Enhanced transforming growth factor-β signaling and fibrogenesis in ovine fetal skeletal muscle of obese dams at late gestation

American Journal of Physiology - Endocrinology and Metabolism

Volumn 298, Issue 6, 2010, Pages

  Huang, Yan ^a   Yan, Xu ^a   Zhu, Mei J ^a   McCormick, Richard J ^a   Ford, Stephen P ^a   Nathanielsz, Peter W ^b   Du, Min ^a  

^a UNIVERSITY OF WYOMING   (United States)

^b UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

Author keywords

Collagen; Fetus; Maternal obesity

Indexed keywords

COLLAGEN; FIBRONECTIN; MITOGEN ACTIVATED PROTEIN KINASE P38; PROCOLLAGEN LYSINE 2 OXOGLUTARATE 5 DIOXYGENASE; PROCOLLAGEN LYSINE 2 OXOGLUTARATE 5 DIOXYGENASE 2B; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE ALPHA1; PROTEIN LYSINE 6 OXIDASE; SMAD7 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; FETUS; FIBROGENESIS; GESTATIONAL AGE; MATERNAL DISEASE; MYOFIBROSIS; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEMITENDINOUS MUSCLE; SHEEP; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; UPREGULATION;

ANIMALS; BLOTTING, WESTERN; COLLAGEN TYPE I; ELECTROPHORETIC MOBILITY SHIFT ASSAY; FEMALE; FETUS; FIBRONECTINS; LINEAR MODELS; MALE; MUSCLE FIBERS, SKELETAL; OBESITY; PREGNANCY; PROCOLLAGEN-LYSINE, 2-OXOGLUTARATE 5-DIOXYGENASE; PROCOLLAGEN-PROLINE DIOXYGENASE; PROTEIN-LYSINE 6-OXIDASE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SHEEP; SIGNAL TRANSDUCTION; SMAD7 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; TUBULIN;

EID: 77952647419     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00015.2010     Document Type: Article

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