Cholesterol 7α-hydroxylase (CYP7A1) activity is modified after chronic ingestion of depleted uranium in the rat

Journal of Steroid Biochemistry and Molecular Biology

Volumn 120, Issue 1, 2010, Pages 60-66

  Racine, R ^a   Grandcolas, L ^a   Grison, S ^a   Stefani, J ^a   Delissen, O ^a   Gourmelon, P ^a   Veyssiere G ^b   Souidi, M ^a  

^a INSTITUT DE RADIOPROTECTION ET DE SÛRETÉ NUCLÉAIRE IRSN   (France)

^b UNIVERSITÉ CLERMONT AUVERGNE   (France)

Author keywords

Cholesterol metabolism; Chronic contamination; Cytochrome P450; Depleted uranium; Liver; Oxysterol

Indexed keywords

7ALPHA HYDROXYCHOLESTEROL; ABC TRANSPORTER; ABC TRANSPORTER A1; ABC TRANSPORTER G5; ABC TRANSPORTER G8; BILE ACID; CHOLESTEROL; CHOLESTEROL 7ALPHA MONOOXYGENASE; CHOLESTEROL ESTER; CYTOCHROME P450; CYTOCHROME P450 7B1; DRINKING WATER; RETINOID X RECEPTOR; UNCLASSIFIED DRUG; URANIUM; CHOLESTANETRIOL 26 MONOOXYGENASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CATABOLISM; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL METABOLISM; CHOLESTEROL SYNTHESIS; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; ENZYME ACTIVITY; GENE EXPRESSION REGULATION; HYPERCHOLESTEROLEMIA; INGESTION; LIVER METABOLISM; LONG TERM EXPOSURE; MALE; MODULATION; NONHUMAN; NUCLEOTIDE SEQUENCE; RAT; TRANSCRIPTION REGULATION; WATER CONTAMINATION; ANIMAL; DRUG EFFECT; ENZYMOLOGY; GENETICS; LIVER; METABOLISM; SPRAGUE DAWLEY RAT; TIME;

RATTUS;

ANIMALS; CHOLESTEROL; CYTOCHROME P-450 CYP27A1; LIVER; MALE; RATS; RATS, SPRAGUE-DAWLEY; TIME FACTORS; URANIUM;

EID: 77952307986     PISSN: 09600760     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jsbmb.2010.03.066     Document Type: Article

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