Caspase activation in human spermatozoa in response to physiological and pathological stimuli

Fertility and Sterility

Volumn 83, Issue 4 SUPPL., 2005, Pages 1106-1112

  Grunewald, Sonja ^a   Paasch, Uwe ^a   Said, Tamer M ^b   Sharma, Rakesh K ^b   Glander, Hans Juergen ^a   Agarwal, Ashok ^b  

^a UNIVERSITY OF LEIPZIG   (Germany)

^b LERNER RESEARCH INSTITUTE   (United States)

Author keywords

Apoptosis pathways; Caspase activation; Ejaculated spermatozoa; Oxidative stress

Indexed keywords

BETULIC ACID; CASPASE; CASPASE 3; CASPASE 8; CASPASE 9; FAS ASSOCIATED DEATH DOMAIN PROTEIN; INTERLEUKIN 1BETA CONVERTING ENZYME;

APOPTOSIS; ARTICLE; CELL STIMULATION; CONTROLLED STUDY; ENZYME ACTIVATION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; INCUBATION TIME; MALE; MITOCHONDRIAL MEMBRANE; NORMAL HUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; SPERMATOZOON; SPERMATOZOON CAPACITATION; SPERMATOZOON MATURATION;

EID: 17444364399     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2004.12.011     Document Type: Article

References (55)

1. J.F.R. Kerr, A.H. Wyllie, A.R. Currie Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics Br J Cancer 26 1972 239 257
2. B. Baccetti, G. Collodel, P. Piomboni Apoptosis in human ejaculated sperm cells (notulae seminologicae 9) J Submicrosc Cytol Pathol 28 1996 587 596
3. W. Gorczyca, F. Traganos, H. Jesionowska, Z. Darzynkiewicz Presence of DNA strand breaks and increased sensitivity of DNA in situ to denaturation in abnormal human sperm cells: analogy to apoptosis of somatic cells Exp Cell Res 207 1993 202 205
4. T. Vorup-Jensen, T. Hjort, J.V. Abraham-Peskir, P. Guttmann, J.C. Jensenius, E. Uggerhoj X-ray microscopy of human spermatozoa shows change of mitochondrial morphology after capacitation Hum Reprod 14 1999 880 884
5. J.C. Rockett, F.L. Mapp, J.B. Garges, J.C. Luft, C. Mori, D.J. Dix Effects of hyperthermia on spermatogenesis, apoptosis, gene expression, and fertility in adult male mice Biol Reprod 65 2001 229 239
6. J.M. Kim, S.R. Ghosh, A.C. Weil, B.R. Zirkin Caspase-3 and caspase-activated deoxyribonuclease are associated with testicular germ cell apoptosis resulting from reduced intratesticular testosterone Endocrinology 142 2001 3809 3816
7. T. Shikone, H. Billig, A.J. Hsueh Experimentally induced cryptorchidism increases apoptosis in rat testis Biol Reprod 51 1994 865 872
8. J.L. Marmar The pathophysiology of varicoceles in the light of current molecular and genetic information Hum Reprod Update 7 2001 461 472
9. D. Sakkas, E. Mariethoz, J.C. St John Abnormal sperm parameters in humans are indicative of an abortive apoptotic mechanism linked to the Fas-mediated pathway Exp Cell Res 251 1999 350 355
10. H.M. Shen, J. Dai, S.E. Chia, A. Lim, C.N. Ong Detection of apoptotic alterations in sperm in subfertile patients and their correlations with sperm quality Hum Reprod 17 2002 1266 1273
11. G.J. Oosterhuis, A.B. Mulder, E. Kalsbeek-Batenburg, C.B. Lambalk, J. Schoemaker, I. Vermes Measuring apoptosis in human spermatozoa: a biological assay for semen quality? Fertil Steril 74 2000 245 250
12. J. Tesarik, E. Greco, P. Cohen-Bacrie, C. Mendoza Germ cell apoptosis in men with complete and incomplete spermiogenesis failure Mol Hum Reprod 4 1998 757 762
13. Paasch U, Grunewald S, Wuendrich K, Glander HJ. Caspases are associated with apoptosis in human ejaculated spermatozoa and in spermatogenesis. In: Robaire B, Chemes H, Morales CR, eds. Andrology in the 21st century. Proceedings of the VIIth International Congress of Andrology, Montreal, Quebec, Canada, 2001 June 15-19; Bologna: Medimond International Proceedings, 2001:59-64.
14. M.H. Moustafa, R.K. Sharma, J. Thornton, E. Mascha, M.A. Abdel-Hafez, A.J. Thomas Relationship between ROS production, apoptosis and DNA denaturation in spermatozoa from patients examined for infertility Hum Reprod 19 2004 129 138
15. G.M. Cohen Caspases: the executioners of apoptosis Biochem J 326 1997 1 16
16. G.S. Salvesen, V.M. Dixit Caspases: intracellular signaling by proteolysis Cell 91 1997 443 446
17. T. Suda, T. Takahashi, P. Golstein, S. Nagata Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family Cell 75 1993 1169 1178
18. K. Schulze-Osthoff, D. Ferrari, M. Los, S. Wesselborg, M.E. Peter Apoptosis signaling by death receptors Eur J Biochem 254 1998 439 459
19. S. Nagata, P. Golstein The Fas death factor Science 267 1995 1449 1456
20. I. Budihardjo, H. Oliver, M. Lutter, X. Luo, X. Wang Biochemical pathways of caspase activation during apoptosis Ann Rev Cell Dev Biol 15 1999 269 290
21. P. Costantini, E. Jacotot, D. Decaudin, G. Kroemer Mitochondrion as a novel target of anticancer chemotherapy J Natl Cancer Inst 92 2000 1042 1053
22. S. Fulda, I. Jeremias, H.H. Steiner, T. Pietsch, K.M. Debatin Betulinic acid: a new cytotoxic agent against malignant brain-tumor cells Int J Cancer 82 1999 435 441
23. E. Selzer, E. Pimentel, V. Wacheck, W. Schlegel, H. Pehamberger, B. Jansen Effects of betulinic acid alone and in combination with irradiation in human melanoma cells J Invest Dermatol 114 2000 935 940
24. X. Wang, R.K. Sharma, A. Gupta, V. George, A.J. Thomas, T. Falcone Alterations in mitochondria membrane potential and oxidative stress in infertile men: a prospective observational study Fertil Steril 80 Suppl 2 2003 844 850
25. U. Paasch, A. Agarwal, A.K. Gupta, R.K. Sharma, S. Grunewald, A.J. Thomas Jr Apoptosis signal transduction and the maturity status of human spermatozoa Ann NY Acad Sci 1010 2003 486 489
26. A. Dumont, S.P. Hehner, T.G. Hofmann, M. Ueffing, W. Droge, M.L. Schmitz Hydrogen peroxide-induced apoptosis is CD95-independent, requires the release of mitochondria-derived reactive oxygen species and the activation of NF-kappaB Oncogene 18 1999 747 757
27. K.J. De Vries, T. Wiedmer, P.J. Sims, B.M. Gadella Caspase-independent exposure of aminophospholipids and tyrosine phosphorylation in bicarbonate responsive human sperm cells Biol Reprod 68 2003 2122 2134
28. S. Oehninger, M. Morshedi, S.L. Weng, S. Taylor, H. Duran, S. Beebe Presence and significance of somatic cell apoptosis markers in human ejaculated spermatozoa Reprod Biomed Online 7 2003 469 476
29. B.M. Gadella, R.A. Harrison Capacitation induces cyclic adenosine 3′,5′-monophosphate-dependent, but apoptosis-unrelated, exposure of aminophospholipids at the apical head plasma membrane of boar sperm cells Biol Reprod 67 2002 340 350
30. World Health Organization WHO laboratory manual for the examination of human semen and sperm-cervical mucus interaction 1999 Cambridge University Press Cambridge
31. O.I. Aruoma, B. Halliwell, B.M. Hoey, J. Butler The antioxidant action of taurine, hypotaurine and their metabolic precursors Biochem J 256 1988 251 255
32. P.G. Ekert, J. Silke, D.L. Vaux Caspase inhibitors Cell Death Diff 6 1999 1081 1086
33. E. Bedner, P. Smolewski, P. Amstad, Z. Darzynkiewicz Activation of caspases measured in situ by binding of fluorochrome-labeled inhibitors of caspases (FLICA): correlation with DNA fragmentation Exp Cell Res 259 2000 308 313
34. U. Paasch, S. Grunewald, G. Fitzl, H.J. Glander Deterioration of plasma membrane is associated with activation of caspases in human spermatozoa J Androl 24 2003 246 252
35. C. Bohring, E. Krause, B. Habermann, W. Krause Isolation and identification of sperm membrane antigens recognized by antisperm antibodies, and their possible role in immunological infertility disease Mol Hum Reprod 7 2001 113 118
36. S.L. Weng, S.L. Taylor, M. Morshedi, A. Schuffner, E.H. Duran, S. Beebe Caspase activity and apoptotic markers in ejaculated human sperm Mol Hum Reprod 8 2002 984 991
37. X. Wang, R.K. Sharma, S.C. Sikka, A.J. Thomas Jr, T. Falcone, A. Agarwal Oxidative stress is associated with increased apoptosis leading to spermatozoa DNA damage in patients with male factor infertility Fertil Steril 80 2003 531 535
38. H. Tanaka, M. Fujisawa, H. Tanaka, H. Okada, S. Kamidono Apoptosis-related proteins in the testes of infertile men with varicocele BJU Int 89 2002 905 909
39. J. Blanco-Rodriguez, C. Martinez-Garcia Apoptosis is physiologically restricted to a specialized cytoplasmic compartment in rat spermatids Biol Reprod 61 1999 1541 1547
40. J. Lee, J.H. Richburg, S.C. Younkin, K. Boekelheide The Fas system is a key regulator of germ cell apoptosis in the testis Endocrinology 138 1997 2081 2088
41. V. Pentikainen, K. Erkkila, L. Dunkel Fas regulates germ cell apoptosis in the human testis in vitro Am J Physiol 276 1999 E310 E316
42. S. Grunewald, U. Paasch, H.J. Glander Enrichment of non-apoptotic human spermatozoa after cryopreservation by immunomagnetic cell sorting Cell Tiss Banking 2 2001 127 133
43. A. Sugihara, S. Saiki, M. Tsuji, T. Tsujimura, Y. Nakata, A. Kubota Expression of Fas and Fas ligand in the testes and testicular germ cell tumors: an immunohistochemical study Anticancer Res 17 1997 3861 3865
44. A. D'Alessio, A. Riccioli, P. Lauretti, F. Padula, B. Muciaccia, P. De Cesaris Testicular FasL is expressed by sperm cells Proc Natl Acad Sci USA 98 2001 3316 3321
45. J.H. Richburg, A. Nanez, L.R. Williams, M.E. Embree, K. Boekelheide Sensitivity of testicular germ cells to toxicant-induced apoptosis in gld mice that express a nonfunctional form of Fas ligand Endocrinology 141 2000 787 793
46. R.J. Aitken, C. Krausz Oxidative stress, DNA damage and the Y chromosome Reproduction 122 2001 497 506
47. R.A. Saleh, A. Agarwal, D.R. Nelson, E.A. Nada, M.H. El Tonsy, J.G. Alvarez Increased sperm nuclear DNA damage in normozoospermic infertile men: a prospective study Fertil Steril 78 2002 313 318
48. S. Lamond, M. Watkinson, T. Rutherford, K. Laing, A. Whiting, A. Smallwood Gene-specific chromatin damage in human spermatozoa can be blocked by antioxidants that target mitochondria Reprod Biomed Online 7 2003 407 418
49. M. Leist, B. Single, H. Naumann, E. Fava, B. Simon, S. Kuhnle Inhibition of mitochondrial ATP generation by nitric oxide switches apoptosis to necrosis Exp Cell Res 249 1999 396 403
50. R.M. Friedlander Apoptosis and caspases in neurodegenerative diseases N Engl J Med 348 2003 1365 1375
51. C. Cande, F. Cecconi, P. Dessen, G. Kroemer Apoptosis-inducing factor (AIF): key to the conserved caspase-independent pathways of cell death? J Cell Sci 115 2002 4727 4734
52. K.K. Wang, R. Posmantur, R. Nadimpalli, R. Nath, P. Mohan, R.A. Nixon Caspase-mediated fragmentation of calpain inhibitor protein calpastatin during apoptosis Arch Biochem Biophys 356 1998 187 196
53. K. Shiraishi, K. Naito, K. Yoshida Inhibition of calpain but not caspase protects the testis against injury after experimental testicular torsion of Rat Biol Reprod 63 2000 1538 1548
54. K.K. Wang Calpain and caspase: can you tell the difference? Trends Neurosci 23 2000 20 26
55. A. Schuffner, M. Morshedi, D. Vaamonde, E.H. Duran, S. Oehninger Effect of different incubation conditions on phosphatidylserine externalization and motion parameters of purified fractions of highly motile human spermatozoa J Androl 23 2002 194 201