Erasure of cellular memory by fusion with pluripotent cells

Stem Cells

Volumn 25, Issue 4, 2007, Pages 1013-1020

  Do, Jeong Tae ^a   Dong, Wook Han ^a,b   Gentile, Luca ^a   Sobek Klocke, Ingeborg ^a   Stehling, Martin ^a   Hoon, Taek Lee ^b   Schöler, Hans R ^a  

^a MAX PLANCK INSTITUTE FOR MOLECULAR BIOMEDICINE   (Germany)

^b Konkuk University   (South Korea)

Author keywords

Differentiation; F9 EC cells; Fusion; Oct4; Reprogramming; Xist

Indexed keywords

RETINOIC ACID;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; DOWN REGULATION; GENE INACTIVATION; HYBRID CELL; MARKER GENE; METHYLATION; MOUSE; NONHUMAN; PLURIPOTENT STEM CELL; TISSUE SPECIFICITY; UPREGULATION; X CHROMOSOME;

EID: 34147132369     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1634/stemcells.2006-0691     Document Type: Article

References (33)

1. Do JT, Schöler HR. Cell-cell fusion as a means to establish pluripotency. Ernst Schering Res Found Workshop 2006;35-45.
2. Do JT, Schöler HR. Nuclei of embryonic stem cells reprogram somatic cells. STEM CELLS 2004;22:941-949.
3. Do JT, Schöler HR. Comparison of neurosphere cells with cumulus cells after fusion with embryonic stem cells: reprogramming potential. Reprod Fertil Dev 2005;17:143-149.
4. Flasza M, Shering AF, Smith K et al. Reprogramming in inter-species embryonal carcinoma-somatic cell hybrids induces expression of pluripotency and differentiation markers. Cloning Stem Cells 2003;5:339-354.
5. Hatano SY, Tada M, Kimura H et al. Pluripotential competence of cells associated with Nanog activity. Mech Dev 2005;122:67-79.
6. Tada M, Tada T, Lefebvre L et al. Embryonic germ cells induce epigenetic reprogramming of somatic nucleus in hybrid cells. EMBO J 1997;16:6510-6520.
7. Tada M, Takahama Y, Abe K et al. Nuclear reprogramming of somatic cells by in vitro hybridization with ES cells. Curr Biol 2001;11:1553-1558.
8. Matveeva NM, Shilov AG, Kaftanovskaya EM et al. In vitro and in vivo study of pluripotency in intraspecific hybrid cells obtained by fusion of murine embryonic stem cells with splenocytes. Mol Reprod Dev 1998;50:128-138.
9. Koopman P, Cotton RG. Pluripotent differentiation of single F9 embryonal carcinoma cells. Exp Cell Res 1987;168:567-571.
10. Lehtonen E, Laasonen A, Tienari J. Teratocarcinoma stem cells as a model for differentiation in the mouse embryo. Int J Dev Biol 1989;33:105-115.
11. Nayernia K, Li M, Jaroszynski L et al. Stem cell based therapeutical approach of male infertility by teratocarcinoma derived germ cells. Hum Mol Genet 2004;13:1451-1460.
12. Rochette-Egly C, Chambon P. F9 embryocarcinoma cells: A cell autonomous model to study the functional selectivity of RARs and RXRs in retinoid signaling. Histol Histopathol 2001;16:909-922.
13. Berstine EG, Hooper ML, Grandchamp S et al. Alkaline phosphatase activity in mouse teratoma. Proc Natl Acad Sci U S A 1973;70:3899-3903.
14. Harris TM, Childs G. Global gene expression patterns during differentiation of F9 embryonal carcinoma cells into parietal endoderm. Funct Integr Genomics 2002;2:105-119.
15. Boiani M, Gentile L, Gambles VV et al. Variable reprogramming of the pluripotent stem cell marker Oct4 in mouse clones: Distinct developmental potentials in different culture environments. STEM CELLS 2005;23:1089-1104.
16. Suzuki T, Higgins PJ, Crawford DR. Control selection for RNA quantitation. Biotechniques 2000;29:332-337.
17. Lee JT, Lu N. Targeted mutagenesis of Tsix leads to nonrandom X inactivation. Cell 1999;99:47-57.
18. Panning B, Dausman J, Jaenisch R. X chromosome inactivation is mediated by Xist RNA stabilization. Cell 1997;90:907-916.
19. Beard C, Li E, Jaenisch R. Loss of methylation activates Xist in somatic but not in embryonic cells. Genes Dev 1995;9:2325-2334.
20. Norris DP, Patel D, Kay GF et al. Evidence that random and imprinted Xist expression is controlled by preemptive methylation. Cell 1994;77:41-51.
21. McDonald LE, Paterson CA, Kay GF. Bisulfite genomic sequencingderived methylation profile of the xist gene throughout early mouse development. Genomics 1998;54:379-386.
22. Zuccotti M, Monk M. Methylation of the mouse Xist gene in sperm and eggs correlates with imprinted Xist expression and paternal X-inactivation. Nat Genet 1995;9:316-320.
23. Reddi AH. Bone morphogenetic proteins: an unconventional approach to isolation of first mammalian morphogens. Cytokine Growth Factor Rev 1997;8:11-20.
24. Gitelman I. Twist protein in mouse embryogenesis. Dev Biol 1997;189:205-214.
25. Yang J, Mani SA, Weinberg RA. Exploring a new twist on tumor metastasis. Cancer Res 2006;66:4549-4552.
26. Plageman TF Jr, Yutzey KE. T-box genes and heart development: Putting the "T" in heart. Dev Dyn 2005;232:11-20.
27. Liesi P, Rechardt L, Wartiovaara J. Nerve growth factor induces adrenergic neuronal differentiation in F9 teratocarcinoma cells. Nature 1983;306:265-267.
28. Tienari J, Virtanen I, Soinila S et al. Neuron-like derivatives of cultured F9 embryonal carcinoma cells express characteristics of parietal endoderm cells. Dev Biol 1987;123:566-573.
29. Jones-Villeneuve EM, McBurney MW, Rogers KA et al. Retinoic acid induces embryonal carcinoma cells to differentiate into neurons and glial cells. J Cell Biol 1982;94:253-262.
30. Rougeulle C, Chaumeil J, Sarma K et al. Differential histone H3 Lys-9 and Lys-27 methylation profiles on the X chromosome. Mol Cell Biol 2004;24:5475-5484.
31. Kimura H, Tada M, Hatano S et al. Chromatin reprogramming of male somatic cell-derived XIST and TSIX in ES hybrid cells. Cytogenet Genome Res 2002;99:106-114.
32. Sheardown SA, Duthie SM, Johnston CM et al. Stabilization of Xist RNA mediates initiation of X chromosome inactivation. Cell 1997;91:99-107.
33. Niwa H, Miyazaki J, Smith AG. Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells. Nat Genet 2000;24:372-376.