The effect of protective agents on the stability of plasmid DNA by the process of spray-drying

Journal of Pharmacy and Pharmacology

Volumn 55, Issue 3, 2003, Pages 301-306

  Kuo, Jung Hua Steven ^a  

^a CHIA NAN UNIVERSITY OF PHARMACY AND SCIENCE   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

AGAROSE; GLYCINE; MACROGOL; MACROGOL 1000; MACROGOL 4000; PLASMID DNA; PROTECTIVE AGENT; SUCROSE; UNCLASSIFIED DRUG;

AGAR GEL ELECTROPHORESIS; ARTICLE; DNA DEGRADATION; DNA STRUCTURE; DNA SUPERCOILING; DRUG EFFECT; PROTECTION; PROTEIN LOCALIZATION; PROTEIN STABILITY; PROTEIN TERTIARY STRUCTURE; SPRAY DRYING; STORAGE TEMPERATURE;

DESICCATION; DNA; ELECTROPHORESIS, AGAR GEL; ESCHERICHIA COLI; GLYCINE; PLASMIDS; POLYETHYLENE GLYCOLS; POLYETHYLENEIMINE; SEPHAROSE; STRESS, MECHANICAL; SUCROSE; SURFACE-ACTIVE AGENTS; TEMPERATURE;

EID: 0037355596     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1211/002235702702     Document Type: Article

References (28)

1. Adam, R. E., Zimm, B. H. (1977) Shear degradation of DNA. Nucleic Acids Res. 4: 1513-1537
2. Adami, R. C., Collard, W. T., Gupta, S. A., Kwok, K. Y., Bonadio, J., Rice, K. G. (1998) Stability of peptide-condensed plasmid DNA formulations. J. Pharm. Sci. 87: 678-683
3. Anchordoquy, T. J., Koe, G. S. (2000) Physical stability of non-viral plasmid-based therapeutics. J. Pharm. Sci. 89: 289-296
4. Bloomfield, V. A. (1996) DNA condensation. Curr. Opin. Struct. Biol. 6: 334-341
5. Boussif, O., Lezoualch, F., Zanta, M. A., Mergny, M. D., Scherman, D., Demeneix, B. Behr, J.-P. (1995) A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: Polyethylenimine. Proc. Natl. Acad. Sci. USA 92: 7297-7301
6. Broadhead, J., Edmond Rouan, S. K., Hau, I. (1994) The effect of process and formulation variables on the properties of spray-dried β-galactosidase. J. Pharm. Pharmacol. 46: 458-467
7. Carpenter, J. F., Crowe, J. H. (1989) An infrared spectroscopic study of the interactions of carbohydrates with dried proteins. Biochemistry 28: 3916-3922
8. Freeman, D. J., Niven, R. W. (1996) The influence of sodium glycocholate and other additives on the in vivo transfection of plasmid DNA in the lungs. Pharm. Res. 13: 202-209
9. Gebhart, C. L., Kabanov, A. V. (2001) Evaluation of polyplexes as gene transfer agents. J. Control. Release 73: 401-416
10. Kimoto, H., Taketo, A. (1996) Studies of electrotransfer of DNA into Escherichia coli: Effect of molecular form of DNA. Biochim. Biophys. Acta 1307: 325-330.
11. Kuo, J.-H., Lo, Y.-L., Shau, M.-D., Cherng, J.-Y. (2002) A thermodynamic study of cationic polymer-plasmid DNA complexes by high-sensitive differential scanning calorimetry. J. Control. Release 81: 321-325
12. Labrude, P., Rasolomanana, M., Vigneron, C., Thirion, C., Chaillot, B. (1989) Protective effect of sucrose on spray drying of oxyhemoglobin. J. Pharm. Sci. 78: 223-229
13. Levy, M. S., Collins, I. J., Yim, S. S., Ward, J. M., Titchener-Hooker, N., Shamlou, P. A., Dunnill, P. (1999) Effect of shear on plasmid DNA in solution. Bioprocess Eng. 20: 7-13
14. Lindahl, T., Karlstrom, O. (1973) Heat-induced depyrimidination of deoxyribonucleic acid in neutral solution. Biochemistry 12: 5151-5154
15. Lobo, B. A., Rogers, S. A., Choosakoonriang S., Smith, J. G., Koe, G., Middlaugh C. R. (2002) Differential scanning calorimetric studies of the thermal stability of plasmid DNA complexed with cationic lipids and polymers. J. Pharm. Sci. 91: 454-466
16. Maa, Y.-F., Hsu, C. C. (2002) Protein denaturation by combined effect of shear and air-liquid interface. Biotechnol. Bioeng. 54: 503-512
17. Maa Y.-F., Nguyen, P.-A., Andyan, J. D., Dasovich, N., Sweeney, T. D., Shire, S. J., Hsu C. C. (1998) Effect of spray drying and subsequent processing conditions on residual moisture content and physical/biochemical stability of protein inhalation powders. Pharm. Res. 15: 768-775
18. Master, K. (1991) In: Spray Drying Handbook. Fifth edn, Longman Scientific & Technical, London, pp. 1-66
19. Middaugh, C. R., Evans, R. K., Montgomery, D. L., Casimiro, D. R. (1998) Analysis of plasmid DNA from a pharmaceutical perspective. J. Pharm. Sci. 87: 130-146
20. Miller. A. D. (1992) Human gene therapy comes of age. Nature 357: 455-460
21. Niven, R., Ip, A., Mittlemann, S., Farrar, C., Arakawa, T., Prestrelski, S. (1994) Stability of lactate dehydrogenase and recombinant granulocyte colony stimulating factor to air-jet nebulization. Int. J. Pharm. 109: 17-26
22. Reese, H. R., Zimm B. H. (1990) Fracture of polymer chains in extensional flow: Experiments with DNA, and a molecular-dynamics simulation. J. Chem. Phys. 92: 2650-2662
23. Sambrook, J., Russel, D. W. (2001) In: Molecular Cloning: A Laboratory Manual. Third edn, Third edn, Cold Spring Harbor Laboratory Press, New York, Chapter 2, p. 110
24. Suzuki, T.,Ohsumi, S., Makino, K. (1994) Mechanistic studies on depurination and apurinic site chain breakage in oligodeoxy-ribonucleotides. Nucleic Acids Res. 22: 4997-5003
25. Trubetskoy, V. S., Loomis, A., Hagstrom, J. E., Budker, V. G., Wolff, J. A. (1999) Layer-by-layer deposition of oppositely charged polyelectrolytes on the surface of condensed DNA particles. Nucleic Acids Res. 27: 3090-3095
26. Vasilevskaya, V. V., Khokhlov, A. R., Matsuzawa, Y., Yoshikawa, K. (1995) Collapse of single DNA molecule in poly(ethylene glycol) solutions. J. Chem. Phys. 102: 6595-6602
27. Walsh, G. (1998) In: Biopharmaceuticals: Biochemistry and Biotechnology. John Wiley & Sons Ltd, UK, pp. 122-123
28. Xie, T. D., Tsong, T. Y. (1993) Study of mechanisms of electric field-induced DNA transfection. V. Effects of DNA topology on surface binding, cell uptake, expression, and integration into host chromosomes of DNA in the mammalian cell. Biophys. J. 65: 1685-1689