Human retinal pigment epithelium-induced CD4+CD25+ regulatory T cells suppress activation of intraocular effector T cells

Clinical Immunology

Volumn 136, Issue 1, 2010, Pages 83-95

  Horie, Shintaro ^a   Sugita, Sunao ^a   Futagami, Yuri ^a   Yamada, Yukiko ^a   Mochizuki, Manabu ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

Eye; Immune privilege; Regulatory T cells; Retinal pigment epithelium; TGF

Indexed keywords

CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; GAMMA INTERFERON; INTERLEUKIN 10; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1;

ARTICLE; CD4+ CD25+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; EFFECTOR CELL; HUMAN; HUMAN CELL; IMMUNOLOGICAL TOLERANCE; IMMUNOREGULATION; PIGMENT EPITHELIUM; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; UVEITIS;

ANTIBODIES, MONOCLONAL; CD4-POSITIVE T-LYMPHOCYTES; CELL LINE; CELL PROLIFERATION; CULTURE MEDIA, CONDITIONED; DINOPROSTONE; EPITHELIAL CELLS; EYE; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION; HUMANS; IMMUNE TOLERANCE; INTERFERON-GAMMA; INTERLEUKIN-10; INTERLEUKIN-2 RECEPTOR ALPHA SUBUNIT; LYMPHOCYTE ACTIVATION; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; RETINAL PIGMENT EPITHELIUM; RNA, SMALL INTERFERING; T-LYMPHOCYTES; T-LYMPHOCYTES, REGULATORY; TH1 CELLS; THROMBOSPONDIN 1; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA2; UVEITIS;

EID: 77953021264     PISSN: 15216616     EISSN: 15217035     Source Type: Journal    
DOI: 10.1016/j.clim.2010.03.001     Document Type: Article

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