Liver-specific cytochrome P450 CYP2C22 is a direct target of retinoic acid and a retinoic acid-metabolizing enzyme in rat liver

Journal of Lipid Research

Volumn 51, Issue 7, 2010, Pages 1781-1792

  Qian, Linxi ^a   Zolfaghari, Reza ^a   Ross, A Catharine ^a  

^a PENNSYLVANIA STATE UNIVERSITY   (United States)

Author keywords

HepG2 cell; Human hepatocyte; In situ hybridization; Polyunsaturated fatty acid; Retinoic acid oxidation; Retinoic acid response element

Indexed keywords

4 [(5,6,7,8 TETRAHYDRO 5,5,8,8 TETRAMETHYL 2 NAPHTHYL)CARBOXAMIDO]BENZOIC ACID; COMPLEMENTARY DNA; CYTOCHROME P450 2C; CYTOCHROME P450 2C22; CYTOCHROME P450 2C8; CYTOCHROME P450 2C9; DRUG METABOLIZING ENZYME; LUCIFERASE; MESSENGER RNA; POLYUNSATURATED FATTY ACID; RETINOIC ACID; RETINOIC ACID RECEPTOR; RETINOID; RETINOID X RECEPTOR; UNCLASSIFIED DRUG; CYP2C8 PROTEIN, HUMAN; CYP2C9 PROTEIN, HUMAN; CYTOCHROME P-450 2C22, RAT; CYTOCHROME P-450 CYP2C SUBFAMILY; CYTOCHROME P450; ISOENZYME; UNSPECIFIC MONOOXYGENASE;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL TISSUE; ARTICLE; CATALYSIS; CELL STRAIN HEK293; CELL STRAIN HEPG2; CONTROLLED STUDY; DNA RESPONSIVE ELEMENT; DRUG METABOLISM; GEL MOBILITY SHIFT ASSAY; GENETIC TRANSFECTION; HEPATOMA CELL; HOMEOSTASIS; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IN SITU HYBRIDIZATION; LIVER CELL; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PLASMID; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN METABOLISM; RAT; REAL TIME POLYMERASE CHAIN REACTION; RNA ISOLATION; UPREGULATION; AMINO ACID SEQUENCE; ANIMAL; CELL LINE; CYTOLOGY; ENZYMOLOGY; GENETICS; LIVER; METABOLISM; MOLECULAR GENETICS; REGULATORY SEQUENCE; SEQUENCE ALIGNMENT;

AMINO ACID SEQUENCE; ANIMALS; ARYL HYDROCARBON HYDROXYLASES; CELL LINE; CYTOCHROME P-450 CYP2C8; CYTOCHROME P-450 CYP2C9; CYTOCHROME P-450 ENZYME SYSTEM; HUMANS; ISOENZYMES; LIVER; MOLECULAR SEQUENCE DATA; RATS; REGULATORY SEQUENCES, NUCLEIC ACID; SEQUENCE ALIGNMENT; TRETINOIN;

EID: 77953498527     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M002840     Document Type: Article

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