Resveratrol mobilizes endogenous copper in human peripheral lymphocytes leading to oxidative DNA breakage: A putative mechanism for chemoprevention of cancer

Pharmaceutical Research

Volumn 27, Issue 6, 2010, Pages 979-988

  Hadi, S M ^a   Ullah, M F ^a   Azmi, A S ^b   Ahmad, A ^b   Shamim, U ^a   Zubair, H ^a   Khan, H Y ^a  

^a ALIGARH MUSLIM UNIVERSITY   (India)

^b WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cancer; Comet assay; Endogenous copper; Pro oxidant action; Resveratrol

Indexed keywords

COPPER; POLYPHENOL; RESVERATROL;

ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; CANCER INHIBITION; CANCER PREVENTION; CARCINOGENESIS; COPPER BLOOD LEVEL; COPPER METABOLISM; COPPER MOBILIZATION; CYTOTOXICITY; DNA DEGRADATION; DNA STRAND BREAKAGE; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; IN VITRO STUDY; MALIGNANT NEOPLASTIC DISEASE; OXIDATIVE STRESS; PERIPHERAL LYMPHOCYTE; PRIORITY JOURNAL; REVIEW;

ANTICARCINOGENIC AGENTS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CHEMOPREVENTION; COPPER; DNA DAMAGE; HUMANS; LYMPHOCYTES; NEOPLASMS; STILBENES;

EID: 77953230291     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-010-0055-4     Document Type: Review

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