메뉴 건너뛰기




Volumn 98, Issue 3, 2010, Pages 230-244

A transcriptomics-based biological framework for studying mechanisms of endocrine disruption in small fish species

Author keywords

Endocrine; Fish; Network; Pathway; Signaling; Transcriptional

Indexed keywords

ENDOCRINE DISRUPTOR; ETHINYLESTRADIOL; FADROZOLE; FIPRONIL; FLUTAMIDE; KETOCONAZOLE; MUSCIMOL; PROCHLORAZ; PROTEIN P53; TRANSCRIPTION FACTOR; TRANSFORMING GROWTH FACTOR BETA; TRENBOLONE; TRILOSTANE; UNCLASSIFIED DRUG; VILCLOZOLIN;

EID: 77953684081     PISSN: 0166445X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.aquatox.2010.02.021     Document Type: Article
Times cited : (37)

References (73)
  • 2
    • 33646384574 scopus 로고    scopus 로고
    • The fathead minnow in aquatic toxicology: past, present and future
    • Ankley G.T., Villeneuve D.L. The fathead minnow in aquatic toxicology: past, present and future. Aquat. Toxicol. 2006, 78:91-102.
    • (2006) Aquat. Toxicol. , vol.78 , pp. 91-102
    • Ankley, G.T.1    Villeneuve, D.L.2
  • 6
    • 63849083754 scopus 로고    scopus 로고
    • Inferring gene networks: dream or nightmare? Part 1: challenges 1 and 3
    • Baralla A., Mentzen W.I., de la Fuente A. Inferring gene networks: dream or nightmare? Part 1: challenges 1 and 3. Ann. N. Y. Acad. Sci. 2009, 1158:246-256.
    • (2009) Ann. N. Y. Acad. Sci. , vol.1158 , pp. 246-256
    • Baralla, A.1    Mentzen, W.I.2    de la Fuente, A.3
  • 8
    • 0001677717 scopus 로고
    • Controlling the false discovery rate: a practical and powerful approach to multiple testing
    • Benjamini B., Hochberg Y. Controlling the false discovery rate: a practical and powerful approach to multiple testing. J. R. Stat. Soc. B 1995, 57:289-300.
    • (1995) J. R. Stat. Soc. B , vol.57 , pp. 289-300
    • Benjamini, B.1    Hochberg, Y.2
  • 9
    • 22344449669 scopus 로고    scopus 로고
    • Constructing transcriptional regulatory networks
    • Blais A., Dynlacht B.D. Constructing transcriptional regulatory networks. Genes Dev. 2005, 19:1499-1511.
    • (2005) Genes Dev. , vol.19 , pp. 1499-1511
    • Blais, A.1    Dynlacht, B.D.2
  • 10
    • 33846283385 scopus 로고    scopus 로고
    • The evolution of gene regulation by transcription factors and microRNAs
    • Chen K., Rajewsky N. The evolution of gene regulation by transcription factors and microRNAs. Nat. Rev. Genet. 2007, 8:93-103.
    • (2007) Nat. Rev. Genet. , vol.8 , pp. 93-103
    • Chen, K.1    Rajewsky, N.2
  • 11
    • 8444226286 scopus 로고    scopus 로고
    • An alternative mode of action of endocrine-disrupting chemicals and chemoprevention
    • Choi S.M., Lee B.M. An alternative mode of action of endocrine-disrupting chemicals and chemoprevention. J. Toxicol. Environ. Health 2004, 7:451-463.
    • (2004) J. Toxicol. Environ. Health , vol.7 , pp. 451-463
    • Choi, S.M.1    Lee, B.M.2
  • 12
    • 0038274163 scopus 로고    scopus 로고
    • Links between tumor suppressors: p53 is required for tgf-beta gene responses by cooperating with Smads
    • Cordenonsi M., Dupont S., Maretto S., Insinga A., Imbriano C., Piccolo S. Links between tumor suppressors: p53 is required for tgf-beta gene responses by cooperating with Smads. Cell 2003, 113:301-314.
    • (2003) Cell , vol.113 , pp. 301-314
    • Cordenonsi, M.1    Dupont, S.2    Maretto, S.3    Insinga, A.4    Imbriano, C.5    Piccolo, S.6
  • 13
    • 33744947569 scopus 로고    scopus 로고
    • Endocrine regulation of HOX genes
    • Daftary G., Taylor H. Endocrine regulation of HOX genes. Endocr. Rev. 2006, 27:331-355.
    • (2006) Endocr. Rev. , vol.27 , pp. 331-355
    • Daftary, G.1    Taylor, H.2
  • 14
    • 2342488852 scopus 로고    scopus 로고
    • New insights into TGF-b-Smad signalling
    • Dijke P., Hill C.S. New insights into TGF-b-Smad signalling. Trends Biochem. Sci. 2004, 29:265-273.
    • (2004) Trends Biochem. Sci. , vol.29 , pp. 265-273
    • Dijke, P.1    Hill, C.S.2
  • 15
    • 59349084544 scopus 로고    scopus 로고
    • Intelligent testing strategies in ecotoxicology: mode of action approach for specifically acting chemicals
    • ECETOC, European Centre for Ecotoxicology and Toxicology of Chemicals, Brussels, Belgium
    • ECETOC Intelligent testing strategies in ecotoxicology: mode of action approach for specifically acting chemicals. ECETOC Technical Report No. 102 2007, European Centre for Ecotoxicology and Toxicology of Chemicals, Brussels, Belgium. http://www.ecetoc.org/technical-reports.
    • (2007) ECETOC Technical Report No. 102
  • 16
    • 56649086859 scopus 로고    scopus 로고
    • Systems biology and mode of action based risk assessment
    • Edwards S., Preston R. Systems biology and mode of action based risk assessment. Toxicol. Sci. 2008, 106:312-318.
    • (2008) Toxicol. Sci. , vol.106 , pp. 312-318
    • Edwards, S.1    Preston, R.2
  • 17
    • 23044466047 scopus 로고    scopus 로고
    • Specificity and versatility in tgf-β signaling through Smads
    • Feng X.-H., Derynck R. Specificity and versatility in tgf-β signaling through Smads. Annu. Rev. Cell Dev. Biol. 2005, 21:659-693.
    • (2005) Annu. Rev. Cell Dev. Biol. , vol.21 , pp. 659-693
    • Feng, X.-H.1    Derynck, R.2
  • 18
    • 0028139020 scopus 로고
    • Requiem: a novel zinc finger gene essential for apoptosis in myeloid cells
    • Gabig T.G., Mantel P.L., Rosli R., Crean C.D. Requiem: a novel zinc finger gene essential for apoptosis in myeloid cells. J. Biol. Chem. 1994, 269:29515-29519.
    • (1994) J. Biol. Chem. , vol.269 , pp. 29515-29519
    • Gabig, T.G.1    Mantel, P.L.2    Rosli, R.3    Crean, C.D.4
  • 19
    • 28044471827 scopus 로고    scopus 로고
    • Acetylation and deacetylation of non-histone proteins
    • Glozak M.A., Sengupta N., Zhang X.-H., Seto E. Acetylation and deacetylation of non-histone proteins. Gene 2005, 363:15-23.
    • (2005) Gene , vol.363 , pp. 15-23
    • Glozak, M.A.1    Sengupta, N.2    Zhang, X.-H.3    Seto, E.4
  • 20
    • 33644507479 scopus 로고    scopus 로고
    • Transcription factor YY1: structure, function, and therapeutic implications in cancer biology
    • Gordon S., Akopyan G., Garban H., Bonavida B. Transcription factor YY1: structure, function, and therapeutic implications in cancer biology. Oncogene 2006, 25:1125-1142.
    • (2006) Oncogene , vol.25 , pp. 1125-1142
    • Gordon, S.1    Akopyan, G.2    Garban, H.3    Bonavida, B.4
  • 21
    • 58149216052 scopus 로고    scopus 로고
    • Signaling cross-talk between TGF-β/BMP and other pathways
    • Guo X., Wang X.-F. Signaling cross-talk between TGF-β/BMP and other pathways. Cell Res. 2009, 19:71-88.
    • (2009) Cell Res. , vol.19 , pp. 71-88
    • Guo, X.1    Wang, X.-F.2
  • 22
  • 23
    • 62549108593 scopus 로고    scopus 로고
    • The evolution of Fox genes and their role in development and disease
    • Hannenhalli S., Kaestner K. The evolution of Fox genes and their role in development and disease. Nat. Rev. Genet. 2009, 10:233-240.
    • (2009) Nat. Rev. Genet. , vol.10 , pp. 233-240
    • Hannenhalli, S.1    Kaestner, K.2
  • 24
    • 77953683930 scopus 로고    scopus 로고
    • Epidemiologic evidence on the relationship between environmental endocrine disruptors and male reproductive and developmental health
    • Humana Press, New Jersey, A. Gore (Ed.)
    • Hauser R., Barthold J., Meeker J. Epidemiologic evidence on the relationship between environmental endocrine disruptors and male reproductive and developmental health. Endocrine Disrupting Chemicals 2007, 225-251. Humana Press, New Jersey. A. Gore (Ed.).
    • (2007) Endocrine Disrupting Chemicals , pp. 225-251
    • Hauser, R.1    Barthold, J.2    Meeker, J.3
  • 25
    • 0141996462 scopus 로고    scopus 로고
    • The role of the transcription factor DP in apoptosis
    • Hitchens M.R., Robbins P.D. The role of the transcription factor DP in apoptosis. Apoptosis 2003, 8:461-468.
    • (2003) Apoptosis , vol.8 , pp. 461-468
    • Hitchens, M.R.1    Robbins, P.D.2
  • 28
    • 0001368373 scopus 로고
    • Étude comparative de la distribution florale dans une portion des Alpes et des Jura
    • Jaccard P. Étude comparative de la distribution florale dans une portion des Alpes et des Jura. Bulletin del la Société Vaudoise des Sciences Naturelles 1901, 37:547-579.
    • (1901) Bulletin del la Société Vaudoise des Sciences Naturelles , vol.37 , pp. 547-579
    • Jaccard, P.1
  • 29
    • 77953684078 scopus 로고    scopus 로고
    • Endocrine disruption and reproductive outcomes in women
    • Humana Press, New Jersey, A. Gore (Ed.)
    • Janssen S., Fujimoto V., Giudice L. Endocrine disruption and reproductive outcomes in women. Endocrine Disrupting Chemicals 2007, 203-223. Humana Press, New Jersey. A. Gore (Ed.).
    • (2007) Endocrine Disrupting Chemicals , pp. 203-223
    • Janssen, S.1    Fujimoto, V.2    Giudice, L.3
  • 32
    • 67749113808 scopus 로고    scopus 로고
    • Transcriptional regulatory circuits: predicting numbers from alphabets
    • Kim H., Shay D., O'Shea T., Regev E.K.A. Transcriptional regulatory circuits: predicting numbers from alphabets. Science 2009, 325:429-432.
    • (2009) Science , vol.325 , pp. 429-432
    • Kim, H.1    Shay, D.2    O'Shea, T.3    Regev, E.K.A.4
  • 34
    • 33646807832 scopus 로고    scopus 로고
    • The P53 pathway: what questions remain to be explored?
    • Levine A.J., Hu W., Feng Z. The P53 pathway: what questions remain to be explored?. Cell Death Differ. 2006, 13:1027-1036.
    • (2006) Cell Death Differ. , vol.13 , pp. 1027-1036
    • Levine, A.J.1    Hu, W.2    Feng, Z.3
  • 35
    • 0037819447 scopus 로고    scopus 로고
    • Transcription regulation and animal diversity
    • Levine M., Tjian R. Transcription regulation and animal diversity. Nature 2003, 424:147-151.
    • (2003) Nature , vol.424 , pp. 147-151
    • Levine, M.1    Tjian, R.2
  • 36
    • 61949248719 scopus 로고    scopus 로고
    • Master regulators used as breast cancer metastasis classifier
    • Lim W.K., Eugenia L., Califano A. Master regulators used as breast cancer metastasis classifier. Pac. Symp. Biocomput. 2009, 14:504-515.
    • (2009) Pac. Symp. Biocomput. , vol.14 , pp. 504-515
    • Lim, W.K.1    Eugenia, L.2    Califano, A.3
  • 37
    • 34547666638 scopus 로고    scopus 로고
    • Endocrine-disrupting chemicals: a review of the state of the science
    • Manning T. Endocrine-disrupting chemicals: a review of the state of the science. Aust. J. Ecotoxicol. 2005, 11:1-52.
    • (2005) Aust. J. Ecotoxicol. , vol.11 , pp. 1-52
    • Manning, T.1
  • 39
    • 0032147094 scopus 로고    scopus 로고
    • Gene regulation by Y-box proteins:coupling control of transcription and translation
    • Matsumoto K., Wolffe A.P. Gene regulation by Y-box proteins:coupling control of transcription and translation. Trends Cell Biol. 1998, 8:318-323.
    • (1998) Trends Cell Biol. , vol.8 , pp. 318-323
    • Matsumoto, K.1    Wolffe, A.P.2
  • 43
    • 29544437442 scopus 로고    scopus 로고
    • Transcriptional regulation of early oogenesis: in search of masters
    • Pangas S.A., Rajkovic A. Transcriptional regulation of early oogenesis: in search of masters. Hum. Reprod. Update 2006, 12:65-76.
    • (2006) Hum. Reprod. Update , vol.12 , pp. 65-76
    • Pangas, S.A.1    Rajkovic, A.2
  • 44
    • 21444454257 scopus 로고    scopus 로고
    • False discovery rate, sensitivity and sample size for microarray studies
    • Pawitan Y., Michiels S., Koscielny S., Gusnanto A., Ploner A. False discovery rate, sensitivity and sample size for microarray studies. Bioinformatics 2005, 21:3017-3024.
    • (2005) Bioinformatics , vol.21 , pp. 3017-3024
    • Pawitan, Y.1    Michiels, S.2    Koscielny, S.3    Gusnanto, A.4    Ploner, A.5
  • 45
    • 0037223971 scopus 로고    scopus 로고
    • The evolution of signaling pathways in animal development
    • Pires-daSilva A., Sommer R. The evolution of signaling pathways in animal development. Nat. Rev. Genet. 2003, 4:39-49.
    • (2003) Nat. Rev. Genet. , vol.4 , pp. 39-49
    • Pires-daSilva, A.1    Sommer, R.2
  • 46
    • 38049147787 scopus 로고    scopus 로고
    • MEF2: a central regulator of diverse developmental programs
    • Potthoff M.J., Olson E.N. MEF2: a central regulator of diverse developmental programs. Development 2007, 134:4131-4140.
    • (2007) Development , vol.134 , pp. 4131-4140
    • Potthoff, M.J.1    Olson, E.N.2
  • 48
    • 1542285509 scopus 로고    scopus 로고
    • The GABA(B) receptor subunits R1 and R2 interact differentially with the activation transcription factor ATF4 in mouse brain during the postnatal development
    • Ritter B., Zschuntsch J., Kvachnina E., Zhang W., Ponimaskin E.G. The GABA(B) receptor subunits R1 and R2 interact differentially with the activation transcription factor ATF4 in mouse brain during the postnatal development. Brain Res. Dev. Brain Res. 2004, 149:73-77.
    • (2004) Brain Res. Dev. Brain Res. , vol.149 , pp. 73-77
    • Ritter, B.1    Zschuntsch, J.2    Kvachnina, E.3    Zhang, W.4    Ponimaskin, E.G.5
  • 49
    • 33144481710 scopus 로고    scopus 로고
    • The Mad side of the Max network: antagonizing the function of Myc and more
    • Rottmann S., Lüscher B. The Mad side of the Max network: antagonizing the function of Myc and more. Curr. Top. Microbiol. Immunol. 2006, 302:63-122.
    • (2006) Curr. Top. Microbiol. Immunol. , vol.302 , pp. 63-122
    • Rottmann, S.1    Lüscher, B.2
  • 50
    • 27544479100 scopus 로고    scopus 로고
    • B-MYB, a transcription factor implicated in regulating cell cycle, apoptosis and cancer
    • Sala A. B-MYB, a transcription factor implicated in regulating cell cycle, apoptosis and cancer. Eur. J. Cancer 2005, 41:2479-2484.
    • (2005) Eur. J. Cancer , vol.41 , pp. 2479-2484
    • Sala, A.1
  • 51
    • 33749585599 scopus 로고    scopus 로고
    • The steroid hormone biosynthesis pathway as a target for endocrine-disrupting chemicals
    • Sanderson J. The steroid hormone biosynthesis pathway as a target for endocrine-disrupting chemicals. Toxicol. Sci. 2006, 94:3-21.
    • (2006) Toxicol. Sci. , vol.94 , pp. 3-21
    • Sanderson, J.1
  • 53
    • 0242468041 scopus 로고    scopus 로고
    • Regulation of Jak-Stat signalling in the immune system
    • Shuai K., Liu B. Regulation of Jak-Stat signalling in the immune system. Nat. Rev. Immunol. 2003, 3:900-911.
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 900-911
    • Shuai, K.1    Liu, B.2
  • 56
    • 33344456597 scopus 로고    scopus 로고
    • New modes of action for endocrine-disrupting chemicals
    • Tabb M., Blumberg B. New modes of action for endocrine-disrupting chemicals. Mol. Endocrinol. 2006, 20:475-482.
    • (2006) Mol. Endocrinol. , vol.20 , pp. 475-482
    • Tabb, M.1    Blumberg, B.2
  • 57
    • 60849115568 scopus 로고    scopus 로고
    • Human Nei-like protein NEIL3 has AP lyase activity specific for single-stranded DNA and confers oxidative stress resistance in Escherichia coli mutant
    • Takao M., Oohata Y., Kitadokoro K., Kobayashi K., Iwai S., Yasui A., Yonei S., Zhang Q.M. Human Nei-like protein NEIL3 has AP lyase activity specific for single-stranded DNA and confers oxidative stress resistance in Escherichia coli mutant. Genes Cells 2009, 14:261-270.
    • (2009) Genes Cells , vol.14 , pp. 261-270
    • Takao, M.1    Oohata, Y.2    Kitadokoro, K.3    Kobayashi, K.4    Iwai, S.5    Yasui, A.6    Yonei, S.7    Zhang, Q.M.8
  • 58
    • 34547781750 scopus 로고    scopus 로고
    • MEGA4: molecular evolutionary genetics analysis (MEGA) software version 4.0
    • Tamura K., Dudley J., Nei M., Kumar S. MEGA4: molecular evolutionary genetics analysis (MEGA) software version 4.0. Mol. Biol. Evol. 2007, 24:1596-1599.
    • (2007) Mol. Biol. Evol. , vol.24 , pp. 1596-1599
    • Tamura, K.1    Dudley, J.2    Nei, M.3    Kumar, S.4
  • 60
    • 0033602101 scopus 로고    scopus 로고
    • Inhibition of transforming growth factor-β/SMAD signalling by the interferon-γ/STAT pathway
    • Ulloa L., Doody J., Massaguae J. Inhibition of transforming growth factor-β/SMAD signalling by the interferon-γ/STAT pathway. Nature 1999, 397:710-713.
    • (1999) Nature , vol.397 , pp. 710-713
    • Ulloa, L.1    Doody, J.2    Massaguae, J.3
  • 61
    • 0003747975 scopus 로고    scopus 로고
    • US Environmental Protection Agency, Office of Prevention, Pesticides and Toxic Substances, US Environmental Protection Agency, Washington, DC
    • US Environmental Protection Agency Endocrine Disruptor Screening and Testing Advisory Committee (EDSTAC) Final Report 1998, Office of Prevention, Pesticides and Toxic Substances, US Environmental Protection Agency, Washington, DC. http://www.epa.gov/scipoly/oscpendo/pubs/edspoverview/finalrpt.htm.
    • (1998) Endocrine Disruptor Screening and Testing Advisory Committee (EDSTAC) Final Report
  • 62
    • 62549128139 scopus 로고    scopus 로고
    • A census of human transcription factors: function, expression and evolution
    • Vaquerizas J., Kummerfeld S., Teichmann S., Luscombe N. A census of human transcription factors: function, expression and evolution. Nat. Rev. Genet. 2009, 10:252-263.
    • (2009) Nat. Rev. Genet. , vol.10 , pp. 252-263
    • Vaquerizas, J.1    Kummerfeld, S.2    Teichmann, S.3    Luscombe, N.4
  • 64
    • 69049113953 scopus 로고    scopus 로고
    • Altered gene expression in the brain and ovaries of zebrafish exposed to the aromatase inhibitor fadrozole: microarray analysis and hypothesis generation
    • Villeneuve D.L., Wang R.-L., Bencic D.C., Biales A.D., Martinovic D., Lazorchak J.M., Toth G., Ankley G.T. Altered gene expression in the brain and ovaries of zebrafish exposed to the aromatase inhibitor fadrozole: microarray analysis and hypothesis generation. Environ. Toxicol. Chem. 2009, 28:1767-1782.
    • (2009) Environ. Toxicol. Chem. , vol.28 , pp. 1767-1782
    • Villeneuve, D.L.1    Wang, R.-L.2    Bencic, D.C.3    Biales, A.D.4    Martinovic, D.5    Lazorchak, J.M.6    Toth, G.7    Ankley, G.T.8
  • 65
    • 40949111044 scopus 로고    scopus 로고
    • DNA microarray application in ecotoxicology: experimental design, microarray scanning, and factors affecting transcriptional profiles in a small fish species
    • Wang R.-L., Biales A.D., Bencic D.C., Lattier D., Kostich M., Villeneuve D.L., Ankley G.T., Lazorchak J.M., Toth G. DNA microarray application in ecotoxicology: experimental design, microarray scanning, and factors affecting transcriptional profiles in a small fish species. Environ. Toxicol. Chem. 2008, 27:652-663.
    • (2008) Environ. Toxicol. Chem. , vol.27 , pp. 652-663
    • Wang, R.-L.1    Biales, A.D.2    Bencic, D.C.3    Lattier, D.4    Kostich, M.5    Villeneuve, D.L.6    Ankley, G.T.7    Lazorchak, J.M.8    Toth, G.9
  • 67
    • 33749825955 scopus 로고    scopus 로고
    • Comparative evaluation of reverse engineering gene regulatory networks with relevance networks, graphical Gaussian models and Bayesian networks
    • Werhli A.V., Grzegorczyk M., Husmeier D. Comparative evaluation of reverse engineering gene regulatory networks with relevance networks, graphical Gaussian models and Bayesian networks. Bioinformatics 2006, 22:2523-2531.
    • (2006) Bioinformatics , vol.22 , pp. 2523-2531
    • Werhli, A.V.1    Grzegorczyk, M.2    Husmeier, D.3
  • 68
    • 38549146907 scopus 로고    scopus 로고
    • DBD-taxonomically broad transcription factor predictions: new content and functionality
    • Wilson D., Charoensawan V., Kummerfeld S.K., Teichmann S.A. DBD-taxonomically broad transcription factor predictions: new content and functionality. Nucleic Acids Res. 2008, 36:D88-92.
    • (2008) Nucleic Acids Res. , vol.36
    • Wilson, D.1    Charoensawan, V.2    Kummerfeld, S.K.3    Teichmann, S.A.4
  • 69
    • 0004094150 scopus 로고    scopus 로고
    • Global assessment of the state-of-the-science of endocrine disruptors
    • World Health Organization (WHO), WHO/PCS/EDC/02.2, T. Damstra, S. Barlow, A. Bergman, R. Kavlock, G. Van Der Kraak (Eds.)
    • World Health Organization (WHO) Global assessment of the state-of-the-science of endocrine disruptors. International Programme on Chemical Safety 2002, WHO/PCS/EDC/02.2. T. Damstra, S. Barlow, A. Bergman, R. Kavlock, G. Van Der Kraak (Eds.).
    • (2002) International Programme on Chemical Safety
  • 70
    • 0033515620 scopus 로고    scopus 로고
    • A Smad transcriptional corepressor
    • Wotton D., Lo R.S., Lee S., Massague J. A Smad transcriptional corepressor. Cell 1999, 97:29-39.
    • (1999) Cell , vol.97 , pp. 29-39
    • Wotton, D.1    Lo, R.S.2    Lee, S.3    Massague, J.4
  • 71
    • 40449087178 scopus 로고    scopus 로고
    • YB-1 is a transcription/translation factor that orchestrates the oncogenome by hardwiring signal transduction to gene expression
    • Wu J., Stratford A.L., Astanehe A., Dunn S.E. YB-1 is a transcription/translation factor that orchestrates the oncogenome by hardwiring signal transduction to gene expression. Translat. Oncogenomics 2007, 2:49-65.
    • (2007) Translat. Oncogenomics , vol.2 , pp. 49-65
    • Wu, J.1    Stratford, A.L.2    Astanehe, A.3    Dunn, S.E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.