In Vivo Evaluation of a Porous, Elastic, Biodegradable Patch for Reconstructive Cardiac Procedures

Annals of Thoracic Surgery

Volumn 83, Issue 2, 2007, Pages 648-654

  Fujimoto, Kazuro L ^a,b   Guan, Jianjun ^a,b   Oshima, Hideki ^a   Sakai, Tetsuro ^b,c   Wagner, William R ^a,b,c  

^a MCGOWAN INSTITUTE FOR REGENERATIVE MEDICINE   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c University of Pittsburgh   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

POLITEF; POLYESTER URETHANE UREA; POLYMER; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIODEGRADABLE IMPLANT; CELL PROLIFERATION; CONTROLLED STUDY; ENDOTHELIALIZATION; HEALING; HEART RIGHT VENTRICLE OUTFLOW TRACT; HEART SURGERY; HISTOGENESIS; HISTOLOGY; IMPLANTATION; INFLAMMATION; MALE; NONHUMAN; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; RAT; SURVIVAL;

ANIMALS; BIOCOMPATIBLE MATERIALS; CARDIAC SURGICAL PROCEDURES; ELASTICITY; ELASTOMERS; ENDOTHELIUM; EQUIPMENT DESIGN; FIBROBLASTS; IMMUNOHISTOCHEMISTRY; MALE; MICROSCOPY, ELECTRON; MYOCARDIUM; POLYTETRAFLUOROETHYLENE; POLYURETHANES; POROSITY; POSTOPERATIVE PERIOD; PROSTHESES AND IMPLANTS; RATS; RATS, INBRED LEW; VENTRICULAR OUTFLOW OBSTRUCTION;

EID: 33846351214     PISSN: 00034975     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.athoracsur.2006.06.085     Document Type: Article

References (8)

1. Jonas R.A., Freed M.D., Mayer Jr. J.E., and Castaneda A.R. Long-term follow-up of patients with synthetic right heart conduits. Circulation 72 (1985) II77-II83
2. Tang G.H., Fazel S., Weisel R.D., Van Arsdell G.S., and Li R.K. Cardiovascular tissue engineering therapy: so near, so far?. Ann Thorac Surg 79 (2005) 1831-1833
3. Guan J., Sacks M.S., Beckman E.J., and Wagner W.R. Synthesis, characterization, and cytocompatibility of elastomeric, biodegradable poly(ester-urethane)ureas based on poly(caprolactone) and putrescine. J Biomed Mater Res 61 (2002) 493-503
4. Guan J., Fujimoto K.L., Sacks M.S., and Wagner W.R. Preparation and characterization of highly porous, biodegradable polyurethane scaffolds for soft tissue applications. Biomaterials 26 (2005) 3961-3971
5. Sakai T., Li R.K., Weisel R.D., Mickle D.A., Kim E.T., Jia Z.Q., and Yau T.M. The fate of a tissue-engineered cardiac graft in the right ventricular outflow tract of the rat. J Thorac Cardiovasc Surg 121 (2001) 932-942
6. Hibino N., Shin'oka T., and Kurosawa H. Long-term histologic findings in pulmonary arteries reconstructed with autologous pericardium. N Engl J Med 348 (2003) 865-867
7. Ozawa T., Mickle D.A., Weisel R.D., et al. Optimal biomaterial for creation of autologous cardiac grafts. Circulation 106 (2002) I176-I182
8. Guan J., and Wagner W.R. Synthesis, characterization and cytocompatibility of polyurethaneurea elastomers with designed elastase sensitivity. Biomacromolecules 6 (2005) 2833-2842