-
1
-
-
0038024615
-
The G-Protein-Coupled Receptors in the Human Genome Form Five Main Families. Phylogenetic Analysis, Paralogon Groups, and Fingerprints
-
10.1124/mol.63.6.1256, 12761335
-
Fredriksson R, Lagerstrom MC, Lundin L-G, Schioth HB. The G-Protein-Coupled Receptors in the Human Genome Form Five Main Families. Phylogenetic Analysis, Paralogon Groups, and Fingerprints. Molecular Pharmacology 2003, 63(6):1256-1272. 10.1124/mol.63.6.1256, 12761335.
-
(2003)
Molecular Pharmacology
, vol.63
, Issue.6
, pp. 1256-1272
-
-
Fredriksson, R.1
Lagerstrom, M.C.2
Lundin, L.-.G.3
Schioth, H.B.4
-
2
-
-
33748671369
-
The 7 TM G-Protein-Coupled Receptor Target Family
-
Jacoby E, Bouhelal R, Gerspacher M, Seuwen K. The 7 TM G-Protein-Coupled Receptor Target Family. Chem Med Chem 2006, 1(8):760-782.
-
(2006)
Chem Med Chem
, vol.1
, Issue.8
, pp. 760-782
-
-
Jacoby, E.1
Bouhelal, R.2
Gerspacher, M.3
Seuwen, K.4
-
3
-
-
56749103466
-
The 2.6 Angstrom Crystal Structure of a Human A2A Adenosine Receptor Bound to an Antagonist
-
Jaakola V-P, Griffith MT, Hanson MA, Cherezov V, Chien EYT, Lane JR, IJzerman AP, Stevens RC. The 2.6 Angstrom Crystal Structure of a Human A2A Adenosine Receptor Bound to an Antagonist. Science 2008, 1164772.
-
(2008)
Science
, pp. 1164772
-
-
Jaakola, V.-.P.1
Griffith, M.T.2
Hanson, M.A.3
Cherezov, V.4
Chien, E.Y.T.5
Lane, J.R.6
IJzerman, A.P.7
Stevens, R.C.8
-
4
-
-
0034801665
-
G protein-coupled receptor drug discovery: Implications from the crystal structure of rhodopsin
-
Ballesteros J, Palczewski K. G protein-coupled receptor drug discovery: Implications from the crystal structure of rhodopsin. Curr Opin Drug Discovery Dev 2001, 4(5):561-574.
-
(2001)
Curr Opin Drug Discovery Dev
, vol.4
, Issue.5
, pp. 561-574
-
-
Ballesteros, J.1
Palczewski, K.2
-
5
-
-
36448995359
-
High-Resolution Crystal Structure of an Engineered Human β2-Adrenergic G Protein Coupled Receptor
-
10.1126/science.1150577, 2583103, 17962520
-
Cherezov V, Rosenbaum DM, Hanson MA, Rasmussen SGF, Thian FS, Kobilka TS, Choi H-J, Kuhn P, Weis WI, Kobilka BK, et al. High-Resolution Crystal Structure of an Engineered Human β2-Adrenergic G Protein Coupled Receptor. Science 2007, 318(5854):1258-1265. 10.1126/science.1150577, 2583103, 17962520.
-
(2007)
Science
, vol.318
, Issue.5854
, pp. 1258-1265
-
-
Cherezov, V.1
Rosenbaum, D.M.2
Hanson, M.A.3
Rasmussen, S.G.F.4
Thian, F.S.5
Kobilka, T.S.6
Choi, H.-.J.7
Kuhn, P.8
Weis, W.I.9
Kobilka, B.K.10
-
6
-
-
47949129742
-
Structure of a β1-adrenergic G-protein-coupled receptor
-
10.1038/nature07101, 18594507
-
Warne T, Serrano-Vega MJ, Baker JG, Moukhametzianov R, Edwards PC, Henderson R, Leslie AGW, Tate CG, Schertler GFX. Structure of a β1-adrenergic G-protein-coupled receptor. Nature 2008, 454(7203):486-491. 10.1038/nature07101, 18594507.
-
(2008)
Nature
, vol.454
, Issue.7203
, pp. 486-491
-
-
Warne, T.1
Serrano-Vega, M.J.2
Baker, J.G.3
Moukhametzianov, R.4
Edwards, P.C.5
Henderson, R.6
Leslie, A.G.W.7
Tate, C.G.8
Schertler, G.F.X.9
-
7
-
-
0037020329
-
Drug Design Strategies for Targeting G-Protein-Coupled Receptors
-
Klabunde T, Hessler G. Drug Design Strategies for Targeting G-Protein-Coupled Receptors. Chem Bio Chem 2002, 3(10):928-944.
-
(2002)
Chem Bio Chem
, vol.3
, Issue.10
, pp. 928-944
-
-
Klabunde, T.1
Hessler, G.2
-
8
-
-
0036827077
-
Property-Based Design of GPCR-Targeted Library
-
Balakin KV, Tkachenko SE, Lang SA, Okun I, Ivashchenko AA, Savchuk NP. Property-Based Design of GPCR-Targeted Library. J Chem Inf Comput Sci 2002, 42(6):1332-1342.
-
(2002)
J Chem Inf Comput Sci
, vol.42
, Issue.6
, pp. 1332-1342
-
-
Balakin, K.V.1
Tkachenko, S.E.2
Lang, S.A.3
Okun, I.4
Ivashchenko, A.A.5
Savchuk, N.P.6
-
9
-
-
10644241871
-
2,4,6-Trisubstituted Pyrimidines as a New Class of Selective Adenosine A1 Receptor Antagonists
-
10.1021/jm049448r, 15588088
-
Chang LCW, Spanjersberg RF, von Frijtag Drabbe-Künzel JK, Mulder-Krieger T, van den Hout G, Beukers MW, Brussee J, IJzerman AP. 2,4,6-Trisubstituted Pyrimidines as a New Class of Selective Adenosine A1 Receptor Antagonists. J Med Chem 2004, 47(26):6529-6540. 10.1021/jm049448r, 15588088.
-
(2004)
J Med Chem
, vol.47
, Issue.26
, pp. 6529-6540
-
-
Chang, L.C.W.1
Spanjersberg, R.F.2
von Frijtag Drabbe-Künzel, J.K.3
Mulder-Krieger, T.4
van den Hout, G.5
Beukers, M.W.6
Brussee, J.7
IJzerman, A.P.8
-
10
-
-
77954427556
-
Privileged Structures in GPCRs
-
Springer-Verlag, Bourne H, Horuk R, Kuhnke J, Michel H
-
Bywater R. Privileged Structures in GPCRs. GPCRs: From Deorphanization to Lead Structure Identification 2007, 75-92. Springer-Verlag, Bourne H, Horuk R, Kuhnke J, Michel H.
-
(2007)
GPCRs: From Deorphanization to Lead Structure Identification
, pp. 75-92
-
-
Bywater, R.1
-
11
-
-
77950286345
-
Chemogenomics: Looking at biology through the lens of chemistry
-
Doddareddy MR, Westen G, Horst E, Peironcely JE, Corthals F, IJzerman AP, Emmerich M, Jenkins JL, Bender A. Chemogenomics: Looking at biology through the lens of chemistry. Statistical Analysis and Data Mining 2009, 2(3):149-160.
-
(2009)
Statistical Analysis and Data Mining
, vol.2
, Issue.3
, pp. 149-160
-
-
Doddareddy, M.R.1
Westen, G.2
Horst, E.3
Peironcely, J.E.4
Corthals, F.5
IJzerman, A.P.6
Emmerich, M.7
Jenkins, J.L.8
Bender, A.9
-
12
-
-
36048992504
-
Chemogenomic data analysis: Prediction of small-molecule targets and the advent of biological fingerprints
-
Bender A, Young DW, Jenkins JL, Serrano M, Mikhailov D, Clemons PA, Davies JW. Chemogenomic data analysis: Prediction of small-molecule targets and the advent of biological fingerprints. Comb Chem High Throughput Screening 2007, 10(8):719-731.
-
(2007)
Comb Chem High Throughput Screening
, vol.10
, Issue.8
, pp. 719-731
-
-
Bender, A.1
Young, D.W.2
Jenkins, J.L.3
Serrano, M.4
Mikhailov, D.5
Clemons, P.A.6
Davies, J.W.7
-
13
-
-
34548319109
-
Chemogenomic approaches to drug discovery: similar receptors bind similar ligands
-
10.1038/sj.bjp.0707308, 1978276, 17533415
-
Klabunde T. Chemogenomic approaches to drug discovery: similar receptors bind similar ligands. Br J Pharmacol 2007, 152(1):5-7. 10.1038/sj.bjp.0707308, 1978276, 17533415.
-
(2007)
Br J Pharmacol
, vol.152
, Issue.1
, pp. 5-7
-
-
Klabunde, T.1
-
14
-
-
0028338534
-
GCRDb: a G-protein-coupled receptor database
-
Kolakowski LFJ. GCRDb: a G-protein-coupled receptor database. Recept Channels 1994, 2:1-7.
-
(1994)
Recept Channels
, vol.2
, pp. 1-7
-
-
Kolakowski, L.F.J.1
-
15
-
-
30144441512
-
A chemogenomic analysis of the transmembrane binding cavity of human G-protein-coupled receptors
-
Surgand J-S, Rodrigo J, Kellenberger E, Rognan D. A chemogenomic analysis of the transmembrane binding cavity of human G-protein-coupled receptors. Proteins: Struct, Funct, Bioinf 2006, 62(2):509-538.
-
(2006)
Proteins: Struct, Funct, Bioinf
, vol.62
, Issue.2
, pp. 509-538
-
-
Surgand, J.-.S.1
Rodrigo, J.2
Kellenberger, E.3
Rognan, D.4
-
16
-
-
36248970132
-
Crystal structure of the human β2 adrenergic G-protein-coupled receptor
-
10.1038/nature06325, 17952055
-
Rasmussen SGF, Choi H-J, Rosenbaum DM, Kobilka TS, Thian FS, Edwards PC, Burghammer M, Ratnala VRP, Sanishvili R, Fischetti RF, et al. Crystal structure of the human β2 adrenergic G-protein-coupled receptor. Nature 2007, 450(7168):383-387. 10.1038/nature06325, 17952055.
-
(2007)
Nature
, vol.450
, Issue.7168
, pp. 383-387
-
-
Rasmussen, S.G.F.1
Choi, H.-.J.2
Rosenbaum, D.M.3
Kobilka, T.S.4
Thian, F.S.5
Edwards, P.C.6
Burghammer, M.7
Ratnala, V.R.P.8
Sanishvili, R.9
Fischetti, R.F.10
-
17
-
-
67650753759
-
Definition of the G Protein-Coupled Receptor Transmembrane Bundle Binding Pocket and Calculation of Receptor Similarities for Drug Design
-
10.1021/jm900319e, 19537715
-
Gloriam DE, Foord SM, Blaney FE, Garland SL. Definition of the G Protein-Coupled Receptor Transmembrane Bundle Binding Pocket and Calculation of Receptor Similarities for Drug Design. J Med Chem 2009, 52(14):4429-4442. 10.1021/jm900319e, 19537715.
-
(2009)
J Med Chem
, vol.52
, Issue.14
, pp. 4429-4442
-
-
Gloriam, D.E.1
Foord, S.M.2
Blaney, F.E.3
Garland, S.L.4
-
18
-
-
33750986884
-
"Bayes Affinity Fingerprints" Improve Retrieval Rates in Virtual Screening and Define Orthogonal Bioactivity Space: When Are Multitarget Drugs a Feasible Concept?
-
10.1021/ci600197y, 17125186
-
Bender A, Jenkins JL, Glick M, Deng Z, Nettles JH, Davies JW. "Bayes Affinity Fingerprints" Improve Retrieval Rates in Virtual Screening and Define Orthogonal Bioactivity Space: When Are Multitarget Drugs a Feasible Concept?. J Chem Inf Model 2006, 46(6):2445-2456. 10.1021/ci600197y, 17125186.
-
(2006)
J Chem Inf Model
, vol.46
, Issue.6
, pp. 2445-2456
-
-
Bender, A.1
Jenkins, J.L.2
Glick, M.3
Deng, Z.4
Nettles, J.H.5
Davies, J.W.6
-
19
-
-
40049100210
-
Analysis of Pharmacology Data and the Prediction of Adverse Drug Reactions and Off-Target Effects from Chemical Structure
-
10.1002/cmdc.200700026, 17477341
-
Bender A, Scheiber J, Glick M, Davies JW, Azzaoui K, Hamon J, Urban L, Whitebread S, Jenkins JL. Analysis of Pharmacology Data and the Prediction of Adverse Drug Reactions and Off-Target Effects from Chemical Structure. ChemMedChem 2007, 2(6):861-873. 10.1002/cmdc.200700026, 17477341.
-
(2007)
ChemMedChem
, vol.2
, Issue.6
, pp. 861-873
-
-
Bender, A.1
Scheiber, J.2
Glick, M.3
Davies, J.W.4
Azzaoui, K.5
Hamon, J.6
Urban, L.7
Whitebread, S.8
Jenkins, J.L.9
-
20
-
-
33846876695
-
Relating protein pharmacology by ligand chemistry
-
Keiser MJ, Roth BL, Armbruster BN, Ernsberger P, Irwin JJ, Shoichet BK. Relating protein pharmacology by ligand chemistry. Nat Biotech 2007, 25(2):197-206.
-
(2007)
Nat Biotech
, vol.25
, Issue.2
, pp. 197-206
-
-
Keiser, M.J.1
Roth, B.L.2
Armbruster, B.N.3
Ernsberger, P.4
Irwin, J.J.5
Shoichet, B.K.6
-
21
-
-
65249169368
-
Substructure Mining of GPCR Ligands Reveals Activity-Class Specific Functional Groups in an Unbiased Manner
-
10.1021/ci8003896, 19434836
-
van der Horst E, Okuno Y, Bender A, IJzerman AP. Substructure Mining of GPCR Ligands Reveals Activity-Class Specific Functional Groups in an Unbiased Manner. J Chem Inf Model 2009, 49(2):348-360. 10.1021/ci8003896, 19434836.
-
(2009)
J Chem Inf Model
, vol.49
, Issue.2
, pp. 348-360
-
-
van der Horst, E.1
Okuno, Y.2
Bender, A.3
IJzerman, A.P.4
-
24
-
-
22944457221
-
International Union of Pharmacology. XLVI. G Protein-Coupled Receptor List
-
10.1124/pr.57.2.5, 15914470
-
Foord SM, Bonner TI, Neubig RR, Rosser EM, Pin J-P, Davenport AP, Spedding M, Harmar AJ. International Union of Pharmacology. XLVI. G Protein-Coupled Receptor List. Pharmacol Rev 2005, 57(2):279-288. 10.1124/pr.57.2.5, 15914470.
-
(2005)
Pharmacol Rev
, vol.57
, Issue.2
, pp. 279-288
-
-
Foord, S.M.1
Bonner, T.I.2
Neubig, R.R.3
Rosser, E.M.4
Pin, J.-.P.5
Davenport, A.P.6
Spedding, M.7
Harmar, A.J.8
-
25
-
-
0037252680
-
GPCRDB information system for G protein-coupled receptors
-
10.1093/nar/gkg103, 165550, 12520006
-
Horn F, Bettler E, Oliveira L, Campagne F, Cohen FE, Vriend G. GPCRDB information system for G protein-coupled receptors. Nucl Acids Res 2003, 31(1):294-297. 10.1093/nar/gkg103, 165550, 12520006.
-
(2003)
Nucl Acids Res
, vol.31
, Issue.1
, pp. 294-297
-
-
Horn, F.1
Bettler, E.2
Oliveira, L.3
Campagne, F.4
Cohen, F.E.5
Vriend, G.6
-
26
-
-
14644421602
-
The selectivity of β-adrenoceptor antagonists at the human β1, β2 and β3 adrenoceptors
-
10.1038/sj.bjp.0706048, 1576008, 15655528
-
Baker JG. The selectivity of β-adrenoceptor antagonists at the human β1, β2 and β3 adrenoceptors. Br J Pharmacol 2005, 144(3):317-322. 10.1038/sj.bjp.0706048, 1576008, 15655528.
-
(2005)
Br J Pharmacol
, vol.144
, Issue.3
, pp. 317-322
-
-
Baker, J.G.1
-
27
-
-
0028914060
-
Muscarinic receptors and drugs in cardiovascular medicine
-
10.1007/BF00877757, 7786837
-
Van Zwieten PA, Doods HN. Muscarinic receptors and drugs in cardiovascular medicine. Cardiovascular Drugs and Therapy 1995, 9(1):159-167. 10.1007/BF00877757, 7786837.
-
(1995)
Cardiovascular Drugs and Therapy
, vol.9
, Issue.1
, pp. 159-167
-
-
Van Zwieten, P.A.1
Doods, H.N.2
-
28
-
-
0038237079
-
Allosteric site on muscarinic acetylcholine receptors: identification of two amino acids in the muscarinic M2 receptor that account entirely for the M2/M5 subtype selectivities of some structurally diverse allosteric ligands in N-methylscopolamine-occupied receptors
-
10.1124/mol.64.1.21, 12815157
-
Voigtländer U, Jöhren K, Mohr M, Raasch A, Tränkle C, Buller S, Ellis J, Höltje H-D, Mohr K. Allosteric site on muscarinic acetylcholine receptors: identification of two amino acids in the muscarinic M2 receptor that account entirely for the M2/M5 subtype selectivities of some structurally diverse allosteric ligands in N-methylscopolamine-occupied receptors. Molecular Pharmacology 2003, 64(1):21-31. 10.1124/mol.64.1.21, 12815157.
-
(2003)
Molecular Pharmacology
, vol.64
, Issue.1
, pp. 21-31
-
-
Voigtländer, U.1
Jöhren, K.2
Mohr, M.3
Raasch, A.4
Tränkle, C.5
Buller, S.6
Ellis, J.7
Höltje, H.-.D.8
Mohr, K.9
-
29
-
-
38549164272
-
GLIDA: GPCR ligand database for chemical genomics drug discovery database and tools update
-
2238933, 17986454
-
Okuno Y, Tamon A, Yabuuchi H, Niijima S, Minowa Y, Tonomura K, Kunimoto R, Feng C. GLIDA: GPCR ligand database for chemical genomics drug discovery database and tools update. Nucl Acids Res 2008, 36(suppl_1):D907-912. 2238933, 17986454.
-
(2008)
Nucl Acids Res
, vol.36
, Issue.SUPPL 1
-
-
Okuno, Y.1
Tamon, A.2
Yabuuchi, H.3
Niijima, S.4
Minowa, Y.5
Tonomura, K.6
Kunimoto, R.7
Feng, C.8
-
30
-
-
33746156959
-
Global mapping of pharmacological space
-
Paolini GV, Shapland RHB, van Hoorn WP, Mason JS, Hopkins AL. Global mapping of pharmacological space. Nat Biotech 2006, 24(7):805-815.
-
(2006)
Nat Biotech
, vol.24
, Issue.7
, pp. 805-815
-
-
Paolini, G.V.1
Shapland, R.H.B.2
van Hoorn, W.P.3
Mason, J.S.4
Hopkins, A.L.5
-
31
-
-
33847354629
-
Towards a New Generation of Potential Antipsychotic Agents Combining D2 and 5-HT1A Receptor Activities
-
10.1021/jm061180b, 17300168
-
Cuisiat S, Bourdiol N, Lacharme V, Newman-Tancredi A, Colpaert F, Vacher B. Towards a New Generation of Potential Antipsychotic Agents Combining D2 and 5-HT1A Receptor Activities. J Med Chem 2007, 50(4):865-876. 10.1021/jm061180b, 17300168.
-
(2007)
J Med Chem
, vol.50
, Issue.4
, pp. 865-876
-
-
Cuisiat, S.1
Bourdiol, N.2
Lacharme, V.3
Newman-Tancredi, A.4
Colpaert, F.5
Vacher, B.6
-
32
-
-
34248572635
-
Optimisation of anti-psychotic therapeutics: a balancing act?
-
10.1038/sj.bjp.0707164, 2013954, 17375084
-
Lawrence AJ. Optimisation of anti-psychotic therapeutics: a balancing act?. Br J Pharmacol 2007, 151(2):161-162. 10.1038/sj.bjp.0707164, 2013954, 17375084.
-
(2007)
Br J Pharmacol
, vol.151
, Issue.2
, pp. 161-162
-
-
Lawrence, A.J.1
-
33
-
-
0842304428
-
Recognition of Privileged Structures by G-Protein Coupled Receptors
-
10.1021/jm0309452, 14761190
-
Bondensgaard K, Ankersen M, Thogersen H, Hansen BS, Wulff BS, Bywater RP. Recognition of Privileged Structures by G-Protein Coupled Receptors. J Med Chem 2004, 47(4):888-899. 10.1021/jm0309452, 14761190.
-
(2004)
J Med Chem
, vol.47
, Issue.4
, pp. 888-899
-
-
Bondensgaard, K.1
Ankersen, M.2
Thogersen, H.3
Hansen, B.S.4
Wulff, B.S.5
Bywater, R.P.6
-
34
-
-
33645422011
-
Are Target-Family-Privileged Substructures Truly Privileged?
-
10.1021/jm0502900, 16539387
-
Schnur DM, Hermsmeier MA, Tebben AJ. Are Target-Family-Privileged Substructures Truly Privileged?. J Med Chem 2006, 49(6):2000-2009. 10.1021/jm0502900, 16539387.
-
(2006)
J Med Chem
, vol.49
, Issue.6
, pp. 2000-2009
-
-
Schnur, D.M.1
Hermsmeier, M.A.2
Tebben, A.J.3
-
35
-
-
0033971515
-
The utilization of recombinant prostanoid receptors to determine the affinities and selectivities of prostaglandins and related analogs
-
Abramovitz M, Adam M, Boie Y, Carrière M-C, Denis D, Godbout C, Lamontagne S, Rochette C, Sawyer N, Tremblay NM, et al. The utilization of recombinant prostanoid receptors to determine the affinities and selectivities of prostaglandins and related analogs. Biochim Biophys Acta, Mol Cell Biol Lipids 2000, 1483(2):285-293.
-
(2000)
Biochim Biophys Acta, Mol Cell Biol Lipids
, vol.1483
, Issue.2
, pp. 285-293
-
-
Abramovitz, M.1
Adam, M.2
Boie, Y.3
Carrière, M.-.C.4
Denis, D.5
Godbout, C.6
Lamontagne, S.7
Rochette, C.8
Sawyer, N.9
Tremblay, N.M.10
-
36
-
-
33947726053
-
Antagonism of the prostaglandin D2 receptors DP1 and CRTH2 as an approach to treat allergic diseases
-
10.1038/nrd2266, 17396136
-
Pettipher R, Hansel TT, Armer R. Antagonism of the prostaglandin D2 receptors DP1 and CRTH2 as an approach to treat allergic diseases. Nat Rev Drug Discov 2007, 6(4):313-325. 10.1038/nrd2266, 17396136.
-
(2007)
Nat Rev Drug Discov
, vol.6
, Issue.4
, pp. 313-325
-
-
Pettipher, R.1
Hansel, T.T.2
Armer, R.3
-
37
-
-
0034731421
-
A Novel Hepatointestinal Leukotriene B4 Receptor. Cloning and Functional Characterization
-
10.1074/jbc.M004512200, 11006272
-
Wang S, Gustafson E, Pang L, Qiao X, Behan J, Maguire M, Bayne M, Laz T. A Novel Hepatointestinal Leukotriene B4 Receptor. Cloning and Functional Characterization. J Biol Chem 2000, 275(52):40686-40694. 10.1074/jbc.M004512200, 11006272.
-
(2000)
J Biol Chem
, vol.275
, Issue.52
, pp. 40686-40694
-
-
Wang, S.1
Gustafson, E.2
Pang, L.3
Qiao, X.4
Behan, J.5
Maguire, M.6
Bayne, M.7
Laz, T.8
-
38
-
-
0030976460
-
A G-protein-coupled receptor for leukotriene B4 that mediates chemotaxis
-
10.1038/42506, 9177352
-
Yokomizo T, Izumi T, Chang K, Takuwa Y, Shimizu T. A G-protein-coupled receptor for leukotriene B4 that mediates chemotaxis. Nature 1997, 387(6633):620-624. 10.1038/42506, 9177352.
-
(1997)
Nature
, vol.387
, Issue.6633
, pp. 620-624
-
-
Yokomizo, T.1
Izumi, T.2
Chang, K.3
Takuwa, Y.4
Shimizu, T.5
-
39
-
-
0037266558
-
Dopamine receptors for every species: Gene duplications and functional diversification in Craniates
-
10.1023/A:1022686622752, 12836695
-
Le Crom S, Kapsimali M, Barôme P-O, Vernier P. Dopamine receptors for every species: Gene duplications and functional diversification in Craniates. Journal of Structural and Functional Genomics 2003, 3(1):161-176. 10.1023/A:1022686622752, 12836695.
-
(2003)
Journal of Structural and Functional Genomics
, vol.3
, Issue.1
, pp. 161-176
-
-
Le Crom, S.1
Kapsimali, M.2
Barôme, P.-.O.3
Vernier, P.4
-
40
-
-
62249211062
-
Dopamine D1 receptor ligands: where are we now and where are we going
-
10.1002/med.20130, 18642350
-
Zhang J, Xiong B, Zhen X, Zhang A. Dopamine D1 receptor ligands: where are we now and where are we going. Med Res Rev 2009, 29(2):272-294. 10.1002/med.20130, 18642350.
-
(2009)
Med Res Rev
, vol.29
, Issue.2
, pp. 272-294
-
-
Zhang, J.1
Xiong, B.2
Zhen, X.3
Zhang, A.4
-
41
-
-
0042029747
-
Atypical antipsychotic drug actions: unitary or multiple mechanisms for 'atypicality'?
-
Roth BL, Sheffler D, Potkin SG. Atypical antipsychotic drug actions: unitary or multiple mechanisms for 'atypicality'?. Clinical Neuroscience Research 2003, 3(1-2):108-117.
-
(2003)
Clinical Neuroscience Research
, vol.3
, Issue.1-2
, pp. 108-117
-
-
Roth, B.L.1
Sheffler, D.2
Potkin, S.G.3
-
43
-
-
0036037576
-
Convergent Evolution on the Molecular Level
-
10.1159/000063562, 12207082
-
Zakon HH. Convergent Evolution on the Molecular Level. Brain, Behavior and Evolution 2002, 59(5-6):250-261. 10.1159/000063562, 12207082.
-
(2002)
Brain, Behavior and Evolution
, vol.59
, Issue.5-6
, pp. 250-261
-
-
Zakon, H.H.1
-
44
-
-
51349085387
-
Data completeness--the Achilles heel of drug-target networks
-
Mestres J, Gregori-Puigjane E, Valverde S, Sole RV. Data completeness--the Achilles heel of drug-target networks. Nat Biotech 2008, 26(9):983-984.
-
(2008)
Nat Biotech
, vol.26
, Issue.9
, pp. 983-984
-
-
Mestres, J.1
Gregori-Puigjane, E.2
Valverde, S.3
Sole, R.V.4
-
45
-
-
0029894013
-
The Properties of Known Drugs. 1. Molecular Frameworks
-
10.1021/jm9602928, 8709122
-
Bemis GW, Murcko MA. The Properties of Known Drugs. 1. Molecular Frameworks. J Med Chem 1996, 39(15):2887-2893. 10.1021/jm9602928, 8709122.
-
(1996)
J Med Chem
, vol.39
, Issue.15
, pp. 2887-2893
-
-
Bemis, G.W.1
Murcko, M.A.2
-
46
-
-
65249092242
-
Computational Approaches to Fragment and Substructure Discovery and Evaluation
-
West Sussex, U.K.: John Wiley & Sons, Ltd, Zartler ER, Shapiro J, Chichester M
-
van der Horst E, IJzerman AP. Computational Approaches to Fragment and Substructure Discovery and Evaluation. Fragment-Based Drug Discovery: A Practical Approach 2008, West Sussex, U.K.: John Wiley & Sons, Ltd, Zartler ER, Shapiro J, Chichester M.
-
(2008)
Fragment-Based Drug Discovery: A Practical Approach
-
-
van der Horst, E.1
IJzerman, A.P.2
-
47
-
-
35148868252
-
A Chemogenomic Analysis of the Human Proteome: Application to Enzyme Families
-
10.1177/1087057107306759, 17942790
-
Bernasconi P, Min C, Galasinski S, Popa-Burke I, Bobasheva A, Coudurier L, Birkos S, Hallam R, Janzen WP. A Chemogenomic Analysis of the Human Proteome: Application to Enzyme Families. J Biomol Screen 2007, 12(7):972-982. 10.1177/1087057107306759, 17942790.
-
(2007)
J Biomol Screen
, vol.12
, Issue.7
, pp. 972-982
-
-
Bernasconi, P.1
Min, C.2
Galasinski, S.3
Popa-Burke, I.4
Bobasheva, A.5
Coudurier, L.6
Birkos, S.7
Hallam, R.8
Janzen, W.P.9
-
48
-
-
84888281419
-
ChEMBL
-
ChEMBL. , http://www.ebi.ac.uk/chembl/
-
-
-
-
49
-
-
2542477991
-
Screening the receptorome to discover the molecular targets for plant-derived psychoactive compounds: a novel approach for CNS drug discovery
-
10.1016/j.pharmthera.2004.03.004, 15163592
-
Roth BL, Lopez E, Beischel S, Westkaemper RB, Evans JM. Screening the receptorome to discover the molecular targets for plant-derived psychoactive compounds: a novel approach for CNS drug discovery. Pharmacol Ther 2004, 102(2):99-110. 10.1016/j.pharmthera.2004.03.004, 15163592.
-
(2004)
Pharmacol Ther
, vol.102
, Issue.2
, pp. 99-110
-
-
Roth, B.L.1
Lopez, E.2
Beischel, S.3
Westkaemper, R.B.4
Evans, J.M.5
-
50
-
-
38549097071
-
The Universal Protein Resource (UniProt)
-
2238893, 18045787, The UniProt Consortium
-
The UniProt Consortium The Universal Protein Resource (UniProt). Nucl Acids Res 2008, 36(suppl_1):D190-195. 2238893, 18045787, The UniProt Consortium.
-
(2008)
Nucl Acids Res
, vol.36
, Issue.SUPPL 1
-
-
-
51
-
-
38549092091
-
Database resources of the National Center for Biotechnology Information
-
2238880, 18045790
-
Wheeler DL, Barrett T, Benson DA, Bryant SH, Canese K, Chetvernin V, Church DM, DiCuccio M, Edgar R, Federhen S, et al. Database resources of the National Center for Biotechnology Information. Nucl Acids Res 2008, (36 Database):D13-D21. 2238880, 18045790.
-
(2008)
Nucl Acids Res
, Issue.36
-
-
Wheeler, D.L.1
Barrett, T.2
Benson, D.A.3
Bryant, S.H.4
Canese, K.5
Chetvernin, V.6
Church, D.M.7
DiCuccio, M.8
Edgar, R.9
Federhen, S.10
-
52
-
-
33644876210
-
DrugBank: a comprehensive resource for in silico drug discovery and exploration
-
10.1093/nar/gkj067, 1347430, 16381955
-
Wishart DS, Knox C, Guo AC, Shrivastava S, Hassanali M, Stothard P, Chang Z, Woolsey J. DrugBank: a comprehensive resource for in silico drug discovery and exploration. Nucl Acids Res 2006, 34(suppl_1):D668-672. 10.1093/nar/gkj067, 1347430, 16381955.
-
(2006)
Nucl Acids Res
, vol.34
, Issue.SUPPL 1
-
-
Wishart, D.S.1
Knox, C.2
Guo, A.C.3
Shrivastava, S.4
Hassanali, M.5
Stothard, P.6
Chang, Z.7
Woolsey, J.8
-
53
-
-
84888277019
-
GPCRDB
-
GPCRDB. , http://www.gpcr.org/7tm/
-
-
-
-
54
-
-
84888276599
-
GASTON
-
GASTON. , http://www.liacs.nl/~snijssen/gaston/
-
-
-
-
55
-
-
33646435063
-
A Quantitative Comparison of the Subgraph Miners MoFa, gSpan, FFSM, and Gaston
-
Wörlein M, Meinl T, Fischer I, Philippsen M. A Quantitative Comparison of the Subgraph Miners MoFa, gSpan, FFSM, and Gaston. Knowledge Discovery in Databases: PKDD 2005 2005, 392-403.
-
(2005)
Knowledge Discovery in Databases: PKDD 2005
, pp. 392-403
-
-
Wörlein, M.1
Meinl, T.2
Fischer, I.3
Philippsen, M.4
-
57
-
-
0003437302
-
PHYLIP (Phylogeny Inference Package) version 3.6. Distributed by the author. Department of Genome Sciences, University of Washington, Seattle
-
Felsenstein J. PHYLIP (Phylogeny Inference Package) version 3.6. Distributed by the author. Department of Genome Sciences, University of Washington, Seattle. 2005,
-
(2005)
-
-
Felsenstein, J.1
-
58
-
-
34547781750
-
MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) Software Version 4.0
-
10.1093/molbev/msm092, 17488738
-
Tamura K, Dudley J, Nei M, Kumar S. MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) Software Version 4.0. Mol Biol Evol 2007, 24(8):1596-1599. 10.1093/molbev/msm092, 17488738.
-
(2007)
Mol Biol Evol
, vol.24
, Issue.8
, pp. 1596-1599
-
-
Tamura, K.1
Dudley, J.2
Nei, M.3
Kumar, S.4
-
59
-
-
0001334659
-
Solution Phase Synthesis of Chemical Libraries for Lead Discovery
-
Garr CD, Peterson JR, Schultz L, Oliver AR, Underiner TL, Cramer RD, Ferguson AM, Lawless MS, Patterson DE. Solution Phase Synthesis of Chemical Libraries for Lead Discovery. J Biomol Screen 1996, 1(4):179-186.
-
(1996)
J Biomol Screen
, vol.1
, Issue.4
, pp. 179-186
-
-
Garr, C.D.1
Peterson, J.R.2
Schultz, L.3
Oliver, A.R.4
Underiner, T.L.5
Cramer, R.D.6
Ferguson, A.M.7
Lawless, M.S.8
Patterson, D.E.9
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