-
1
-
-
0642303165
-
Continuing increase in the incidence of hepatocellular carcinoma in the United States: an update
-
El-Serag HB, Davila JA, Petersen NJ, McGlynn KA. Continuing increase in the incidence of hepatocellular carcinoma in the United States: an update. Ann Intern Med 2003, 139:817-823.
-
(2003)
Ann Intern Med
, vol.139
, pp. 817-823
-
-
El-Serag, H.B.1
Davila, J.A.2
Petersen, N.J.3
McGlynn, K.A.4
-
2
-
-
0032833628
-
Epidemiology of primary liver cancer
-
10.1055/s-2007-1007117, 10518307
-
Bosch X, Ribes J, Borras J. Epidemiology of primary liver cancer. Semin Liver Dis 1999, 19:271-285. 10.1055/s-2007-1007117, 10518307.
-
(1999)
Semin Liver Dis
, vol.19
, pp. 271-285
-
-
Bosch, X.1
Ribes, J.2
Borras, J.3
-
3
-
-
0141491273
-
Hepatocellular carcinoma
-
10.1016/S0140-6736(03)14964-1, 14667750
-
Llovet JM, Burroughs A, Bruix J. Hepatocellular carcinoma. Lancet 2003, 362:1907-1917. 10.1016/S0140-6736(03)14964-1, 14667750.
-
(2003)
Lancet
, vol.362
, pp. 1907-1917
-
-
Llovet, J.M.1
Burroughs, A.2
Bruix, J.3
-
4
-
-
84919580033
-
Hepatocellular carcinoma and HBV: a prospective study of 22,707 men in Taiwan
-
10.1016/S0140-6736(81)90585-7, 6118576
-
Beasley RP, Hwang LY, Lin CC, Chien CS. Hepatocellular carcinoma and HBV: a prospective study of 22,707 men in Taiwan. Lancet 1981, 2:1129-1132. 10.1016/S0140-6736(81)90585-7, 6118576.
-
(1981)
Lancet
, vol.2
, pp. 1129-1132
-
-
Beasley, R.P.1
Hwang, L.Y.2
Lin, C.C.3
Chien, C.S.4
-
5
-
-
0032800416
-
Aflatoxin as a human carcinogen
-
10.1002/hep.510300231, 10421671
-
Wogan GN. Aflatoxin as a human carcinogen. Hepatology 1999, 30:573-575. 10.1002/hep.510300231, 10421671.
-
(1999)
Hepatology
, vol.30
, pp. 573-575
-
-
Wogan, G.N.1
-
6
-
-
0032828894
-
Hepatitis C virus and hepatocellular carcinoma
-
10.1055/s-2007-1007116, 10518306
-
Colombo M. Hepatitis C virus and hepatocellular carcinoma. Semin Liver Dis 1999, 19:263-269. 10.1055/s-2007-1007116, 10518306.
-
(1999)
Semin Liver Dis
, vol.19
, pp. 263-269
-
-
Colombo, M.1
-
7
-
-
0027769876
-
A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDJ4
-
Serrano M, Hannon GJ, Beach D. A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDJ4. Nature (Lond) 1993, 366:704-707.
-
(1993)
Nature (Lond)
, vol.366
, pp. 704-707
-
-
Serrano, M.1
Hannon, G.J.2
Beach, D.3
-
8
-
-
0028121279
-
A cell cycle regulator potentially involved in genesis of many tumor types
-
10.1126/science.8153634, 8153634
-
Kamb A, Gruis NA, Weaver-Feldhaus J, Liu Q, Harshman K, Tavtigian SV. A cell cycle regulator potentially involved in genesis of many tumor types. Science 1994, 264:436-440. 10.1126/science.8153634, 8153634.
-
(1994)
Science
, vol.264
, pp. 436-440
-
-
Kamb, A.1
Gruis, N.A.2
Weaver-Feldhaus, J.3
Liu, Q.4
Harshman, K.5
Tavtigian, S.V.6
-
9
-
-
0028275733
-
Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers
-
Nobori T, Miura K, Wu DJ, Lois A, Takabayashi K, Carson DA. Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers. Nature (Lond) 1994, 368:753-756.
-
(1994)
Nature (Lond)
, vol.368
, pp. 753-756
-
-
Nobori, T.1
Miura, K.2
Wu, D.J.3
Lois, A.4
Takabayashi, K.5
Carson, D.A.6
-
10
-
-
0029665280
-
Inactivation of p16INK4 in hepatocellular carcinoma
-
10.1002/hep.510240319, 8781327
-
Hui AM, Sakamoto M, Kanai Y, Ino Y, Gotoh M, Yokota J, Hirohashi S. Inactivation of p16INK4 in hepatocellular carcinoma. Hepatology 1996, 24:575-579. 10.1002/hep.510240319, 8781327.
-
(1996)
Hepatology
, vol.24
, pp. 575-579
-
-
Hui, A.M.1
Sakamoto, M.2
Kanai, Y.3
Ino, Y.4
Gotoh, M.5
Yokota, J.6
Hirohashi, S.7
-
11
-
-
0031043705
-
Frequency of mutation and deletion of the tumor suppressor gene CDKN2A (MTS1/p16) in hepatocellular carcinoma from an Australian population
-
10.1002/hep.510250317, 9049204
-
Biden K, Young J, Buttenshaw R, Searle J, Cooksley G, Xu DB, Leggett B. Frequency of mutation and deletion of the tumor suppressor gene CDKN2A (MTS1/p16) in hepatocellular carcinoma from an Australian population. Hepatology 1997, 25:593-597. 10.1002/hep.510250317, 9049204.
-
(1997)
Hepatology
, vol.25
, pp. 593-597
-
-
Biden, K.1
Young, J.2
Buttenshaw, R.3
Searle, J.4
Cooksley, G.5
Xu, D.B.6
Leggett, B.7
-
12
-
-
0030900070
-
Germ-line mutations of the p16INK4(MTS1) gene occur in a subset of patients with hepatocellular carcinoma
-
10.1002/hep.510250613, 9185756
-
Chaubert P, Gayer R, Zimmermann A, Fontolliet C, Stamm B, Bosman F, Shaw P. Germ-line mutations of the p16INK4(MTS1) gene occur in a subset of patients with hepatocellular carcinoma. Hepatology 1997, 25:1376-1381. 10.1002/hep.510250613, 9185756.
-
(1997)
Hepatology
, vol.25
, pp. 1376-1381
-
-
Chaubert, P.1
Gayer, R.2
Zimmermann, A.3
Fontolliet, C.4
Stamm, B.5
Bosman, F.6
Shaw, P.7
-
13
-
-
0034235843
-
P16 is a major inactivation target in hepatocellular carcinoma
-
10.1002/1097-0142(20000701)89:1<60::AID-CNCR9>3.0.CO;2-3, 10897001
-
Baek MJ, Piao Z, Kim N-G, Park C, Shin E-C, Park J-H, Jung H-J, Kim CG, Kim H. p16 is a major inactivation target in hepatocellular carcinoma. Cancer 2000, 89:60-68. 10.1002/1097-0142(20000701)89:1<60::AID-CNCR9>3.0.CO;2-3, 10897001.
-
(2000)
Cancer
, vol.89
, pp. 60-68
-
-
Baek, M.J.1
Piao, Z.2
Kim, N.-G.3
Park, C.4
Shin, E.-C.5
Park, J.-H.6
Jung, H.-J.7
Kim, C.G.8
Kim, H.9
-
14
-
-
0029011539
-
5' CpG island methylation is associated with transcriptional silencing of the tumor suppressor p16/CDKN2/MTS1 in human cancers
-
10.1038/nm0795-686, 7585152
-
Merlo A, Herman JG, Mao L, Lee DJ, Gabrielson E, Burger PC. 5' CpG island methylation is associated with transcriptional silencing of the tumor suppressor p16/CDKN2/MTS1 in human cancers. Nat Med 1995, 1:686-692. 10.1038/nm0795-686, 7585152.
-
(1995)
Nat Med
, vol.1
, pp. 686-692
-
-
Merlo, A.1
Herman, J.G.2
Mao, L.3
Lee, D.J.4
Gabrielson, E.5
Burger, P.C.6
-
15
-
-
0032924622
-
P16INK4 is inactivated by extensive CpG methylation in human hepatocellular carcinoma
-
10.1016/S0016-5085(99)70137-X, 9922321
-
Matsuda Y, Ichida T, Matsuzawa J, Sugimura K, Asakura H. p16INK4 is inactivated by extensive CpG methylation in human hepatocellular carcinoma. Gastroenterology 1999, 116:394-400. 10.1016/S0016-5085(99)70137-X, 9922321.
-
(1999)
Gastroenterology
, vol.116
, pp. 394-400
-
-
Matsuda, Y.1
Ichida, T.2
Matsuzawa, J.3
Sugimura, K.4
Asakura, H.5
-
16
-
-
0035056507
-
Detection of hypermethylation of the p16INK4a promoter in chronic hepatitis and cirrhosis associated with hepatitis B or C virus
-
10.1136/gut.48.3.372, 1760137, 11171828
-
Kaneto H, Sasaki S, Yamamoto H, Itoh F, Toyota M, Suzuki H, Ozeki I, Iwata N, Ohmura T, Satoh T, Karino Y, Satoh T, Toyota J, Satoh M, Endo T, Omata M, Imai K. Detection of hypermethylation of the p16INK4a promoter in chronic hepatitis and cirrhosis associated with hepatitis B or C virus. Gut 2001, 48:372-377. 10.1136/gut.48.3.372, 1760137, 11171828.
-
(2001)
Gut
, vol.48
, pp. 372-377
-
-
Kaneto, H.1
Sasaki, S.2
Yamamoto, H.3
Itoh, F.4
Toyota, M.5
Suzuki, H.6
Ozeki, I.7
Iwata, N.8
Ohmura, T.9
Satoh, T.10
Karino, Y.11
Satoh, T.12
Toyota, J.13
Satoh, M.14
Endo, T.15
Omata, M.16
Imai, K.17
-
17
-
-
21644473614
-
P16INK4a hypermethylation is associated with hepatitis virus infection, age, and gender in hepatocellular carcinoma
-
10.1158/1078-0432.CCR-04-1715, 15569978
-
Li X, Hui A-M, Sun L, Hasegawa K, Torzilli G, Minagawa M, Takayama T, Makuuchi M. p16INK4a hypermethylation is associated with hepatitis virus infection, age, and gender in hepatocellular carcinoma. Clin Cancer Res 2004, 10:7484-7489. 10.1158/1078-0432.CCR-04-1715, 15569978.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 7484-7489
-
-
Li, X.1
Hui, A.-M.2
Sun, L.3
Hasegawa, K.4
Torzilli, G.5
Minagawa, M.6
Takayama, T.7
Makuuchi, M.8
-
18
-
-
0029843950
-
Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands
-
10.1073/pnas.93.18.9821, 38513, 8790415
-
Herman JG, Graff JR, Myohanen S, Nelkin BD, Baylin SB. Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands. Proc Natl Acad Sci USA 1996, 93:9821-9826. 10.1073/pnas.93.18.9821, 38513, 8790415.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 9821-9826
-
-
Herman, J.G.1
Graff, J.R.2
Myohanen, S.3
Nelkin, B.D.4
Baylin, S.B.5
-
19
-
-
0034654669
-
Methy-Light: a high-throughput assay to measure DNA methylation
-
10.1093/nar/28.8.e32, 102836, 10734209
-
Eads CA, Danenberg KD, Kawakami K, Saltz LB, Blake C, Shibata D, Danenberg PV, Laird PW. Methy-Light: a high-throughput assay to measure DNA methylation. Nucleic Acid Res 2000, 28:E32. 10.1093/nar/28.8.e32, 102836, 10734209.
-
(2000)
Nucleic Acid Res
, vol.28
-
-
Eads, C.A.1
Danenberg, K.D.2
Kawakami, K.3
Saltz, L.B.4
Blake, C.5
Shibata, D.6
Danenberg, P.V.7
Laird, P.W.8
-
20
-
-
0034665332
-
Fields of aberrant CpG island hypermethylation in Barrett's esophagus and associated adenocarcinoma
-
Eads CA, Lord RV, Kurumboor SK, Wickramasinghe K, Skinner ML, Long TI, Peters JH, DeMeester TR, Danenberg KD, Danenberg PV, Laird PW, Skinner KA. Fields of aberrant CpG island hypermethylation in Barrett's esophagus and associated adenocarcinoma. Cancer Res 2000, 60:5021-5026.
-
(2000)
Cancer Res
, vol.60
, pp. 5021-5026
-
-
Eads, C.A.1
Lord, R.V.2
Kurumboor, S.K.3
Wickramasinghe, K.4
Skinner, M.L.5
Long, T.I.6
Peters, J.H.7
DeMeester, T.R.8
Danenberg, K.D.9
Danenberg, P.V.10
Laird, P.W.11
Skinner, K.A.12
-
21
-
-
78651053628
-
Primary carcinoma of the liver: a study of 100 cases among 48,900 necropsies
-
10.1002/1097-0142(195405)7:3<462::AID-CNCR2820070308>3.0.CO;2-E, 13160935
-
Edmondson HA, Steiner PE. Primary carcinoma of the liver: a study of 100 cases among 48,900 necropsies. Cancer 1954, 7:462-503. 10.1002/1097-0142(195405)7:3<462::AID-CNCR2820070308>3.0.CO;2-E, 13160935.
-
(1954)
Cancer
, vol.7
, pp. 462-503
-
-
Edmondson, H.A.1
Steiner, P.E.2
-
22
-
-
0004149315
-
Pathology of the liver
-
Edinburgh, London Churchill Livingstone
-
MacSween RNM, Burt AD, Portman BC, Ishak KG, Scheuer PJ, Anthony PP. Pathology of the liver. 2002, Edinburgh, London Churchill Livingstone.
-
(2002)
-
-
MacSween, R.N.M.1
Burt, A.D.2
Portman, B.C.3
Ishak, K.G.4
Scheuer, P.J.5
Anthony, P.P.6
-
23
-
-
0029039362
-
Histological grading and staging of chronic hepatitis
-
Ishak K, Baptista A, Bianchi L, Cellea F, De Groote J, Gudat F, Denk H, Desmet V, Korb G, MacSween RNM, Phillips MJ, Portmann BG, Poulsen H, Scheuer PJ, Schmid M, Thaler H. Histological grading and staging of chronic hepatitis. J Hepatol 1995, 22:966-969.
-
(1995)
J Hepatol
, vol.22
, pp. 966-969
-
-
Ishak, K.1
Baptista, A.2
Bianchi, L.3
Cellea, F.4
De Groote, J.5
Gudat, F.6
Denk, H.7
Desmet, V.8
Korb, G.9
MacSween, R.N.M.10
Phillips, M.J.11
Portmann, B.G.12
Poulsen, H.13
Scheuer, P.J.14
Schmid, M.15
Thaler, H.16
-
24
-
-
0038135028
-
Loss of beta-catenin expression in metastatic gastric cancer
-
10.1200/JCO.2003.10.017, 12721245
-
Ebert MP, Yu J, Hoffmann J, Rocco A, Rocken C, Kahmann S, Muller O, Korc M, Sung JJ, Malfertheiner P. Loss of beta-catenin expression in metastatic gastric cancer. J Clin Oncol 2003, 21:1708-1714. 10.1200/JCO.2003.10.017, 12721245.
-
(2003)
J Clin Oncol
, vol.21
, pp. 1708-1714
-
-
Ebert, M.P.1
Yu, J.2
Hoffmann, J.3
Rocco, A.4
Rocken, C.5
Kahmann, S.6
Muller, O.7
Korc, M.8
Sung, J.J.9
Malfertheiner, P.10
-
25
-
-
33644686386
-
Hypermethylation of the TPEF/HPP1 gene in primary and metastatic colorectal cancers
-
10.1593/neo.05235, 1501884, 16207479
-
Ebert MPA, Mooney SH, Tonnes-Priddy L, Lograsso J, Hoffmann J, Chen J, Röcken C, Schulz H-U, Malfertheiner P, Lofton-Day C. Hypermethylation of the TPEF/HPP1 gene in primary and metastatic colorectal cancers. Neoplasia 2005, 7:771-778. 10.1593/neo.05235, 1501884, 16207479.
-
(2005)
Neoplasia
, vol.7
, pp. 771-778
-
-
Ebert, M.P.A.1
Mooney, S.H.2
Tonnes-Priddy, L.3
Lograsso, J.4
Hoffmann, J.5
Chen, J.6
Röcken, C.7
Schulz, H.-U.8
Malfertheiner, P.9
Lofton-Day, C.10
-
26
-
-
3042522794
-
Differences in loss of p16INK4 protein expression by promoter methylation between left- and right-sided primary colorectal carcinomas
-
Schneider-Stock R, Boltze C, Peters B, Höpfner T, Meyer F, Lippert H, Roessner A. Differences in loss of p16INK4 protein expression by promoter methylation between left- and right-sided primary colorectal carcinomas. Int J Oncol 2003, 23:1009-1013.
-
(2003)
Int J Oncol
, vol.23
, pp. 1009-1013
-
-
Schneider-Stock, R.1
Boltze, C.2
Peters, B.3
Höpfner, T.4
Meyer, F.5
Lippert, H.6
Roessner, A.7
-
27
-
-
0037455979
-
P16 hypermethylation in the early stage of hepatitis B virus-associated hepatocarcinogenesis
-
10.1016/S0304-3835(02)00613-4, 12565176
-
Shim Y-H, Yoon G-S, Choi H-J, Chung YH, Yu E. p16 hypermethylation in the early stage of hepatitis B virus-associated hepatocarcinogenesis. Cancer Lett 2003, 190:213-219. 10.1016/S0304-3835(02)00613-4, 12565176.
-
(2003)
Cancer Lett
, vol.190
, pp. 213-219
-
-
Shim, Y.-H.1
Yoon, G.-S.2
Choi, H.-J.3
Chung, Y.H.4
Yu, E.5
-
28
-
-
0242361564
-
Inactivation of p16INK4a by CpG hypermethylation is not a frequent event in colorectal cancer
-
10.1002/jso.10310, 14598358
-
Norrie MWA, Hawkins NJ, Todd AV, Meagher AP, O'Connor TW, Ward RL. Inactivation of p16INK4a by CpG hypermethylation is not a frequent event in colorectal cancer. J Surg Oncol 2003, 84:143-150. 10.1002/jso.10310, 14598358.
-
(2003)
J Surg Oncol
, vol.84
, pp. 143-150
-
-
Norrie, M.W.A.1
Hawkins, N.J.2
Todd, A.V.3
Meagher, A.P.4
O'Connor, T.W.5
Ward, R.L.6
-
29
-
-
33646158891
-
P16INK4a promoter methylation and 9p21 allelic loss in colorectal carcinomas: relation with immunohistochemical p16INK4a expression and tumor budding
-
Prall FP, Ostwald C, Weirich V, Nizze H. p16INK4a promoter methylation and 9p21 allelic loss in colorectal carcinomas: relation with immunohistochemical p16INK4a expression and tumor budding. Human Pathol 2006, 37:578-585.
-
(2006)
Human Pathol
, vol.37
, pp. 578-585
-
-
Prall, F.P.1
Ostwald, C.2
Weirich, V.3
Nizze, H.4
-
30
-
-
0029993450
-
Role of the INK4a locus in tumor suppression and cell mortality
-
10.1016/S0092-8674(00)81079-X, 8620534
-
Serrano M, Lee H, Chin L, Cordon-Cardo C, Beach D, DePinho RA. Role of the INK4a locus in tumor suppression and cell mortality. Cell 1996, 85:27-37. 10.1016/S0092-8674(00)81079-X, 8620534.
-
(1996)
Cell
, vol.85
, pp. 27-37
-
-
Serrano, M.1
Lee, H.2
Chin, L.3
Cordon-Cardo, C.4
Beach, D.5
DePinho, R.A.6
-
31
-
-
0030612349
-
Expression of the p16INK4a tumor suppressor versus other INK4 family members during mouse development and aging
-
10.1038/sj.onc.1201178, 9244355
-
Zindy F, Quelle DE, Roussel MF, Sherr CJ. Expression of the p16INK4a tumor suppressor versus other INK4 family members during mouse development and aging. Oncogene 1997, 15:203-211. 10.1038/sj.onc.1201178, 9244355.
-
(1997)
Oncogene
, vol.15
, pp. 203-211
-
-
Zindy, F.1
Quelle, D.E.2
Roussel, M.F.3
Sherr, C.J.4
-
32
-
-
0033778763
-
P16INK4a expression begins early in human colon neoplasia and correlates inversely with markers of cell proliferation
-
10.1053/gast.2000.17952, 11040180
-
Dai CY, Furth EE, Mick R, Koh J, Takayama T, Niitsu Y, Enders GH. p16INK4a expression begins early in human colon neoplasia and correlates inversely with markers of cell proliferation. Gastroenterology 2000, 119:929-942. 10.1053/gast.2000.17952, 11040180.
-
(2000)
Gastroenterology
, vol.119
, pp. 929-942
-
-
Dai, C.Y.1
Furth, E.E.2
Mick, R.3
Koh, J.4
Takayama, T.5
Niitsu, Y.6
Enders, G.H.7
-
33
-
-
0033638229
-
Human colorectal cancers with an intact p16/cyclinD/pRb pathway have up-regulated p16 expression and decreased proliferation in small invasive tumor clusters
-
Palmqvist R, Rutegard JN, Bozoky B, Landberg G, Stenling R. Human colorectal cancers with an intact p16/cyclinD/pRb pathway have up-regulated p16 expression and decreased proliferation in small invasive tumor clusters. Am J Pathol 2000, 157:1947-1953.
-
(2000)
Am J Pathol
, vol.157
, pp. 1947-1953
-
-
Palmqvist, R.1
Rutegard, J.N.2
Bozoky, B.3
Landberg, G.4
Stenling, R.5
-
34
-
-
0033995386
-
Expression of tumor suppressor gene p16(INK4) products in primary gastric cancer
-
10.1159/000012089, 10705239
-
Tsujie M, Yamamoto H, Tomita N, Sugita Y, Ohue M, Sakita I. Expression of tumor suppressor gene p16(INK4) products in primary gastric cancer. Oncology 2000, 58:126-136. 10.1159/000012089, 10705239.
-
(2000)
Oncology
, vol.58
, pp. 126-136
-
-
Tsujie, M.1
Yamamoto, H.2
Tomita, N.3
Sugita, Y.4
Ohue, M.5
Sakita, I.6
|