Binding of inositol 1,4,5-trisphosphate (IP3) and adenophostin A to the N-Terminal region of the IP3 receptor: Thermodynamic analysis using fluorescence polarization with a novel IP3 receptor ligand

Molecular Pharmacology

Volumn 77, Issue 6, 2010, Pages 995-1004

  Ding, Zhao ^a   Rossi, Ana M ^a   Riley, Andrew M ^b   Rahman, Taufiq ^a   Potter, Barry V L ^b   Taylor, Colin W ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b University of Bath   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOPHOSTIN A; CALCIUM CHANNEL; FLUORESCEIN ISOTHIOCYANATE; INOSITOL 1,4,5 TRISPHOSPHATE; INOSITOL 1,4,5 TRISPHOSPHATE RECEPTOR; LIGAND; PARTIAL AGONIST;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; CALCIUM CELL LEVEL; CONFORMATIONAL TRANSITION; CYTOSOL; DRUG RECEPTOR BINDING; ENTROPY; FLUORESCENCE POLARIZATION; LIGAND BINDING; PRIORITY JOURNAL; RECEPTOR UPREGULATION; TEMPERATURE SENSITIVITY; THERMODYNAMICS;

ADENOSINE; ANIMALS; FLUORESCEIN-5-ISOTHIOCYANATE; FLUORESCENCE POLARIZATION; INOSITOL 1,4,5-TRISPHOSPHATE; INOSITOL 1,4,5-TRISPHOSPHATE RECEPTORS; LIGANDS; PROTEIN BINDING; RATS; THERMODYNAMICS;

EID: 77952356661     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.109.062596     Document Type: Article

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