Awaking TIM22, a dynamic ligand-gated channel for protein insertion in the mitochondrial inner membrane

Journal of Biological Chemistry

Volumn 282, Issue 26, 2007, Pages 18694-18701

  Peixoto, Pablo M V ^a   Graña, Fernando ^a   Roy, Teresa J ^a   Dunn, Cory D ^b   Flores, Montaña ^a   Jensen, Robert E ^b   Campo, María Luisa ^a  

^a UNIVERSITY OF EXTREMADURA   (Spain)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MITOCHONDRIAL MEMBRANES; MULTITOPIC PROTEINS; PROTEIN INSERTION; TRANSLOCASE OF THE OUTER MEMBRANE (TOM);

BIOACTIVITY; CELL MEMBRANES; COMPLEXATION; LIGANDS; PEPTIDES;

ENZYMES;

CARRIER PROTEIN; MEMBRANE PROTEIN; PROTEIN TIM22; SIGNAL PEPTIDE; TRANSLOCASE OF INNER MEMBRANE 22; TRANSLOCASE OF OUTER MEMBRANE; UNCLASSIFIED DRUG;

ARTICLE; CELLULAR DISTRIBUTION; CHEMICAL COMPOSITION; COMPARATIVE STUDY; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME SUBSTRATE; ION CONDUCTANCE; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; MOLECULAR DYNAMICS; NONHUMAN; POROSITY; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION;

ION CHANNEL GATING; LIGANDS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MEMBRANE TRANSPORT PROTEINS; MITOCHONDRIAL MEMBRANES; PATCH-CLAMP TECHNIQUES; PROTEIN CONFORMATION; PROTEIN SORTING SIGNALS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SIGNAL TRANSDUCTION;

EID: 34547100322     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M700775200     Document Type: Article

References (44)

1. Reichert, A. S., and Neupert, W. (2004) Trends Genet. 20, 555-562
2. Hoogenraad, N. J., Ward, L. A., and Ryan, M. T. (2002) Biochim. Biophys. Acta Mol. Cell Res. 1592, 97-105
3. Truscott, K. N., Brandner, K., and Pfanner, N. (2003) Curr. Biol. 13, R326-R337
4. Wiedemann, N., Frazier, A. E., and Pfanner, N. (2004) J. Biol. Chem. 279, 14473-14476
5. Pfanner, N., and Wiedemann, N. (2002) Curr. Opin. Cell Biol. 14, 400-411
6. Peixoto, P. M., Martinez-Caballero, S., Grigoriev, S. M., Kinnally, K. W., and Campo, M. L. (2004) Recent Research Developments in Biophysics, Vol. 3, pp. 413-474, Transworld Research Network, Kerala, India
7. Grigoriev, S. M., Muro, C., Dejean, L. M., Campo, M. L., Martinez-Caballero, S., and Kinnally, K. W. (2004) Int. Rev. Cytol. 238, 227-274
8. Taylor, R. D., and Pfanner, N. (2004) Biochim. Biophys. Acta, Bioenerg. 1658, 37-43
9. Chacinska, A., Lind, M., Frazier, A. E., Dudek, J., Meisinger, C., Geissler, A., Sickmann, A., Meyer, H. E., Truscott, K. N., and Guiard, B. (2005) Cell 120, 817-829
10. Koehler, C. M., Merchant, S., and Schatz, G. (1999) Trends Biochem. Sci. 24, 428-432
11. Paschen, S. A., Rothbauer, U., Kaldi, K., Bauer, M. F., Neupert, W., and Brunner, M. (2000) EMBO J. 19, 6392-6400
12. Koehler, C. M., Merchant, S., Oppliger, W., Schmid, K., Jarosch, E., Dolfini, L., Junne, T., Schatz, G., and Tokatlidis, K. (1998) EMBO J. 17, 6477-6486
13. Koehler, C. M. (2004) Annu. Rev. Cell Dev. Biol. 20, 309-335
14. Adam, A., Endres, M., Sirrenberg, C., Lottspeich, F., Neupert, W., and Brunner, M. (1999) EMBO J. 18, 313-319
15. Sirrenberg, C., Endres, M., Folsch, H., Stuart, R. A., Neupert, W., and Brunner, M. (1998) Cell 391, 912-915
16. Kerscher, O., Holder, J., Srinivasan, M., Leung, R. S., and Jensen, R. E. (1997) J. Cell Biol. 139, 1663-1675
17. Kerscher, O., Sepuri, N. B., and Jensen, R. E. (2000) Mol. Biol. Cell 11, 103-116
18. Muro, C., Grigoriev, S. M., Pietkiewicz, D., Kinnally, K. W., and Campo, M. L. (2003) Biophys. J. 84, 2981-2989
19. Martínez-Caballero, S., Grigoriev, S. M., Herrmann, J. M., Campo, M. L., and Kinnally, K. W. (2007) J. Biol. Chem. 282, 3584-3593
20. Kovermann, P., Truscott, K. N., Guiard, B., Rehling, P., Sepuri, N. B., Muller, H., Jensen, R. E., Wagner, R., and Pfanner, N. (2002) Mol. Cell 9, 363-373
21. Rehling, P., Model, K., Brandner, K., Kovermann, P., Meyer, H. E., Kuhlbrandt, W., Wagner, R., Truscott, K. N., and Pfanner, N. (2003) Science 299, 1747-1751
22. Milisav, I., Moro, F., Neupert, W., and Brunner, M. (2001) J. Biol. Chem. 276, 25856-25861
23. Ohba, M., and Schatz, G. (1987) EMBO J. 6, 2117-2122
24. Mannella, C. A. (1982) J. Cell Biol. 94, 680-687
25. Lohret, T. A., Jensen, R. E., and Kinnally, K. W. (1997) J. Cell Biol. 137, 377-386
26. Hamill, O. P., Marty, A., Neher, E., Sakmann, B., and Sigworth, F. J. (1981) Pfluegers Arch. 391, 85-100
27. Laemmli, U. K. (1970) Nature 227, 680-685
28. Brix, J., Rudiger, S., Bukau, B., Schneider-Mergener, J., and Pfanner, N. (1999) J. Biol. Chem. 274, 16522-16530
29. Martínez-Caballero, S., Peixoto, P. M. V., Kinnally, K. W., and Campo, M. L. (2007) Anal. Biochem. 362, 76-82
30. Lohret, T. A., and Kinnally, K. W. (1995) J. Biol. Chem. 270, 15950-15953
31. Lohret, T. A., and Kinnally, K. W. (1995) Biophys. J. 68, 2299-2309
32. Sirrenberg, C., Endres, M., Becker, K., Bauer, M. F., Walther, E., Neupert, W., and Brunner, M. (1997) J. Biol. Chem. 272, 29963-29966
33. Truscott, K. N., Kovermann, P., Geissler, A., Merlin, A., Meijer, M., Driessen, A. J., Pfanner, N., and Wagner, R. (2001) Nat. Struct. Biol. 8, 1074-1082
34. Ahting, U., Thieffry, M., Engelhardt, H., Hegerl, R., Neupert, W., and Nussberger, S. (2001) J. Cell Biol. 153, 1151-1160
35. Becker, L., Bannwarth, M., Meisinger, C., Hill, K., Model, K., Krimmer, T., Casadio, R., Truscott, K. N., Schulz, G. E., Pfanner, N., and Wagner, R. (2005) J. Mol. Biol. 353, 1011-1020
36. Decker, G. L., and Greenawalt, J. W. (1977) J. Ultrastruct. Res. 59, 44-56
37. Campo, M. L., and Tedeschi, H. (1984) Eur. J. Biochem. 141, 5-7
38. Kubrich, M., Rassow, J., Voos, W., Pfanner, N., and Honlinger, A. (1998) J. Biol. Chem. 273, 16374-16381
39. Kushnareva, Y. E., Campo, M. L., Kinnally, K. W., and Sokolove, P. M. (1999) Arch. Biochem. Biophys. 366, 107-115
40. Meinecke, M., Wagner, R., Kovermann, P., Guiard, B., Mick, D. U., Hutu, D. P., Voos, W., Truscott, K. N., Chacinska, A., Pfanner, N., and Rehling, P. (2006) Science 312, 1523-1526
41. Hille, B. (2002) Ionic Channels of Excitable Membranes, 4th Ed., pp. 351-354, Sinuaer Associates Inc., Sunderland, Massachusetts
42. Herrmann, J. M., and Hell, K. (2005) Trends Biochem. Sci. 30, 205-212
43. Frey, T. G., Renken, C. W., and Perkins, G. A. (2002) Biochim. Biophys. Acta Bioenerg. 1555, 196-203
44. Frey, T. G., and Mannella, C. A. (2000) Trends Biochem. Sci. 25, 319-324