Cellular cardiomyoplasty and cardiac tissue engineering for myocardial therapy

Advanced Drug Delivery Reviews

Volumn 62, Issue 7-8, 2010, Pages 784-797

  Wang, Feng ^a   Guan Jianjun, J ^a  

^a Ohio State University   (United States)

Author keywords

Biomaterials; Cell therapy; Congestive heart failure; Growth factor delivery; Myocardial infarction; Tissue engineering

Indexed keywords

CARDIAC FUNCTIONS; CARDIAC MUSCLES; CARDIAC REPAIR; CARDIAC TISSUE ENGINEERING; CARDIOMYOCYTES; CELL DIFFERENTIATION; CELL RETENTION; CELL SHEET; CELL THERAPY; CELL TYPES; CELLULAR THERAPY; CONGESTIVE HEART FAILURES; GROWTH FACTOR; GROWTH FACTOR DELIVERY; HEART DISEASE; HOST TISSUES; IN-SITU; IN-VITRO; IN-VIVO; INJECTABLE BIOMATERIALS; MORTALITY RATE; MYOCARDIAL INFARCTION; STEM CELL; TISSUE CONSTRUCTS; TRANSPLANTED CELLS;

BIOACTIVITY; CYTOLOGY; ENGINEERING; HEART; PEPTIDES; POPULATION STATISTICS; REPAIR; SAFETY ENGINEERING; STEM CELLS; TABLE LOOKUP; TISSUE;

TISSUE ENGINEERING;

ALGINIC ACID; BIOMATERIAL; CHITOSAN; COLLAGEN; FIBRIN; GELATIN; GLYCOSAMINOGLYCAN; KRUPPEL LIKE FACTOR 4; MATRIGEL; MYC PROTEIN; OCTAMER TRANSCRIPTION FACTOR 4; POLY(GLYCEROL SEBACATE); POLY(N ISOPROPYLACRYLAMIDE); POLYCAPROLACTONE; POLYGLACTIN; POLYLACTIDE; POLYMER; POLYURETHAN; TISSUE SCAFFOLD; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR SOX2; UNCLASSIFIED DRUG;

ADIPOSE TISSUE; ANGIOGENESIS; CARDIOMYOPLASTY; CELL DEATH; CELL DIFFERENTIATION; CELL SURVIVAL; CELL THERAPY; CELL TRANSFER; CELL TRANSPLANTATION; CELL TYPE; CONGESTIVE HEART FAILURE; EMBRYONIC STEM CELL; ENGRAFTMENT; HEART FUNCTION; HEART INFARCTION; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILITY; HEART MUSCLE INJURY; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMAN; IN VITRO STUDY; IN VIVO STUDY; MESENCHYMAL STEM CELL TRANSPLANTATION; MORTALITY; MUSCLE DEVELOPMENT; MUSCLE REGENERATION; MYOBLAST; PARACRINE SIGNALING; PRIORITY JOURNAL; REVIEW; TISSUE ENGINEERING; TISSUE REPAIR;

ANIMALS; CARDIOMYOPLASTY; CELL TRANSPLANTATION; HEART FAILURE; HUMANS; MYOCARDIAL INFARCTION; MYOCARDIUM; MYOCYTES, CARDIAC; REGENERATION; STEM CELL TRANSPLANTATION; TISSUE ENGINEERING;

EID: 77953683474     PISSN: 0169409X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.addr.2010.03.001     Document Type: Review

References (194)

1. Rosamond W., Flegal K., Friday G., Furie K., Go A., Greenlund K., et al. Heart disease and stroke statistics-2007 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation 2007, 115:e69-e171.
2. Taylor D.A., Zenovich A.G. Cardiovascular cell therapy and endogenous repair. Diab. Obes. Metab. 2008, 10:5-15.
3. Taylor D.A. Cell-based myocardial repair: how should we proceed?. Int. J. Cardiol. 2004, 95:S8-S12.
4. Lloyd-Jones D.M. The risk of congestive heart failure: sobering lessons from the Framingham heart study. Curr. Cardiol. Rep. 2001, 3:184-190.
5. Li S.C., Wang L., Jiang H., Acevedo J., Chang A.C., Loudon W.G. Stem cell engineering for treatment of heart diseases: potentials and challenges. Cell Biol. Int. 2009, 33:255-267.
6. Beltrami A.P., Barlucchi L., Torella D., Baker M., Limana F., Chimenti S., et al. Adult cardiac stem cells are multipotent and support myocardial regeneration. Cell 2003, 114:763-776.
7. Germani A., Limana F., Capogrossi M.C. Pivotal advances: High-mobility group box 1 protein-a cytokine with a role in cardiac repair. J. Leukoc. Biol. 2007, 81:41-45.
8. Zenovich A.G., Taylor D.A. Atherosclerosis as a disease of failed endogenous repair. Front. Biosci. 2008, 13:3621-3636.
9. McMullen N.M., Pasumarthi K.B. Donor cell transplantation for myocardial disease: does it complement current pharmacological therapies?. Can. J. Physiol. Pharmacol. 2007, 85:1-15.
10. Soonpaa M., Koh G., Klug M., Field L. Formation of nascent intercalated disks between grafted fetal cardiomyocytes and host myocardium. Science 1994, 264:98-101.
11. Rubart M., Pasumarthi K.B., Nakajima H., Soonpaa M.H., Nakajima H.O., Field L.J. Physiological coupling of donor and host cardiomyocytes after cellular transplantation. Circ. Res. 2003, 92:1217-1224.
12. Reinecke H., Zhang M., Bartosek T., Murry C.E. Survival, integration, and differentiation of cardiomyocyte grafts: a study in normal and injured rat hearts. Circulation 1999, 100:193-202.
13. Li R., Weisel R.D., Mickle D.A.G., Jia Z., Kim E., Sakai T., et al. Autologous porcine heart cell transplantation improved heart function after a myocardial infarction. J. Thorac. Cardiovasc. Surg. 2000, 119:62-68.
14. Sherman W. Myocyte replacement therapy: skeletal myoblasts. Cell Transplant. 2007, 16:971-975.
15. Reinlib L., Field L. Cell transplantation as future therapy for cardiovascular disease?: A workshop of the National Heart, Lung, and Blood Institute. Circulation 2000, 101:e182-e187.
16. Hagege A.A., Marolleau J., Vilquin J., Alheritiere A., Peyrard S., Duboc D., et al. Skeletal myoblast rransplantation in ischemic heart failure: long-term follow-up of the first phase I cohort of patients. Circulation 2006, 114(I):108-113.
17. Al Attar N., Carrion C., Ghostine S., Garcin I., Vilquin J., Hagège A.A., et al. Long-term (1year) functional and histological results of autologous skeletal muscle cells transplantation in rat. Cardiovasc. Res. 2003, 58:142-148.
18. Murry C., Wiseman R., Schwartz S., Hauschka S. Skeletal myoblast transplantation for repair of myocardial necrosis. J. Clin. Invest. 1996, 98:2512-2523.
19. Leobon B. Myoblasts transplanted into rat infarcted myocardium are functionally isolated from their host. Proc. Natl. Acad. Sci. U. S. A 2003, 100:7808-7811.
20. Weissman I.L. Stem cells: units of development, units of regeneration, and units in evolution. Cell 2000, 100:157-168.
21. Le Blanc K., Pittenger M. Mesenchymal stem cells: progress toward promise. Cytotherapy 2005, 7:36-45.
22. Heng B.C., Haider H.K., Sim E.K., Cao T., Ng S.C. Strategies for directing the differentiation of stem cells into the cardiomyogenic lineage in vitro. Cardiovasc. Res. 2004, 62:34-42.
23. Reyes M., Lund T., Lenvik T., Aguiar D., Koodie L., Verfaillie C.M. Purification and ex vivo expansion of postnatal human marrow mesodermal progenitor cells. Blood 2001, 98:2615-2625.
24. Shi Q., Rafii S., Wu M.H., Wijelath E.S., Yu C., Ishida A., et al. Evidence for circulating bone marrow-derived endothelial cells. Blood 1998, 92:362-367.
25. Bittner R.E., Schö C., Weipoltshammer K., Ivanova S., Streubel B., et al. Recruitment of bone-marrow-derived cells by skeletal and cardiac muscle in adult dystrophic mdx mice. Anat. Embryol. 1999, 199:391-396.
26. Orlic D., Kajstura J., Chimenti S., Jakoniuk I., Anderson S.M., Li B., et al. Bone marrow cells regenerate infarcted myocardium. Nature 2001, 410:701-705.
27. Assmus B., Schächinger V., Teupe C., Britten M., Lehmann R., Döbert N., et al. Transplantation of progenitor cells and regeneration enhancement in acute myocardial infarction. Circulation 2002, 106:3009-3017.
28. Losordo D.W., Dimmeler S. Therapeutic angiogenesis and vasculogenesis for ischemic disease: part II: cell-based therapies. Circulation 2004, 109:2692-2697.
29. Hill J.M., Zalos G., Halcox J.P.J., Schenke W.H., Waclawiw M.A., Quyyumi A.A., et al. Circulating endothelial progenitor cells, vascular function, and cardiovascular risk. N. Engl. J. Med. 2003, 348:593-600.
30. Vasa M., Fichtlscherer S., Aicher A., Adler K., Urbich C., Martin H., et al. Number and migratory activity of circulating endothelial progenitor cells inversely correlate with risk factors for coronary artery disease. Circ. Res. 2001, 89:E1-E7.
31. Makino S., Fukuda K., Miyoshi S., Konishi F., Kodama H., Pan J., et al. Cardiomyocytes can be generated from marrow stromal cells in vitro. J. Clin. Invest. 1999, 103:697-705.
32. Toma C., Pittenger M.F., Cahill K.S., Byrne B.J., Kessler P.D. Human mesenchymal stem cells differentiate to a cardiomyocyte phenotype in the adult murine heart. Circulation 2002, 105:93-98.
33. Mangi A.A., Noiseux N., Kong D., He H., Rezvani M., Ingwall J.S., et al. Mesenchymal stem cells modified with Akt prevent remodeling and restore performance of infarcted hearts. Nat. Med. 2003, 9:1195-1201.
34. Wang J.S., Shum-Tim D., Chedrawy E., Eliopoulos N., Galipeau J., Chiu R.C.J. Marrow stromal cells for cellular cardiomyoplasty: the importance of microenvironment for milieu dependent differentiation. Circulation 2000, 102:3300.
35. Gojo S., Gojo N., Takeda Y., Mori T., Abe H., Kyo S., et al. In vivo cardiovasculogenesis by direct injection of isolated adult mesenchymal stem cells. Exp. Cell Res. 2003, 288:51-59.
36. Shake J.G., Gruber P.J., Baumgartner W.A., Senechal G., Meyers J., Redmond J.M., et al. Mesenchymal stem cell implantation in a swine myocardial infarct model: engraftment and functional effects. Ann. Thorac. Surg. 2002, 73:1919-1925.
37. Tomita S., Li R.K., Weisel R.D., Mickle D.A., Kim E.J., Sakai T., et al. Autologous transplantation of bone marrow cells improves damaged heart function. Circulation 1999, 100:II247-II256.
38. Tomita S., Mickle D.A.G., Weisel R.D., Jia Z., Tumiati L.C., Allidina Y., et al. Improved heart function with myogenesis and angiogenesis after autologous porcine bone marrow stromal cell transplantation. J. Thorac. Cardiovasc. Surg. 2002, 123:1132-1140.
39. Davani S., Marandin A., Mersin N., Royer B., Kantelip B., Hervé P., et al. Mesenchymal progenitor cells differentiate into an endothelial phenotype, enhance vascular density, and improve heart function in a rat cellular cardiomyoplasty model. Circulation 2003, 108:II253-II258.
40. Murry C.E., Field L.J., Menasche P. Cell-based cardiac repair: reflections at the 10-year point. Circulation 2005, 112:3174-3183.
41. Balsam L., Robbins R. Haematopoietic stem cells and repair of the ischaemic heart. Clin. Sci. 2005, 109:483.
42. Abkowitz J.L., Catlin S.N., McCallie M.T., Guttorp P. Evidence that the number of hematopoietic stem cells per animal is conserved in mammals. Blood 2002, 100:2665-2667.
43. Pittenger M.F., Martin B.J. Mesenchymal stem cells and their potential as cardiac therapeutics. Circ. Res. 2004, 95:9-20.
44. Laflamme M.A., Murry C.E. Regenerating the heart. Nat. Biotechnol. 2005, 23:845-856.
45. Doetschman T.C., Eistetter H., Katz M., Schmidt W., Kemler R. The in vitro development of blastocyst-derived embryonic stem cell lines: formation of visceral yolk sac, blood islands and myocardium. J. Embryol. Exp. Morphol. 1985, 87:27-45.
46. Kehat I., Kenyagin-Karsenti D., Snir M., Segev H., Amit M., Gepstein A., et al. Human embryonic stem cells can differentiate into myocytes with structural and functional properties of cardiomyocytes. J. Clin. Invest. 2001, 108:407-414.
47. Zandstra P., Bauwens C., Yin T., Liu Q., Schiller H., Zweigerdt R., et al. Scalable production of embryonic stem cell-derived cardiomyocytes. Tissue Eng. 2003, 9:767-778.
48. Zhang F., Pasumarthi K.B.S. Embryonic stem cell transplantation: promise and progress in the treatment of heart disease. BioDrugs 2008, 22:361-374.
49. Klug M.G., Soonpaa M.H., Koh G.Y., Field L.J. Genetically selected cardiomyocytes from differentiating embryonic stem cells form stable intracardiac grafts. J. Clin. Invest. 1996, 98:216-224.
50. Reinecke H., Murry C.E. Taking the death toll after cardiomyocyte grafting: a reminder of the importance of quantitative biology. J. Mol. Cell Cardiol. 2002, 34:251-253.
51. Laflamme M.A., Chen K.Y., Naumova A.V., Muskheli V., Fugate J.A., Dupras S.K., et al. Cardiomyocytes derived from human embryonic stem cells in pro-survival factors enhance function of infarcted rat hearts. Nat. Biotechnol. 2007, 25:1015-1024.
52. Nussbaum J., Minami E., Laflamme M.A., Virag J.A.I., Ware C.B., Masino A., et al. Transplantation of undifferentiated murine embryonic stem cells in the heart: teratoma formation and immune response. FASEB J. 2007, 21:1345-1357.
53. Das S., Bonaguidi M., Muro K., Kessler J.A. Generation of embryonic stem cells: limitations of and alternatives to inner cell mass harvest. Neurosurg. Focus 2008, 24:E4.
54. Pralong D., Mrozik K., Occhiodoro F., Wijesundara N., Sumer H., Van Boxtel A.L., et al. A novel method for somatic cell nuclear transfer to mouse embryonic. Stem Cells 2005, 7:265-271.
55. Tamada H., Kikyo N. Nuclear reprogramming in mammalian somatic cell nuclear cloning. Cytogenet. Genome Res. 2004, 105:285-291.
56. Chung Y., Klimanskaya I., Becker S., Marh J., Lu S., Johnson J., et al. Embryonic and extraembryonic stem cell lines derived from single mouse blastomeres. Nature 2006, 439:216-219.
57. Klimanskaya I., Chung Y., Becker S., Lu S., Lanza R. Human embryonic stem cell lines derived from single blastomeres. Nature 2006, 444:481-485.
58. Park I., Zhao R., West J.A., Yabuuchi A., Huo H., Ince T.A., et al. Reprogramming of human somatic cells to pluripotency with defined factors. Nature 2008, 451:141-146.
59. Yu J., Vodyanik M.A., Smuga-Otto K., Antosiewicz-Bourget J., Frane J.L., Tian S., et al. Induced pluripotent stem cell lines derived from human somatic cells. Science 2007, 318:1917-1920.
60. Planat-Benard V., Silvestre J., Cousin B., André M., Nibbelink M., Tamarat R., et al. Plasticity of human adipose lineage cells toward endothelial cells: physiological and therapeutic perspectives. Circulation 2004, 109:656-663.
61. Rangappa S., Fen C., Lee E.H., Bongso A., Sim E.K.W., Wei E.K.S. Transformation of adult mesenchymal stem cells isolated from the fatty tissue into cardiomyocytes. Ann. Thorac. Surg. 2003, 75:775-779.
62. Beltrami A.P., Urbanek K., Kajstura J., Yan S.M., Finato N., Bussani R., et al. Evidence that human cardiac myocytes divide after myocardial infarction. N. Engl. J. Med. 2001, 344:1750-1757.
63. Nadal-Ginard B., Kajstura J., Leri A., Anversa P. Myocyte death, growth, and regeneration in cardiac hypertrophy and failure. Circ. Res. 2003, 92:139-150.
64. Quaini F., Urbanek K., Beltrami A.P., Finato N., Beltrami C.A., Nadal-Ginard B., et al. Chimerism of the transplanted heart. N. Engl. J. Med. 2002, 346:5-15.
65. Kajstura J., Leri A., Finato N., Di Loreto C., Beltrami C.A., Anversa P. Myocyte proliferation in end-stage cardiac failure in humans. Proc. Natl Acad. Sci. U. S. A 1998, 95:8801-8805.
66. Torella D., Ellison G.M., Méndez-Ferrer S., Ibanez B., Nadal-Ginard B. Resident human cardiac stem cells: role in cardiac cellular homeostasis and potential for myocardial regeneration. Nat. Clin. Pract. Cardiovasc. Med. 2006, 3(Suppl 1):S8-S13.
67. Urbanek K., Quaini F., Tasca G., Torella D., Castaldo C., Nadal-Ginard B., et al. Intense myocyte formation from cardiac stem cells in human cardiac hypertrophy. Proc. Natl Acad. Sci. U. S. A 2003, 100:10440-10445.
68. Matsuura K., Nagai T., Nishigaki N., Oyama T., Nishi J., Wada H., et al. Adult cardiac Sca-1-positive cells differentiate into beating cardiomyocytes. J. Biol. Chem. 2004, 279:11384-11391.
69. Barile L., Messina E., Giacomello A., Marbán E. Endogenous cardiac stem cells. Prog. Cardiovasc. Dis. 2007, 50:31-48.
70. Takahashi K., Tanabe K., Ohnuki M., Narita M., Ichisaka T., Tomoda K., et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 2007, 131:861-872.
71. Yu J., Vodyanik M.A., Smuga-Otto K., Antosiewicz-Bourget J., Frane J.L., Tian S., et al. Induced pluripotent stem cell lines derived from human somatic cells. Science 2007, 318:1917-1920.
72. Zwi L., Caspi O., Arbel G., Huber I., Gepstein A., Park I., et al. Cardiomyocyte differentiation of human induced pluripotent stem cells. Circulation 2009, 120:1513-1523.
73. Nelson T.J., Martinez-Fernandez A., Yamada S., Perez-Terzic C., Ikeda Y., Terzic A. Repair of acute myocardial infarction by human stemness factors induced pluripotent stem cells. Circulation 2009, 120:408-416.
74. Wang Y., Yuan F. Delivery of viral vectors to tumor cells: extracellular transport, systemic distribution, and strategies for improvement. Ann. Biomed. Eng. 2007, 34:114-127.
75. Min J., Yang Y., Converso K.L., Liu L., Huang Q., Morgan J.P., et al. Transplantation of embryonic stem cells improves cardiac function in postinfarcted rats. J. Appl. Physiol. 2002, 92:288-296.
76. Kocher A., Schuster M., Szabolcs M., Takuma S., Burkhoff D., Wang J., et al. Neovascularization of ischemic myocardium by human bone-marrow-derived angioblasts prevents cardiomyocyte apoptosis, reduces remodeling and improves cardiac function. Nat. Med. 2001, 7:430-436.
77. Britten M., Abolmaali N., Assmus B., Lehmann R., Honold J., Schmitt J., et al. Infarct remodeling after intracoronary progenitor cell treatment in patients with acute myocardial infarction (TOPCARE-AMI): mechanistic insights from serial contrast-enhanced magnetic resonance imaging. Circulation 2003, 108:2212-2218.
78. Makino S., Fukuda K., Miyoshi S., Konishi F., Kodama H., Pan J., et al. Cardiomyocytes can be generated from marrow stromal cells in vitro. J. Clin. Invest. 1999, 103:697-705.
79. Deb A., Wang S., Skelding K.A., Miller D., Simper D., Caplice N.M. Bone marrow-derived cardiomyocytes are present in adult human heart: a study of gender-mismatched bone marrow transplantation patients. Circulation 2003, 107:1247-1249.
80. Höcht-Zeisberg E., Kahnert H., Guan K., Wulf G., Hemmerlein B., Schlott T., et al. Cellular repopulation of myocardial infarction in patients with sex-mismatched heart transplantation. Eur. Heart J. 2004, 25:749-758.
81. Nygren J.M., Jovinge S., Breitbach M., Säwén P., Röll W., Hescheler J., et al. Bone marrow-derived hematopoietic cells generate cardiomyocytes at a low frequency through cell fusion, but not transdifferentiation. Nat. Med. 2004, 10:494-501.
82. Ferreira L.S., Gerecht S., Shieh H.F., Watson N., Rupnick M.A., Dallabrida S.M., et al. Vascular progenitor cells isolated from human embryonic stem cells give rise to endothelial and smooth muscle like cells and form vascular networks in vivo. Circ. Res. 2007, 101:286-294.
83. Yamamoto K., Sokabe T., Watabe T., Miyazono K., Yamashita J.K., Obi S., et al. Fluid shear stress induces differentiation of Flk-1-positive embryonic stem cells into vascular endothelial cells in vitro. Am. J. Physiol. Heart Circ. Physiol. 2005, 288:H1915-H1924.
84. Ishikawa M., Asahara T. Endothelial progenitor cell culture for vascular regeneration. Stem Cells Dev. 2004, 13:344-349.
85. Orlic D., Kajstura J., Chimenti S., Limana F., Jakoniuk I., Quaini F., et al. Mobilized bone marrow cells repair the infarcted heart, improving function and survival. Proc. Natl Acad. Sci. U. S. A 2001, 98:10344-10349.
86. Dohmann H.F., Perin E.C., Takiya C.M., Silva G.V., Silva S.A., Sousa A.L., et al. Transendocardial autologous bone marrow mononuclear cell injection in ischemic heart failure: postmortem anatomicopathologic and immunohistochemical findings. Circulation 2005, 112:521-526.
87. Lenk K., Adams V., Erbs S., Linke A., Gielen S., Schmidt A., et al. Therapeutical potential of blood-derived progenitor cells in patients with peripheral arterial occlusive disease and critical limb ischaemia. Eur. Heart J. 2005, 26:1903-1909.
88. Urbich C., Aicher A., Heeschen C., Dernbach E., Hofmann W.K., Zeiher A.M., et al. Soluble factors released by endothelial progenitor cells promote migration of endothelial cells and cardiac resident progenitor cells. J. Mol. Cell Cardiol. 2005, 39:733-742.
89. Takahashi M., Li T., Suzuki R., Kobayashi T., Ito H., Ikeda Y., et al. Cytokines produced by bone marrow cells can contribute to functional improvement of the infarcted heart by protecting cardiomyocytes from ischemic injury. Am. J. Physiol. Heart Circ. Physiol. 2006, 291:H886-H893.
90. Herrmann J.L., Wang Y., Abarbanell A.M., Weil B.R., Tan J., Meldrum D.R. Preconditioning mesenchymal stem cells with transforming growth factor-? improves mesenchymal stem cell-mediated cardioprotection. Shock 2006, 33:24-30.
91. Kim H., Haider H., Jiang S., Ashraf M. Ischemic preconditioning augments survival of stem cells via mir-210 expression by targeting caspase-8-associated protein 2. J. Biol. Chem. 2009, 284:33161-33168.
92. Christman K.L., Lee R.J. Biomaterials for the treatment of myocardial infarction. J. Am. Coll. Cardiol. 2006, 48:907-913.
93. Reffelmann T., Kloner R.A. Cellular cardiomyoplasty - cardiomyocytes, skeletal myoblasts, or stem cells for regenerating myocardium and treatment of heart failure?. Cardiovasc. Res. 2003, 58:358-368.
94. Hofmann M., Wollert K.C., Meyer G.P., Menke A., Arseniev L., Hertenstein B., et al. Monitoring of bone marrow cell homing into the infarcted human myocardium. Circulation 2005, 111:2198-2202.
95. Hou D., Youssef E.A., Brinton T.J., Zhang P., Rogers P., Price E.T., et al. Radiolabeled cell distribution after intramyocardial, intracoronary, and interstitial retrograde coronary venous delivery: implications for current clinical trials. Circulation 2005, 112:I150-I156.
96. Sakakibara Y., Nishimura K., Tambara K., Yamamoto M., Lu F., Tabata Y., et al. Prevascularization with gelatin microspheres containing basic fibroblast growth factor enhances the benefits of cardiomyocyte transplantation. J. Thorac. Cardiovasc. Surg. 2002, 124:50-56.
97. Zhang G., Hu Q., Braunlin E.A., Suggs L.J., Zhang J. Enhancing efficacy of stem cell transplantation to the heart with a PEGylated fibrin biomatrix. Tissue Eng. Part A 2008, 14:1025-1036.
98. Forrester J.S., Makkar R.R., Marbán E. Long-term outcome of stem cell therapy for acute myocardial infarction: right results, wrong reasons. J. Am. Coll. Cardiol. 2009, 53:2270-2272.
99. Iwakura A., Fujita M., Kataoka K. Intramyocardial sustained delivery of basic fibroblast growth factor improves angiogenesis and ventricular function in a rat infarct model. Heart Vessels 2003, 18:93-99.
100. Christman K.L., Fang Q., Yee M.S., Johnson K.R., Sievers R.E., Lee R.J. Enhanced neovasculature formation in ischemic myocardium following delivery of pleiotrophin plasmid in a biopolymer. Biomaterials 2005, 26:1139-1144.
101. Hsieh P.C., Davis M.E., Gannon J., MacGillivray C., Lee R.T. Controlled delivery of PDGF-BB for myocardial protection using injectable self-assembling peptide nanofibers. J. Clin. Invest. 2006, 116:237-248.
102. Christman K.L., Vardanian A.J., Fang Q., Sievers R.E., Fok H.H., Lee R.J. Injectable fibrin scaffold improves cell transplant survival, reduces infarct expansion, and induces neovasculature formation in ischemic myocardium. J. Am. Coll. Cardiol. 2004, 44:654-660.
103. Yu J., Christman K.L., Chin E., Sievers R.E., Saeed M., Lee R.J. Restoration of left ventricular geometry and improvement of left ventricular function in a rodent model of chronic ischemic cardiomyopathy. J. Thorac. Cardiovasc. Surg. 2009, 137:180-187.
104. Christman K.L., Fok H.H., Sievers R.E., Fang Q., Lee R.J. Fibrin glue alone and skeletal myoblasts in a fibrin scaffold preserve cardiac function after myocardial infarction. Tissue Eng. 2004, 10:403-409.
105. Zhang G., Wang X.H., Wang Z.L., Zhang J., Suggs L.J. A PEGylated fibrin patch for mesenchymal stem cell delivery. Tissue Eng. 2006, 12:9-19.
106. Ryu J.H., Kim I.K., Cho S.W. Implantation of bone marrow mononuclear cells using injectable fibrin matrix enhances neovascularization in infarcted myocardium. Biomaterials 2005, 26:319-326.
107. Dai W., Wold L.E., Dow J.S., Kloner R.A. Thickening of the infarcted wall by collagen injection improves left ventricular function in rats; a novel approach to preserve cardiac function after myocardial infarction. J. Am. Coll. Cardiol. 2005, 46:714-719.
108. Kofidis T., Lebl D.R., Martinez E.C., Hoyt G., Tanaka M., Robbins R.C. Novel injectable bioartificial tissue facilitates targeted, less invasive, large-scale tissue restoration on the beating heart after myocardial injury. Circulation 2005, 112:I173-I177.
109. Kofidis T., de Bruin J.L., Hoyt G. Injectable bioartificial myocardial tissue for large-scale intramural cell transfer and functional recovery of injured heart muscle. J. Thorac. Cardiovasc. Surg. 2004, 128:571-578.
110. Davis M.E., Motion J.P., Narmoneva D.A. Injectable self-assembling peptide nanofibers create intramyocardial microenvironments for endothelial cells. Circulation 2005, 111:442-450.
111. Davis M.E., Hsieh P.C.H., Takahashi T., Song Q., Zhang S., Kamm R.D. Local myocardial insulin-like growth factor 1 (IGF-1) delivery with biotinylated peptide nanofibers improves cell therapy for myocardial infarction. Proc. Natl Acad. Sci. U. S. A 2006, 103:8155-8160.
112. Yeo Y., Geng W.L., Ito T., Kohane D.S., Burdick J.A., Radisic M. Photocrosslinkable hydrogel for myocyte cell culture and injection. J. Biomed. Mater. Res. Part B Appl. Biomater. 2007, 81B:312-322.
113. Landa N., Miller L., Feinberg M.S., Holbova R., Shachar M., Freeman I., et al. Effect of injectable alginate implant on cardiac remodeling and function after recent and old infarcts in rat. Circulation 2008, 117:1388-1396.
114. Leor J., Tuvia S., Guetta V., Manczur F., Castel D., Willenz U., et al. Intracoronary injection of in situ forming alginate hydrogel reverses left ventricular remodeling after myocardial infarction in Swine. J. Am. Coll. Cardiol. 2009, 54:1014-1023.
115. Batista R.J., Verde J., Nery P., Bocchino L., Takeshita N., Bhayana J.N., et al. Partial left ventriculectomy to treat end-stage heart disease. Ann. Thorac. Surg. 1997, 64:634-638.
116. Wall S.T., Walker J.C., Healy K.E., Ratcliffe M.B., Guccione J.M. Theoretical impact of the injection of material into the myocardium - a finite element model simulation. Circulation 2006, 114:2627-2635.
117. Gaudette G.R., Cohen I.S. Cardiac regeneration - materials can improve the passive properties of myocardium, but cell therapy must do more. Circulation 2006, 114:2575-2577.
118. Fujimoto K.L., Ma Z., Nelson D.M., Hashizume R., Guan J., Tobita K., Wagner W.R. Synthesis, characterization and therapeutic efficacy of a biodegradable, thermoresponsive hydrogel designed for application in chronic infarcted myocardium. Biomaterials 2009, 30:4357-4368.
119. Assmus B., Schächinger V., Teupe C., Britten M., Lehmann R., Döbert N., Grünwald F., et al. Transplantation of progenitor cells and regeneration enhancement in acute myocardial infarction (TOPCARE-AMI). Circulation 2002, 106:3009-3017.
120. Schachinger V., Assmus B., Britten M.B., Honold J., Lehmann R., Teupe C., Abolmaali N.D., et al. Transplantation of progenitor cellsandregeneration enhancementin acute myocardial infarction: final one-year results of theTOPCARE-AMITrial. J. Am. Coll. Cardiol. 2004, 44:1690-1699.
121. Chen Q.Z., Bismarck A., Hansen U., Junaid S., Tran M.Q., Harding S.E., et al. Characterisation of a soft elastomer poly(glycerol sebacate) designed to match the mechanical properties of myocardial tissue. Biomaterials 2008, 29:47-57.
122. Simpson D., Liu H., Fan T.H., Nerem R., Dudley S.C. A tissue engineering approach to progenitor cell delivery results in significant cell engraftment and improved myocardial remodeling. Stem Cells 2007, 25:2350-2357.
123. Dvir T., Kedem A., Ruvinov E., Levy O., Freeman I., Landa N., et al. Prevascularization of cardiac patch on the omentum improves its therapeutic outcome. Proc. Natl. Acad. Sci. U. S. A 2009, 106:14990-14995.
124. Radisic M., Park H., Chen F., Salazar-Lazzaro J.E., Wang Y., Dennis R., et al. Biomimetic approach to cardiac tissue engineering: oxygen carriers and channeled scaffolds. Tissue Eng. 2006, 12:2077-2091.
125. Radisic M., Park H., Shing H., Consi T., Schoen F.J., Langer R., Freed L.E., Vunjak-Novakovic G. Functional assembly of engineered myocardium by electrical stimulation of cardiac myocytes cultured on scaffolds. Proc. Natl. Acad. Sci. U. S. A 2004, 101:18129-18134.
126. Zimmermann W.H., Melnychenko I., Eschenhagen T. Engineered heart tissue for regeneration of diseased hearts. Biomaterials 2004, 25:1639-1647.
127. Zimmermann W.H., Melnychenko I., Wasmeier G., Didié M., Naito H., Nixdorff U., et al. Engineered heart tissue grafts improve systolic and diastolic function in infarct rat hearts. Nat. Med. 2006, 12:452-458.
128. Ott H.C., Matthiesen T.S., Goh S.K., Black L.D., Kren S.M., Netoff T.I., Taylor D.A. Perfusion-decellularized matrix: using nature's platform to engineer a bioartificial heart. Nat. Med. 2008, 14:213-221.
129. Zhang G., Hu Q., Braunlin E.A., Suggs L.J., Zhang J. Enhancing efficacy of stem cell transplantation to the heart with a PEGylated fibrin biomatrix. Tissue Eng. Part A 2008, 14:1025-1036.
130. Zhang G., Wang X., Wang Z., Zhang J., Suggs L.J. A PEGylated fibrin patch for mesenchymal stem cell delivery. Tissue Eng. 2006, 12:9-19.
131. Radisic M., Park H., Vunjak-Novakovic G. Cardiac-tissue engineering. Principles of Tissue Engineering 2007, 551-568. Academic Press, Boston. R. Lanza, R. Langer, J. Vacanti (Eds.).
132. Xiang Z., Liao R., Kelly M.S., Spector M. Collagen-GAG scaffolds grafted onto myocardial infarcts in a rat model: a delivery vehicle for mesenchymal stem cells. Tissue Eng. 2006, 12:2467-2478.
133. Li R.K., Jia Z.Q., Weisel R.D., Mickle D.A., Choi A., Yau T.M. Survival and function of bioengineered cardiac grafts. Circulation 1999, 100:II63-II69.
134. Bursac N., Papadaki M., Cohen R.J., Schoen F.J., Eisenberg S.R., Carrier R., Vunjak-Novakovic G., Freed L.E. Cardiac muscle tissue engineering: toward an in vitro model for electrophysiological studies. Am. J. Physiol. 1999, 277:H433-H444.
135. Gerecht-Nir S., Radisic M., Park H., Cannizzaro C., Boublik J., Langer R., Vunjak-Novakovic G. Biophysical regulation during cardiac development and application to tissue engineering. Int. J. Dev. Biol. 2006, 50:233-243.
136. Eschenhagen T., Didié M., Münzel F., Schubert P., Schneiderbanger K., Zimmermann W.H. 3D engineered heart tissue for replacement therapy. Basic Res. Cardiol. 2002, 97:I146-I152.
137. Radisic M., Deen W., Langer R., Vunjak-Novakovic G. Mathematical model of oxygen distribution in engineered cardiac tissue with parallel channel array perfused with culture medium containing oxygen carriers. Am. J. Physiol. Heart Circ. Physiol. 2005, 288:H1278-H1289.
138. Radisic M., Park H., Martens T.P., Salazar-Lazaro J.E., Geng W., Wang Y., et al. Pre-treatment of synthetic elastomeric scaffolds by cardiac fibroblasts improves engineered heart tissue. J. Biomed. Mater. Res. A 2008, 86:713-724.
139. Pego A.P., Siebum B., Van Luyn M.J., Gallego y Van Seijen X.J., Poot A.A., Grijpma D.W., Feijen J. Preparation of degradable porous structures based on 1,3-trimethylene carbonate and D,L-lactide (co)polymers for heart tissue engineering. Tissue Eng. 2003, 9:981-994.
140. Fujimoto K.L., Tobita K., Merryman W.D., Guan J., Sacks M.S., Wagner W.R. An elastic, biodegradable cardiac patch induces contractile smooth muscle and improves cardiac remodeling and function in subacute myocardial infarction. J. Am. Coll. Cardiol. 2007, 49:2292-2300.
141. Fujimoto K.L., Guan J., Oshima H., Sakai T., Wagner W.R. In vivo evaluation of a porous, elastic, biodegradable patch for reconstructive cardiac procedures. Ann. Thorac. Surg. 2007, 83:648-654.
142. Fromstein J.D., Zandstra P.W., Alperin C., Rockwood D., Rabolt J.F., Woodhouse K.A. Seeding bioreactor-produced embryonic stem cell-derived cardiomyocytes on different porous, degradable, polyurethane scaffolds reveals the effect of scaffold architecture on cell morphology. Tissue Eng. Part A 2008, 14:369-378.
143. Eschenhagen T., Fink C., Remmers U., Scholz H., Wattchow J., Weil J., et al. Three-dimensional reconstitution of embryonic cardiomyocytes in a collagen matrix: a new heart muscle model system. FASEB J. 1997, 11(8):683-694.
144. Zimmermann W.H., Didie M., Doker S., Melnychenko I., Naito H., Rogge C., et al. Tissue engineering of a differentiated cardiac muscle construct. Cardiovasc. Res. 2006, 71:419-429.
145. Wang Y., Ameer G.A., Sheppard B.J., Langer R. A tough biodegradable elastomer. Nat. Biotechnol. 2002, 20:602-606.
146. Radisic M., Deen W., Langer R., Vunjak-Novakovic G. Cardiac muscle tissue engineering: toward an in vitro model for electrophysiological studies. Am. J. Physiol. Heart Circ. Physiol. 2005, 288:H1278-H1289.
147. Vunjak-Novakovic G., Radisic M., Obradovic B. Cardiac tissue engineering: effects of bioreactor flow environment on tissue constructs. J. Chem. Technol. Biotechnol. 2006, 81:485-490.
148. Radisic M., Park H., Chen F., Salazar-Lazzaro J.E., Wang Y., Dennis R., et al. Biomimetic approach to cardiac tissue engineering: oxygen carriers and channeled scaffolds. Tissue Eng. 2006, 12:2077-2091.
149. Engelmayr G.C., Cheng M., Bettinger C.J., Borenstein J.T., Langer R., Freed L.E. Accordion-like honeycombs for tissue engineering of cardiac anisotropy. Nat. Mater. 2008, 7:1003-1010.
150. Shin M., Ishii O., Sueda T., Vacanti J.P. Contractile cardiac grafts using a novel nanofibrous mesh. Biomaterials 2004, 25:3717-3723.
151. Rockwood D.N., Jr R.E., Akins I.C.Parrag, Woodhouse K.A., Rabolt J.F. Culture on electrospun polyurethane scaffolds decreases atrial natriuretic peptide expression by cardiomyocytes in vitro. Biomaterials 2008, 29:4783-4791.
152. Pessanha M.G., Mandarim-de-Lacerda C.A. Influence of the chronic nitric oxide synthesis inhibition on cardiomyocytes number. Virchows Arch. 2000, 437:667-674.
153. Giraud M.N., Armbruster C., Carrel T., Tevaearai H.T. Current state of the art in myocardial tissue engineering. Tissue Eng. 2007, 13:1825-1836.
154. Carrier R.L., Papadaki M., Rupnick M., Schoen F.J., Bursac N., Langer R., Freed L.E., Vunjak-Novakovic G. Cardiac tissue engineering: cell seeding, cultivation parameters, and tissue construct characterization. Biotechnol. Bioeng. 1999, 64:580-589.
155. Papadaki M., Bursac N., Langer R., Merok J., Vunjak-Novakovic G., Freed L.E. Tissue engineering of functional cardiac muscle: molecular, structural, and electrophysiological studies. Am. J. Physiol. Heart Circ. Physiol. 2001, 280:H168-H178.
156. Bursac N., Papadaki M., Cohen R.J., Schoen F.J., Eisenberg S.R., Carrier R., Vunjak-Novakovic G., Freed L.E. Cardiac muscle tissue engineering: toward an in vitro model for electrophysiological studies. Am. J. Physiol. 1999, 277:H433-H444.
157. Bursac N., Papadaki M., White J.A., Eisenberg S.R., Vunjak-Novakovic G., Freed L.E. Cultivation in rotating bioreactors promotes maintenance of cardiac myocyte electrophysiology and molecular properties. Tissue Eng. 2003, 9:1243-1253.
158. Carrier R.L., Rupnick M., Langer R., Schoen F.J., Freed L.E., Vunjak-Novakovic G. Perfusion improves tissue architecture of engineered cardiac muscle. Tissue Eng. 2002, 8:175-188.
159. Radisic M., Euloth M., Yang L., Langer R., Freed L.E., Vunjak-Novakovic G. High-density seeding of myocyte cells for cardiac tissue engineering. Biotechnol. Bioeng. 2003, 82:403-413.
160. Radisic M., Deen W., Langer R., Vunjak-Novakovic G. Mathematical model of oxygen distribution in engineered cardiac tissue with parallel channel array perfused with culture medium containing oxygen carriers. Am. J. Physiol. Heart Circ. Physiol. 2005, 288:H1278-H1289.
161. Gerecht-Nir S., Radisic M., Park H., Cannizzaro C., Boublik J., Langer R., et al. Biophysical regulation during cardiac development and application to tissue engineering. Int. J. Dev. Biol. 2006, 50:233-243.
162. Severs N.J. The cardiac muscle cell. Bioessays 2000, 22:188-199.
163. Radisic M., Park H., Shing H., Consi T., Schoen F.J., Langer R., et al. Functional assembly of engineered myocardium by electrical stimulation of cardiac myocytes cultured on scaffolds. Proc. Natl. Acad. Sci. U. S. A 2004, 101:18129-18134.
164. Zimmermann W.H., Melnychenko I., Wasmeier G., Didié M., Naito H., Nixdorff U., et al. Engineered heart tissue grafts improve systolic and diastolic function in infarcted rat hearts. Nat. Med. 2006, 12:452-458.
165. Ott H.C., Matthiesen T.S., Goh S.K., Black L.D., Kren S.M., Netoff T.I., Taylor D.A. Perfusion-decellularized matrix: using nature's platform to engineer a bioartificial heart. Nat. Med. 2008, 14:213-221.
166. Wei H.J., Chen C.H., Lee W.Y., Chiu I., Hwang S.M., Lin W.W., et al. Bioengineered cardiac patch constructed from multilayered mesenchymal stem cells for myocardial repair. Biomaterials 2008, 29:3547-3556.
167. Freed L.E., Engelmayr G.C., Borenstein J.T., Moutos F.T., Guilak F. Advanced material strategies for tissue engineering scaffolds. Adv. Mater. 2009, 21:3410-3418.
168. Badylak S.F. Xenogeneic extracellular matrix as a scaffold for tissue reconstruction. Transpl. Immunol. 2004, 12:367-377.
169. Dai S.Y., Li Z. Enzymatic preparation of novel thermoplastic di-block copolyesters containing poly[(R)-3-hydroxybutyrate] and poly(epsilon-caprolactone) blocks via ring-opening polymerization. Biomacromolecules 2008, 9:1883-1893.
170. Yang J., Webb A.R., Pickerill S.J., Hageman G., Ameer G.A. Synthesis and evaluation of poly(diol citrate) biodegradable elastomers. Biomaterials 2006, 27:1889-1898.
171. Cohn D., Hotovely-Salomon A. Biodegradable multiblock PEO/PLA thermoplastic elastomers: molecular design and properties. Polymer 2005, 46:2068-2075.
172. Pego A.P., Siebum B., Van Luyn M.J.A., Gallego X.J., Van Seijen Y., Poot A.A., Grijma D.W., Feijen J. Preparation of degradable porous structures based on 1, 3-trimethylene carbonate and D, L-lactide (co)polymers for heart tissue engineering. Tissue Eng. 2003, 9:981-994.
173. Yang J., Motlagh D., Webb A.R., Ameer G.A. Novel biphasic elastomeric scaffold for small-diameter blood vessel tissue engineering. Tissue Eng. 2005, 11:1876-1886.
174. Wang Y., Kim Y.M., Langer R. In vivo degradation characteristics of poly(glycerol sebacate). J. Biomed. Mater. Res. A 2003, 66:192-197.
175. Gorna K., Gogolewski S. Biodegradable polyurethanes for implants. II. In vitro degradation and calcification of materials from poly(?-caprolactone)-poly(ethylene oxide) diols and various chain extenders. J. Biomed. Mater. Res. 2002, 60:592-606.
176. Kylma J., Seppala J.V. Synthesis and characterization of a biodegradable thermoplastic poly(ester-urethane) elastomer. Macromolecules 1997, 30:2876-2882.
177. Skarja G.A., Woodhouse K.A. In vitro degradation and erosion of degradable, segmented polyurethanes containing an amino acid-based chain extender. J. Biomater. Sci. Polym. Ed. 2001, 12:851-873.
178. Guelcher S.A., Srinivasan A., Dumas J.E., McBride S., Hollinger J.O. Synthesis, mechanical properties, biocompatibility, and biodegradation of polyurethane networks from lysine polyisocyanates. Biomaterials 2008, 29:1762-1775.
179. Guan J., Sacks M.S., Beckman E.J., Wagner W.R. Synthesis, characterization, and cytocompatibility of efastomeric, biodegradable poly(esterurethane) ureas based on poly(caprolactone) and putrescine. J. Biomed. Mater. Res. 2002, 61:493-503.
180. Guan J., Sacks M.S., Beckman E.J., Wagner W.R. Biodegradable poly(ether ester urethane)urea elastomers based on poly(ether ester) triblock copolymers and putrescine: synthesis, characterization and cytocompatibility. Biomaterials 2004, 25:85-96.
181. Guan J., Wagner W.R. Synthesis, characterization and cytocompatibility of polyurethaneurea elastomers with designed elastase sensitivity. Biomacromolecules 2005, 6:2833-2842.
182. Wang F., Li Z., Lannutti J.L., Wagner W.R., Guan J. Synthesis, characterization and surface modification of low moduli poly(ether carbonate urethane)ureas for soft tissue engineering. Acta Biomater. 2009, 5:2901-2912.
183. Shin M., Ishii O., Sueda T., Vacanti J.P. Contractile cardiac grafts using a novel nanofibrous mesh. Biomaterials 2004, 25:3717-3723.
184. Rockwood D.N., Akins R.E., Parrag I.C., Woodhouse K.A., Rabolt J.F. Culture on electrospun polyurethane scaffolds decreases atrial natriuretic peptide expression by cardiomyocytes in vitro. Biomaterials 2008, 29:4783-4791.
185. Courtney T., Sacks M.S., Stankus J., Guan J., Wagner W.R. Design and analysis of tissue engineering scaffolds that mimic soft tissue mechanical anisotropy. Biomaterials 2006, 27:3631-3638.
186. Richardson T.P., Peters M.C., Ennett A.B., Mooney D.J. Polymeric system for dual growth factor delivery. Nat. Biotechnol. 2001, 19:1029-1034.
187. Sekiya S., Shimizu T., Yamato M., Kikuchi A., Okano T. Bioengineered cardiac cell sheet grafts have intrinsic angiogenic potential. Biochem. Biophys. Res. Commun. 2006, 341:573-582.
188. Shimizu T., Yamato M., Akutsu T., Shibata T., Isoi Y., Kikuchi A., et al. Electrically communicating three-dimensional cardiac tissue mimic fabricated by layered cultured cardiomyocyte sheets. J. Biomed. Mater. Res. 2002, 60:110-117.
189. Shimizu T., Yamato M., Isoi Y., Akutsu T., Setomaru T., Abe K., et al. Fabrication of pulsatile cardiac tissue grafts using a novel 3-dimensional cell sheet manipulation technique and temperature-responsive cell culture surfaces. Circ. Res. 2002, 90:e40.
190. H. Kondoh, Y. Sawa, S. Miyagawa, S. Sakakida-Kitagawa, I.A. Memon, N. Kawaguchi, et al., Longer preservation of cardiac performance by sheet-shaped myoblast implantation in dilated cardiomyopathic hamsters, Cardiovasc. Res. 69(2006) 466-475.
191. Shimizu T., Sekine H., Yang J., Isoi Y., Yamato M., Kikuchi A., et al. Polysurgery of cell sheet grafts overcomes diffusion limits to produce thick, vascularized myocardial tissues. FASEB J. 2006, 20:708-710.
192. Miyahara Y., Nagaya N., Kataoka M., Yanagawa B., Tanaka K., Hao H., et al. Monolayered mesenchymal stem cells repair scarred myocardium after myocardial infarction. Nat. Med. 2006, 12:459-465.
193. Furuta A., Miyoshi S., Itabashi Y., Shimizu T., Kira S., Hayakawa K., et al. Pulsatile cardiac tissue grafts using a novel three-dimensional cell sheet manipulation technique functionally integrates with the host heart, in vivo. Circ. Res. 2006, 98:705-712.
194. Stevens K.R., Kreutziger K.L., Dupras S.K., Korte F.S., Regnier M., Muskheli V., et al. Physiological function and transplantation of scaffold-free and vascularized human cardiac muscle tissue. Proc. Natl. Acad. Sci. U. S. A 2009, 106:16568-16573.