Neuroprotective efficacy and therapeutic window of Forsythoside B: In a rat model of cerebral ischemia and reperfusion injury

European Journal of Pharmacology

Volumn 640, Issue 1-3, 2010, Pages 75-81

  Jiang, Wang Lin ^a   Tian, Jing Wei ^a   Fu, Feng Hua ^a   Zhu, Hai Bo ^b   Hou, Jian ^b  

^a YANTAI UNIVERSITY   (China)

^b State Key Laboratory of Long acting and Targeting Drug Delivery Technologies (Luye Pharma Group Ltd)   (China)

Author keywords

Cerebral ischemia; Forsythoside B; Inflammatory response; Nuclear factor kappaB

Indexed keywords

EVANS BLUE; FORSYTHOSIDE B; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MYELOPEROXIDASE; PLANT GLYCOSIDE; UNCLASSIFIED DRUG; ANTIINFLAMMATORY AGENT; CAFFEIC ACID DERIVATIVE; CELL NUCLEUS ANTIGEN; GLUCOSIDE; GLYCOSIDE; NERVE PROTEIN; NEUN PROTEIN, RAT; NEUROPROTECTIVE AGENT; PEROXIDASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BOLUS INJECTION; BRAIN EDEMA; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; COMPETITIVE INHIBITION; CONTROLLED STUDY; DRUG EFFICACY; DRUG MECHANISM; ENZYME ACTIVITY; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; INFLAMMATION; LEUKOCYTE; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NEUROPROTECTION; NONHUMAN; POLYMORPHONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REPERFUSION INJURY; SPRAGUE DAWLEY RAT; ANIMAL; BRAIN INFARCTION; COMPLICATION; CONTRAST MEDIUM EXTRAVASATION; DISEASE MODEL; DRUG EFFECTS; IMMUNOLOGY; METABOLISM; NERVE CELL; PATHOLOGY; TOXICITY;

ANIMALS; ANTI-INFLAMMATORY AGENTS; ANTIGENS, NUCLEAR; BRAIN INFARCTION; BRAIN ISCHEMIA; CAFFEIC ACIDS; DISEASE MODELS, ANIMAL; EVANS BLUE; EXTRAVASATION OF DIAGNOSTIC AND THERAPEUTIC MATERIALS; GLUCOSIDES; GLYCOSIDES; LEUKOCYTES; MALE; NERVE TISSUE PROTEINS; NEURONS; NEUROPROTECTIVE AGENTS; NF-KAPPA B; PEROXIDASE; RATS; RATS, SPRAGUE-DAWLEY; REPERFUSION INJURY;

EID: 77953810867     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2010.04.055     Document Type: Article

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