Hepatitis C virus and hepatocellular carcinoma

Seminars in Liver Disease

Volumn 19, Issue 3, 1999, Pages 263-269

  Colombo, Massimo ^a  

^a UNIVERSITY OF MILAN   (Italy)

Author keywords

Cirrhosis; Hepatitis C virus; Hepatocellular carcinoma

Indexed keywords

RNA DIRECTED DNA POLYMERASE;

ARTICLE; CANCER MORTALITY; CANCER RISK; CELL INTERACTION; DEVELOPED COUNTRY; DISEASE ASSOCIATION; DISEASE COURSE; HEPATITIS C; HUMAN; LIVER CARCINOGENESIS; LIVER CELL CARCINOMA; LIVER CIRRHOSIS; PRIORITY JOURNAL; RISK FACTOR; TUMOR GROWTH;

EID: 0032828894     PISSN: 02728087     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2007-1007116     Document Type: Article

References (83)

1. Bosch FX, Munoz N. Hepatocellular carcinoma in the world: epidemiologic questions. In: E Tabor, AM Di Bisceglie, RH Purcell, eds. Etiology, Pathology and Treatment of Hepatocellular Carcinoma in North America. Houston, TX: Gulf Publishing Company, 1991, pp 35-54
2. Okuda K. Hepatitis C virus and hepatocellular carcinoma. In: K Okuda, ed. Liver Cancer. New York: Churchill Livingstone, 1997, pp 39-49
3. Okuda K, Fujimoto I, Hanai A, Urano Y. Changing incidence of hepatocellular carcioma in Japan. Cancer Res 1987;47:4697-4672
4. Bellentani S, Tiribelli C, Saccoccio G, et al. Prevalence of chronic liver disease in the general population of Northern Italy: the Dionysos study. Hepatology 1994;20:1442-1449
5. Kiyosawa K, Akahana Y, Nagata A, Furuta S. Hepatocellular carcinoma after non-A, non-B post-transfusion hepatitis. Am J Gastroenterol 1984;79:777-781
6. Ayoola EA, Odelola HA, Johnson AOK. Primary liver cancer (PLC) after non-A, non-B hepatits (NANBH). Hepatology 1982;2:A154
7. Resnick RH, Stone K, Antonioli D. Primary hepatocellular carcinoma following non-A, non-B post-transfusion hepatitis. Dig Dis Sci 1983;28:908-911
8. Gilliam JH, Geisinger KR, Richter JE. Primary hepatocellular carcinoma after chronic non-A, non-B post-transfusion hepatitis. Ann Intern Med 1984;101:794-795
9. Kiyosawa K, Sodeyama T, Tanaka E, et al. Interrelationship of blood transfusion, non-A, non-B hepatitis and hepatocellular carcinoma: analysis by detection of antibody to hepatitis C virus. Hepatology 1990;12:671-675
10. Tradati F, Colombo M, Mannucci PM, et al. A prospective multicenter study of hepatocellular carcinoma in Italian hemophiliacs with chronic hepatitis C. Blood 1998;91: 1173-1177
11. Bruix J, Barrera JM, Calvet X, et al. Prevalence of antibodies to hepatitis C virus in Spanish patients with hepatocellular carcinoma and hepatic cirrhosis. Lancet 1989;2:1004-1006
12. Colombo M, Kuo G, Choo QL, et al. Prevalence of antibodies to hepatitis C virus in Italian patients with hepatocellular carcinoma. Lancet 1989;2:1006-1008
13. Chen DS, Kuo GC, Sung JL, et al. Hepatitis C virus infection in an area hyperendemic for hepatitis B and chronic liver disease: the Taiwan experience. J Infect Dis 1991;162:817-822
14. Dazza MC, Meneses LV, Girard PM, Villaroel C, Brechot C, Larouze B. Hepatitis C antibody and hepatocellular carcinoma. Lancet 1990;1:1216
15. Hasan F, Jeffers LJ, De Medina M, et al. Hepatitis C-associated hepatocellular carcinoma. Hepatology 1990;12:589-591
16. Kaklamani E, Trichopoulos D, Tzonou A, et al. Hepatitis B and C viruses and their interaction in the origin of hepatocellular carcinoma. JAMA 1991;265:1974-1976
17. Kew MC, Houghton M, Choo QL, Kuo G. Hepatitis C virus antibodies in Southern African blacks with hepatocellular carcinoma. Lancet 1990;1:873-874
18. Nishioka K, Watanabe J, Furuta S, et al. A high prevalence of antibody to the hepatitis C virus in patients with hepatocellular carcinoma in Japan. Cancer 1991;67:429-433
19. Poynard T, Aubert A, Lazizi Y, et al. Independent risk factors for hepatocellular carcinoma in French drinkers. Hepatology 1991;13:896-901
20. Saito I, Miyamura T, Ohbayashi A, et al. Hepatitis C virus infection is associated with the development of hepatocellular carcinoma. Proc Natl Acad Sci USA 1990;87:6547-6549
21. Srivantanakul P, Parkin DM, Khlat M, et al. Liver cancer in Thailand. II. A case control study of hepatocellular carcinoma. Int J Cancer 1991;48:329-332
22. Vargas V, Castells L, Esteban JI. High frequency of antibodies to hepatitis C virus among patients with hepatocellular carcinoma. Ann Intern Med 1990;112:232-233
23. Yu MC, Tong MJ, Coursaget P, Ross RK, Govindarajan S, Henderson BE. Prevalence of hepatitis B and C viral markers in black and white patients with hepatocellular carcinoma in the United States. J Natl Cancer Inst 1990;82:1038-1041
24. Ohkoshi S, Kato N, Kinoshita T, et al. Detection of hepatitis C virus RNA in sera and liver tissues of non-A, non-B hepatitis patients using the polymerase chain reaction. Jpn J Cancer Res 1990;81:862-865
25. Shibata M, Takeda S, Kudo T, et al. Minus strand RNA of hepatitis C virus in liver tissues. J Hepatol 1991;13:379-380
26. Tang L, Tanaka Y, Enomoto N, Marumo F, Sato C. Detection of hepatitis C virus RNA in hepatocellular carcinoma by in situ hybridization. Cancer 1995;76:2211-2216
27. Donate F, Boffetta P, Puoti M. A meta-analysis of epidemiological studies on the combined effect of hepatitis B and C virus infections in causing hepatocellular carcinoma. Int J Cancer 1998;75:347-354
28. Donato F, Tagger A, Chiesa R, et al. Hepatitis B and C virus infection, alcohol drinking, and hepatocellular carcinoma: a case control study in Italy. Hepatology 1997;26:579-584
29. Tsukuma H, Hiyama T, Tanaka S, et al. Risk factors for hepatocellular carcinoma among patients with chronic liver disease. N Engl J Med 1993;328:1797-1801
30. Colombo M, de Franchis R, Del Ninno E, et al. Hepatocellular carcinoma in Italian patients with cirrhosis. N Engl J Med 1991;325:675-680
31. De Mitri MS, Poussin K, Baccarini P, et al. HCV-associated liver cancer without cirrhosis. Lancet 1995;345:413-415
32. Simmonds P, Alberti A, Alter JH, et al. A proposed system for the nomenclature of hepatitis C viral genotypes. Hepatology 1994;19:1321-1324
33. Takano S, Yokosuka O, Imazeki F, Tagawa M, Omata M. Incidence of chronic hepatitis B and C. A prospective study of 251 patients. Hepatology 1995;21:650-655
34. Romeo R, Rumi MG, Del Ninno E, Colombo M. Hepatitis C virus genotype 1b and risk of hepatocellular carcinoma. Hepatology 1997;26:1077
35. Bruno S, Silini E, Crosignani A, et al. Hepatitis C virus genotypes and risk of hepatocellular carcinoma in cirrhosis: a prospective study. Hepatology 1997;25:754-758
36. Tarao K, Ohkawa S, Shimizu A, et al. Significance of hepatocellular proliferation in the development of hepatocellular carcinoma from anti-hepatitis C virus positive cirrhotic patients. Cancer 1994;73:1149-1154
37. Borzio M, Treré D, Borzio F, et al. Hepatocyte proliferation rate is a powerful parameter for predicting hepatocellular carcinoma development in liver cirrhosis. J Clin Pathol Mol Pathol 1998;51:96-101
38. Donato MF, Arosio E, Balestrieri M, et al. Increased risk of hepatocellular carcinoma (HCC) in cirrhotic patients with high proliferating cellular nuclear antigen index (PCNA-I). Ital J Gastroenterol 1998;20(Suppl 1):A66
39. Borzio M, Bruno S, Roncalli M, et al. Liver cell dysplasia is a major risk factor for hepatocellular carcinoma in cirrhosis: A prospective study. Gastroenterology 1995;108:812-817
40. Shibata M, Morizane T, Uchida T, et al. Irregular regeneration of hepatocytes and risk of hepatocellular carcinoma in chronic hepatitis and cirrhosis with hepatitis-C-virus infection. Lancet 1998;351:1773-1777
41. Sato Y, Nakata K, Kato Y, et al. Early recognition of hepatocellular carcinoma based on altered profiles of alpha-fetoprotein. N Engl J Med 1993;328:1802-1806
42. Benvegnù L, Fattovich G, Noventa V, et al. Concurrent hepatitis B and C virus infection and risk of hepatocellular carcinoma in cirrhosis: a prospective study. Cancer 1994;74:2442-2448
43. Austin H. The role of tobacco use and alcohol consumption in the etiology of hepatocellular carcinoma. In: E Tabor, AM Di Bisceglie, RH Purcell, eds. Etiology, Pathology and Treatment of Hepatocellular Carcinoma in North America. The Woodlands, TX: Portfolio, 1991, pp 57-75
44. Yamauchi M, Nakahara M, Maezawa Y, et al. Prevalence of hepatocellular carcinoma in patients with alcoholic cirrhosis and prior exposure to hepatitis C. Am J Gasteroenterol 1993;88:39-43
45. Nishiguchi S, Kuroki T, Nakatani S, et al. Randomised trial of effects of interferon-α on incidence of hepatocellular carcinoma in chronic active hepatitis C with cirrhosis. Lancet 1995;346: 1051-1055
46. International Interferon-α Hepatocellular Carcinoma Study Group. Effect of interferon-a on progression of cirrhosis to hepatocellular carcinoma: a retrospective cohort study. Lancet 1998; 351:1535-1539
47. Kasahara A, Hayashi N, Mochizuki K, et al. Risk factors for hepatocellular carcinoma and its incidence after interferon treatment in patients with chronic hepatitis C. Hepatology 1998;27: 1394-1402
48. Lau GKK, Davis GL, Wu SPC, Gish RG, Balart LA, Lau JYN. Hepatic expression of hepatitis C virus RNA in chronic hepatitis C: a study by in situ reverse-transcription polymerase chain reaction. Hepatology 1996;23:1318-1323
49. Ballardini G, Groff P, Giostra F, et al. Hepatocellular codistribution of c100, c33, c22, and NS5 hepatitis C virus antigens detected by using immunopurified polyclonal spontaneous human antibodies. Hepatology 1995;21:730-734
50. Ravaggi A, Natoli G, Primi D, Albertini A, Levrero M, Cariani E. Intracellular localization of full-length and truncated hepatitis C virus core protein expressed in mammalian cells. J Hepatol 1994;20:833-836
51. Shih CM, Lo SJ, Miyamura T, Chen SY, Lee YW. Suppression of hepatitis B virus expression and replication by hepatitis C virus core protein in HUH-7 cells. J Virol 1993;67:5823-5832
52. Lo SY, Selby MJ, Ou JH. Interaction between hepatitis C virus core protein and E1 envelope protein. J Virol 1998;70:5177-5182
53. Ray RN, Lagging LM, Meyer K, Steele R, Ray R. Transcription regulation of cellular and viral promoters by the hepatitis C virus core protein. Virus Res 1996;37:209-220
54. Ray RB, Lagging LM, Meyer K, Ray R. Hepatitis C virus core protein cooperates with ras and transforms primary rat embryo fibroblasts to tumorigenic phenotype. J Virol 1996;70:4438-4443
55. Hiramatsu H, Hayashi N, Katayama K, et al. Immunohistochemical detection of Fas antigen in liver tissue of patients with chronic hepatitis C. Hepatology 1994;19:1354-1359
56. Ray RB, Meyer K, Ray R. Suppression of apoptotic cell death by hepatitis C virus core protein. Virology 1996;226:178-182
57. Ray RB, Steel R, Meyer K, Ray R. Transcriptional repression of p53 promoter by hepatitis C virus core protein. J Biol Chem 1997;272:10983-10986
58. Moriya K, Fujie H, Shintani Y, et al. The core protein of hepatitis C virus induces hepatocellular carcinoma in transgenic mice. Nat Med 1998;4:1065-1067
59. Kawamura T, Furusaka A, Koziel MJ, et al. Transgenic expression of hepatitis C virus structural proteins in the mouse. Hepatology 1997;25:1014-1021
60. Pasquinelli C, Shoenberger JM, Chung J, et al. Hepatitis C virus core and E2 protein expression in transgenic mice. Hepatology 1997;25:719-727
61. Sakamuro D, Furukawa T, Takenagi TJ. Hepatitis C virus non structural protein NS3 transforms NIH 3T3 cells. J Virol 1995; 69:3893-3896
62. Antony PP. Primary carcinoma of the liver. A study of 282 cases in Ugandan Africans. J Pathol 1973;110:37-48
63. Takenaka K, Adachi E, Nishizaki T, et al. Possible multicentric occurrence of hepatocellular carcinoma: a clinicopathological study. Hepatology 1994;19:889-894
64. Fasani P, Sangiovanni A, De Fazio C, et al. High prevalence of multinodal hepatocellular carcinoma in patients with cirrhosis due to multiple etiological factors. Hepatology 1999;29:1704-1707.
65. Benvegnù L, Chemello L, Bernardinello E, Cavalletto L, Alberti A. Evidence for an association between etiology of cirrhosis and pattern of hepatocellular carcinoma (HCC) development. Ital J Gastroenterol Hepatol 1998;30(Suppl 1):A66
66. Ebara M, Ohio M, Kondo F. Strategy for early diagnosis of hepatocellular carcinoma (HCC). Ann Acad Med Singapore 1989; 18:83-89
67. Gozzetti G, Belli L, Capussotti L, et al. Liver resection for hepatocellular carcinoma in cirrhotic patients. Ital J Gastroenterol 1992;24:105-110
68. Franco D, Capussotti L, Smadja C, et al. Resection of hepatocellular carcinomas. Results in 72 European patients with cirrhosis. Gastroenterology 1990;98:733-738
69. Okazaki N, Yoshino M, Yoshida T, et al. Evaluation of the prognosis for small hepatocellular carcinoma based on tumor volume doubling time. A preliminary report. Cancer 1989; 63:2207-2210
70. Ebara M, Ohio M, Shinagawa T, et al. Natural history of minute hepatocellular carcinoma smaller than three centimeters complicating cirrhosis. A study in 22 patients. Gastroenterology 1986;90:289-298
71. Barbara L, Benzi G, Gaiani S, et al. Natural history of small untreated hepatocellular carcinoma in cirrhosis: a multivariate analysis of prognostic factors of tumor growth rate and patient survival. Hepatology 1992;16:132-137
72. Okuda H, Obata H, Motoike Y, Hisamitsu T. Clinicopathological features of hepatocellular carcinoma - comparison of hepatitis B seropositive and seronegative patients. Hepatogastroenterology 1984;31:64-68
73. Shijo H, Okazaki M, Kogaemaru F, Higashi M, Sakagushi S, Okumura M. Influence of hepatitis B virus infection and age on mode of growth of hepatocellular carcinoma. Cancer 1991;67: 2626-2632
74. Ikeda K, Saitoh S, Tsubota A, et al. Risk factors for tumor recurrence and prognosis after curative resection of hepatocellular carcinoma. Cancer 1993;71:19-25
75. Llovet JM, Bustamante J, Castells A, et al. Natural history of untreated non-surgical hepatocellular carcinoma: rationale for the design and evaluation of therapeutic trials. Hepatology 1999;29:62-67.
76. Livraghi T, Bolondi L, Buscarini L, et al. No treatment, resection and ethanol injection in hepatocellular carcinoma: a retrospective analysis of survival in 391 patients with cirrhosis. J Hepatol 1995;22:522-526
77. McMahon BJ, London T. Workshop on screening tor hepatocellular carcinoma. J Natl Cancer Inst 1991;83:916-919
78. Colombo M. Early diagnosis of hepatocellular carcinoma in Italy. A summary of a Consensus Development Conference held in Milan, 16 November 1990 by the Italian Association for the Study of the Liver (AISF). J Hepatol 1992;14:401-403
79. Oka H, Kurioka N, Kim K, et al. Prospective study of early detection of hepatocellular carcinoma in patients with cirrhosis. Hepatology 1990;12:680-687
80. Cottone M, Turri M, Caltagirone M, et al. Screening for hepatocellular carcinoma in patients with Child's A cirrhosis: An 8 year prospective study by ultrasound and alpha-fetoprotein. J Hepatol 1994;21:1029-1034
81. Mele A, Marzolini A, Tosti ME, Ciccozzi M, Stroffolini T. SEIEVA Sistema epidemiologico integrato dell'epatite virale acuta. Rapporto 1995-1996. Istituto Superiore di Sanità. Rapporti ISTISAN 97/36
82. Jacobson LP, Zhang BC, Shu YR, et al. Oltipraz chemoprevention trial in Qidong. People's Republic of China: study design and clinical outcomes. Cancer Epidemiol Biomarkers Prev 1997;6:257-265
83. Muto Y, Moriwaki H, Ninomiya M, et al. Prevention of second primary tumors by an acyclic retinoid, polyprenoic acid, in patients with hepatocellular carcinoma. N Engl J Med 1996;334: 1561-1567