Ligand-induced Conformational Changes via Flexible Linkers in the Amino-terminal region of the Inositol 1,4,5-Trisphosphate Receptor

Journal of Molecular Biology

Volumn 373, Issue 5, 2007, Pages 1269-1280

  Chan, Jenny ^a   Whitten, Andrew E ^b,c   Jeffries, Cy M ^c   Bosanac, Ivan ^a   Mal, Tapas K ^a   Ito, Jennifer ^a   Porumb, Horea ^d   Michikawa, Takayuki ^e,f,g   Mikoshiba, Katsuhiko ^e,f,g   Trewhella, Jill ^c   Ikura, Mitsuhiko ^a  

^a PRINCESS MARGARET HOSPITAL   (Canada)

^b AUSTRALIAN NUCLEAR SCIENCE AND TECHNOLOGY ORGANISATION   (Australia)

^c UNIVERSITY OF SYDNEY   (Australia)

^d INSTITUT GUSTAVE ROUSSY   (France)

^e THE UNIVERSITY OF TOKYO   (Japan)

^f RIKEN BRAIN SCIENCE INSTITUTE   (Japan)

^g JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

circular dichroism; conformational variability; modeling; NMR; small angle X ray scattering

Indexed keywords

CALCIUM CHANNEL; CALCIUM ION; INOSITOL 1,4,5 TRISPHOSPHATE RECEPTOR; LIGAND;

AMINO TERMINAL SEQUENCE; ARTICLE; CALCIUM SIGNALING; CIRCULAR DICHROISM; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; LIGAND BINDING; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DENATURATION; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN SECONDARY STRUCTURE; PROTEIN STABILITY; X RAY CRYSTALLOGRAPHY;

EID: 35148829933     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2007.08.057     Document Type: Article

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