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Saltz L, Rubin M, Hochster H, Tchekmeydian NS, Waksal H, Needle M, LoBuglio A. Cetuximab (IMC-C225) plus irinotecan (CPT-11) is active in CPT-11 refractory colorectal cancer (CRC) that expresses epidermal growth factor rector (EGFR). Proc Am Soc Clin Oncol 2001; 20: 7 (Abstract)
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MABEL. A large multinational study of cetuximab plus irinotecan in irinotecan resistant metastatic colorectal cancer
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Wilke H, Glynne-Jones R, Thaler J, Adenis A, Preusser P, Aranda Aguilar A, Aapro M, Van Den Berg N, Eggleton S, Siena S. MABEL. A large multinational study of cetuximab plus irinotecan in irinotecan resistant metastatic colorectal cancer. Proc Am Soc Clin Oncol 2006; 158s: 3549 (Abstract)
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Abubakr Y, Eng C, Wong L, Pautret V, Scheithauer W, Maurel J, Kroening H, lutz M, Zubel A, Sobrero A. Cetuximab plus irinotecan for metastatic colorectal cancer: Safety analysis of 800 patients in a randomized phase III trial. Proc Am Soc Clin Oncol 2006; 160s: 3556 (Abstract)
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Abubakr Y, Eng C, Wong L, Pautret V, Scheithauer W, Maurel J, Kroening H, lutz M, Zubel A, Sobrero A. Cetuximab plus irinotecan for metastatic colorectal cancer: Safety analysis of 800 patients in a randomized phase III trial. Proc Am Soc Clin Oncol 2006; 160s: 3556 (Abstract)
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10
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Vincenzi B, Santini D, Tonini G. Lack of response of cetuximab plus oxaliplatin in advanced colorectal cancer patients resistant to both oxaliplatin and cetuximab plus irinotecan. Ann Oncol 2006; 17: 527-528
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Vincenzi B, Santini D, Rabitti C, Coppola R, Beomonte Zobel B, Trodella L, Tonini G. Cetuximab and irinotecan as third-line therapy in advanced colorectal cancer patients: a single centre phase II trial. Br J Cancer 2006; 94: 792-797
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36348947822
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Smith DM, Legoux J, Brunet R, Adhoute X, Blanc J, Fonck M, Vendrely V, Becouarn Y. Cetuximab in combination with FOLFIRI in second and third line treatment of metastaic colorectal cancer: Safety and efficacy analysis. Proc Am Soc Clin Oncol 2006; 160s: 3558 (Abstract)
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33750905700
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Venook A, Niedzwiecki D, Hollis D, Sutherland S, Goldberg R, Alberts S, benson A, Wade J, Schilsky R, Mayer R. Phase III study of FOLFIRI or FOLFOX with or without cetuximab for patients with untreated metastatic adenocarcinoma of the colon or rectum: CALGB 80203 preliminary results. Proc Am Soc Clin Oncol 2006; 148s: 3509 (Abstract)
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33749840555
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Heinemann V, Fischer Von Weikersthal L, Moosmann N, Vehling-Kaiser U, Stauch M, Oruzio D, Schulze M, Walther J, Weiss J, Dietzfelbinger H. Cetuximab + capecitabine + irinotecan versus cetuximab + capecitabine + oxaliplatin as first line therapy for patients with metastatic colorectal cancer: Preliminary results of a randomized phase II trial of the AIO CRC Study Group. Proc Am Soc Clin Oncol 2006; 158s: 3550 (Abstract)
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Cetuximab and irinotecan/5-fluorouracil/folinic acid is a safe combination for the first-line treatment of patients with epidermal growth factor receptor expressing metastatic colorectal carcinoma
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Folprecht G, Lutz MP, Schoffski P, Seufferlein T, Nolting A, Pollert P, Kohne CH. Cetuximab and irinotecan/5-fluorouracil/folinic acid is a safe combination for the first-line treatment of patients with epidermal growth factor receptor expressing metastatic colorectal carcinoma. Ann Oncol 2006; 17: 450-456
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Dakhil S, Cosgriff T, Headley D, Boccia RV, Badarinath S. Cetuximab plus FOLFOX-6 as first line therapy for metastatic colorectal cancer. (An International Oncology Network study, I-03-002.). Proc Am Soc Clin Oncol 2006; 160s: 3557 (Abstract)
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Colucci G, Giuliani F, Mattioh R, Garufi C, Mallamaci R, Pezella G, Lopz M, Maiello E. FOLFOX-4 plus cetuximab in untreated patients with advanced colorectal cancer. A phase II study of the Gruppo Oncologico dell'Italia Meridionale (prot GOIM 2402. Proc Am Soc Clin Oncol 2006; 160s: 3559 (Abstract)
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Bokemeyer C, Bondarenko I, Makhson A, Hartmann JT, Aparicio J, Zampino M, Donea S, Ludwig H, Zubel A, Koralewski P. Cetuximab plus FOLFOX versus FOLFOX4 in the first line treatment of metastatic colorectal cancer: OPUS, a randomized phase II study. Proc Am Soc Clin Oncol 2007; 172s: 4035 (Abstract)
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Van Cutsem E, Nowacki M, Lang I, Cascinu S, Shchepotin I, Maurel J, Rougier P, Cunningham D, Nippgen J, Kohne C. Randomized phase III study of FOLRIRI with or without Cetuximab in the first line treatment of patients with metastatic colorectal cancer: The CRYSTAL trial. Proc Am Soc Clin Oncol 2007; 164s: 4000 (Abstract)
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Teipar S, Peeters M, Humblet Y, Gelderblom H, Vermorken J, Viret F, Glimelius F, Ciardiello F, Kisker O, Van Cutsem E. Phase I/II study of cetuximab dose escalation in patients with metastatic colorectal cancer with no or slight skin reactions on cetuximab standard dose treatment (EVEREST study). Pharmacokinetic, Pharmacodynamic and efficacy data. Proc Am Soc Clin Oncol 2007; 172s: 4037 (Abstract)
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Epidermal growth factor gene amplification is not frequent and cannot account for antitumor activity of cetuximab plus chemotherapy in advanced colorectal cancer patients
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Garufi C, Mottolese M, Cianciulli A, Zeuli M, Buglioni S, Torsello A, Vanni B, Campanellaa C, Merola R, Terzoli E. Epidermal growth factor gene amplification is not frequent and cannot account for antitumor activity of cetuximab plus chemotherapy in advanced colorectal cancer patients. Proc Am Soc Clin Oncol 2006; 161s: 3561 (Abstract)
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25
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K-ras mutation is highly predictive of cetuximab resistance in metastatic colorectal cancer
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Association of cychn D1 (CCND1) gene A870G polymorphism and clinical outcome of EGFR-positive metastatic colorectal cancer patients treated with epidermal growth factor receptor (EGFR) inhibitor cetuximab (C225)
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Zhang W, Yun J, Press CIA, Gordon M, Yang DY, Mallik N, Sherrod A, Iqbal S, Lenz HJ. Association of cychn D1 (CCND1) gene A870G polymorphism and clinical outcome of EGFR-positive metastatic colorectal cancer patients treated with epidermal growth factor receptor (EGFR) inhibitor cetuximab (C225). Proc Am Soc Clin Oncol 2004: 3518 (Abstract)
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