The food contaminant deoxynivalenol, decreases intestinal barrier permeability and reduces claudin expression

Toxicology and Applied Pharmacology

Volumn 237, Issue 1, 2009, Pages 41-48

  Pinton, Philippe ^a   Nougayrède, Jean Philippe ^b   Del Rio, Juan Carlos ^a   Moreno, Carolina ^a   Marin, Daniela E ^a,c   Ferrier, Laurent ^d   Bracarense, Ana Paula ^e   Kolf Clauw, Martine ^f   Oswald, Isabelle P ^a  

^a CEMAGREF   (France)

^b IHAP   (France)

^c Institutul National de Cercetare Dezvoltare pentru Biologie si Nutritie Animala Bucharest   (Romania)

^d UMR1054   (France)

^e STATE UNIVERSITY OF LONDRINA   (Brazil)

^f UNIVERSITÉ DE TOULOUSE   (France)

Author keywords

Barrier function; Deoxynivalenol; Intestinal permeability; Mycotoxin; Proteins; Tight junction

Indexed keywords

CLAUDIN; DEXTRAN; MYCOTOXIN; VOMITOXIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL FOOD; ANIMAL TISSUE; ARTICLE; CELL STRAIN CACO 2; CEREAL; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOTOXICITY TEST; DOSE TIME EFFECT RELATION; ELECTRIC RESISTANCE; ESCHERICHIA COLI; EX VIVO STUDY; EXPLANT; FOOD CONTAMINATION; HEALTH HAZARD; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOFLUORESCENCE MICROSCOPY; IN VITRO STUDY; IN VIVO STUDY; INTESTINE EPITHELIUM CELL; INTESTINE MUCOSA PERMEABILITY; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; SWINE; TIGHT JUNCTION;

ANIMALS; CACO-2 CELLS; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRIC IMPEDANCE; FOOD CONTAMINATION; HUMANS; INTESTINAL ABSORPTION; INTESTINAL MUCOSA; MEMBRANE POTENTIALS; MEMBRANE PROTEINS; MYCOTOXINS; PERMEABILITY; PROTEIN ISOFORMS; STATISTICS, NONPARAMETRIC; SWINE; TIGHT JUNCTIONS; TRICHOTHECENES;

ANIMALIA; ESCHERICHIA COLI; SUIDAE; SUS;

EID: 67349256779     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2009.03.003     Document Type: Article

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