Cancer stem cells and telomerase as potential biomarkers in veterinary oncology

Veterinary Journal

Volumn 185, Issue 1, 2010, Pages 15-22

  Pang, Lisa Y ^a   Argyle, David ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Biomarkers; Cancer; Stem cells; Telomerase; Veterinary oncology

Indexed keywords

BIOLOGICAL MARKER; TELOMERASE;

CANCER DIAGNOSIS; CANCER GROWTH; CANCER INVASION; CANCER RISK; CANCER STEM CELL; CHROMOSOME SIZE; ENZYME ACTIVITY; ENZYME LOCALIZATION; EPITHELIAL MESENCHYMAL TRANSITION; HUMAN; METASTASIS; NONHUMAN; ONCOLOGY; POLYMERASE CHAIN REACTION; PREDICTION; PROGNOSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVIEW; TARGET CELL; TELOMERIC REPEAT AMPLIFICATION PROTOCOL; VETERINARY MEDICINE;

ANIMALS; DISEASE PROGRESSION; EARLY DETECTION OF CANCER; MEDICAL ONCOLOGY; NEOPLASMS; TELOMERASE; TELOMERE; TUMOR MARKERS, BIOLOGICAL; VETERINARY MEDICINE;

ANIMALIA;

EID: 77953678464     PISSN: 10900233     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tvjl.2010.04.008     Document Type: Review

References (78)

1. Al-Hajj M., Wicha M.S., Benito-Hernandez A., Morrison S.J., Clarke M.F. Prospective identification of tumorigenic breast cancer cells. Proceedings of the National Academy of Sciences USA 2003, 100:3983-3988.
2. Arai T., Yasuda Y., Takaya T., Ito Y., Hayakawa K., Toshima S., Shibuya C., Yoshimi N., Kashiki Y. Application of telomerase activity for screening of primary lung cancer in bronchial alveolar lavage fluid. Oncology Reports 1998, 28:405-408.
3. Argyle D.J., Blacking T. From viruses to cancer stem cells: dissecting the pathways to malignancy. The Veterinary Journal 2008, 177:311-323.
4. Argyle D.J., Nasir L. Telomerase: a potential diagnostic and therapeutic tool in canine oncology. Veterinary Pathology 2003, 40:1-7.
5. Athanassiadou P., Bantis A., Gonidi M., Liossi A., Aggelonidou E., Petrakakou E., Giannopoulos A. Telomerase expression as a marker in prostate cancer: correlation to clinicopathologic predictors. Journal of Experimental and Clinical Cancer Research 2003, 22:613-618.
6. Atlasi Y., Mowla S.J., Ziaee S.A.M., Bahrami A.R. OCT-4, an embryonic stem cell marker, is highly expressed in bladder cancer. International Journal of Cancer 2007, 120:1598-1602.
7. Ault K.A., Allen H.K., Phillips S.L., Zimmerman M.B., Klingelhutz A.J. Telomerase activity as a potential diagnostic marker for triage of abnormal Pap smears. Journal of Lower Genital Tract Disease 2005, 9:93-99.
8. Bene M.C., Kaeda J.S. How and why minimal residual disease studies are necessary in leukemia: a review from WP10 and WP12 of the European Leukaemia Net. Haematologica. The Hematology Journal 2009, 94:1135-1150.
9. Berube N.G., Smith J.R., Pereira-Smith O.M. The genetics of cellular senescence. American Journal of Human Genetics 1998, 62:1015-1019.
10. Blackburn E.H. Structure and function of telomeres. Nature 1991, 350:569-573.
11. Bonnet D., Dick J.E. Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nature Medicine 1997, 3:730-737.
12. Boultwood J., Fidler C., Shepherd P., Watkins F., Snowball J., Haynes S., Kusec R., Gaiger A., Littlewood T.J., Peniket A.J., Wainscoat J.S. Telomere length shortening is associated with disease evolution in chronic myelogenous leukaemia. American Journal of Hematology 1999, 61:5-9.
13. Chaffer C.L., Thompson E.W., Williams E.D. Mesenchymal to epithelial transition in development and disease. Cells Tissues Organs 2007, 185:7-19.
14. Chen X.Q., Bonnefoi H., Pelte M.F., Lyautey J., Lederrey C., Movarekhi S., Schaeffer P., Mulcahy H.E., Meyer P., Stroun M., Anker P. Telomerase RNA as a detection marker in the serum of breast cancer patients. Clinical Cancer Research 2000, 6:3823-3826.
15. Cho R.W., Clarke M.F. Recent advances in cancer stem cells. Current Opinion in Genetics and Development 2008, 18:1-6.
16. Cong Y.S., Wright W.E., Shay J.W. Human telomerase and its regulation. Microbiology and Molecular Biology Review 2002, 66:407-425.
17. Cristofalo V.J., Pignolo R.J. Replicative senescence of human fibroblast like cells in culture. Physiology Review 1993, 73:617-638.
18. Debucquoy A., Goethals L., Libbrecht L., Perneel C., Geboes K., Ectors N., McBride W.H., Haustermans K. Molecular and clinico-pathological markers in rectal cancer: a tissue micro-array study. International Journal of Colorectal Disease 2009, 24:129-138.
19. Diehl F., Schmidt K., Choti M.A., Romans K., Goodman S., Li M., Thornton K., Agrawal N., Sokoll L., Szabo S.A., Kinzler K.W., Vogelstein B., Diaz L.A. Circulating mutant DNA to assess tumor dynamics. Nature Medicine 2008, 14:985-990.
20. Dimri G.P., Lee X.H., Basile G., Acosta M., Scott C., Roskelley C., Medrano E.E., Linskens M., Rubelj I., Pereirasmith O., Peacocke M., Campisi J. A biomarker that identifies senescent human cells in culture and in aging skin in vivo. Proceedings of the National Academy of Sciences USA 1995, 92:9363-9367.
21. Donaldson L., Fordyce C., Gilliland F., Smith A., Feddersen R., Joste N., Moyzis R., Griffith J. Association between outcome and telomere DNA content in prostate cancer. Journal of Urology 1999, 162:1788-1792.
22. Douville J., Beaulieu R., Balicki D. ALDH1 as a functional marker of cancer stem and progenitor cells. Stem Cells and Development 2009, 18:17-26.
23. Driouch K., Landemaine T., Sin S., Wang S.X., Lidereau R. Gene arrays for diagnosis, prognosis and treatment of breast cancer metastasis. Clinical and Experimental Metastasis 2007, 24:575-585.
24. Dumont N., Wilson M.B., Crawford Y.G., Reynolds P.A., Sigaroudinia M., Tlsty T.D. Sustained induction of epithelial to mesenchymal transition activates DNA methylation of genes silenced in basal-like breast cancers. Proceedings of the National Academy of Sciences USA 2008, 105:14867-14872.
25. Fang D., Nguyen T.K., Leishear K., Finko R., Kulp A.N., Hotz S., Van Belle P.A., Xu X.W., Elder D.E., Herlyn M. A tumorigenic subpopulation with stem cell properties in melanomas. Cancer Research 2005, 65:9328-9337.
26. Feng J.L., Funk W.D., Wang S.S., Weinrich S.L., Avilion A.A., Chiu C.P., Adams R.R., Chang E., Allsopp R.C., Yu J.H., Le S.Y., West M.D., Harley C.B., Andrews W.H., Greider C.W., Villeponteau B. The RNA component of human telomerase. Science 1995, 269:1236-1241.
27. Funakoshi Y., Nakayama H., Uetsuka K., Nishimura R., Sasaki N., Doi K. Cellular proliferative and telomerase activity in canine mammary gland tumors. Veterinary Pathology 2000, 37:177-183.
28. Giampieri S., Manning C., Hooper S., Jones L., Hill C.S., Sahai E. Localized and reversible TGF-beta signalling switches breast cancer cells from cohesive to single cell motility. Nature Cell Biology 2009, 11:1287-1296.
29. Gibbs C.P., Kukekov V.G., Reith J.D., Tchigrinova O., Suslov O.N., Scott E.W., Ghivizzani S.C., Ignatova T.N., Steindler D.A. Stem-like cells in bone sarcomas: implications for tumorigenesis. Neoplasia 2005, 7:967-976.
30. Gupta P.B., Onder T.T., Jiang G.Z., Tao K., Kuperwasser C., Weinberg R.A., Lander E.S. Identification of selective inhibitors of cancer stem cells by high-throughput screening. Cell 2009, 138:645-659.
31. Gutova M., Najbauer J., Gevorgyan A.M., Metz M.Z., Weng Y., Shih C., Aboody K.S. Identification of uPAR-positive chemoresistant cells in small cell lung cancer. PLoS ONE 2007, 2:e243.
32. Hahn K.A., Oglivie G., Rusk T., Devauchelle P., Leblanc A., Legendre A., Powers B., Leventhal P.S., Kinet J.P., Palmerini F., Dubreuil P., Moussy A., Hermine O. Masitinib is safe and effective for the treatment of canine mast cell tumors. Journal of Veterinary Internal Medicine 2008, 22:1301-1309.
33. Hakin-Smith V., Jellinek D.A., Levy D., Carroll T., Teo M., Timperley W.R., McKay M.J., Reddel R.R., Royds J.A. Alternative lengthening of telomeres and survival in patients with glioblastoma multiforme. Lancet 2003, 361:836-838.
34. Hartmann U., Brümmendorf T.H., Balabanov S., Thiede C., Illme T., Schaich M. Telomere length and hTERT expression in patients with acute myeloid leukemia correlates with chromosomal abnormalities. Haematologica 2005, 90:307-316.
35. Hayflick L., Moorhead P.S. The serial cultivation of human diploid cell strains. Experimental Cell Research 1961, 25:585-621.
36. Henson J.D., Hannay J.A., McCarthy S.W., Royds J.A., Yeager T.R., Robinson R.A., Wharton S.B., Jellinek D.A., Arbuckle S.M., Yoo J.Y., Robinson B.G., Learoyd D.L., Stalley P.D., Bonar S.F., Yu D.H., Pollock R.E., Reddel R.R. A robust assay for alternative lengthening of telomeres in tumors shows the significance of alternative lengthening of telomeres in sarcomas and astrocytomas. Clinical Cancer Research 2005, 11:217-225.
37. Hermann P.C., Huber S.L., Herrler T., Aicher A., Ellwart J.W., Guba M., Bruns C.J., Heeschen C. Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer. Cell Stem Cell 2007, 1:313-323.
38. Hiyama E., Hiyama K. Telomere and telomerase in stem cells. British Journal of Cancer 2007, 96:1020-1024.
39. Iannolo G., Conticello C., Memeo L., De Maria R. Apoptosis in normal and cancer stem cells. Critical Reviews in Oncology and Hematology 2008, 66:42-51.
40. Ishikawa K., Sasaki A., Haraguchi N., Yoshikawa Y., Mori M. A case of an alpha-fetoprotein-producing intrahepatic cholangiocarcinoma suggests probable cancer stem cell origin. Oncologist 2007, 12:320-324.
41. Kastan M.B., Schlaffer E., Russo J.E., Colvin O.M., Civin C.I., Hilton J. Direct demonstration of elevated aldehyde dehydrogenase in human hematopoietic progenitor cells. Blood 1990, 75:1947-1950.
42. Kim N.W., Piatyszek M.A., Prowse K.R., Harley C.B., West M.D., Ho P.L.C., Coviello G.M., Wright W.E., Weinrich S.L., Shay J.W. Specific association of human telomerase activity with immortal cells and cancer. Science 1994, 266:2011-2015.
43. Kow K., Bailey S.M., Williams E.S., Withrow S., Lana S.E. Telomerase activity in canine osteosarcoma. Veterinary and Comparative Oncology 2006, 4:178-183.
44. Liu R., Wang X.H., Chen G.Y., Dalerba P., Gurney A., Hoey T., Sherlock G., Lewicki J., Shedden K., Clarke M.F. The prognostic role of a gene signature from tumorigenic breast-cancer cells. New England Journal of Medicine 2007, 18:217-226.
45. London C.A., Malpas P.B., Wood-Follis S.L., Boucher J.F., Rusk A.W., Rosenberg M.P., Henry C.J., Mitchener K.L., Klein M.K., Hintermeister J.G., Bergman P.J., Couto G.C., Mauldin G.N., Michels G.M. Multi-center, placebo-controlled, double-blind, randomized study of oral toceranib phosphate (SU11654), a receptor tyrosine kinase inhibitor, for the treatment of dogs with recurrent (either local or distant) mast cell tumor following surgical excision. Clinical Cancer Research 2009, 15:3856-3865.
46. Long S., Argyle D.J., Gault E.A., Campbell S., Nasir L. The canine telomerase catalytic subunit (dogTERT): characterisation of the gene promoter and identification of proximal core sequences necessary for specific transcriptional activity in canine telomerase positive cell lines. Gene 2005, 358:111-120.
47. Lundberg A.S., Hahn W.G., Gupta P., Weinberg R.A. Genes involved in senescence and immortalization. Current Opinion in Cell Biology 2000, 12:705-709.
48. Mani S.A., Guo W., Liao M.J., Eaton E.N., Ayyanan A., Zhou A.Y., Brooks M., Reinhard F., Zhang C.C., Shipitsin M., Campbell L.L., Polyak K., Brisken C., Yang J., Weinberg R.A. The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell 2009, 16:704-715.
49. Meyerson M., Counter C.M., Eaton E.N., Ellisen L.W., Steiner P., Caddle S.D., Ziaugra L., Beijersbergen R.L., Davidoff M.J., Liu Q.Y., Bacchetti S., Haber D.A., Weinberg R.A. HEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization. Cell 1997, 90:785-795.
50. Nakamura T.M., Morin G.B., Chapman K.B., Weinrich S.L., Andrews W.H., Lingner J., Harley C.B., Cech T.R. Telomerase catalytic subunit homologs from fission yeast and human. Science 1997, 277:955-959.
51. Nam H., Chung B.C., Kim Y., Lee K., Lee D. Combining tissue transcriptomics and urine metabolomics for breast cancer biomarker identification. Bioinformatics 2009, 25:3151-3157.
52. Nasir L. Telomeres and telomerase: biological and clinical importance in dogs. The Veterinary Journal 2008, 175:155-163.
53. Nasir L., Devlin P., McKevitt T., Rutteman G., Argyle D.J. Telomere lengths and telomerase activity in dog tissues: a potential model system to study human telomere and telomerase biology. Neoplasia 2001, 3:351-359.
54. Nowell P.C. The clonal evolution of tumor cell populations. Science 1976, 194:23-28.
55. O'Brien C.A., Pollett A., Gallinger S., Dick J.E. A human colon cancer cell capable of initiating tumour growth in immunodeficient mice. Nature 2007, 445:106-110.
56. Ocak S., Chaurand P., Massion P.P. Mass spectrometry-based proteomic profiling of lung cancer. Proceedings of the American Thoracic Society 2009, 6:159-170.
57. Ohyashiki J.H., Ohyashiki K., Fujimura T., Kawakubo K., Shimamoto T., Iwabuchi A., Toyama K. Telomere shortening associated with disease evolution patterns in myelodysplastic syndromes. Cancer Research 1994, 54:3557-3560.
58. Peinado H., Olmeda D., Cano A. Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype?. Nature Reviews Cancer 2007, 7:415-428.
59. Pfeffer U., Romeo F., Noonan D.M., Albini A. Prediction of breast cancer metastasis by genomic profiling: where do we stand?. Clinical and Experimental Metastasis 2009, 26:547-558.
60. Polyak K., Weinberg R.A. Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits. Nature Reviews Cancer 2009, 9:265-273.
61. Poremba C., Scheel C., Hero B., Christiansen H., Schaefer K.L., Nakayama J.I., Berthold F., Juergens H., Boecker W., Dockhorn-Dworniczak B. Telomerase activity and telomerase subunits gene expression patterns in neuroblastoma: a molecular and immunohistochemical study establishing prognostic tools from fresh-frozen and paraffin-embedded tissues. Journal of Clinical Oncology 2000, 17:2582-2592.
62. Prince M.E., Sivanandan R., Kaczorowski A., Wolf G.T., Kaplan M.J., Dalerba P., Weissman I.L., Clarke M.F., Ailles L.E. Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma. Proceedings National Academy of Science USA 2007, 104:973-978.
63. Renwick M.G., Argyle D.J., Long S., Nixon C., Gault E.A., Nasir L. Telomerase activity and telomerase reverse transcriptase catalytic subunit expression in canine lymphoma: correlation with Ki67 immunoreactivity. Veterinary and Comparative Oncology 2006, 4:141-150.
64. Ricci-Vitiani L., Lombardi D.G., Pilozzi E., Biffoni M., Todaro M., Peschle C., De Maria R. Identification and expansion of human colon-cancer-initiating cells. Nature 2007, 445:111-115.
65. Riveros-Rosas H., Julian-Sanchez A., Pina E. Enzymology of ethanol and acetaldehyde metabolism in mammals. Archives of Medical Research 1997, 28:453-471.
66. Rizzo S., Attard G., Hudson D.L. Prostate epithelial stem cells. Cell Proliferation 2005, 38:363-374.
67. Seigel G.M., Campbell L.M., Narayan M., Gonzalez-Fernandez F. Cancer stem cell characteristics in retinoblastoma. Molecular Vision 2005, 11:729-737.
68. Shay J.W., Bacchetti S. A survey of telomerase activity in human cancer. European Journal of Cancer 1997, 33:787-791.
69. Svenson U., Roos G. Telomere length as a biological marker in malignancy. Biochmica et Biophysica ACTA-Molecular Basis of Disease 2009, 1792:317-323.
70. Teske E., Rutteman G.R., Kuipersdijkshoorn N.J. DNA-ploidy and DNA cell characteristics in canine non-Hodgkins-lymphoma. Experimental Haematology 1993, 21:579-584.
71. Uchida N., Buck D.W., He D.P., Reitsma M.J., Masek M., Phan T.V., Tsukamoto A.S., Gage F.H., Weissman I.L. Direct isolation of human central nervous system stem cells. Proceedings of the National Academy of Sciences USA 2000, 97:14720-14725.
72. Ulaner G.A., Huang H.Y., Otero J., Zhao Z.Q., Ben-Porat L., Satagopan J.M., Gorlick R., Meyers P., Healey J.H., Huvos A.G., Hoffman A.R., Ladanyi M. Absence of a telomere maintenance mechanism as a favorable prognostic factor in patients with osteosarcoma. Cancer Research 2003, 63:1759-1763.
73. Woodward W.A., Sulman E.P. Cancer stem cells: markers or biomarkers?. Cancer and Metastasis Reviews 2008, 27:459-470.
74. Yazawa M., Okuda M., Setoguchi A., Nishimura R., Sasaki N., Hasegawa A., Watari T., Tsujimoto H. Measurement of telomerase activity in dog tumors. Journal of Veterinary Medical Sciences 1999, 61:1125-1129.
75. Yazawa M., Okuda M., Setoguchi A., Iwabuchi S., Nishimura R., Sasaki N., Masuda K., Ohno K., Tsujimoto H. Telomere length and telomerase activity in canine mammary gland tumors. American Journal of Veterinary Research 2001, 62:1539-1543.
76. Yin A.H., Miraglia S., Zanjani E.D., Almeida-Porada G., Ogawa M., Leary A.G., Olweus J., Kearney J., Buck D.W. AC133, a novel marker for human hematopoietic stem and progenitor cells. Blood 1997, 90:5002-5012.
77. Yoshida K., Sugino T., Goodison S., Warren B.F., Nolan D., Wadsworth S., Mortensen N.J., Toge T., Tahara E., Tarin D. Detection of telomerase activity in exfoliated cancer cells in colonic luminal washing and its related clinical implications. British Journal of Cancer 1997, 75:207-212.
78. Zheng P.S., Iwasaka T., Zhang Z.M., Pater A., Sugimori H. Telomerase activity in Papanicolaou smear-negative exfoliated cervical cells and its association with lesions and oncogenic human papillomaviruses. Gynecological Oncology 2000, 77:394-398.