Dielectrophoretic cell assembly of artificial liver sinusoids in a microfluidic system for use in substance screening

Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences

Volumn , Issue , 2009, Pages 1847-1849

  Schütte, Julia ^a   Angres, Birgit ^a   Benz, Karin ^a   Freudigmann, Christian ^a   Hagmeyer, Britta ^a   Holzner, Felix ^a   Kubon, Massimo ^a   Werner, Simon ^a   Böttger, Jan ^b   Gebhardt, Rolf ^b   Becker, Holger ^c   Röhnert, Peter ^d   Stelzle, Martin ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b UNIVERSITY OF LEIPZIG   (Germany)

^c MICROFLUIDIC CHIPSHOP GMBH   (Germany)

^d KeyNeurotek AG   (Germany)

Author keywords

Cell assembly; Dielectrophoresis; Polymer chip

Indexed keywords

ARTIFICIAL ORGANS; DIELECTRIC DEVICES; ELECTROPHORESIS; ENDOTHELIAL CELLS;

CELL ASSEMBLY; DIELECTROPHORETIC; EXTRACELLULAR MATRIX PROTEIN; HYDRODYNAMIC FORCES; INTEGRATED ELECTRODES; MICRO FLUIDIC SYSTEM; POLYMER CHIPS; SUBSTANCE SCREENING;

FLUIDIC DEVICES;

EID: 77953722119     PISSN: None     EISSN: None     Source Type: Conference Proceeding    
DOI: None     Document Type: Conference Paper

References (3)

1. "The effect of three-dimensional co-culture of hepatocytes ad hepatic stellate cells on key hepatocyte functions in vitro", R.J. Thomas et al., Cells Tissues Organs, 181(2), 67-79 (2005).
2. "A microscale in vitro physiological model of the liver: predictive screens for drug metabolism and enzyme induction", A. Sivaraman et al., Curr Drug Metab, 6(6), 569-91 (2005).
3. "New hepatocyte in vitro systems for drug metabolism: metabolic capacity and recommendations for application in basic research and drug development, standard operation procedures", R. Gebhardt et al., Drug Metab Rev, 5(2-3), 145-213 (2003).