A yeast TDP-43 proteinopathy model: Exploring the molecular determinants of TDP-43 aggregation and cellular toxicity

Proceedings of the National Academy of Sciences of the United States of America

Volumn 105, Issue 17, 2008, Pages 6439-6444

  Johnson, Brian S ^a   McCaffery, J Michael ^b   Lindquist, Susan ^c   Gitler, Aaron D ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

^c WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

Author keywords

Amyotrophic lateral sclerosis; Frontal temporal dementia; Saccharomyces cerevisiae; TAR DNA binding protein

Indexed keywords

DNA BINDING PROTEIN; POLYGLUTAMINE; PROTEIN TDP 43; AMYLOID; PEPTIDE; PROTEIN TDP-43;

AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; CELLULAR DISTRIBUTION; CYTOPLASM; CYTOTOXICITY; DEMENTIA; FRONTAL TEMPORAL DEMENTIA; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN FOLDING; PROTEIN LOCALIZATION; YEAST CELL; BIOLOGICAL MODEL; CELL INCLUSION; CELL NUCLEUS; CHEMISTRY; CYTOLOGY; METABOLISM; PROTEIN QUATERNARY STRUCTURE; PROTEIN TRANSPORT; SACCHAROMYCES CEREVISIAE;

SACCHAROMYCES CEREVISIAE;

AMYLOID; CELL NUCLEUS; DNA-BINDING PROTEINS; INCLUSION BODIES; MODELS, BIOLOGICAL; PEPTIDES; PROTEIN STRUCTURE, QUATERNARY; PROTEIN TRANSPORT; SACCHAROMYCES CEREVISIAE;

EID: 44049097065     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0802082105     Document Type: Article

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