Tyrosyl-DNA phosphodiesterase 1 targeting for modulation of camptothecin-based treatment

Current Medicinal Chemistry

Volumn 17, Issue 15, 2010, Pages 1500-1508

  Beretta, G L ^a   Cossa, G ^a   Gatti, L ^a   Zunino, F ^a   Perego, P ^a  

^a NATIONAL CANCER INSTITUTE   (Italy)

Author keywords

Camptothecin; DNA repair pathways; Drug resistance; SCAN 1; Topoisomerase 1; Tyrosyl DNA phosphodiesterase 1

Indexed keywords

CAMPTOTHECIN; DEPHOSTATIN; DIMINAZENE ACETURATE; DOUBLE STRANDED DNA; FURAMIDINE; LIVIDOMYCIN; METHYL 3,4 DEPHOSPHATIN; METHYL 3,4 DEPHOSTATIN; METHYLDEPHOSTATIN; NEOMYCIN; NF 449; PAROMOMYCIN; PENTAMIDINE; PHOSPHODIESTERASE I; PHOSPHODIESTERASE INHIBITOR; SURAMIN; TYROSYL DEOXYRIBONUCLEIC ACID PHOSPHODIESTERASE 1; TYROSYL DEOXYRIBONUCLEIC ACID PHOSPHODIESTERASE 1 INHIBITOR; UNCLASSIFIED DRUG; VANADIC ACID;

ARTICLE; DNA REPAIR; DRUG INHIBITION; DRUG STRUCTURE; ENZYME ACTIVITY; ENZYME MECHANISM; GENE MUTATION; NERVE DEGENERATION; NEUROLOGIC DISEASE; NUCLEOTIDE SEQUENCE; PROTEIN FUNCTION;

ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CAMPTOTHECIN; DNA DAMAGE; DNA REPAIR; DNA TOPOISOMERASES, TYPE I; HUMANS; NERVOUS SYSTEM DISEASES; PHOSPHODIESTERASE INHIBITORS; PHOSPHORIC DIESTER HYDROLASES;

EID: 77953489820     PISSN: 09298673     EISSN: None     Source Type: Journal    
DOI: 10.2174/092986710790979971     Document Type: Article

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