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Volumn 52, Issue 5, 2010, Pages 433-455

Transforming growth factor β2 is negatively regulated by endogenous retinoic acid during early heart morphogenesis

Author keywords

Cardiovascular morphogenesis; Quail embryo; Transforming growth factor 2; Vitamin A

Indexed keywords

MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; RAF PROTEIN; RETINOIC ACID; SMAD1 PROTEIN; SMAD5 PROTEIN; SMAD8 PROTEIN; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2; TRANSFORMING GROWTH FACTOR BETA2;

EID: 77952934354     PISSN: 00121592     EISSN: 1440169X     Source Type: Journal    
DOI: 10.1111/j.1440-169X.2010.01183.x     Document Type: Article
Times cited : (9)

References (135)
  • 1
    • 33645409019 scopus 로고    scopus 로고
    • A sweet link between TGFβ and vascular disease?
    • Akhurst, R. J. 2006. A sweet link between TGFβ and vascular disease? Nat. Genet. 38, 400 401.
    • (2006) Nat. Genet. , vol.38 , pp. 400-401
    • Akhurst, R.J.1
  • 2
    • 33745243399 scopus 로고    scopus 로고
    • Transforming growth factor β signaling, vascular remodeling, and hypertension
    • August, P. Suthanthiran, M. 2006. Transforming growth factor β signaling, vascular remodeling, and hypertension. N. Engl. J. Med. 354, 2721 3723.
    • (2006) N. Engl. J. Med. , vol.354 , pp. 2721-3723
    • August, P.1    Suthanthiran, M.2
  • 3
    • 39749130550 scopus 로고    scopus 로고
    • Primary and immortalized mouse epicardial cells undergo differentiation in response to TGFβ
    • Austin, A. F., Compton, L. A., Love, J. D., Brown, C. B. Barnett, J. V. 2008. Primary and immortalized mouse epicardial cells undergo differentiation in response to TGFβ. Dev. Dyn. 237, 366 376.
    • (2008) Dev. Dyn. , vol.237 , pp. 366-376
    • Austin, A.F.1    Compton, L.A.2    Love, J.D.3    Brown, C.B.4    Barnett, J.V.5
  • 5
  • 6
    • 0035810984 scopus 로고    scopus 로고
    • Double-outlet right ventricle and overriding tricuspid valve reflect disturbances of looping, myocardialization, endocardial cushion differentiation and apoptosis in TGFbeta(2)-knockout mice
    • Bartram, U., Molin, D. G., Wisse, L. J., Mohamad, A., Sanford, L. P., Doetschman, T., Speer, C. P., Poelmann, R. E. Gittenberger-de Groot, A. C. 2001. Double-outlet right ventricle and overriding tricuspid valve reflect disturbances of looping, myocardialization, endocardial cushion differentiation and apoptosis in TGFbeta(2)-knockout mice. Circulation 103, 2745 2752.
    • (2001) Circulation , vol.103 , pp. 2745-2752
    • Bartram, U.1    Molin, D.G.2    Wisse, L.J.3    Mohamad, A.4    Sanford, L.P.5    Doetschman, T.6    Speer, C.P.7    Poelmann, R.E.8    Gittenberger-De Groot, A.C.9
  • 7
    • 1542710344 scopus 로고    scopus 로고
    • Nuclear retinoid receptors and the transcription of retinoid target genes
    • Bastien, J. Rochette-Egly, C. 2004. Nuclear retinoid receptors and the transcription of retinoid target genes. Gene 328, 1 16.
    • (2004) Gene , vol.328 , pp. 1-16
    • Bastien, J.1    Rochette-Egly, C.2
  • 8
    • 0033564830 scopus 로고    scopus 로고
    • Differential distribution of retinoic acid synthesis in the chicken embryo as determined by immunolocalization of the retinoic acid synthetic enzyme, RALDH-2
    • Berggren, K., McCaffery, P., Drager, U. Forehand, C. J. 1999. Differential distribution of retinoic acid synthesis in the chicken embryo as determined by immunolocalization of the retinoic acid synthetic enzyme, RALDH-2. Dev. Biol. 210, 288 304.
    • (1999) Dev. Biol. , vol.210 , pp. 288-304
    • Berggren, K.1    McCaffery, P.2    Drager, U.3    Forehand, C.J.4
  • 9
    • 67649211584 scopus 로고    scopus 로고
    • All-trans-retinoic acid represses obesity and insulin resistance by activating both peroxisome proliferation-activated receptor β/δ and retinoic acid receptor
    • Berry, D. C. Noy, N. 2009. All-trans-retinoic acid represses obesity and insulin resistance by activating both peroxisome proliferation-activated receptor β/δ and retinoic acid receptor. Mol. Cell. Biol. 29, 3286 3296.
    • (2009) Mol. Cell. Biol. , vol.29 , pp. 3286-3296
    • Berry, D.C.1    Noy, N.2
  • 10
    • 0030880648 scopus 로고    scopus 로고
    • Retinoids may increase fibrotic potential of TGF-β: Crosstalk between two multifunctional effectors
    • Blomhoff, R. 1997. Retinoids may increase fibrotic potential of TGF-β: crosstalk between two multifunctional effectors. Hepatology 22, 1067 1078.
    • (1997) Hepatology , vol.22 , pp. 1067-1078
    • Blomhoff, R.1
  • 11
    • 33746829275 scopus 로고    scopus 로고
    • Transforming growth factor-βs and vascular disorders
    • Bobik, A. 2006. Transforming growth factor-βs and vascular disorders. Arterioscler. Thromb. Vasc. Biol. 26, 1712 1720.
    • (2006) Arterioscler. Thromb. Vasc. Biol. , vol.26 , pp. 1712-1720
    • Bobik, A.1
  • 12
    • 2642564628 scopus 로고    scopus 로고
    • Signaling hierarchy downstream of retinoic acid that independently regulates vascular remodeling and endothelial cell proliferation
    • Bohnsack, B. L., Lai, L., Dolle, P. Hirschi, K. K. 2004. Signaling hierarchy downstream of retinoic acid that independently regulates vascular remodeling and endothelial cell proliferation. Genes Dev. 18, 1345 1358.
    • (2004) Genes Dev. , vol.18 , pp. 1345-1358
    • Bohnsack, B.L.1    Lai, L.2    Dolle, P.3    Hirschi, K.K.4
  • 13
    • 0032940943 scopus 로고    scopus 로고
    • Antibodies directed against the chicken type II TGFβ receptor identify endothelial cells in the developing chicken and quail
    • Brown, C. B., Drake, C. J. Barnett, J. V. 1999. Antibodies directed against the chicken type II TGFβ receptor identify endothelial cells in the developing chicken and quail. Dev. Dyn. 215, 79 85.
    • (1999) Dev. Dyn. , vol.215 , pp. 79-85
    • Brown, C.B.1    Drake, C.J.2    Barnett, J.V.3
  • 14
    • 18144374535 scopus 로고    scopus 로고
    • Transforming growth factor-β1 signaling participates in the physiological and pathological regulation of mouse inner ear development by all-trans retinoic acid
    • Butts, S. C., Liu, W., Li, G. Frenz, D. A. 2005. Transforming growth factor-β1 signaling participates in the physiological and pathological regulation of mouse inner ear development by all-trans retinoic acid. Birth Defects Res. (PartA). 73, 218 228.
    • (2005) Birth Defects Res. (PartA). , vol.73 , pp. 218-228
    • Butts, S.C.1    Liu, W.2    Li, G.3    Frenz, D.A.4
  • 15
    • 0032908432 scopus 로고    scopus 로고
    • Smad5 knockout mice die at mid-gestation due to multiple embryonic and extraembryonic defects
    • Chang, H., Huylebroeck, D., Verschueren, K., Guo, Q., Matzuk, M. M. Zwijsen, A. 1999. Smad5 knockout mice die at mid-gestation due to multiple embryonic and extraembryonic defects. Development 126, 1631 1642.
    • (1999) Development , vol.126 , pp. 1631-1642
    • Chang, H.1    Huylebroeck, D.2    Verschueren, K.3    Guo, Q.4    Matzuk, M.M.5    Zwijsen, A.6
  • 16
    • 0036904895 scopus 로고    scopus 로고
    • Genetic analysis of the mammalian transforming growth factor-β superfamily
    • Chang, H., Brown, C. W. Matzuk, M. M. 2002. Genetic analysis of the mammalian transforming growth factor-β superfamily. Endocr. Rev. 23, 787 823.
    • (2002) Endocr. Rev. , vol.23 , pp. 787-823
    • Chang, H.1    Brown, C.W.2    Matzuk, M.M.3
  • 17
    • 34548562240 scopus 로고    scopus 로고
    • Inhibition of Tgf β signaling by endogenous retinoic acid is essential for primary lung bud induction
    • Chen, F., Desai, T. J., Qian, J., Niederreither, K., Lu, J. Dardoso, W. V. 2007. Inhibition of Tgf β signaling by endogenous retinoic acid is essential for primary lung bud induction. Development 134, 2969 2979.
    • (2007) Development , vol.134 , pp. 2969-2979
    • Chen, F.1    Desai, T.J.2    Qian, J.3    Niederreither, K.4    Lu, J.5    Dardoso, W.V.6
  • 18
    • 0036029643 scopus 로고    scopus 로고
    • The role of vitamin A in mammalian reproduction and embryonic development
    • Clagett-Dame, M. DeLuca, H. F. 2002. The role of vitamin A in mammalian reproduction and embryonic development. Annu. Rev. Nutr. 22, 347 381.
    • (2002) Annu. Rev. Nutr. , vol.22 , pp. 347-381
    • Clagett-Dame, M.1    Deluca, H.F.2
  • 19
    • 42149159492 scopus 로고    scopus 로고
    • Wnt signaling: An essential regulator of cardiovascular differentiation, morphogenesis and progenitor self-renewal
    • Cohen, E. D., Tian, Y. Morrisey, E. E. 2008. Wnt signaling: an essential regulator of cardiovascular differentiation, morphogenesis and progenitor self-renewal. Development 135, 789 798.
    • (2008) Development , vol.135 , pp. 789-798
    • Cohen, E.D.1    Tian, Y.2    Morrisey, E.E.3
  • 20
    • 33646878085 scopus 로고    scopus 로고
    • Effects of high dose retinoic acid on TGF-β2 expression during pancreatic organogenesis
    • Colakoglu, N., Kukner, A., Oner, J., Sonmez, M. F., Oner, H. Ozan, E. 2006. Effects of high dose retinoic acid on TGF-β2 expression during pancreatic organogenesis. J. Mol. Histol. 36, 413 418.
    • (2006) J. Mol. Histol. , vol.36 , pp. 413-418
    • Colakoglu, N.1    Kukner, A.2    Oner, J.3    Sonmez, M.F.4    Oner, H.5    Ozan, E.6
  • 21
    • 33644975212 scopus 로고    scopus 로고
    • Transforming growth factorβ induces loss of epithelial character and smooth muscle cell differentiation in epicardial cells
    • Compton, L. A., Potash, D. A., Mundell, N. A. Barnett, J. V. 2006. Transforming growth factorβ induces loss of epithelial character and smooth muscle cell differentiation in epicardial cells. Dev. Dyn. 235, 82 93.
    • (2006) Dev. Dyn. , vol.235 , pp. 82-93
    • Compton, L.A.1    Potash, D.A.2    Mundell, N.A.3    Barnett, J.V.4
  • 22
    • 0043166515 scopus 로고    scopus 로고
    • Retinoid receptors and vitamin A deficiency: Differential patterns of transcription during early avian development and the rapid induction of RARs by retinoic acid
    • Cui, J., Michaille, J.-J., Jiang, W. Zile, M. H. 2003. Retinoid receptors and vitamin A deficiency: differential patterns of transcription during early avian development and the rapid induction of RARs by retinoic acid. Dev. Biol. 260, 496 511.
    • (2003) Dev. Biol. , vol.260 , pp. 496-511
    • Cui, J.1    Michaille, J.-J.2    Jiang, W.3    Zile, M.H.4
  • 23
    • 0027137898 scopus 로고
    • Induction of normal cardiovascular development in the vitamin A-deprived quail embryo by natural retinoids
    • Dersch, H. Zile, M. H. 1993. Induction of normal cardiovascular development in the vitamin A-deprived quail embryo by natural retinoids. Dev. Biol. 160, 424 433.
    • (1993) Dev. Biol. , vol.160 , pp. 424-433
    • Dersch, H.1    Zile, M.H.2
  • 24
    • 0142104985 scopus 로고    scopus 로고
    • Smad-dependent and Smad-independent pathways in TGF-β family signaling
    • Derynck, R. Zhang, Y. E. 2003. Smad-dependent and Smad-independent pathways in TGF-β family signaling. Nature 425, 577 584.
    • (2003) Nature , vol.425 , pp. 577-584
    • Derynck, R.1    Zhang, Y.E.2
  • 25
    • 0027413059 scopus 로고
    • RNA and protein localizations of TGFβ2 in the early mouse embryo suggest an involvement in cardiac development
    • Dickson, M. C., Lager, H. G., Duffie, E., Mummery, C. L. Akhurst, R. J. 1993. RNA and protein localizations of TGFβ2 in the early mouse embryo suggest an involvement in cardiac development. Development 117, 625 639.
    • (1993) Development , vol.117 , pp. 625-639
    • Dickson, M.C.1    Lager, H.G.2    Duffie, E.3    Mummery, C.L.4    Akhurst, R.J.5
  • 26
    • 68049118709 scopus 로고    scopus 로고
    • Developmental expression of retinoic acid receptors (RARs)
    • Dolle, P. 2009. Developmental expression of retinoic acid receptors (RARs). Nucl. Recept. Signal. 7, e006.
    • (2009) Nucl. Recept. Signal. , vol.7 , pp. 006
    • Dolle, P.1
  • 27
    • 0029609369 scopus 로고
    • Endogenous retinoids in the early avian embryo
    • Dong, D. Zile, M. H. 1995. Endogenous retinoids in the early avian embryo. Biochem. Biophys. Res. Commun. 217, 1026 1031.
    • (1995) Biochem. Biophys. Res. Commun. , vol.217 , pp. 1026-1031
    • Dong, D.1    Zile, M.H.2
  • 28
    • 51549116267 scopus 로고    scopus 로고
    • Retinoic acid synthesis and signaling during early organogenesis
    • Duester, G. 2008. Retinoic acid synthesis and signaling during early organogenesis. Cell 134, 921 931.
    • (2008) Cell , vol.134 , pp. 921-931
    • Duester, G.1
  • 29
    • 29144486106 scopus 로고    scopus 로고
    • The complex pattern of SMAD signaling in the cardiovascular system
    • Euler-Taimor, G. Heger, J. 2006. The complex pattern of SMAD signaling in the cardiovascular system. Cardiovasc. Res. 69, 15 25.
    • (2006) Cardiovasc. Res. , vol.69 , pp. 15-25
    • Euler-Taimor, G.1    Heger, J.2
  • 30
    • 24044523205 scopus 로고    scopus 로고
    • Regulation of hematopoiesis by retinoid signaling
    • Evans, T. 2005. Regulation of hematopoiesis by retinoid signaling. Exp. Hematol. 33, 1055 1061.
    • (2005) Exp. Hematol. , vol.33 , pp. 1055-1061
    • Evans, T.1
  • 31
    • 23044466047 scopus 로고    scopus 로고
    • Specificity and versatility in TGF-β signaling through Smads
    • Feng, X.-H. Derynk, R. 2005. Specificity and versatility in TGF-β signaling through Smads. Annu. Rev. Cell Dev. Biol. 21, 659 693.
    • (2005) Annu. Rev. Cell Dev. Biol. , vol.21 , pp. 659-693
    • Feng, X.-H.1    Derynk, R.2
  • 32
    • 33748542875 scopus 로고    scopus 로고
    • A critical developmental role for tgfbr2 in myogenic cell lineages revealed in mice expressing SN22- Cre, not SMMHC-Cre
    • Frutkin, A. D., Shi, H., Otuska, G., Leveen, P., Karlsson, S. Dichek, D. A. 2006. A critical developmental role for tgfbr2 in myogenic cell lineages revealed in mice expressing SN22- Cre, not SMMHC-Cre. J. Mol. Cell. Cardiol. 41, 724 731.
    • (2006) J. Mol. Cell. Cardiol. , vol.41 , pp. 724-731
    • Frutkin, A.D.1    Shi, H.2    Otuska, G.3    Leveen, P.4    Karlsson, S.5    Dichek, D.A.6
  • 33
    • 33747017789 scopus 로고    scopus 로고
    • Bmp2 and Gata4 function additively to rescue heart tube development in the absence of retinoids
    • Ghatpande, S., Brand, T., Zile, M. Evans, T. 2006. Bmp2 and Gata4 function additively to rescue heart tube development in the absence of retinoids. Dev. Dyn. 235, 2030 2039.
    • (2006) Dev. Dyn. , vol.235 , pp. 2030-2039
    • Ghatpande, S.1    Brand, T.2    Zile, M.3    Evans, T.4
  • 35
    • 0037007226 scopus 로고    scopus 로고
    • Balancing the activation state of the endothelium via two distinct TGF-β type i receptors
    • Goumans, M.-J., Valdimarsdottir, G., Itoh, S., Rosendahl, A., Sideras, P. ten Dijke, P. 2002. Balancing the activation state of the endothelium via two distinct TGF-β type I receptors. EMBO J. 21, 1743 1753.
    • (2002) EMBO J. , vol.21 , pp. 1743-1753
    • Goumans, M.-J.1    Valdimarsdottir, G.2    Itoh, S.3    Rosendahl, A.4    Sideras, P.5    Ten Dijke, P.6
  • 36
    • 0141428794 scopus 로고    scopus 로고
    • Controlling the angiogenic switch. A balance between two distinct TGF-β receptor signaling pathways
    • Goumans, M.-J., Lebrin, F. Valdimarsdottir, G. 2003. Controlling the angiogenic switch. A balance between two distinct TGF-β receptor signaling pathways. Trends Cardiovasc. Med. 13, 301 307.
    • (2003) Trends Cardiovasc. Med. , vol.13 , pp. 301-307
    • Goumans, M.-J.1    Lebrin, F.2    Valdimarsdottir, G.3
  • 37
    • 0029780320 scopus 로고    scopus 로고
    • RXRα deficiency confers genetic susceptibility for aortic sac, conotruncal, atrioventricular cushion, and ventricular muscle defects in mice
    • Gruber, P. J., Kubalak, S. W., Pexieder, T., Sucov, H. M., Evans, R. M. Chien, K. R. 1996. RXRα deficiency confers genetic susceptibility for aortic sac, conotruncal, atrioventricular cushion, and ventricular muscle defects in mice. J. Clin. Invest. 98, 1332 1343.
    • (1996) J. Clin. Invest. , vol.98 , pp. 1332-1343
    • Gruber, P.J.1    Kubalak, S.W.2    Pexieder, T.3    Sucov, H.M.4    Evans, R.M.5    Chien, K.R.6
  • 38
    • 84924926133 scopus 로고
    • A series of normal stages in the development of the chick embryo
    • Hamburger, V. Hamilton, H. L. 1951. A series of normal stages in the development of the chick embryo. J. Morphol. 88, 49 92.
    • (1951) J. Morphol. , vol.88 , pp. 49-92
    • Hamburger, V.1    Hamilton, H.L.2
  • 39
    • 0030960368 scopus 로고    scopus 로고
    • All-trans-retinoic acid increases transforming growth factor-β2 and insulin-like growth factor binding protein-3 expression trough a retinoic acid receptor-α-dependent signaling pathway
    • Han, G. R., Dohi, D. F., Lee, H. Y., Rajah, R., Walsh, G. L., Hong, W. K., Cohen, P. Kurie, J. M. 1997. All-trans-retinoic acid increases transforming growth factor-β2 and insulin-like growth factor binding protein-3 expression trough a retinoic acid receptor-α-dependent signaling pathway. J. Biol. Chem. 23, 13711 13716.
    • (1997) J. Biol. Chem. , vol.23 , pp. 13711-13716
    • Han, G.R.1    Dohi, D.F.2    Lee, H.Y.3    Rajah, R.4    Walsh, G.L.5    Hong, W.K.6    Cohen, P.7    Kurie, J.M.8
  • 40
    • 33749246730 scopus 로고    scopus 로고
    • Mutations of TGFβ signaling molecules in human disease
    • Harradine, K. A. Akhurst, R. J. 2006. Mutations of TGFβ signaling molecules in human disease. Ann. Med. 38, 403 414.
    • (2006) Ann. Med. , vol.38 , pp. 403-414
    • Harradine, K.A.1    Akhurst, R.J.2
  • 41
    • 0036301401 scopus 로고    scopus 로고
    • Patterning the vertebrate heart
    • Harvey, R. P. 2002. Patterning the vertebrate heart. Nat. Genet. 3, 544 556.
    • (2002) Nat. Genet. , vol.3 , pp. 544-556
    • Harvey, R.P.1
  • 43
    • 0023117283 scopus 로고
    • Spatial and temporal expression pattern of N-cadherin cell adhesion molecules correlated with morphogenetic processes of chicken embryo
    • Hatta, K., Takagi, S., Hajime, F. Takeichi, M. 1987. Spatial and temporal expression pattern of N-cadherin cell adhesion molecules correlated with morphogenetic processes of chicken embryo. Dev. Biol. 120, 215 227.
    • (1987) Dev. Biol. , vol.120 , pp. 215-227
    • Hatta, K.1    Takagi, S.2    Hajime, F.3    Takeichi, M.4
  • 45
    • 0022353776 scopus 로고
    • Effects of retinoid deficiency on the development of the heart and vascular system of the quail embryo
    • Heine, U. I., Roberts, A. B., Munoz, E. F., Roche, N. S. Sporn, M. B. 1985. Effects of retinoid deficiency on the development of the heart and vascular system of the quail embryo. Cell. Pathol. 50, 135 152.
    • (1985) Cell. Pathol. , vol.50 , pp. 135-152
    • Heine, U.I.1    Roberts, A.B.2    Munoz, E.F.3    Roche, N.S.4    Sporn, M.B.5
  • 46
    • 0033555544 scopus 로고    scopus 로고
    • Transcriptional regulation of the Bmp2 gene. Retinoic acid induction in F9 embryonal carcinoma cells and Saccharomyces cerevisiae
    • Heller, L. C., Li, Y., Abrams, K. L. Rogers, M. B. 1999. Transcriptional regulation of the Bmp2 gene. Retinoic acid induction in F9 embryonal carcinoma cells and Saccharomyces cerevisiae. J. Biol. Chem. 274, 1394 1400.
    • (1999) J. Biol. Chem. , vol.274 , pp. 1394-1400
    • Heller, L.C.1    Li, Y.2    Abrams, K.L.3    Rogers, M.B.4
  • 47
    • 0029029002 scopus 로고
    • Incidence of congenital heart disease: Postnatal incidence
    • Hoffman, J. I. E. 1995. Incidence of congenital heart disease: Postnatal incidence. Pediatr. Cardiol. 16, 103 113.
    • (1995) Pediatr. Cardiol. , vol.16 , pp. 103-113
    • Hoffman, J.I.E.1
  • 48
    • 39849085736 scopus 로고    scopus 로고
    • The expanding role for retinoid signaling in heart development
    • Hoover, L. L., Burton, E. G., Brooks, B. A. Kubalak, S. W. 2008. The expanding role for retinoid signaling in heart development. Sci. World J. 8, 194 211.
    • (2008) Sci. World J. , vol.8 , pp. 194-211
    • Hoover, L.L.1    Burton, E.G.2    Brooks, B.A.3    Kubalak, S.W.4
  • 49
    • 0030810959 scopus 로고    scopus 로고
    • 9,13-di-cis-retinoic acid induces the production of tPA and activation of latent TGFβ via RARα in a human liver stellate cell line, LI90
    • Imai, S., Okuno, M., Moriwaki, H., Muto, Y., Murakami, K., Shudo, K., Suzuki, Y. Kojima, S. 1997. 9,13-di-cis-retinoic acid induces the production of tPA and activation of latent TGFβ via RARα in a human liver stellate cell line, LI90. FEBS Lett. 411, 102 106.
    • (1997) FEBS Lett. , vol.411 , pp. 102-106
    • Imai, S.1    Okuno, M.2    Moriwaki, H.3    Muto, Y.4    Murakami, K.5    Shudo, K.6    Suzuki, Y.7    Kojima, S.8
  • 50
    • 33646713486 scopus 로고    scopus 로고
    • The TGFβ activated kinase TAK1 regulates vascular development in vivo
    • Jadrich, J. L., O'Connor, M. B. Coucouvanis, E. 2006. The TGFβ activated kinase TAK1 regulates vascular development in vivo. Development 133, 1529 1541.
    • (2006) Development , vol.133 , pp. 1529-1541
    • Jadrich, J.L.1    O'Connor, M.B.2    Coucouvanis, E.3
  • 51
    • 0027952727 scopus 로고
    • Expression of transforming growth factor-beta2 and beta 3 mRNAs and proteins in the developing chicken embryo
    • Jakowlew, S. B., Ciment, G., Tuan, R. S., Sporn, M. B. Roberts, A. B. 1994. Expression of transforming growth factor-beta2 and beta 3 mRNAs and proteins in the developing chicken embryo. Differentiation 55, 105 118.
    • (1994) Differentiation , vol.55 , pp. 105-118
    • Jakowlew, S.B.1    Ciment, G.2    Tuan, R.S.3    Sporn, M.B.4    Roberts, A.B.5
  • 52
    • 33845878509 scopus 로고    scopus 로고
    • Tgfβ signaling is required for atrioventricular cushion mesenchyme remodeling during in vivo cardiac development
    • Jiao, K., Langworthy, M., Batts, L., Brown, C. B., Moses, H. Baldwin, H. S. 2006. Tgfβ signaling is required for atrioventricular cushion mesenchyme remodeling during in vivo cardiac development. Development 133, 4585 4593.
    • (2006) Development , vol.133 , pp. 4585-4593
    • Jiao, K.1    Langworthy, M.2    Batts, L.3    Brown, C.B.4    Moses, H.5    Baldwin, H.S.6
  • 53
    • 43149095145 scopus 로고    scopus 로고
    • Bone morphogenetic proteins signal through the transforming growth factor -β Type III receptor
    • Kirkbride, K. C., Townsend, T. A., Bruinsma, M. W., Barnett, J. V. Blobe, G. C. 2008. Bone morphogenetic proteins signal through the transforming growth factor -β type III receptor. J. Biol. Chem. 283, 7628 7637.
    • (2008) J. Biol. Chem. , vol.283 , pp. 7628-7637
    • Kirkbride, K.C.1    Townsend, T.A.2    Bruinsma, M.W.3    Barnett, J.V.4    Blobe, G.C.5
  • 55
    • 0342572710 scopus 로고
    • Expression of genes for retinoic acid receptors and TGFβ during quail embryogenesis
    • Kostetskii, I. Zile, M. H. 1993. Expression of genes for retinoic acid receptors and TGFβ during quail embryogenesis. FASEB J. 7, 522A.
    • (1993) FASEB J. , vol.7
    • Kostetskii, I.1    Zile, M.H.2
  • 56
    • 0031686871 scopus 로고    scopus 로고
    • Initial retinoid requirement for early avian development coincides with retinoid receptor coexpression in the precardiac fields and induction of normal cardiovascular development
    • Kostetskii, I., Yuan, S.-Y., Kostetskaia, E., Linask, K. K., Blanchet, S., Seleiro, E., Michaille, J.-J., Brickell, P. Zile, M. 1998. Initial retinoid requirement for early avian development coincides with retinoid receptor coexpression in the precardiac fields and induction of normal cardiovascular development. Dev. Dyn. 213, 188 198.
    • (1998) Dev. Dyn. , vol.213 , pp. 188-198
    • Kostetskii, I.1    Yuan, S.-Y.2    Kostetskaia, E.3    Linask, K.K.4    Blanchet, S.5    Seleiro, E.6    Michaille, J.-J.7    Brickell, P.8    Zile, M.9
  • 57
    • 0033557907 scopus 로고    scopus 로고
    • Retinoid signaling required for normal heart development regulates GATA-4 in a pathway distinct from cardiomyocyte differentiation
    • Kostetskii, I., Jiang, Y., Kostetskaia, E., Yuan, S., Evans, T. Zile, M. 1999. Retinoid signaling required for normal heart development regulates GATA-4 in a pathway distinct from cardiomyocyte differentiation. Dev. Biol. 206, 206 218.
    • (1999) Dev. Biol. , vol.206 , pp. 206-218
    • Kostetskii, I.1    Jiang, Y.2    Kostetskaia, E.3    Yuan, S.4    Evans, T.5    Zile, M.6
  • 58
    • 0036337353 scopus 로고    scopus 로고
    • Elevated transforming growth factor β2 enhances apoptosis and contributes to abnormal outflow tract and aortic sac development in retinoid X receptor α knockout embryos
    • Kubalak, S. W., Hutson, D. R., Scott, K. K. Shannon, R. A. 2002. Elevated transforming growth factor β2 enhances apoptosis and contributes to abnormal outflow tract and aortic sac development in retinoid X receptor α knockout embryos. Development 129, 733 746.
    • (2002) Development , vol.129 , pp. 733-746
    • Kubalak, S.W.1    Hutson, D.R.2    Scott, K.K.3    Shannon, R.A.4
  • 59
    • 0000102555 scopus 로고    scopus 로고
    • Retinoids in heart development
    • ed. R. P. Harvey. Academic Press
    • Kubalak, S. W. Sucov, H. M. 1999. Retinoids in heart development. In : Heart Development (ed R. P. Harvey pp. 209 219. Academic Press
    • (1999) Heart Development , pp. 209-219
    • Kubalak, S.W.1    Sucov, H.M.2
  • 60
    • 24644495693 scopus 로고    scopus 로고
    • The role of Smad signaling in hematopoiesis
    • Larsson, J. Karlsson, S. 2005. The role of Smad signaling in hematopoiesis. Oncogene 24, 5676 5692.
    • (2005) Oncogene , vol.24 , pp. 5676-5692
    • Larsson, J.1    Karlsson, S.2
  • 61
    • 3342908667 scopus 로고    scopus 로고
    • Critical role for retinol in the generation/differentiation of angioblasts required for embryonic blood vessel formation
    • LaRue, A. C., Argraves, W. S., Zile, M. H. Drake, C. J. 2004. Critical role for retinol in the generation/differentiation of angioblasts required for embryonic blood vessel formation. Dev. Dyn. 230, 666 674.
    • (2004) Dev. Dyn. , vol.230 , pp. 666-674
    • Larue, A.C.1    Argraves, W.S.2    Zile, M.H.3    Drake, C.J.4
  • 63
    • 48449086316 scopus 로고    scopus 로고
    • TGFβ - A master of all T cell trades
    • Li, M. L. Flavell, R. A. 2008. TGFβ - A master of all T cell trades. Cell 134, 392 404.
    • (2008) Cell , vol.134 , pp. 392-404
    • Li, M.L.1    Flavell, R.A.2
  • 64
    • 0034634007 scopus 로고    scopus 로고
    • Homocysteine inhibits retinoic acid synthesis: A mechanism for homocysteine-induced congenital defects
    • Limpach, A., Dalton, M., Miles, R. Gadson, P. 2000. Homocysteine inhibits retinoic acid synthesis: a mechanism for homocysteine-induced congenital defects. Exp. Cell. Res. 260, 166 174.
    • (2000) Exp. Cell. Res. , vol.260 , pp. 166-174
    • Limpach, A.1    Dalton, M.2    Miles, R.3    Gadson, P.4
  • 65
    • 0037775851 scopus 로고    scopus 로고
    • Regulation of heart morphology: Current molecular and cellular perspectives on the coordinated emergence of cardiac form and function
    • Linask, K. K. 2003. Regulation of heart morphology: current molecular and cellular perspectives on the coordinated emergence of cardiac form and function. Birth Defects Res. (Part C). 69, 14 24.
    • (2003) Birth Defects Res. (Part C). , vol.69 , pp. 14-24
    • Linask, K.K.1
  • 66
    • 0028088752 scopus 로고
    • Function of the retinoic acid receptors (RARs) during development (I). Craniofacial and skeletal abnormalities in RAR double mutants
    • Lohnes, D., Mark, M., Mendelsohn, C., Dolle, P., Dierich, A., Gorry, P., Gansmuller, A. Chambon, P. 1994. Function of the retinoic acid receptors (RARs) during development (I). Craniofacial and skeletal abnormalities in RAR double mutants. Development 120, 2723 2748.
    • (1994) Development , vol.120 , pp. 2723-2748
    • Lohnes, D.1    Mark, M.2    Mendelsohn, C.3    Dolle, P.4    Dierich, A.5    Gorry, P.6    Gansmuller, A.7    Chambon, P.8
  • 67
    • 0025987832 scopus 로고
    • Structure and expression of the membrane protoeoglycan betaglycan, a component of the TGF-β receptor system
    • Lopez-Casillas, F., Cheifetz, S., Doody, J., Andres, J. L., Lane, W. S. Massague, J. 1991. Structure and expression of the membrane protoeoglycan betaglycan, a component of the TGF-β receptor system. Cell 67, 785 795.
    • (1991) Cell , vol.67 , pp. 785-795
    • Lopez-Casillas, F.1    Cheifetz, S.2    Doody, J.3    Andres, J.L.4    Lane, W.S.5    Massague, J.6
  • 69
    • 77952939984 scopus 로고    scopus 로고
    • New aspects of the control of retinoic acid synthesis in the chick embryo
    • Maden, M. Reijntjes, S. 2009. New aspects of the control of retinoic acid synthesis in the chick embryo. Dev.Biol. 331, 398.
    • (2009) Dev.Biol. , vol.331 , pp. 398
    • Maden, M.1    Reijntjes, S.2
  • 70
    • 0026682845 scopus 로고
    • Interactions between retinoids and TGFβs in mouse morphogenesis
    • Mahmood, R., Flanders, K. C. Morriss-Kay, G. M. 1992. Interactions between retinoids and TGFβs in mouse morphogenesis. Development 115, 67 74.
    • (1992) Development , vol.115 , pp. 67-74
    • Mahmood, R.1    Flanders, K.C.2    Morriss-Kay, G.M.3
  • 71
    • 0029076952 scopus 로고
    • The effects of retinoid status on TGFβ expression during mouse embryogenesis
    • Mahmood, R., Flanders, K. C. Morriss-Kay, G. M. 1995. The effects of retinoid status on TGFβ expression during mouse embryogenesis. Anat. Embryol. 192, 21 33.
    • (1995) Anat. Embryol. , vol.192 , pp. 21-33
    • Mahmood, R.1    Flanders, K.C.2    Morriss-Kay, G.M.3
  • 72
    • 9944253559 scopus 로고    scopus 로고
    • Regulation of proliferation and migration in retinoic acid treated C3H10T1/2cells by TGF-β isoforms
    • Makhijani, N. S., Bischoff, D. S. Yamaguchi, D. T. 2005. Regulation of proliferation and migration in retinoic acid treated C3H10T1/2cells by TGF-β isoforms. J. Cell. Physiol. 202, 304 313.
    • (2005) J. Cell. Physiol. , vol.202 , pp. 304-313
    • Makhijani, N.S.1    Bischoff, D.S.2    Yamaguchi, D.T.3
  • 73
    • 66849101522 scopus 로고    scopus 로고
    • Function of retinoic acid receptors during embryonic development
    • Mark, M., Gyselinck, N. B. Chambon, P. 2009. Function of retinoic acid receptors during embryonic development. Nucl. Recept. Signal. 7, e002.
    • (2009) Nucl. Recept. Signal. , vol.7 , pp. 002
    • Mark, M.1    Gyselinck, N.B.2    Chambon, P.3
  • 74
  • 75
    • 37649026049 scopus 로고    scopus 로고
    • TGFβ2 activation status during cardiac morphogenesis
    • McCormick, K. M. 2001. TGFβ2 activation status during cardiac morphogenesis. Dev. Dyn. 222, 17 25.
    • (2001) Dev. Dyn. , vol.222 , pp. 17-25
    • McCormick, K.M.1
  • 77
    • 34250695906 scopus 로고    scopus 로고
    • Multiple transforming growth factor-β isoforms and receptors function during epithelial-mesenchymal cell transformation in the embryonic heart
    • Mercado-Pimentel, M. E. Runyan, R. B. 2007. Multiple transforming growth factor-β isoforms and receptors function during epithelial-mesenchymal cell transformation in the embryonic heart. Cell Tissues Organs 185, 146 154.
    • (2007) Cell Tissues Organs , vol.185 , pp. 146-154
    • Mercado-Pimentel, M.E.1    Runyan, R.B.2
  • 78
    • 0342844267 scopus 로고    scopus 로고
    • RALDH3, a retinaldehyde dehydrogenase that generates retinoic acid, is expressed in the ventral retina, otic vesicle and olfactory pit during mouse development
    • Mic, F. A., Molotkov, A., Fan, X., Cuenca, A. E. Duester, G. 2000. RALDH3, a retinaldehyde dehydrogenase that generates retinoic acid, is expressed in the ventral retina, otic vesicle and olfactory pit during mouse development. Mech. Dev. 97, 227 230.
    • (2000) Mech. Dev. , vol.97 , pp. 227-230
    • Mic, F.A.1    Molotkov, A.2    Fan, X.3    Cuenca, A.E.4    Duester, G.5
  • 79
    • 0036337341 scopus 로고    scopus 로고
    • Novel retinoic acid generating activities in the neural tube and heart identified by conditional rescue of Raldh2 null mutant mice
    • Mic, F. A., Haselbeck, R. J., Cuenca, A. E. Duester, G. 2002. Novel retinoic acid generating activities in the neural tube and heart identified by conditional rescue of Raldh2 null mutant mice. Development 129, 2271 2282.
    • (2002) Development , vol.129 , pp. 2271-2282
    • Mic, F.A.1    Haselbeck, R.J.2    Cuenca, A.E.3    Duester, G.4
  • 81
    • 33847390216 scopus 로고    scopus 로고
    • Role of retinoic acid during forebrain development begins late when Raldh3 generates retinoic acid in the ventral subventricular zone
    • Molotkova, N., Molotkov, A. Duester, G. 2007. Role of retinoic acid during forebrain development begins late when Raldh3 generates retinoic acid in the ventral subventricular zone. Dev. Biol. 303, 601 610.
    • (2007) Dev. Biol. , vol.303 , pp. 601-610
    • Molotkova, N.1    Molotkov, A.2    Duester, G.3
  • 83
    • 24944497786 scopus 로고    scopus 로고
    • Non-smad TGF-beta signals
    • Moustakas, A. Heldin, C. H. 2005. Non-smad TGF-beta signals. J. Cell Sci. 118, 3573 3584.
    • (2005) J. Cell Sci. , vol.118 , pp. 3573-3584
    • Moustakas, A.1    Heldin, C.H.2
  • 84
    • 0030755115 scopus 로고    scopus 로고
    • N-cadherin is crucial for heart formation in the chick embryo
    • Nakagawa, S. Takeichi, M. 1997. N-cadherin is crucial for heart formation in the chick embryo. Dev. Growth Differ. 39, 451 455.
    • (1997) Dev. Growth Differ. , vol.39 , pp. 451-455
    • Nakagawa, S.1    Takeichi, M.2
  • 85
    • 0000758556 scopus 로고
    • A new technique for the cultivation of the chick embryo in vitro
    • New, D. A. T. 1955. A new technique for the cultivation of the chick embryo in vitro. J. Embryol. Exp. Morphol. 3, 326 331.
    • (1955) J. Embryol. Exp. Morphol. , vol.3 , pp. 326-331
    • New, D.A.T.1
  • 86
    • 60849123968 scopus 로고    scopus 로고
    • TGFβ signals regulate axonal development through distinct Smad-independent mechanisms
    • Ng, J. 2008. TGFβ signals regulate axonal development through distinct Smad-independent mechanisms. Development 135, 4025 4035.
    • (2008) Development , vol.135 , pp. 4025-4035
    • Ng, J.1
  • 87
    • 0035028993 scopus 로고    scopus 로고
    • Embryonic retinoic acid synthesis is essential for heart morphogenesis in the mouse
    • Niederreither, K., Vermot, J., Messaddeq, N., Schuhbaur, B., Chambon, P. Dolle, P. 2001. Embryonic retinoic acid synthesis is essential for heart morphogenesis in the mouse. Development 128, 1019 1031. (Pubitemid 32401419)
    • (2001) Development , vol.128 , Issue.7 , pp. 1019-1031
    • Niederreither, K.1    Vermot, J.2    Messaddeq, N.3    Schuhbaur, B.4    Chambon, P.5    Dolle, P.6
  • 91
    • 33644989417 scopus 로고    scopus 로고
    • Transforming growth factor-β stimulates epithelial-mesenchymal transformations in the proepicardium
    • Olivey, H. E., Mundell, N. A., Austin, A. F. Barnett, J. V. 2006. Transforming growth factor-β stimulates epithelial-mesenchymal transformations in the proepicardium. Dev. Dyn. 235, 50 59.
    • (2006) Dev. Dyn. , vol.235 , pp. 50-59
    • Olivey, H.E.1    Mundell, N.A.2    Austin, A.F.3    Barnett, J.V.4
  • 92
    • 0030579203 scopus 로고    scopus 로고
    • TGF-beta receptor type II deficiency results in defects of yolk sac hematopoiesis and vasculogenesis
    • Oshima, M., Oshima, H. Taketo, M. M. 1996. TGF-beta receptor type II deficiency results in defects of yolk sac hematopoiesis and vasculogenesis. Dev. Biol. 179, 297 302.
    • (1996) Dev. Biol. , vol.179 , pp. 297-302
    • Oshima, M.1    Oshima, H.2    Taketo, M.M.3
  • 93
    • 0026343597 scopus 로고
    • The effects of retinoic acid on heart formation in the early chick embryo
    • Osmond, M. K., Butler, A. J., Voon, F. C. Bellairs, R. 1991. The effects of retinoic acid on heart formation in the early chick embryo. Development 113, 1405 1417.
    • (1991) Development , vol.113 , pp. 1405-1417
    • Osmond, M.K.1    Butler, A.J.2    Voon, F.C.3    Bellairs, R.4
  • 95
    • 0032763469 scopus 로고    scopus 로고
    • Specificity, diversity, and regulation in TGF-β superfamily signaling
    • Piek, E., Heldin, C.-H. Ten Dijke, P. 1999. Specificity, diversity, and regulation in TGF-β superfamily signaling. FASEB J. 13, 2105 2124.
    • (1999) FASEB J. , vol.13 , pp. 2105-2124
    • Piek, E.1    Heldin, C.-H.2    Ten Dijke, P.3
  • 96
    • 0026777853 scopus 로고
    • Mechanistic interrelationships between two superfamilies: The steroid/retinoid receptors and transforming growth factor-β
    • Roberts, A. B. Sporn, M. B. 1992a. Mechanistic interrelationships between two superfamilies: the steroid/retinoid receptors and transforming growth factor-β. Cancer. Surv. 14, 205 220.
    • (1992) Cancer. Surv. , vol.14 , pp. 205-220
    • Roberts, A.B.1    Sporn, M.B.2
  • 97
    • 0026772232 scopus 로고
    • Differential expression of the TGF-β isoforms in embryogenesis suggests specific roles in developing and adult tissues
    • Roberts, A. B. Sporn, M. B. 1992b. Differential expression of the TGF-β isoforms in embryogenesis suggests specific roles in developing and adult tissues. Mol. Repro. Dev. 32, 91 98.
    • (1992) Mol. Repro. Dev. , vol.32 , pp. 91-98
    • Roberts, A.B.1    Sporn, M.B.2
  • 98
    • 68049143179 scopus 로고    scopus 로고
    • Dynamic and combinatorial control of gene expression by nuclelar retinoic acid receptors (RARs)
    • Rochette-Egly, C. Germain, P. 2009. Dynamic and combinatorial control of gene expression by nuclelar retinoic acid receptors (RARs). Nucl. Recept. Signal. 7, e005.
    • (2009) Nucl. Recept. Signal. , vol.7 , pp. 005
    • Rochette-Egly, C.1    Germain, P.2
  • 99
    • 0034235433 scopus 로고    scopus 로고
    • Slug is an essential target of TGFβ2 signaling in the developing chicken heart
    • Romano, L. A. Runyan, R. B. 2000. Slug is an essential target of TGFβ2 signaling in the developing chicken heart. Dev. Biol. 223, 91 102.
    • (2000) Dev. Biol. , vol.223 , pp. 91-102
    • Romano, L.A.1    Runyan, R.B.2
  • 100
    • 0344737840 scopus 로고    scopus 로고
    • Function of RARγ and RARα2 at the initiation of retinoid signaling is essential for avian embryo survival and for distinct events in cardiac morphogenesis
    • Romeih, M., Cui, J., Michaille, J.-J., Jiang, W. Zile, M. H. 2003. Function of RARγ and RARα2 at the initiation of retinoid signaling is essential for avian embryo survival and for distinct events in cardiac morphogenesis. Dev. Dyn. 228, 697 708.
    • (2003) Dev. Dyn. , vol.228 , pp. 697-708
    • Romeih, M.1    Cui, J.2    Michaille, J.-J.3    Jiang, W.4    Zile, M.H.5
  • 101
    • 70849099970 scopus 로고    scopus 로고
    • Retinoic acid is a negative physiological regulator of N-cadherin during early avian heart morphogenesis
    • Romeih, M., Cakstina, I. Zile, M. H. 2009. Retinoic acid is a negative physiological regulator of N-cadherin during early avian heart morphogenesis. Dev. Growth. Differ. 51, 753 767.
    • (2009) Dev. Growth. Differ. , vol.51 , pp. 753-767
    • Romeih, M.1    Cakstina, I.2    Zile, M.H.3
  • 102
    • 0036439461 scopus 로고    scopus 로고
    • Signaling pathways in vascular development
    • Rossant, J. Howard, L. 2002. Signaling pathways in vascular development. Annu. Rev. Cell. Dev. Biol. 18, 541 573.
    • (2002) Annu. Rev. Cell. Dev. Biol. , vol.18 , pp. 541-573
    • Rossant, J.1    Howard, L.2
  • 104
    • 0027521292 scopus 로고
    • Retinoic acid receptors and retinoid X receptor-α down-regulate the transforming growth factor-β1 promoter by antagonizing AP-1 activity
    • Salbert, G., Fanjul, A., Piedrafita, F. J., Lu, X. P., Kim, S. J., Tran, P. Pfahl, M. 1993. Retinoic acid receptors and retinoid X receptor-α down-regulate the transforming growth factor-β1 promoter by antagonizing AP-1 activity. Mol. Endocrinol. 7, 1347 1356.
    • (1993) Mol. Endocrinol. , vol.7 , pp. 1347-1356
    • Salbert, G.1    Fanjul, A.2    Piedrafita, F.J.3    Lu, X.P.4    Kim, S.J.5    Tran, P.6    Pfahl, M.7
  • 106
    • 34249087361 scopus 로고    scopus 로고
    • Opposing effects of retinoic acid on cell growth result from alternate activation of two different nuclear receptors
    • Schug, T. T., Berry, D. C., Shaw, N. S., Travis, S. N. Noy, N. 2007. Opposing effects of retinoic acid on cell growth result from alternate activation of two different nuclear receptors. Cell 129, 723 733.
    • (2007) Cell , vol.129 , pp. 723-733
    • Schug, T.T.1    Berry, D.C.2    Shaw, N.S.3    Travis, S.N.4    Noy, N.5
  • 107
    • 41149137542 scopus 로고    scopus 로고
    • A nutritional model of late embryonic vitamin A deficiency produces defects in organogenesis at a high penetrance and reveals new roles for the vitamin in skeletal development
    • See, A. W.-M., Kaiser, M. E., White, J. C. Clagett-Dame, M. 2008. A nutritional model of late embryonic vitamin A deficiency produces defects in organogenesis at a high penetrance and reveals new roles for the vitamin in skeletal development. Dev. Biol. 316, 171 190.
    • (2008) Dev. Biol. , vol.316 , pp. 171-190
    • See, A.W.-M.1    Kaiser, M.E.2    White, J.C.3    Clagett-Dame, M.4
  • 108
    • 57849104554 scopus 로고    scopus 로고
    • The temporal requirement for vitamin A in the developing eye: Mechanism of action in optic fissure closure and new roles for the vitamin in regulating cell proliferation and adhesion in the embryonic retina
    • See, A. W. Clagett-Dame, M. 2009. The temporal requirement for vitamin A in the developing eye: mechanism of action in optic fissure closure and new roles for the vitamin in regulating cell proliferation and adhesion in the embryonic retina. Dev. Biol. 325, 94 105.
    • (2009) Dev. Biol. , vol.325 , pp. 94-105
    • See, A.W.1    Clagett-Dame, M.2
  • 109
    • 0029687085 scopus 로고    scopus 로고
    • Culture and microsurgical manipulation of the early avian embryo
    • ed. M. Bronner-Fraser. Academic Press
    • Selleck, M. A. J. 1996. Culture and microsurgical manipulation of the early avian embryo. In : Methods in Cell Biology. vol. 51. Methods in Avian Embryology (ed M. Bronner-Fraser pp. 1 21. Academic Press
    • (1996) Methods in Cell Biology. Vol. 51. Methods in Avian Embryology , pp. 1-21
    • Selleck, M.A.J.1
  • 110
    • 0028799948 scopus 로고
    • Maternal periconceptional use of multivitamins and reduced risk for conotruncal heart defects and limb deficiencies among offspring
    • Shaw, G. M., O'Malley, C. D., Wasserman, C. R., Tolarova, M.M. Lammer, E.J. 1955. Maternal periconceptional use of multivitamins and reduced risk for conotruncal heart defects and limb deficiencies among offspring. Am. J. Med. Genet. 59, 536 545.
    • (1955) Am. J. Med. Genet. , vol.59 , pp. 536-545
    • Shaw, G.M.1    O'Malley, C.D.2    Wasserman, C.R.3    Tolarova, M.M.4    Lammer, E.J.5
  • 111
    • 0142149220 scopus 로고    scopus 로고
    • Retinoic acid is a high affinity selective ligand for the peroxisome proliferator-activated receptor β/δ
    • Shaw, N., Elholm, M. Noy, N. 2003. Retinoic acid is a high affinity selective ligand for the peroxisome proliferator-activated receptor β/δ. J. Biol. Chem. 278, 41589 41592.
    • (2003) J. Biol. Chem. , vol.278 , pp. 41589-41592
    • Shaw, N.1    Elholm, M.2    Noy, N.3
  • 112
    • 0036148747 scopus 로고    scopus 로고
    • Whole-mount immunohistochemistry: A high-throughput screen for pattering defects in the mouse cerebellum
    • Sillitoe, R. V. Hawkes, R. 2002. Whole-mount immunohistochemistry: a high-throughput screen for pattering defects in the mouse cerebellum. J. Histochem. Cytochem. 50, 235 244.
    • (2002) J. Histochem. Cytochem. , vol.50 , pp. 235-244
    • Sillitoe, R.V.1    Hawkes, R.2
  • 113
    • 44949239539 scopus 로고    scopus 로고
    • Retinoic acid controls heart anteroposterior patterning by down-regulating Isl1 through the Fgf8 pathway
    • Sirbu, I. O., Zhao, X. Duester, G. 2008. Retinoic acid controls heart anteroposterior patterning by down-regulating Isl1 through the Fgf8 pathway. Dev. Dyn. 237, 1627 1635.
    • (2008) Dev. Dyn. , vol.237 , pp. 1627-1635
    • Sirbu, I.O.1    Zhao, X.2    Duester, G.3
  • 114
    • 0028013294 scopus 로고
    • Experimental specification of cell sorting, tissue spreading, and specific spatial patterning by quantitative differences in cadherin expression
    • Steinberg, M. S. Takeichi, M. 1994. Experimental specification of cell sorting, tissue spreading, and specific spatial patterning by quantitative differences in cadherin expression. Proc. Natl. Acad. Sci. USA 91, 206 209.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 206-209
    • Steinberg, M.S.1    Takeichi, M.2
  • 115
    • 0142011081 scopus 로고    scopus 로고
    • Epidermal growth factors promote endocardial precursor cell formation from precardiac mesoderm
    • Sugi, Y. Markwald, R. R. 2003. Epidermal growth factors promote endocardial precursor cell formation from precardiac mesoderm. Dev. Biol. 263, 35 49.
    • (2003) Dev. Biol. , vol.263 , pp. 35-49
    • Sugi, Y.1    Markwald, R.R.2
  • 116
    • 0036142502 scopus 로고    scopus 로고
    • Retinoids and their receptors in cancer development and chemoprevention
    • Sun, S. Y. Lotan, R. 2002. Retinoids and their receptors in cancer development and chemoprevention. Crit. Rev. Oncol. Hematol. 41, 41 55.
    • (2002) Crit. Rev. Oncol. Hematol. , vol.41 , pp. 41-55
    • Sun, S.Y.1    Lotan, R.2
  • 117
    • 0032714961 scopus 로고    scopus 로고
    • Complementary domains of retinoic acid production and degradation in the early chick embryo
    • Swindell, E. C., Thaller, C., Sockanathan, S., Petkovich, M., Jessel, T. M. Eichele, G. 1999. Complementary domains of retinoic acid production and degradation in the early chick embryo. Dev. Biol. 216, 286 296.
    • (1999) Dev. Biol. , vol.216 , pp. 286-296
    • Swindell, E.C.1    Thaller, C.2    Sockanathan, S.3    Petkovich, M.4    Jessel, T.M.5    Eichele, G.6
  • 118
    • 0028913743 scopus 로고
    • Anti-retinoic acid monoclonal antibody localizes all-trans-retinoic acid in target cells and blocks normal development in early quail embryo
    • Twal, W. O., Roze, L. Zile, M. H. 1995. Anti-retinoic acid monoclonal antibody localizes all-trans-retinoic acid in target cells and blocks normal development in early quail embryo. Dev. Biol. 168, 225 234.
    • (1995) Dev. Biol. , vol.168 , pp. 225-234
    • Twal, W.O.1    Roze, L.2    Zile, M.H.3
  • 119
    • 70349174901 scopus 로고    scopus 로고
    • Bmp2 and Bmp4 genetically interact to support multiple aspects of mouse development including functional heart development
    • Uchimura, T., Komatsu, Y., Tanaka, M., McCann, K. L. Mishina, Y. 2009. Bmp2 and Bmp4 genetically interact to support multiple aspects of mouse development including functional heart development. Genesis 47, 374 384.
    • (2009) Genesis , vol.47 , pp. 374-384
    • Uchimura, T.1    Komatsu, Y.2    Tanaka, M.3    McCann, K.L.4    Mishina, Y.5
  • 121
    • 0032589592 scopus 로고    scopus 로고
    • Expression of TGFβ3 RNA during chick embryogenesis: A possible important role in cardiovascular development
    • Yamagishi, T., Nakajima, Y. Nakamura, H. 1999. Expression of TGFβ3 RNA during chick embryogenesis: a possible important role in cardiovascular development. Cell. Tissue. Res. 298, 85 93.
    • (1999) Cell. Tissue. Res. , vol.298 , pp. 85-93
    • Yamagishi, T.1    Nakajima, Y.2    Nakamura, H.3
  • 122
    • 0031858069 scopus 로고    scopus 로고
    • Retinoids potentiate transforming growth factor-β activity in bovine endothelial cells through up-regulating the expression of transforming growth factor-beta receptors
    • Yoshizawa, M., Miyazaki, H. Kojima, S. 1998. Retinoids potentiate transforming growth factor-β activity in bovine endothelial cells through up-regulating the expression of transforming growth factor-beta receptors. J. Cell. Physiol. 176, 565 573.
    • (1998) J. Cell. Physiol. , vol.176 , pp. 565-573
    • Yoshizawa, M.1    Miyazaki, H.2    Kojima, S.3
  • 123
    • 0141594935 scopus 로고    scopus 로고
    • From developmental disorder to heritable cancer: It's all in the BMP/TGF-β family
    • Waite, K. A. Eng, C. 2003. From developmental disorder to heritable cancer: it's all in the BMP/TGF-β family. Nat. Rev. Genet. 4, 763 773.
    • (2003) Nat. Rev. Genet. , vol.4 , pp. 763-773
    • Waite, K.A.1    Eng, C.2
  • 125
    • 84958699162 scopus 로고
    • An analysis of the syndrome of malformations induced by maternal vitamin A deficiency. Effects of restoration of vitamin A at various times during gestation
    • Wilson, J. G., Roth, C. B. Warkany, J. 1953. An analysis of the syndrome of malformations induced by maternal vitamin A deficiency. Effects of restoration of vitamin A at various times during gestation. Am. J. Anat. 92, 189 217.
    • (1953) Am. J. Anat. , vol.92 , pp. 189-217
    • Wilson, J.G.1    Roth, C.B.2    Warkany, J.3
  • 126
    • 0033562350 scopus 로고    scopus 로고
    • Development and validation of real- time quantitative reverse transcriptase-polymerase chain reaction for monitoring gene expression in cardiac myocytes in vitro
    • Winer, J., Jung, C. K., Shackel, I. Williams, P. M. 1999. Development and validation of real- time quantitative reverse transcriptase-polymerase chain reaction for monitoring gene expression in cardiac myocytes in vitro. Anal. Biochem. 270, 41 49.
    • (1999) Anal. Biochem. , vol.270 , pp. 41-49
    • Winer, J.1    Jung, C.K.2    Shackel, I.3    Williams, P.M.4
  • 128
    • 61749097816 scopus 로고    scopus 로고
    • TGF-β superfamily signaling in embryonic development and homeostasis
    • Wu, M. Y. Hill, C. S. 2009. TGF-β superfamily signaling in embryonic development and homeostasis. Dev. Cell. 16, 329 343.
    • (2009) Dev. Cell. , vol.16 , pp. 329-343
    • Wu, M.Y.1    Hill, C.S.2
  • 130
    • 0035437861 scopus 로고    scopus 로고
    • Elevated TGFβ signaling inhibits ocular vascular development
    • Zhao, S. Overbeek, P. A. 2001. Elevated TGFβ signaling inhibits ocular vascular development. Dev. Biol. 237, 45 53.
    • (2001) Dev. Biol. , vol.237 , pp. 45-53
    • Zhao, S.1    Overbeek, P.A.2
  • 131
    • 0025859199 scopus 로고
    • Production of a hybridoma cell line secreting retinoic acid- specific monoclonal antibody
    • Zhou, H.-R., Abouzied, M. M. Zile, M. H. 1991. Production of a hybridoma cell line secreting retinoic acid- specific monoclonal antibody. J. Immunol. Methods 138, 211 223.
    • (1991) J. Immunol. Methods , vol.138 , pp. 211-223
    • Zhou, H.-R.1    Abouzied, M.M.2    Zile, M.H.3
  • 133
    • 0034662279 scopus 로고    scopus 로고
    • Retinoid signaling is required to complete the vertebrate cardiac left/right asymmetry pathway
    • Zile, M. H., Kostetskii, I., Yuan, S., Kostetskaia, E., St. Amand, T. R., Chen, Y. Jiang, W. 2000. Retinoid signaling is required to complete the vertebrate cardiac left/right asymmetry pathway. Dev. Biol. 223, 323 338.
    • (2000) Dev. Biol. , vol.223 , pp. 323-338
    • Zile, M.H.1    Kostetskii, I.2    Yuan, S.3    Kostetskaia, E.4    St. Amand, T.R.5    Chen, Y.6    Jiang, W.7
  • 134
    • 3042770825 scopus 로고    scopus 로고
    • Vitamin A requirement for early cardiovascular morphogenesis specification in the vertebrate embryo: Insights from the avian embryo
    • Zile, M. H. 2004. Vitamin A requirement for early cardiovascular morphogenesis specification in the vertebrate embryo: insights from the avian embryo. J. Exp. Biol. Med. 229, 598 606.
    • (2004) J. Exp. Biol. Med. , vol.229 , pp. 598-606
    • Zile, M.H.1
  • 135
    • 0035974426 scopus 로고    scopus 로고
    • Transforming growth factor β signalling in vitro and in vivo: Activin ligand-receptor interaction, Smad5 in vasculogenesis, and repression of target genes by δeFI/ZEB-related SIP1 in the vertebrate embryo
    • Zwijsen, A., van Grunsven, L. A., Bosman, E. A., Collart, C., Nelles, L., Umans, L., Van de Putte, T., Wuytens, G., Huylebroeck, D. Verschueren, K. 2001. Transforming growth factor β signalling in vitro and in vivo: activin ligand-receptor interaction, Smad5 in vasculogenesis, and repression of target genes by δEFI/ZEB-related SIP1 in the vertebrate embryo. Mol. Cell. Endocrinol. 180, 13 24.
    • (2001) Mol. Cell. Endocrinol. , vol.180 , pp. 13-24
    • Zwijsen, A.1    Van Grunsven, L.A.2    Bosman, E.A.3    Collart, C.4    Nelles, L.5    Umans, L.6    Van De Putte, T.7    Wuytens, G.8    Huylebroeck, D.9    Verschueren, K.10


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