Proprotein convertase inhibitory activities of flavonoids isolated from oroxylum Indicum

Current Medicinal Chemistry

Volumn 17, Issue 19, 2010, Pages 2049-2058

  Majumdar, S ^a,b   Mohanta, B C ^b   Chowdhury, D R ^b   Banik, R ^b   Dinda, B ^b   Basak, A ^a,c  

^a OTTAWA HOSPITAL RESEARCH INSTITUTE   (Canada)

^b TRIPURA UNIVERSITY   (India)

^c UNIVERSITY OF OTTAWA   (Canada)

Author keywords

Flavones; Pro insulin growth factor 1 processing; Proprotein convertases; Protease inhibitors

Indexed keywords

BAICALEIN; CHRYSIN; COUMARIN DERIVATIVE; FURIN; OROXYLIN A; OROXYLIN A GLUCOSIDE; PEPTIDE DERIVATIVE; PLANT EXTRACT; PROINSULIN GROWTH FACTOR 1; PROPROTEIN CONVERTASE 4; PROPROTEIN CONVERTASE 5; PROPROTEIN CONVERTASE 7; PROTEIN PRECURSOR; SERINE PROTEINASE; SERINE PROTEINASE INHIBITOR; SOMATOMEDIN C; TERT BUTYLOXYCARBONYL ARGINYLVALYLARGINYLARGINYL 4 METHYLCOUMARIN 7 AMIDE; UNCLASSIFIED DRUG; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; ANTINEOPLASTIC AGENT; FLAVONOID; PRO-INSULIN-LIKE GROWTH FACTOR I; PROTEINASE INHIBITOR; RECOMBINANT PROTEIN;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BARK; CONTROLLED STUDY; DRUG ISOLATION; DRUG MECHANISM; DRUG SCREENING; DRUG SELECTIVITY; ENZYME INHIBITION; IC 50; MEDICINAL PLANT; NONHUMAN; OROXYLUM INDICUM; STRUCTURE ACTIVITY RELATION; ANTAGONISTS AND INHIBITORS; BIGNONIACEAE; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; HUMAN; ISOLATION AND PURIFICATION; METABOLISM;

ANTI-HIV AGENTS; ANTINEOPLASTIC AGENTS; BIGNONIACEAE; FLAVONOIDS; FURIN; HUMANS; INSULIN-LIKE GROWTH FACTOR I; MODELS, MOLECULAR; PROPROTEIN CONVERTASES; PROTEASE INHIBITORS; PROTEIN PRECURSORS; RECOMBINANT PROTEINS;

EID: 77953487306     PISSN: 09298673     EISSN: None     Source Type: Journal    
DOI: 10.2174/092986710791233643     Document Type: Article

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