-
1
-
-
37649010665
-
Microfluidics for drug discovery and development: From target selection to product lifecycle management
-
Kang L, Chung BG, Langer R, Khademhosseini A. Microfluidics for drug discovery and development: from target selection to product lifecycle management. Drug Discov Today 2008;13:1-13
-
(2008)
Drug Discov Today
, vol.13
, pp. 1-13
-
-
Kang, L.1
Chung, B.G.2
Langer, R.3
Khademhosseini, A.4
-
2
-
-
33644777646
-
Lab-on-a-chip: Microfluidics in drug discovery
-
Dittrich P, Manz A. Lab-on-a-chip: microfluidics in drug discovery. Nat Rev 2006;5:210-218
-
(2006)
Nat Rev
, vol.5
, pp. 210-218
-
-
Dittrich, P.1
Manz, A.2
-
3
-
-
33845342557
-
Microfluidic digital PCR enables multigene analysis of individual environmental bacteria
-
Ottesen EA, Hong JW, Quake SR, Leadbetter JR. Microfluidic digital PCR enables multigene analysis of individual environmental bacteria. Science 2006;314:41464-41467
-
(2006)
Science
, vol.314
, pp. 41464-41467
-
-
Ottesen, E.A.1
Hong, J.W.2
Quake, S.R.3
Leadbetter, J.R.4
-
4
-
-
0034908917
-
Microfluidics-downsizing large-scale biology
-
Mitchell P. Microfluidics-downsizing large-scale biology. Nat Biotechnol 2001;19:717-721
-
(2001)
Nat Biotechnol
, vol.19
, pp. 717-721
-
-
Mitchell, P.1
-
6
-
-
33745792813
-
Pharmacokinetic-pharmacodynamic modelling: History and perspectives
-
Csajka C, Verotta D. Pharmacokinetic-pharmacodynamic modelling: history and perspectives. J Pharmacokinet Pharmacodyn 2006;33:227-279
-
(2006)
J Pharmacokinet Pharmacodyn
, vol.33
, pp. 227-279
-
-
Csajka, C.1
Verotta, D.2
-
7
-
-
0842288281
-
Microfluidic tools for high-throughput screening
-
Thorsen TA. Microfluidic tools for high-throughput screening. BioTechniques 2004;36:197-199
-
(2004)
BioTechniques
, vol.36
, pp. 197-199
-
-
Thorsen, T.A.1
-
8
-
-
36448935709
-
Versatile, fully automated, microfluidic cell culture system
-
Gómez-Sj€oberg R, Leyrat AA, Pirone DM, et al. Versatile, fully automated, microfluidic cell culture system. Anal Chem 2007;79:8557-8563
-
(2007)
Anal Chem
, vol.79
, pp. 8557-8563
-
-
Gómez-Sjoberg, R.1
Leyrat, A.A.2
Pirone, D.M.3
-
9
-
-
35348902108
-
Biological cells on microchips: New technologies and applications
-
Tanaka Y, Sato K, Shimizu T, et al. Biological cells on microchips: new technologies and applications. Biosens Bioelectron 2007;23:449-458
-
(2007)
Biosens Bioelectron
, vol.23
, pp. 449-458
-
-
Tanaka, Y.1
Sato, K.2
Shimizu, T.3
-
10
-
-
74049137840
-
Single cells as experimentation units in lab-on-a-chip devices
-
Le Gac S, van den Berg A. Single cells as experimentation units in lab-on-a-chip devices. Trends Biotechnol 2010;28:55-62
-
(2010)
Trends Biotechnol
, vol.28
, pp. 55-62
-
-
Le Gac, S.1
Van Den Berg, A.2
-
12
-
-
33847356130
-
A novel 3D mammalian cell perfusion-culture system in microfluidic channels
-
Toh YC, Zhang C, Zhang J, et al. A novel 3D mammalian cell perfusion-culture system in microfluidic channels. Lab Chip 2007;7:302-309
-
(2007)
Lab Chip
, vol.7
, pp. 302-309
-
-
Toh, Y.C.1
Zhang, C.2
Zhang, J.3
-
13
-
-
67650000887
-
Microfluidic single-cell array cytometry for the analysis of tumor apoptosis
-
Wlodkowic D, Faley S, Zagnoni M, et al. Microfluidic single-cell array cytometry for the analysis of tumor apoptosis. Anal Chem 2009;81:5517-5523
-
(2009)
Anal Chem
, vol.81
, pp. 5517-5523
-
-
Wlodkowic, D.1
Faley, S.2
Zagnoni, M.3
-
14
-
-
33750478294
-
Dynamic single cell culture array
-
Carlo DD, Wu LY, Lee LP. Dynamic single cell culture array. Lab Chip 2006;6:1445-1449
-
(2006)
Lab Chip
, vol.6
, pp. 1445-1449
-
-
Carlo, D.D.1
Wu, L.Y.2
Lee, L.P.3
-
15
-
-
1342281273
-
The integration of pharmacokinetics and pharmacodynamics: Understanding dose-response
-
Abdel-Rahman SM, Kauffman RE. The integration of pharmacokinetics and pharmacodynamics: understanding dose-response. Annu Rev Pharmacol Toxicol 2004;44:111-136
-
(2004)
Annu Rev Pharmacol Toxicol
, vol.44
, pp. 111-136
-
-
Abdel-Rahman, S.M.1
Kauffman, R.E.2
-
18
-
-
0242268611
-
Drug delivery-controlling the flow
-
Brazil M. Drug delivery-Controlling the flow. Nat Rev Drug Discov 2003;2:510
-
(2003)
Nat Rev Drug Discov
, vol.2
, pp. 510
-
-
Brazil, M.1
-
20
-
-
33646540414
-
Controlled microfluidic encapsulation of cells, proteins, and microbeads in lipid vesicles
-
Tan YC, Hettiarachchi K, Siu M, et al. Controlled microfluidic encapsulation of cells, proteins, and microbeads in lipid vesicles. J Am Chem Soc 2006;128:5656-5658
-
(2006)
J Am Chem Soc
, vol.128
, pp. 5656-5658
-
-
Tan, Y.C.1
Hettiarachchi, K.2
Siu, M.3
-
21
-
-
13444280469
-
Generation of monodisperse particles by using microfluidics: Control over size, shape, and composition
-
Xu S, Nie Z, Seo M, et al. Generation of monodisperse particles by using microfluidics: control over size, shape, and composition. Angew Chem Int Ed Engl 2005;44:724-728
-
(2005)
Angew Chem Int Ed Engl
, vol.44
, pp. 724-728
-
-
Xu, S.1
Nie, Z.2
Seo, M.3
-
22
-
-
9144257375
-
Controlled production of monodisperse double emulsions by two-step droplet breakup in microfluidic devices
-
Okushima S, Nisisako T, Torii T, Higuchi T. Controlled production of monodisperse double emulsions by two-step droplet breakup in microfluidic devices. Langmuir 2004;20:9905-9908
-
(2004)
Langmuir
, vol.20
, pp. 9905-9908
-
-
Okushima, S.1
Nisisako, T.2
Torii, T.3
Higuchi, T.4
-
24
-
-
34548316287
-
Integrated siphon-based metering and sedimentation of whole blood on a hydrophilic lab-on-a-disk
-
Steigert J, Brenner T, Grumann M, et al. Integrated siphon-based metering and sedimentation of whole blood on a hydrophilic lab-on-a-disk. Biomed Microdevices 2007;9:675-679
-
(2007)
Biomed Microdevices
, vol.9
, pp. 675-679
-
-
Steigert, J.1
Brenner, T.2
Grumann, M.3
-
25
-
-
33746558539
-
Fully integrated whole blood testing by real-time absorption measurement on a centrifugal platform
-
Steigert J, Grumann M, Brenner T, et al. Fully integrated whole blood testing by real-time absorption measurement on a centrifugal platform. Lab Chip 2006;6:1040-1044
-
(2006)
Lab Chip
, vol.6
, pp. 1040-1044
-
-
Steigert, J.1
Grumann, M.2
Brenner, T.3
-
26
-
-
33947360186
-
A capillary-based microfluidic instrument suitable for immunoaffinity chromatography
-
Peoples MC, Phillips TM, Karnes HT. A capillary-based microfluidic instrument suitable for immunoaffinity chromatography. J Chromatogr B 2007;848:200-207
-
(2007)
J Chromatogr B
, vol.848
, pp. 200-207
-
-
Peoples, M.C.1
Phillips, T.M.2
Karnes, H.T.3
-
27
-
-
33644636333
-
Gelatin based microfluidic devices for cell culture
-
Paguirigan A, Beebe DJ. Gelatin based microfluidic devices for cell culture. Lab Chip 2006;6:407-413
-
(2006)
Lab Chip
, vol.6
, pp. 407-413
-
-
Paguirigan, A.1
Beebe, D.J.2
-
28
-
-
77950863285
-
Detection of single-molecule H2O2 signalling from epidermal growth factor receptor using fluorescent single-walled carbon nanotubes
-
Jin H, Heller DA, Kalbacova M, et al. Detection of single-molecule H2O2 signalling from epidermal growth factor receptor using fluorescent single-walled carbon nanotubes. Nat Nanotechnol 2010;5:302-309
-
(2010)
Nat Nanotechnol
, vol.5
, pp. 302-309
-
-
Jin, H.1
Heller, D.A.2
Kalbacova, M.3
-
29
-
-
77953722119
-
Dielectrophoretic cell assembly of artificial liver sinusoids in a microfluidic system for use in substance screening
-
Schuette J, Angres B, Benz K, et al. Dielectrophoretic cell assembly of artificial liver sinusoids in a microfluidic system for use in substance screening. Proc MicroTAS 2009;1:1847-1849
-
(2009)
Proc MicroTAS
, vol.1
, pp. 1847-1849
-
-
Schuette, J.1
Angres, B.2
Benz, K.3
-
30
-
-
67749115964
-
Evaluation of a microfluidic based cell culture platform with primary human hepatocytes for the prediction of hepatic clearance in human
-
Chao P, Maguire T, Novik E, et al. Evaluation of a microfluidic based cell culture platform with primary human hepatocytes for the prediction of hepatic clearance in human. Biochem Pharmacol 2009;78:625-632
-
(2009)
Biochem Pharmacol
, vol.78
, pp. 625-632
-
-
Chao, P.1
Maguire, T.2
Novik, E.3
-
31
-
-
77449119885
-
A microfluidic hepatic coculture platform for cell-based drug metabolism studies
-
Novik E, Maguire TJ, Cheng CKC, Yarmush ML. A microfluidic hepatic coculture platform for cell-based drug metabolism studies. Biochem Pharmacol 2010;79:1036-1044
-
(2010)
Biochem Pharmacol
, vol.79
, pp. 1036-1044
-
-
Novik, E.1
Maguire, T.J.2
Ckc, C.3
Yarmush, M.L.4
-
32
-
-
56749156418
-
Accordion-like honeycombs for tissue engineering of cardiac anisotropy
-
Engelmayr GC, Cheng M, Bettinger CJ, et al. Accordion-like honeycombs for tissue engineering of cardiac anisotropy. Nat Mater 2008;7(12):1003-1010
-
(2008)
Nat Mater
, vol.7
, Issue.12
, pp. 1003-1010
-
-
Engelmayr, G.C.1
Cheng, M.2
Bettinger, C.J.3
-
33
-
-
33747090983
-
Control and detection of chemical reactions in microfluidic systems
-
DeMello AJ. Control and detection of chemical reactions in microfluidic systems. Nature 2006;442:394-402
-
(2006)
Nature
, vol.442
, pp. 394-402
-
-
Demello, A.J.1
-
34
-
-
5144223105
-
Systematic investigation of protein phase behavior with a microfluidic formulator
-
Hansen CL, Sommer MO, Quake SR. Systematic investigation of protein phase behavior with a microfluidic formulator. Proc Natl Acad Sci USA 2004;101(40):14431-14436
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, Issue.40
, pp. 14431-14436
-
-
Hansen, C.L.1
Sommer, M.O.2
Quake, S.R.3
-
35
-
-
75149179483
-
Microfluidic devices for cell based high throughput screening
-
Upadhyaya S, Selvaganapathy PR. Microfluidic devices for cell based high throughput screening. Lab Chip 2010;10:341-348
-
(2010)
Lab Chip
, vol.10
, pp. 341-348
-
-
Upadhyaya, S.1
Selvaganapathy, P.R.2
-
36
-
-
65549112285
-
High-throughput cellular microarray platforms: Applications in drug discovery, toxicology and stem cell research
-
Fernandes TG, Diogo MM, Clark DS, et al. High-throughput cellular microarray platforms: applications in drug discovery, toxicology and stem cell research. Trends Biotechnol 2009;27:342-349
-
(2009)
Trends Biotechnol
, vol.27
, pp. 342-349
-
-
Fernandes, T.G.1
Diogo, M.M.2
Clark, D.S.3
-
37
-
-
77951583526
-
Three-dimensional cell culture microarray for high-throughput studies of stem cell fate
-
Fernandes TG, Kwo SJ, Bal SS, et al. Three-dimensional cell culture microarray for high-throughput studies of stem cell fate. Biotechnol Bioeng 2010;106:106-118
-
(2010)
Biotechnol Bioeng
, vol.106
, pp. 106-118
-
-
Fernandes, T.G.1
Kwo, S.J.2
Bal, S.S.3
-
38
-
-
69549138236
-
Hype, hope and hubris: The quest for the killer application in microfluidics
-
Becker H. Hype, hope and hubris: the quest for the killer application in microfluidics. Lab Chip 2009;15:2119-2122
-
(2009)
Lab Chip
, vol.15
, pp. 2119-2122
-
-
Becker, H.1
-
39
-
-
2142734863
-
Microfluidic toolbox: Tools and standardization solutions for microfluidic devices for life sciences applications
-
San Jose: SPIE
-
Gärtner C, Becker H, Anton B, R€otting O. Microfluidic toolbox: tools and standardization solutions for microfluidic devices for life sciences applications. Proceedings "Microfluidics, BioMEMS, and Medical Microsystems II" Volume 5345. San Jose: SPIE, 2003. p. 159-162
-
(2003)
Proceedings "microfluidics, BioMEMS, and Medical Microsystems II"
, vol.5345
, pp. 159-162
-
-
Gärtner, C.1
Becker, H.2
Anton, B.3
Rotting, O.4
-
40
-
-
69549126224
-
Microfluidics: The great divide
-
Blow N. Microfluidics: the great divide. Nat Methods 2009;6:683-686
-
(2009)
Nat Methods
, vol.6
, pp. 683-686
-
-
Blow, N.1
-
41
-
-
0031783806
-
Miniaturization of analytical systems
-
Kricka L. Miniaturization of analytical systems. Clin Chem 1998;44:2008-2014
-
(1998)
Clin Chem
, vol.44
, pp. 2008-2014
-
-
Kricka, L.1
-
42
-
-
40049110139
-
Single-molecule detection of DNA via sequence-specific links between F1-ATPase motors and gold nanorod sensors
-
York J, Spetzler D, Xiong F, Frasch WD. Single-molecule detection of DNA via sequence-specific links between F1-ATPase motors and gold nanorod sensors. Lab Chip 2008;8:415-419
-
(2008)
Lab Chip
, vol.8
, pp. 415-419
-
-
York, J.1
Spetzler, D.2
Xiong, F.3
Frasch, W.D.4
-
43
-
-
76749092617
-
SERS as tool for the analysis of DNA-chips in a microfluidic platform
-
Strelau KK, Kretschmer R, M€oller R, et al. SERS as tool for the analysis of DNA-chips in a microfluidic platform. Anal Bioanal Chem 2010;396:1381-1384
-
(2010)
Anal Bioanal Chem
, vol.396
, pp. 1381-1384
-
-
Strelau, K.K.1
Kretschmer, R.2
Moller, R.3
-
44
-
-
54749087430
-
Electronic and optical properties of electromigrated molecular junctions
-
Ward DR, Scott GD, Keane ZK, et al. Electronic and optical properties of electromigrated molecular junctions. J Phys Condens Matter 2008;20:374118
-
(2008)
J Phys Condens Matter
, vol.20
, pp. 374118
-
-
Ward, D.R.1
Scott, G.D.2
Keane, Z.K.3
|