Plant polyphenols mobilize nuclear copper in human peripheral lymphocytes leading to oxidatively generated DNA breakage: Implications for an anticancer mechanism

Free Radical Research

Volumn 42, Issue 8, 2008, Pages 764-772

  Shamim, Uzma ^a   Hanif, Sarmad ^a   Ullah, M F ^a   Azmi, Asfar ^b   Bhat, Showket ^c   Hadi, S M ^a  

^a ALIGARH MUSLIM UNIVERSITY   (India)

^b WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Comet assay; Nuclear copper; Plant polyphenols; Pro oxidant DNA breakage

Indexed keywords

2,9 DIMETHYL 1,10 PHENANTHROLINE; CAFFEIC ACID; COPPER; DAIDZEIN; DELPHINIDIN; DNA; EPIGALLOCATECHIN GALLATE; GALLIC ACID; PLANT EXTRACT; POLYPHENOL; REACTIVE OXYGEN METABOLITE; RESVERATROL; SCAVENGER; TANNIN;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL ISOLATION; CELL MEMBRANE PERMEABILITY; CELL NUCLEUS; CELL NUCLEUS MEMBRANE; COMET ASSAY; CONTROLLED STUDY; DNA DEGRADATION; DNA STRAND BREAKAGE; DNA SYNTHESIS INHIBITION; HUMAN; HUMAN CELL; INCUBATION TIME; NORMAL HUMAN; OXIDATIVE STRESS; PERIPHERAL LYMPHOCYTE;

ANTINEOPLASTIC AGENTS; CATECHIN; CELL NUCLEUS; CELL SURVIVAL; CELLS, CULTURED; COMET ASSAY; DNA BREAKS; FLAVONOIDS; HUMANS; HYDROGEN PEROXIDE; LYMPHOCYTES; OXIDANTS; OXIDATION-REDUCTION; OXIDATIVE STRESS; PHENANTHROLINES; PHENOLS; PLANT EXTRACTS;

EID: 50849110132     PISSN: 10715762     EISSN: 10292470     Source Type: Journal    
DOI: 10.1080/10715760802302251     Document Type: Article

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