Mitochondrial ion channels as therapeutic targets

FEBS Letters

Volumn 584, Issue 10, 2010, Pages 2142-2152

  Peixoto, Pablo M ^a   Ryu, Shin Young ^a   Kinnally, Kathleen W ^a  

^a NEW YORK UNIVERSITY COLLEGE OF DENTISTRY   (United States)

Author keywords

Mitochondrial disease; Mitochondrial ion channels; Patch clamp; Therapy

Indexed keywords

4 [4 (4' CHLORO 2 BIPHENYLYLMETHYL) 1 PIPERAZINYL] N [4 [3 DIMETHYLAMINO 1 (PHENYLTHIOMETHYL)PROPYLAMINO] 3 NITROBENZENESULFONYL]BENZAMIDE; 4 [4 [2 (4 CHLOROPHENYL) 5,5 DIMETHYL 1 CYCLOHEXEN 1 YLMETHYL] 1 PIPERAZINYL] N [4 [3 MORPHOLINO 1 (PHENYLTHIOMETHYL)PROPYLAMINO] 3 (TRIFLUOROMETHYLSULFONYL)BENZENESULFONYL]BENZAMIDE; ALKALINE INDUCED ANION SELECTIVE ACTIVITY; ALKALINE INDUCED CATION SELECTIVE ACTIVITY; ANION CHANNEL; CALCIUM; CALCIUM CHANNEL; CYCLOPHILIN D; CYCLOSPORIN A; CYTOCHROME C; INTRACELLULAR CHLORIDE CHANNEL; ION CHANNEL; JASMONIC ACID METHYL ESTER; MITOCHONDRIAL PERMEABILITY TRANSITION PORE; MITOCHONDRIAL PROTEIN; N (4 CHLOROPHENYL) N' CYANO N'' (6 CYANO 3,4 DIHYDRO 3 HYDROXY 2,2 DIMETHYL 2H 1 BENZOPYRAN 4 YL)GUANIDINE; NUCLEAR PROTEIN; OBLIMERSEN; POTASSIUM; PROTEIN BAK; PROTEIN BAX; PROTEIN BCL 2; PROTEIN TIM21; PROTEIN TIM23; PROTEIN TOM; PROTON; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; UNCLASSIFIED DRUG; VOLTAGE DEPENDENT ANION CHANNEL; VOLTAGE DEPENDENT ANION CHANNEL 3;

APOPTOSIS; BETA SHEET; CELL FUNCTION; CELL PERMEABILIZATION; CLINICAL TRIAL; DRUG PROTEIN BINDING; ENZYME INHIBITION; ENZYME RELEASE; HEART PROTECTION; HUMAN; MEMBRANE CONDUCTANCE; MITOCHONDRIAL MEMBRANE; MITOCHONDRION; MUSCULAR DYSTROPHY; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; PROTEIN TARGETING; PROTEIN TRANSPORT; REVIEW;

ANIMALS; APOPTOSIS; CALCIUM CHANNELS; HUMANS; ION CHANNELS; MITOCHONDRIA; POTASSIUM CHANNELS; VOLTAGE-DEPENDENT ANION CHANNELS;

EID: 77952670367     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2010.02.046     Document Type: Review

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