Time-dependent and tissue-specific effects of circulating glucose on fetal ovine glucose transporters

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 276, Issue 3 45-3, 1999, Pages

  Das, Utpala G ^a   Schroeder, Robert E ^b   Hay Jr , William W ^c   Devaskar, Sherin U ^a,d  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b Health Sciences Center   (United States)

^c University of Colorado ^*  (United States)

^d Dept of Pediatrics ^*  (United States)

Author keywords

Fetal hyperglycemia; Fetal hypoglycemia; Maternal diabetes; Maternal hyperglycemia; Maternal hypoglycemia

Indexed keywords

GLUCOSE TRANSPORTER; INSULIN;

ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; FEMALE; FETUS; GESTATIONAL AGE; GLUCOSE BLOOD LEVEL; GLUCOSE TRANSPORT; HYPERGLYCEMIA; HYPOGLYCEMIA; INSULIN BLOOD LEVEL; MATERNAL DIABETES MELLITUS; NONHUMAN; PRIORITY JOURNAL; SHEEP; TISSUE SPECIFICITY;

EID: 0032896761     PISSN: 03636119     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpregu.1999.276.3.r809     Document Type: Article

References (44)

1. Bell, G. I., C. F. Burant, J. Takeda, and G. W. Gould. Structure and function of mammalian facilitative sugar transporters. J. Biol. Chem. 268: 19161-19164, 1993.
2. Birnbaum, M. J. Identification of a novel gene encoding an insulin-responsive glucose transporter protein. Cell 57: 305-315, 1989.
3. Bloch, C. A., W. Banach, K. Landt, S. Devaskar, and M. A. Sperling. Effects of fetal insulin infusion on glucose kinetics in pregnant sheep: a compartmental analysis. Am. J. Physiol. 251 (Endocrinol. Metab. 14): E448-E456, 1986.
4. Boubon, J., and M. Gilbert. Role of fetal insulin in glycogen metabolism in the liver of the rat fetus. Biol. Neonate 40: 38-45, 1981.
5. Bristow, J., A. M. Rudolph, and J. Itskovitz. A preparation for studying liver blood flow, oxygen consumption, and metabolism in the fetal lamb in utero. J. Dev. Physiol. 3: 255-266, 1981.
6. Camps, M., A. Castello, P. Munoz, M. Monfar, X. Testar, M. Palaica, and A. Zorzano. Effect of diabetes and fasting on GLUT 4 (muscle/fat) glucose transporter expression in insulin-sensitive tissues. Biochem. J. 282: 765-772, 1992.
7. Carver, T. D., S. M. Anderson, P. A. Aldoretta, A. L. Esler, and W. W. Hay, Jr. Glucose suppression of insulin secretion in chronically hyperglycemic fetal sheep. Pediatr. Res. 38: 754-762. 1995.
8. 2 consumption after long-term hypoglycemia in pregnant sheep. Am. J. Physiol. 269 (Endocrinol. Metab. 32): E299-E308, 1995.
9. Charron, M. J., and B. B. Kahn. Divergent molecular mechanisms for insulin-resistant glucose transport in muscle and adipose cells in vivo. J. Biol. Chem. 265: 7994-8000, 1990.
10. Christie, W. W., and R. C. Noble. Fatty acid synthesis in sheep placenta and maternal and fetal adipose tissue. Biol. Neonate 42: 79-86, 1982.
11. Devaskar, S. U., U. P. Devaskar, R. E. Schroeder, D. E. deMello, F. T. Fiedorek, Jr., and M. Mueckler. Expression of genes involved in placental glucose uptake and transport in the nonobese diabetic mouse pregnancy. Am. J. Obstet. Gynecol. 171: 1316-1323, 1994.
12. Devaskar, S. U., and M. Mueckler. The mammalian glucose transporters. Pediatr. Res. 31: 1-12, 1992.
13. DiGiacomo, J. E., and W. W. Hay, Jr. Fetal glucose metabolism and oxygen consumption during sustained hypoglycemia. Metabolism 39: 193-202, 1990.
14. Ehrhardt, R. A., and A. W. Bell. Developmental increases in glucose transporter concentration in the sheep placenta. Am. J. Physiol. 273 (Regulatory Integrative Comp. Physiol. 42): R1132-R1141, 1997.
15. Garvey, W. T., T. P. Huecksteadt, and M. J. Birnbaum. Pretranslational suppression of an insulin-responsive glucose transporter in rats with diabetes mellitus. Science 245: 60-63, 1989.
16. Garvey, W. T., L. Maianu, T. P. Huecksteadt, M. J. Birnbaum, J. M. Molina, and T. P. Ciaraldi. Pretranslational suppression of a glucose transporter protein causes insulin resistance in adipocytes from patients with non-insulin-dependent diabetes mellitus and obesity. J. Clin. Invest. 87: 1072-1081, 1991.
17. Gould, G. W., H. M. Thomas, T. J. Jess, and G. I. Bell. Expression of human glucose transporters in Xenopus oocytes: kinetic characterization and substrate specificities of the erythrocyte, liver, and brain isoforms. Biochemistry 30: 5139-5145, 1991.
18. Hay, Jr., W. W., and H. K. Meznarich. The effect of hyperinsulinemia on glucose utilization and oxidation and on oxygen consumption in the fetal lamb. J. Exp. Psychol. 71: 689-698, 1986.
19. Hay, Jr., W. W., H. K. Meznarich, J. E. DiGiacomo, K. Hirst, and G. Zerbe. Effects of insulin and glucose concentrations on glucose utilization in fetal sheep. Pediatr. Res. 23: 381-387, 1988.
20. Hiraki, Y., O. M. Rosen, and M. J. Birnbaum. Growth factors rapidly induce expression of the glucose transporter gene. J. Biol. Chem. 263: 13655-13662, 1988.
21. James, D. E., M. Strube, and M. Mueckler. Molecular cloning and characterization of an insulin-regulatable glucose transporter. Nature 338: 83-87, 1989.
22. Jetton, T. L., and M. A. Magnuson. Heterogenous expression of glucokinase among pancreatic beta cells. Proc. Natl. Acad. Sci. USA 89: 2619-2623, 1992.
23. Kahn, B. B., I. A. Simpson, and S. W. Cushman. Divergent mechanisms for the insulin resistant and hyperresponsive glucose transport in adipose cells from fasted and refed rats. J. Clin. Invest. 82: 691-699, 1988.
24. Kraegen, E. W., J. A. Sowden, M. B. Halstead, P. W. Clark, K. J. Rodnick, D. J. Chisholm, and D. E. James. Glucose transporters and in vivo glucose uptake in skeletal and cardiac muscle: fasting, insulin stimulation and immunoisolation studies of GLUT1 and GLUT4. Biochem. J. 295: 287-293, 1993.
25. Leturque, A., C. Postic, P. Ferre, and J. Girard. Nutritional regulation of glucose transporter in muscle and adipose tissue of weaned rats. Am. J. Physiol. 260 (Endocrinol. Metab. 23): E588-E593, 1991.
26. Maeda, Y., S. Akazawa, M. Akazawa, Y. Takao, K. A. Trocino, H. Takino, E. Kawasaki, A. Yokota, S. Okuno, and S. Nagataki. Glucose transporter gene expression in rat conceptus during early organogenesis and exposure to insulin-induced hypoglycemic serum. Acta Diabetol. 30: 1-6, 1993.
27. Mantych, G., D. E. James, H. D. Chung, and S. Devaskar. Cellular localization and characterization of Glut 3 glucose transporter isoform in human brain. Endocrinology 131: 1270-1278, 1992.
28. Nagamatsu, S., H. Sawa, N. Inoue, Y. Nakamichi, H. Takeshima, and T. Hoshino. Gene expression of GLUT3 glucose transporter regulated by glucose in vivo in mouse brain and in vitro in neuronal cell cultures from rat embryos. Biochem. J. 300: 125-131, 1994.
29. Postic, C.,A. Leturque, R. L. Printz, P. Maulard, M. Loizeau, D. K. Granner, and J. Girard. Development and regulation of glucose transporter and hexokinase expression in rat. Am. J. Physiol. 266 (Endocrinol. Metab. 29): E548-E559, 1994.
30. Rodnick, K. J., J. W. Slot, D. R. Studelska, D. E. Hanpeter, L. J. Robinson, H. J. Geuze, and D. E. James. Immunocytochemical and biochemical studies of GLUT4 in rat skeletal muscle. J. Biol. Chem. 267: 6278-6285, 1992.
31. Sadiq, H. F., D. E. deMello, and S. U. Devaskar. The effect of intrauterine growth restriction upon fetal and postnatal hepatic glucose transporter and glucokinase proteins. Pediatr. Res. 43: 91-100, 1997.
32. Santalucia, T., M. Camps, A. Castello, P. Munoz, A. Nuel, X. Testar, M. Palacin, and A. Zorzano. Developmental regulation of GLUT-1 (erythroid/Hep G2) and GLUT-4 (muscle/fat) glucose transporter expression in the rat heart, skeletal muscle, and brown adipose tissue. Endocrinology 130: 837-846, 1992.
33. Schroeder, R. E., U. P. Devaskar, S. E. Trail, D. E. deMello, D. P. Cole, and S. U. Devaskar. Effect of maternal diabetes on the expression of genes regulating fetal brain glucose uptake. Diabetes 42: 1487-1497, 1993.
34. Schroeder, R. E., C. L. Doria-Medina, U. G. Das, W. I. Sivitz, and S. U. Devaskar. Effect of maternal diabetes upon fetal rat myocardial and skeletal muscle glucose transporters. Pediatr. Res. 41: 11-19, 1997.
35. Schroeder, R. E., P. A. Rajakumar, and S. U. Devaskar. Effect of streptozotocin-induced maternal diabetes on fetal rat brain glucose transporters. Pediatr. Res. 41: 346-352, 1997.
36. Simmons, R. A., A. S. Flozak, and E. S. Ogata. The effect of insulin and insulin-like growth factor-1 on glucose transport in normal and small for gestational age fetal rats. Endocrinology 259: 1361-1368, 1993.
37. Simmons, R. A., A. S. Gounis, S. E. Bangalore, and E. S. Ogata. Intrauterine growth retardation: fetal glucose transport is diminished in lung but spared in brain. Pediatr. Res. 121: 1366-1372, 1987.
38. Uehara, Y., V. Nipper, A. L. McCall. Chronic insulin hypoglycemia induces GLUT-3 protein in rat brain neurons. Am. J. Physiol. 272 (Endocrinol. Metab. 35): E716-E719, 1997.
39. Vannucci, S. J. Developmental expression of GLUT1 and GLUT3 glucose transporters in rat brain. J. Neurochem. 62: 240-246, 1994.
40. Vannucci, S. J., F. Maher, E. Koehler, I. A. Simpson. Altered expression of GLUT-1 and GLUT-3 glucose transporters in neurohypophysis of water-deprived or diabetic rats. Am. J. Physiol. 267 (Endocrinol. Metab. 30): E605-E611, 1994.
41. Wang, W., P. A. Hansen, B. A. Marshall, J. O. Holloszy, and M. Mueckler. Insulin unmasks a COOH-terminal Glut4 epitope and increases glucose transport across T-tubules in skeletal muscle. J. Cell Biol. 135: 415-430, 1996.
42. Werner, H., M. Adamo, W. L. Lowe, Jr., C. T. Roberts, Jr., and D. LeRoith. Developmental regulation of the rat brain/Hep G2 glucose transporter gene expression. Mol. Endocrinol. 3: 273-279, 1989.
43. Wilkening, R. B., D. W. Boyle, C. Teng, G. Meschia, and F. C. Battaglia. Amino acid uptake by the fetal ovine hindlimb under normal and euglycemic hyperinsulinemia states. Am. J. Physiol. 266 (Endocrinol. Metab. 29): E72-E78, 1994.
44. Yki-Jarvinen, H. Glucose toxicity. Endocr. Rev. 13: 147-163, 1992.