-
1
-
-
0031758671
-
Heparin and low-molecular-weight heparin: mechanisms of action, pharmacokinetics, dosing considerations, monitoring, efficacy, and safety
-
Hirsh J., Warkentin T., Raschke R., Granger C., Ohman E., and Dalen J. Heparin and low-molecular-weight heparin: mechanisms of action, pharmacokinetics, dosing considerations, monitoring, efficacy, and safety. Chest 114 (1998) 489-510
-
(1998)
Chest
, vol.114
, pp. 489-510
-
-
Hirsh, J.1
Warkentin, T.2
Raschke, R.3
Granger, C.4
Ohman, E.5
Dalen, J.6
-
2
-
-
1142309794
-
In situ intestinal absorption studies on low molecular weight heparin in rats using Labrasol as absorption enhancer
-
Prasad Y., Minamimoto T., Yoshikawa Y., Shibata N., Mori S., Matsuura A., and Takada K. In situ intestinal absorption studies on low molecular weight heparin in rats using Labrasol as absorption enhancer. Int. J. Pharm. 271 (2004) 225-232
-
(2004)
Int. J. Pharm.
, vol.271
, pp. 225-232
-
-
Prasad, Y.1
Minamimoto, T.2
Yoshikawa, Y.3
Shibata, N.4
Mori, S.5
Matsuura, A.6
Takada, K.7
-
3
-
-
21744442224
-
Gastrointestinal absorption of heparin by lipidization or coadministration with penetration enhancers
-
Ross B., and Toth I. Gastrointestinal absorption of heparin by lipidization or coadministration with penetration enhancers. Curr. Drug Deliv. 2 (2005) 277-287
-
(2005)
Curr. Drug Deliv.
, vol.2
, pp. 277-287
-
-
Ross, B.1
Toth, I.2
-
4
-
-
20344385254
-
Oral heparin delivery: design and in vivo evaluation of a stomach-targeted mucoadhesive delivery system
-
Schmitz T., Leitner V., and Bernkop-Schnürch A. Oral heparin delivery: design and in vivo evaluation of a stomach-targeted mucoadhesive delivery system. J. Pharm. Sci. 94 (2005) 966-973
-
(2005)
J. Pharm. Sci.
, vol.94
, pp. 966-973
-
-
Schmitz, T.1
Leitner, V.2
Bernkop-Schnürch, A.3
-
5
-
-
32044444307
-
Oral delivery of chemical conjugates of heparin and deoxycholic acid in aqueous formulation
-
Kim S., Vaishali B., Lee E., Lee S., Lee Y., Kumar T., Moon H., and Byuna Y. Oral delivery of chemical conjugates of heparin and deoxycholic acid in aqueous formulation. Thromb. Res. 117 (2006) 419-427
-
(2006)
Thromb. Res.
, vol.117
, pp. 419-427
-
-
Kim, S.1
Vaishali, B.2
Lee, E.3
Lee, S.4
Lee, Y.5
Kumar, T.6
Moon, H.7
Byuna, Y.8
-
6
-
-
33744538237
-
Oral bioavailability of a low molecular weight heparin using a polymeric delivery system
-
Hoffart V., Lamprecht A., Maincent P., Lecompte T., Vigneron C., and Ubrich N. Oral bioavailability of a low molecular weight heparin using a polymeric delivery system. J. Control. Release 113 (2006) 38-42
-
(2006)
J. Control. Release
, vol.113
, pp. 38-42
-
-
Hoffart, V.1
Lamprecht, A.2
Maincent, P.3
Lecompte, T.4
Vigneron, C.5
Ubrich, N.6
-
7
-
-
33646555163
-
Self-assembled polyelectrolyte nanocomplexes between chitosan derivatives and insulin
-
Mao S., Bakowsky U., Jintapattanakit A., and Kissel T. Self-assembled polyelectrolyte nanocomplexes between chitosan derivatives and insulin. J. Pharm. Sci. 95 (2006) 1035-1048
-
(2006)
J. Pharm. Sci.
, vol.95
, pp. 1035-1048
-
-
Mao, S.1
Bakowsky, U.2
Jintapattanakit, A.3
Kissel, T.4
-
8
-
-
34447263071
-
Chitosan/cyclodextrin nanoparticles as macromolecular drug delivery system
-
Krauland A., and Alonso M. Chitosan/cyclodextrin nanoparticles as macromolecular drug delivery system. Int. J. Pharm. 340 (2007) 134-142
-
(2007)
Int. J. Pharm.
, vol.340
, pp. 134-142
-
-
Krauland, A.1
Alonso, M.2
-
9
-
-
0344505867
-
The enhancement of the bioadhesive properties of calcium alginate gel beads by coating with chitosan
-
Gaserod O., Jolliffe I.G., Hampson F.C., Dettmar P.W., and Skjak-Braek G. The enhancement of the bioadhesive properties of calcium alginate gel beads by coating with chitosan. Int. J. Pharm. 175 (1998) 237-246
-
(1998)
Int. J. Pharm.
, vol.175
, pp. 237-246
-
-
Gaserod, O.1
Jolliffe, I.G.2
Hampson, F.C.3
Dettmar, P.W.4
Skjak-Braek, G.5
-
10
-
-
0035940314
-
Chitosan as a novel nasal delivery system for vaccines
-
Illum L., Jabbal-Gill I., Hinchcliffe M., Fisher A.N., and Davis S.S. Chitosan as a novel nasal delivery system for vaccines. Adv. Drug Deliv. Rev. 51 (2001) 81-96
-
(2001)
Adv. Drug Deliv. Rev.
, vol.51
, pp. 81-96
-
-
Illum, L.1
Jabbal-Gill, I.2
Hinchcliffe, M.3
Fisher, A.N.4
Davis, S.S.5
-
11
-
-
0037472115
-
Chitosan-based gastrointestinal delivery systems
-
Hejazi R., and Amiji M. Chitosan-based gastrointestinal delivery systems. J. Control. Release 89 (2003) 151-165
-
(2003)
J. Control. Release
, vol.89
, pp. 151-165
-
-
Hejazi, R.1
Amiji, M.2
-
12
-
-
0033991816
-
Chitosan and its derivatives: potential excipients for peroral peptide delivery systems
-
Bernkop-Schnürch A. Chitosan and its derivatives: potential excipients for peroral peptide delivery systems. Int. J. Pharm. 194 (2000) 1-13
-
(2000)
Int. J. Pharm.
, vol.194
, pp. 1-13
-
-
Bernkop-Schnürch, A.1
-
13
-
-
20444441841
-
Synthesis, characterization and cytotoxicity of poly(ethylene glycol)-graft-trimethyl chitosan block copolymer
-
Mao S., Shuai X., Unger F., Wittmar M., Xie X., and Kissel T. Synthesis, characterization and cytotoxicity of poly(ethylene glycol)-graft-trimethyl chitosan block copolymer. Biomaterials 26 (2005) 6343-6356
-
(2005)
Biomaterials
, vol.26
, pp. 6343-6356
-
-
Mao, S.1
Shuai, X.2
Unger, F.3
Wittmar, M.4
Xie, X.5
Kissel, T.6
-
14
-
-
29244468833
-
Uptake and transport of PEG-graft-trimethyl-chitosan copolymer-insulin nanocomplexes by epithelial cells
-
Mao S., Germershaus O., Fischer D., Linn T., Schnepf R., and Kissel T. Uptake and transport of PEG-graft-trimethyl-chitosan copolymer-insulin nanocomplexes by epithelial cells. Pharm. Res. 22 (2005) 2058-2068
-
(2005)
Pharm. Res.
, vol.22
, pp. 2058-2068
-
-
Mao, S.1
Germershaus, O.2
Fischer, D.3
Linn, T.4
Schnepf, R.5
Kissel, T.6
-
15
-
-
33646814008
-
Elaboration and characterization of thiolated chitosan-coated acrylic nanoparticles
-
Bravo-Osuna I., Schmitz T., Bernkop-Schnürch A., Vauthier C., and Ponchel G. Elaboration and characterization of thiolated chitosan-coated acrylic nanoparticles. Int. J. Pharm. 316 (2006) 170-175
-
(2006)
Int. J. Pharm.
, vol.316
, pp. 170-175
-
-
Bravo-Osuna, I.1
Schmitz, T.2
Bernkop-Schnürch, A.3
Vauthier, C.4
Ponchel, G.5
-
16
-
-
0343137650
-
Polyelectrolyte complex of heparin with chitosan
-
Kikuchi Y. Polyelectrolyte complex of heparin with chitosan. Makromol. Chem. 175 (1974) 2209-2211
-
(1974)
Makromol. Chem.
, vol.175
, pp. 2209-2211
-
-
Kikuchi, Y.1
-
17
-
-
3543051289
-
The depolymerization of chitosan: effects on physicochemical and biological properties
-
Mao S., Shuai X., Unger F., Simon M., Bi D., and Kissel T. The depolymerization of chitosan: effects on physicochemical and biological properties. Int. J. Pharm. 281 (2004) 45-54
-
(2004)
Int. J. Pharm.
, vol.281
, pp. 45-54
-
-
Mao, S.1
Shuai, X.2
Unger, F.3
Simon, M.4
Bi, D.5
Kissel, T.6
-
18
-
-
0032114947
-
Preparation and NMR characterization of highly substituted N-trimethyl chitosan chloride
-
Sieval A.B., Thanou M., Kotze A.F., Verhoef J.C., Brussee J., and Junginger H.E. Preparation and NMR characterization of highly substituted N-trimethyl chitosan chloride. Carbohydr. Polym. 36 (1998) 157-165
-
(1998)
Carbohydr. Polym.
, vol.36
, pp. 157-165
-
-
Sieval, A.B.1
Thanou, M.2
Kotze, A.F.3
Verhoef, J.C.4
Brussee, J.5
Junginger, H.E.6
-
20
-
-
0037080913
-
In vitro and in vivo evaluation of oral heparin-loaded polymeric nanoparticles in rabbits
-
Jiao Y., Ubrich N., Marchand-Arvier M., Vigneron C., Hoffman M., Lecompte T., and Maincent P. In vitro and in vivo evaluation of oral heparin-loaded polymeric nanoparticles in rabbits. Circulation 105 (2002) 230-235
-
(2002)
Circulation
, vol.105
, pp. 230-235
-
-
Jiao, Y.1
Ubrich, N.2
Marchand-Arvier, M.3
Vigneron, C.4
Hoffman, M.5
Lecompte, T.6
Maincent, P.7
-
21
-
-
33846452585
-
Tuning of shell and core characteristics of chitosan-decorated acrylic nanoparticles
-
Bravo-Osuna I., Ponchel G., and Vauthier C. Tuning of shell and core characteristics of chitosan-decorated acrylic nanoparticles. Eur. J. Pharm. Sci. 30 (2007) 143-154
-
(2007)
Eur. J. Pharm. Sci.
, vol.30
, pp. 143-154
-
-
Bravo-Osuna, I.1
Ponchel, G.2
Vauthier, C.3
-
22
-
-
26644452975
-
Thiomers: a new generation of mucoadhesive polymers
-
Bernkop-Schnürch A. Thiomers: a new generation of mucoadhesive polymers. Adv. Drug Deliv. Rev. 57 (2005) 1569-1582
-
(2005)
Adv. Drug Deliv. Rev.
, vol.57
, pp. 1569-1582
-
-
Bernkop-Schnürch, A.1
-
23
-
-
3843146208
-
Trimethylated chitosan as polymeric absorption enhancer for improved peroral delivery of peptide drugs
-
van der Merwe S.M., Verhoef J.C., Verheijden J.H.M., Kotze A.F., and Junginger H.E. Trimethylated chitosan as polymeric absorption enhancer for improved peroral delivery of peptide drugs. Eur. J. Pharm. Biopharm. 58 (2004) 225-235
-
(2004)
Eur. J. Pharm. Biopharm.
, vol.58
, pp. 225-235
-
-
van der Merwe, S.M.1
Verhoef, J.C.2
Verheijden, J.H.M.3
Kotze, A.F.4
Junginger, H.E.5
-
24
-
-
37349041646
-
In vitro and in vivo study of N-trimethyl chitosan nanoparticles for oral protein delivery
-
Chen F., Zhang Z., Yuan F., Qin X., Wang M., and Huang Y. In vitro and in vivo study of N-trimethyl chitosan nanoparticles for oral protein delivery. Int. J. Pharm. 349 (2008) 226-233
-
(2008)
Int. J. Pharm.
, vol.349
, pp. 226-233
-
-
Chen, F.1
Zhang, Z.2
Yuan, F.3
Qin, X.4
Wang, M.5
Huang, Y.6
-
25
-
-
0037219709
-
N-Trimethyl chitosan chloride: optimum degree of quaternization for drug absorption enhancement across epithelial cells
-
Hamman J.H., Schultz C.M., and Kotze A.F. N-Trimethyl chitosan chloride: optimum degree of quaternization for drug absorption enhancement across epithelial cells. Drug Dev. Ind. Pharm. 29 (2003) 161-172
-
(2003)
Drug Dev. Ind. Pharm.
, vol.29
, pp. 161-172
-
-
Hamman, J.H.1
Schultz, C.M.2
Kotze, A.F.3
-
26
-
-
34250901807
-
Chemical modification of chitosan as a gene carrier in vitro and in vivo
-
Kim T., Jiang H., Jere D., Park I., Cho M., Nah J., Choi Y., Akaike T., and Cho C. Chemical modification of chitosan as a gene carrier in vitro and in vivo. Prog. Polym. Sci. 32 (2007) 726-753
-
(2007)
Prog. Polym. Sci.
, vol.32
, pp. 726-753
-
-
Kim, T.1
Jiang, H.2
Jere, D.3
Park, I.4
Cho, M.5
Nah, J.6
Choi, Y.7
Akaike, T.8
Cho, C.9
-
27
-
-
33646472410
-
Design of poly(ethylene glycol)-tethered copolymers as novel mucoadhesive drug delivery systems
-
Serra L., Domenech J., and Peppas N.A. Design of poly(ethylene glycol)-tethered copolymers as novel mucoadhesive drug delivery systems. Eur. J. Pharm. Biopharm. 63 (2006) 11-18
-
(2006)
Eur. J. Pharm. Biopharm.
, vol.63
, pp. 11-18
-
-
Serra, L.1
Domenech, J.2
Peppas, N.A.3
-
28
-
-
0027113235
-
Effects of protein charge heterogeneity in protein-polyelectrolyte complexation
-
Park J.M., Muhoberac B.B., Dubin P.L., and Xia J. Effects of protein charge heterogeneity in protein-polyelectrolyte complexation. Macromolecules 25 (1992) 290-295
-
(1992)
Macromolecules
, vol.25
, pp. 290-295
-
-
Park, J.M.1
Muhoberac, B.B.2
Dubin, P.L.3
Xia, J.4
-
29
-
-
0035424424
-
In vitro gene delivery mediated by chitosan. Effect of pH, serum, and molecular mass of chitosan on the transfection efficiency
-
Sato T., Ishii T., and Okahata Y. In vitro gene delivery mediated by chitosan. Effect of pH, serum, and molecular mass of chitosan on the transfection efficiency. Biomaterials 22 (2001) 2075-2080
-
(2001)
Biomaterials
, vol.22
, pp. 2075-2080
-
-
Sato, T.1
Ishii, T.2
Okahata, Y.3
-
30
-
-
0346724871
-
Structure and interactions in chitosan hydrogels formed by complexation or aggregation for biomedical applications
-
Berger J., Reist M., Mayer J.M., Felt O., and Gurny R. Structure and interactions in chitosan hydrogels formed by complexation or aggregation for biomedical applications. Eur. J. Pharm. Biopharm. 57 (2004) 35-52
-
(2004)
Eur. J. Pharm. Biopharm.
, vol.57
, pp. 35-52
-
-
Berger, J.1
Reist, M.2
Mayer, J.M.3
Felt, O.4
Gurny, R.5
-
31
-
-
0025860875
-
a of glucuronic acid and the carboxy groups of heparin by carbon-13 nuclear magnetic resonance spectroscopy
-
a of glucuronic acid and the carboxy groups of heparin by carbon-13 nuclear magnetic resonance spectroscopy. Biochem. J. 278 (1991) 689-695
-
(1991)
Biochem. J.
, vol.278
, pp. 689-695
-
-
Wang, H.1
Loganathan, D.2
Linhardt, R.3
-
32
-
-
0030983071
-
Applications of the ion-pair concept to hydrophilic substances with special emphasis on peptides
-
Quintanar-Guerrero D., Allemann E., Fessi H., and Doelker E. Applications of the ion-pair concept to hydrophilic substances with special emphasis on peptides. Pharm. Res. 14 (1997) 119-127
-
(1997)
Pharm. Res.
, vol.14
, pp. 119-127
-
-
Quintanar-Guerrero, D.1
Allemann, E.2
Fessi, H.3
Doelker, E.4
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