Detection of telomerase activity in exfoliated cancer cells in colonic luminal washings and its related clinical implications

British Journal of Cancer

Volumn 75, Issue 4, 1997, Pages 548-553

  Yoshida, K ^a   Sugino, T ^a   Goodison, S ^a   Warren, B F ^b   Nolan, D ^b   Wadsworth, S ^b   Mortensen, N J ^b   Toge, T ^c   Tahara, E ^d   Tarin, D ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b JOHN RADCLIFFE HOSPITAL   (United Kingdom)

^c HIROSHIMA UNIVERSITY   (Japan)

^d HIROSHIMA UNIV SCHOOL OF MEDICINE   (Japan)

Author keywords

Colon carcinoma; Exfoliated cancer cells; Non invasive detection of cancer; Telomerase activity

Indexed keywords

TELOMERASE;

ADULT; AGED; ARTICLE; CANCER CELL; CLINICAL ARTICLE; COLON CARCINOMA; CROHN DISEASE; ENTERITIS; ENZYME ACTIVITY; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; ULCERATIVE COLITIS;

EID: 0038682553     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/bjc.1997.96     Document Type: Article

References (30)

1. Chadeneau C, Hay K, Hirte HW, Gallinger S and Bacchetti S (1995) Telomerase activity associated with acquisition of malignancy in human colorectal cancer. Cancer Res 55: 2533-2536
2. Counter CM, Avilion AA, Lefeuvre CE, Atewart NG, Greider CW, Harley CB and Bacchetti S (1992) Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity. EMBO J 11: 1921-9
3. Counter CM, Hirte HW, Bacchetti S and Harley CB (1994) Telomerase activity in human ovarian carcinoma. Proc Natl Acad Sci USA 91: 2900-2904
4. Fearon ER, Cho KR, Nigro JM, Kern SE, Simons JW, Ruppert JM, Hamilton SR, Preisinger AC, Thomas G, Kinzler K and Vogelstein R (1990a) Identification of a chromosome 18q gene that is altered in colorectal cancers. Science 247: 49-56
5. Fearon ER and Vogelstein B (1990b) A genetic model for colorectal tumorigenesis. Cell 61: 759-767
6. Greider CW (1994) Mammalian telomere dynamics: healing, fragmentation, shortening and stabilization. Current Opin Genet Devel 4: 203-211
7. Greider CW and Blackburn EH (1987) The telomere terminal transferase of Tetrahymena is a ribonucleoprotein enzyme with two kinds of primer specificity. Cell 51: 887-98
8. Harley CB (1991) Telomere loss: mitotic clock or genetic time bomb? Mutation Res 256: 271-282
9. Harley CB, Futcher AB and Greider CW (1990) Telomeres shorten during ageing of human fibroblasts. Nature 345: 458-460
10. Hiyama E, Hiyama K, Yokoyama T, Matsuura Y, Piatyszek MA and Shay JW (1995a) Correlating telomerase activity levels with human neuroblastoma outcome. Nature Med 1: 249-255
11. Hiyama K, Hiyama E, Ishioka S, Yamakido M, Inai K, Gazdar AF, Piatyszek MA and Shay JW (1995b) Telomerase activity in small-cell and non-small-cell lung cancers. J Natl Cancer Inst 87: 895-902
12. Hiyama E, Yokoyama T, Tatsumoto N, Hiyama K, Imamura Y, Murakami Y, Kodama T, Piatyszek MA, Shay JW and Matsuura Y (1995c) Telomerase activity in gastric cancer. Cancer Res 55: 3258-3262
13. Hiyama K, Hirai Y, Kyoizumi S, Akiyama M, Hiyama E, Piatyszek MA, Shay JW, Ishioka S and Yamakido M (1995d) Activation of telomerase in human lymphocytes and hematopoietic progenitor cells. J Immunol 155: 3711-3715
14. Hiyama E, Gollahon L, Kataoka T, Kuroi K, Yokoyama T, Gazdar AF, Hiyama K, Piatyszek MA and Shay JW (1996) Telomerase activity in human breast tumours. J Natl Canncer Inst 87: 116-122
15. Hollstein M, Sidranski D, Vogelstein B and Harris C (1991) p53 mutations in human cancers. Science 253: 49-53
16. Kim NW, Piatyszek MA, Prowse KR, Harley CB, West MD, HO PLC, Coviello GM, Wright WE, Weinrich SL and Shay JW (1994) Specific association of human telomerase activity with immortal cells and cancer. Science 266: 2011-2015
17. Kinzler KW, Nilbert MC, SU L-K, Vogelstein B, Bryan TM, Levy DB, Smith KJ, Preisinger AC, Hedge P, McKechnie D, Finniear R, Markham A, Groffen J, Boguski MS, Altschul SF, Horii A, Ando H, Miyoshi Y, Miki Y, Nishisho I and Nakamura Y (1991a) Identification of FAP locus genes from chromosome 5q21 . Science 253: 661-665
18. Kinzler KW, Nilbert MC, Vogelstein B, Bryan TM, Levy DB, Smith KJ, Preisinger AC, Hamilton SR, Hedge P, Markham A, Carlson M, Joslyn G, Groden J, White R, Miki Y, Miyoshi Y, Nishisho I and Nakamura Y. (1991b) Identification of a gene located at chromosome 5q21 that is mutated in colorectal cancers. Science 251: 1366-1370
19. Langford LA, Piatyszek MA, Xu R, Schold Jr SC and Shay JW (1995) Telomerase activity in human brain tumours. Lancet 346: 1267-1268
20. Leach FS, Nicolaides NC, Papadopoulos N, Liu B, Jen J, Parsons R, Peltomaki P, Sistonen P, Aaltonen LA, Nystrom-Lahti M, Guan X-Y, Zhang Ji, Meltzer PS, YU, J-W, Kao FT, Chen DJ, Cerosaletti KM, Fournier REK, Todd S, Lewis T, Leach RJ, Naylor S, Weissenbach J, Mecklin J-P, Jarvinen H, Petersen GM, Hamilton SR, Green J, Jass J, Watson P, Lynch HT, Trent JM, de la Chapelle A, Kinzler KW and Vogelstein B (1993) Mutations of a muts homolog, in hereditary nonpolyposis colorectal cancer. Cell 75: 1215-1225
21. Li Z-H, Salovaara R, Aaltonen LA and Shihata D (1996) Telomerase activity is commonly detected in hereditary nonpolyposis colorectal cancers. Am J Pathol 148: 1075-1079
22. Matsumura Y, Hanbury D, Smith J and Tarin D (1994) Non-invasive detection of malignancy by identification of unusual CD44 gene activity in exfoliated cancer cells. Br Med J 308: 619-624
23. Morin GB (1989) The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats. Cell 59: 521-529
24. Rhyu MS (1995) Telomeres, telomerase, and immortality. J Natl Cancer Inst 87: 884-894
25. Shay JW, Werbin H and Wright WE (1995) You haven't heard the end of it: telomere loss may link human aging with cancer. Can J Aging 14: 511-524
26. Smith-Ravin J, England J, Talbot IC and Bodmer W (1995) Detection of c-Ki-ras mutations in faecal samples from sporadic colorectal cancer patients. Gut 36: 81-86
27. Sugino T, Yoshida K, Bolodeoku J, Tahara H, Buley I, Manek S, Wells C, Goodison S, Ide T, Suzuki T, Tahara E and Tarin D (1996) Telomerase activity in human breast cancer and benign breast lesions: diagnostic applications in clinical specimens including fine needle aspirates. Int J Cancer 69: 301-306
28. Tahara H, Nakanishi T, Kitamoto M, Nakasho R. Shay JW, Tahara E, Kajiyama G and Ide T (1995a) Telomerase activity in human liver tissues: comparison between chronic liver disease and hepatocellular carcinomas Cancer Res 55: 2734-2736
29. Tahara H, Kuniyasu H, Yasui W, Yokozaki H, Shay JW, Ide T and Tahara E (1995b) Telomerase activity in preneoploastic and neoplastic gastric and colorectal lesions. Clin Cancer Res 1: 1245-1251
30. Yoshida K, Sugino T, Bolodeoku J, Warren BF, Goodison S, Woodman A, Toge T, Tahara E and Tarin D (1996) Detection of exfoliated carcinoma cells in colonic luminal washings by identification of deranged patterns of expression of the CD44 gene. J Clin Pathol 49: 300-305