Effect of aminoguanidine on post-ischemic brain edema in transient model of focal cerebral ischemia

Brain Research

Volumn 1170, Issue SUPPL.: COMPLETE, 2007, Pages 97-102

  Vakili, Abedin ^a,b   Hosseinzadeh, Fezzeh ^b   Sadogh, Toktam ^b  

^a University of Medical Sciences   (Iran)

^b SEMNAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Aminoguanidine; BBB permeability; Brain edema; Rat; Transient focal cerebral ischemic

Indexed keywords

AMINOGUANIDINE; CHLORAL HYDRATE; EVANS BLUE; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN EDEMA; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; BRAIN PERFUSION; CONTROLLED STUDY; DRUG DOSE COMPARISON; DRUG MECHANISM; EXTRAVASATION; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NONHUMAN; PERMEABILITY; PRIORITY JOURNAL; RAT; TRAUMATIC BRAIN INJURY;

ANIMALS; BLOOD-BRAIN BARRIER; BRAIN EDEMA; BRAIN INFARCTION; CEREBRAL ARTERIES; COLORING AGENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; ENZYME INHIBITORS; EVANS BLUE; GUANIDINES; INFARCTION, MIDDLE CEREBRAL ARTERY; ISCHEMIC ATTACK, TRANSIENT; MALE; RATS; RATS, WISTAR; REPERFUSION INJURY; TIME FACTORS; TREATMENT OUTCOME;

RATTUS;

EID: 34548471968     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2007.07.016     Document Type: Article

References (38)

1. Abdel-Rahman E., and Bolto WK. Pimagedin: a novel therapy for diabetic nephropathy. Expert Opin. Investig. Drugs 11 (2002) 565-574
2. Cash D., Beech J.S., Rayne R.C., Bath P.M., Meldrum B.S., and Williams S.C. Neuroprotective effect of aminoguanidine on transient focal ischaemia in the rat brain. Brain Res. 29 (2001) 91-103
3. Chan P.H. Oxygen radical in focal cerebral ischemia. Brain Pathol. 4 (1994) 59-65
4. Cockroft K.M., Meistrell M., Zimmerman G.A., Risucci D., Bloom O., Cerami A., and Tracey K.J. Cerebroprotective effects of aminoguanidine in a rodent model of stroke. Stroke 27 (1996) 1393-1398
5. Danielisova V., Nemethova M., and Burda J. The protective effect of aminoguanidine on cerebral ischemic damage in the rat brain. Physiol. Res. 53 (2004) 533-540
6. Ding-Zhou L., Marchand-Verrecchia C., Croci N., Plotkine M., and Margaill I. l-NAME reduces infarction, neurological deficit and blood-brain barrier disruption following cerebral ischemia in mice. Eur. J. Pharmacol. 457 (2002) 137-146
7. Giardino I., Fard A.K., Hatchell D.L., and Brownlee M. Aminoguanidine inhibits reactive oxygen species formation, lipid peroxidation, and oxidant-induced apoptosis. Diabetes 47 (1998) 1114-1120
8. Hammes HP., Martin S., Federlin K., Geisen K., and Brownlee M. Aminoguanidine treatment inhibits the development of experimental diabetic retinopathy. Proc. Natl. Acad. Sci. U. S. A. 88 (1991) 11555-11558
9. Hatashita S., and Hoff J.T. Brain edema and cerebrovascular permeability during cerebral ischemia in rats. Stroke 21 (1990) 581-588
10. Huang Z., Huang P.L., Ma J., Meng W., Ayata C., Fishman M.C., and Moskowitz M.A. Enlarged infarcts in endothelial nitric oxide synthase knockout mice are attenuated by nitro-l-arginine. J. Cereb. Blood Flow Metab. 16 (1996) 981-987
11. Iadecola C., Zhang F., and Xu X. Inhibition of inducible nitric oxide synthase ameliorates cerebral ischemic damage. Am. J. Physiol. 268 (1995) R286-R292
12. Iadecola C., Zhang F., Xu X., Casey R., and Ross M.E. Inducible nitric oxide synthase gene expression in brain following focal cerebral ischemia. J. Cereb. Blood Flow Metab. 15 (1995) 378-384
13. Jones N.C., Constantin D., Gibson C.L., Prior M.J., Morris P.G., Marsden C.A., and Murphy S.A. Detrimental role for nitric oxide synthase-2 in the pathology resulting from acute cerebral injury. J. Neuropathol Exp. Neurol. 63 (2004) 708-720
14. Kazachkov, M., Chen, K., Babiy, S., Yu, PH., in press. Evidence for in vivo scavenging by aminoguanidine of formaldehyde produced via SSAO-mediated deamination. J Pharmacol Exp Ther. doi:10.1124/jpet.107.124123.
15. Kondo T., Reaume A.G., Huang T.T., Carlson E., Murakami K., Chen S.F., Hoffman E.K., Scott R.W., Epstein C.J., and Chan P.H. Reduction of CuZn-superoxide dismutase activity exacerbates neuronal cell injury and edema formation after transient focal cerebral ischemia. J. Neurosci. 17 (1997) 4180-4189
16. Kucuk M., Kaya M., Kalayci R., Cimen V., Kudat H., Arican N., Elmas I., and Korkut F. Effects of losartan on the blood-brain barrier permeability in long-term nitric oxide blockade-induced hypertensive rats. Life Sci. 12 (2002) 496-937
17. Laszlo F., Evans S.M., and Whittle B.J.R. Aminoguanidine inhibits both constitutive and inducible nitric oxide synthase isoforms in rat intestinal microvasculature in vivo. Eur. J. Pharmacol. 272 (1995) 169-175
18. Lin T.N., He Y.Y., Wu G., Khan M., and Hsu C.Y. Effect of brain edema on infarct volume in a focal cerebral ischemia model in rats. Stroke 24 (1993) 117-121
19. Louin G., Marchand-Verrecchia C., Palmier B., Plotkine M., and Jafarian-Tehrani M. Selective inhibition of inducible nitric oxide synthase reduces neurological deficit but not cerebral edema following traumatic brain injury. Neuropharmacology 50 (2006) 182-190
20. Nagayama M., Zhang F., and Iadecola C. Delayed treatment with aminoguanidine decreases focal cerebral ischemic damage and enhances neurologic recovery in rats. J. Cereb. Blood Flow Metab. 18 (1998) 1107-1113
21. Nelson C.W., Wei E.P., Povlishock J.T., Kontos H.A., and Moskowitz M.A. Oxygen radicals in cerebral ischemia. Am. J. Physiol. 263 (1992) H1356-H1362
22. Nilsson BO.l. Biological effects of aminoguanidine: an update. Inflamm. Res. 48 (1999) 509-515
23. Shapira Y., Shohami E., Sidi A., Soffer D., Freeman S., and Cotev S. Experimental closed head injury in rats: mechanical, pathophysiologic, and neurologic properties. Crit. Care Med. 16 (1988) 258-265
24. Slivka A., Murphy E., and Horrocks L. Cerebral edema after temporary and permanent middle cerebral artery occlusion in the rat. Stroke 26 (1995) 1061-1065
25. Sugimoto K., and Iadecola C. Effects of aminoguanidine on cerebral ischemia in mice: comparison between mice with and without inducible nitric oxide synthase gene. Neurosci. Lett. 331 (2002) 25-28
26. Swanson R.A., Morton M.T., Tsao-Wu G., Savalos R.A., Davidson C., and Sharp F.R. Semiautomated method for measuring brain infarct volume. J. Cereb. Blood Flow Metab. 10 (1990) 290-293
27. Taguchi T., Miyoshi H., Sugiura M., Takeuchi M., Yanagisawa K., Watanabe Y., Miwa I., and Makita Z. A glycation inhibitor, aminoguanidine and pyridoxal adduct, suppresses the development of diabetic nephropathy. Int. Congr. Ser. 1245 (2002) 435-437
28. Takizawa S., Fukuyama N., Hirabayashi H., Nakazawa H., and Shinohara Y. Dynamics of nitrotyrosine formation and decay in rat brain during focal ischemia-reperfusion. J. Cereb. Blood Flow Metab. 19 (1999) 667-672
29. Vakili A., Kataoka H., and Plesnila N. Role of arginine vasopressin V1 and V2 receptors for brain damage after transient focal cerebral ischemia. J. Cereb. Blood Flow Metab. 25 (2005) 1012-1019
30. Vakili A., Nekoeian A.A., and Dehghani G.A. Aminoguanidine reduces infarct volume and improve neurological dysfunction in rat model focal cerebral ischemia. DARU 14 (2006) 31-36
31. Vakili A., and Zahedi Khorasani M. Post-ischemic treatment of pentoxifyline reduces cortical not striatal infarct volume in transient model of focal cerebral ischemia in rat. Brain Res. 1144 (2007) 186-191
32. Yagihashi S., Kamijo M., Baba M., Yagihashi N., and Nagai K. Effect of aminoguanidine on functional and structural abnormalities in peripheral nerve of STZ-induced diabetic rats. Diabetes 41 (1992) 47-52
33. Yang GY., Gong C., Qin Z., Liu XH., and Lorris Betz A. Tumor necrosis factor alpha expression produces increased blood-brain barrier permeability following temporary focal cerebral ischemia in mice. Brain Res. Mol. Brain Res. 69 (1999) 135-143
34. Yildiz G., Demiryurek A.T., Sahin-Erdemli I., and Kanzik I. Comparison of antioxidant activities of aminoguanidine, methylguanidine and guanidine by luminol-enhanced chemiluminescence. Br. J. Pharmacol. 124 (1998) 905-910
35. Zhang F., and Iadecola C. Temporal characteristics of the protective effect of aminoguanidine on cerebral ischemic damage. Brain Res. 802 (1998) 104-110
36. Zhang F., Robyn M., Casey B.S., Ross M.E., and Iadecola C. Aminoguanidine ameliorates and l-arginine worsens brain damage from intraluminal middle cerebral artery occlusion. Stroke 27 (1996) 317-323
37. Zhang X.M., and Ellis E.F. Superoxide dismutase reduces permeability and edema induced by hypertension in rats. Am. J. Physiol. 259 (1990) H497-H503
38. Zimmerman G.A., Meistrell M.I., Bloom O., Cockroft K.M., Bianchi M., Risucci D., Broome J., Farmer P., Cerami A., Vlassara H., and Tracey K.J. Neurotoxicity of advanced glycation endproducts during focal stroke and neuroprotective effects of aminoguanidine. Proc. Natl. Acad. Sci. U. S. A. 92 (1995) 3744-3774