The oxidizing enzyme CYP26A1 tightly regulates the availability of retinoic acid in the gastrulating mouse embryo to ensure proper head development and vasculogenesis

Developmental Dynamics

Volumn 236, Issue 3, 2007, Pages 644-653

  Ribes, Vanessa ^a,b,c,d,f   Fraulob, Valérie ^a,b,c,d   Petkovich, Martin ^e   Dollé, Pascal ^a,b,c,d,e  

^a INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^b INSERM   (France)

^c CNRS   (France)

^d UNIVERSITÉ DE STRASBOURG   (France)

^e QUEEN S UNIVERSITY   (Canada)

^f NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

Author keywords

CYP26A1; CYP26B1; Endothelium; Epiblast; Forebrain; Head development; Retinoids; Vascular Development; Yolk sac

Indexed keywords

CYTOCHROME P450; CYTOCHROME P450 26A1; CYTOCHROME P450 26B1; RETINOIC ACID; RETINOID; UNCLASSIFIED DRUG;

ANGIOGENESIS; ANIMAL EXPERIMENT; ARTICLE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DIET SUPPLEMENTATION; EMBRYO; EMBRYO DEVELOPMENT; ENZYME ACTIVITY; FOREBRAIN; GASTRULATION; HEAD; MOUSE; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; OXIDATION; PRIORITY JOURNAL; SINGLE DRUG DOSE; TERATOGENICITY; VASCULAR ENDOTHELIUM; YOLK SAC;

ALLANTOIS; ANIMALS; BODY PATTERNING; CELL DIFFERENTIATION; CYTOCHROME P-450 ENZYME SYSTEM; EMBRYONIC DEVELOPMENT; GASTRULA; MICE; MICE, MUTANT STRAINS; OXIDATION-REDUCTION; PROSENCEPHALON; RHOMBENCEPHALON; TRETINOIN;

VERTEBRATA;

EID: 33947402252     PISSN: 10588388     EISSN: 10970177     Source Type: Journal    
DOI: 10.1002/dvdy.21057     Document Type: Article

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