Neurological phenotype and reduced lifespan in heterozygous Tim23 knockout mice, the first mouse model of defective mitochondrial import

Biochimica et Biophysica Acta - Bioenergetics

Volumn 1787, Issue 5, 2009, Pages 371-376

  Ahting, Uwe ^a   Floss, Thomas ^a   Uez, Nikolas ^a   Schneider Lohmar, Ilka ^a,b   Becker, Lore ^a,b   Kling, Eva ^a,b   Iuso, Arcangela ^a   Bender, Andreas ^b   de Angelis, Martin Hrabé ^a   Gailus Durner, Valérie ^a   Fuchs, Helmut ^a   Meitinger, Thomas ^a,c   Wurst, Wolfgang ^a   Prokisch, Holger ^a,c   Klopstock, Thomas ^a,b  

^a INSTITUTE OF EPIDEMIOLOGY   (Germany)

^b LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^c TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

DDP1; Mitochondrial import machinery; Tim23 knockout mouse

Indexed keywords

MITOCHONDRIAL PROTEIN; PROTEIN TIM23; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; EMBRYO; EMBRYONIC STEM CELL; GENE MUTATION; HETEROZYGOSITY; KNOCKOUT MOUSE; LIFESPAN; MITOCHONDRIAL MEMBRANE; MOHR TRANEBJAERG SYNDROME; MOUSE; NEUROLOGIC DISEASE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN TRANSPORT; SYNDROME;

ANIMALS; BLASTOCYST; FORELIMB; GENOTYPE; HAND STRENGTH; HUMANS; LIFE EXPECTANCY; MEMBRANE PROTEINS; MEMBRANE TRANSPORT PROTEINS; MICE; MICE, KNOCKOUT; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; MUTATION; OROFACIODIGITAL SYNDROMES; PHENOTYPE; PROTEIN TRANSPORT; ROTAROD PERFORMANCE TEST;

MUS;

EID: 67349202202     PISSN: 00052728     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbabio.2008.12.001     Document Type: Article

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