Deoxynivalenol affects in vitro intestinal epithelial cell barrier integrity through inhibition of protein synthesis

Toxicology and Applied Pharmacology

Volumn 245, Issue 3, 2010, Pages 291-298

  De Walle, Jacqueline Van ^a   Sergent, Thérèse ^a   Piront, Neil ^b   Toussaint, Olivier ^b   Schneider, Yves Jacques ^a   Larondelle, Yvan ^a  

^a UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^b UNIVERSITY OF NAMUR   (Belgium)

Author keywords

Barrier permeability; Caco 2 cells; Deoxynivalenol; Intestinal epithelium; Protein synthesis; Tight junction

Indexed keywords

ALKALINE PHOSPHATASE; CLAUDIN 4; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LEUCINE; MANNITOL; MITOGEN ACTIVATED PROTEIN KINASE; MYCOTOXIN; OCCLUDIN; STRESS ACTIVATED PROTEIN KINASE; TRITIUM; VOMITOXIN;

ARTICLE; CELL DIFFERENTIATION; CELL MEMBRANE PERMEABILITY; CELL STRAIN CACO 2; CELL TRANSPORT; CEREAL; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ELECTRIC RESISTANCE; FOOD CONTAMINATION; FOOD PROCESSING; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; IN VITRO STUDY; INTESTINE EPITHELIUM CELL; MONOLAYER CULTURE; PERMEABILITY BARRIER; PROTEIN CONTENT; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN SYNTHESIS INHIBITION; TIGHT JUNCTION; TOXIN ANALYSIS; WESTERN BLOTTING;

ALKALINE PHOSPHATASE; CACO-2 CELLS; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; ELECTRIC IMPEDANCE; FOOD CONTAMINATION; HUMANS; INTESTINAL ABSORPTION; INTESTINAL MUCOSA; MANNITOL; MEMBRANE PROTEINS; PERMEABILITY; PROTEIN BIOSYNTHESIS; PROTEIN SYNTHESIS INHIBITORS; RNA, MESSENGER; TIGHT JUNCTIONS; TIME FACTORS; TRICHOTHECENES;

EID: 77952953521     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2010.03.012     Document Type: Article

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