human Reprod , vol.13 , pp. 1864-1871
    • Twigg, J.1    Irvine, D.S.2    Aitken, R.J.3
  • 119
    • 35048877043 scopus 로고    scopus 로고
    • Diabetes, obesity and metabolism
    • Vincent, H., 2007. Diabetes, obesity and metabolism. Clin. Chem., 9: 813-839.
    • (2007) Clin. Chem , vol.9 , pp. 813-839
    • Vincent, H.1
  • 120
    • 0029870387 scopus 로고    scopus 로고
    • Cigarette smoking and semen quality
    • Vine, M.F., C.K.J.P.C. Tse Hu and K.Y. Truong, 1996. Cigarette smoking and semen quality. Fert. Ster., 65: 835-842.
    • (1996) Fert. Ster , vol.65 , pp. 835-842
    • Vine, M.F.1    Hu, C.K.J.P.C.T.2    Truong, K.Y.3
  • 121
    • 33750370804 scopus 로고    scopus 로고
    • Underst and Ing the Molecular Causes of Parkinsons's Disease
    • Wood-Kaczmar, A., S. Gandhi and W.N. Wood, 2006. Underst and ing the molecular causes of parkinsons's disease. Trends Mol. Med., 12: 521-528.
    • (2006) Trends Mol. Med. , vol.12 , pp. 521-528
    • Wood-Kaczmar, A.1    Gandhi, S.2    Wood, W.N.3
  • 122
    • 0026642535 scopus 로고
    • The influence of varicocele on parameters of fertility in a large group of men presenting to infertility clinics
    • World Health Organization
    • World Health Organization, 1992. The influence of varicocele on parameters of fertility in a large group of men presenting to infertility clinics. Fertil. Steril., 57: 1289-1293.
    • (1992) Fertil. Steril , vol.57 , pp. 1289-1293
  • 124
    • 0019225636 scopus 로고
    • Cell death: The significance of apoptosis
    • Wyllie, A.H., J.F. Kerr and A.R. Currie, 1980. Cell death: The significance of apoptosis. Int. Rev. Cytol., 68: 251-306.
    • (1980) Int. Rev. Cytol , vol.68 , pp. 251-306
    • Wyllie, A.H.1    Kerr, J.F.2    Currie, A.R.3
  • 125
    • 0031919178 scopus 로고    scopus 로고
    • An electron microscope study of the axonemal ultrastructure in human spermatozoa from male smokers and nonsmokers
    • Zoas, P.M., J.R. Correa, C.S. Karagounis, A. Ahparaki, C. Phorouglu and C.L. Hicks, 1998. An electron microscope study of the axonemal ultrastructure in human spermatozoa from male smokers and nonsmokers. Fertil. Steril., 69: 430-434.
    • (1998) Fertil. Steril , vol.69 , pp. 430-434
    • Zoas, P.M.1    Correa, J.R.2    Karagounis, C.S.3    Ahparaki, A.4    Phorouglu, C.5    Hicks, C.L.6


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