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Volumn 3, Issue 5-6, 2010, Pages 268-273

Idiopathic pulmonary arterial hypertension

Author keywords

[No Author keywords available]

Indexed keywords

7,8 DIHYDRO 5 [2 [[ALPHA (3 PYRIDYL)BENZYLIDENE]AMINOOXY]ETHYL] 1 NAPHTHYLOXYACETIC ACID; AMLODIPINE; ATORVASTATIN; BOSENTAN; CYCLO(DEXTRO TRYPTOPHYL DEXTRO ASPARTYLPROLYL DEXTRO VALYLLEUCYL); HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; ILOPROST; MONOCROTALINE; NIFEDIPINE; PROSTACYCLIN; SILDENAFIL; SIMVASTATIN; UNIPROST;

EID: 77952192354     PISSN: 17548403     EISSN: 17548411     Source Type: Journal    
DOI: 10.1242/dmm.003616     Document Type: Article
Times cited : (51)

References (55)
  • 3
    • 0035844211 scopus 로고    scopus 로고
    • Hypoxia-induced Proliferative Response of Vascular Adventitial Fibroblasts is Dependent on G Protein-mediated Activation of Mitogen-activated Protein Kinases
    • DOI 10.1074/jbc.M010690200
    • Das, M., Bouchey, D. M., Moore, M. J., Hopkins, D. C., Nemenoff, R. A. and Stenmark, K. R. (2001). Hypoxia-induced proliferative response of vascular adventitial fibroblasts is dependent on G protein-mediated activation of mitogen-activated protein kinases. J. Biol. Chem. 276, 15631-15640. (Pubitemid 37391590)
    • (2001) Journal of Biological Chemistry , vol.276 , Issue.19 , pp. 15631-15640
    • Das, M.1    Bouchey, D.M.2    Moore, M.J.3    Hopkins, D.C.4    Nemenoff, R.A.5    Stenmark, K.R.6
  • 4
    • 0025785692 scopus 로고
    • ATP-dependent potassium channels of muscle cells: Their properties, regulation, and possible functions
    • Davies, N. W., Standen, N. B. and Stanfield, P. R. (1991). ATP-dependent potassium channels of muscle cells: their properties, regulation, and possible functions. J. Bioenerg. Biomembr. 23, 509-535.
    • (1991) J. Bioenerg. Biomembr. , vol.23 , pp. 509-535
    • Davies, N.W.1    Standen, N.B.2    Stanfield, P.R.3
  • 5
    • 70049112901 scopus 로고    scopus 로고
    • Guidelines for the diagnosis and treatment of pulmonary hypertension: The task force for the diagnosis and treatment of pulmonary hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS), endorsed by the International Society of Heart and Lung Transplantation (ISHLT)
    • Galie, N., Hoeper, M. M., Humbert, M., Torbicki, A., Vachiery, J. L., Barbera, J. A., Beghetti, M., Corris, P., Gaine, S., Gibbs, J. S. et al. (2009). Guidelines for the diagnosis and treatment of pulmonary hypertension: the task force for the diagnosis and treatment of pulmonary hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS), endorsed by the International Society of Heart and Lung Transplantation (ISHLT). Eur. Heart J. 30, 2493-2537.
    • (2009) Eur. Heart J. , vol.30 , pp. 2493-2537
    • Galie, N.1    Hoeper, M.M.2    Humbert, M.3    Torbicki, A.4    Vachiery, J.L.5    Barbera, J.A.6    Beghetti, M.7    Corris, P.8    Gaine, S.9    Gibbs, J.S.10
  • 6
    • 0031690521 scopus 로고    scopus 로고
    • Nitric oxide and endothelin-1 in pulmonary hypertension
    • Giaid, A. (1998). Nitric oxide and endothelin-1 in pulmonary hypertension. Chest 114, 208S-212S.
    • (1998) Chest , vol.114
    • Giaid, A.1
  • 9
    • 1542784420 scopus 로고    scopus 로고
    • S100A4/Mts1 Produces Murine Pulmonary Artery Changes Resembling Plexogenic Arteriopathy and Is Increased in Human Plexogenic Arteriopathy
    • Greenway, S., van Suylen, R. J., Du Marchie Sarvaas, G., Kwan, E., Ambartsumian, N., Lukanidin, E. and Rabinovitch, M. (2004). S100A4/Mts1 produces murine pulmonary artery changes resembling plexogenic arteriopathy and is increased in human plexogenic arteriopathy. Am. J. Pathol. 164, 253-262. (Pubitemid 38364609)
    • (2004) American Journal of Pathology , vol.164 , Issue.1 , pp. 253-262
    • Greenway, S.1    Van Suylen, R.J.2    Sarvaas, G.D.M.3    Kwan, E.4    Ambartsumian, N.5    Lukanidin, E.6    Rabinovitch, M.7
  • 10
    • 0035176720 scopus 로고    scopus 로고
    • Vascular remodeling in experimentally induced subacute canine pulmonary hypertension
    • Gust, R. and Schuster, D. P. (2001). Vascular remodeling in experimentally induced subacute canine pulmonary hypertension. Exp. Lung Res. 27, 1-12. (Pubitemid 32056097)
    • (2001) Experimental Lung Research , vol.27 , Issue.1 , pp. 1-12
    • Gust, R.1    Schuster, D.P.2
  • 11
    • 41149115441 scopus 로고    scopus 로고
    • Enhancement of pulmonary vascular remodelling and inflammatory genes with VIP gene deletion
    • Hamidi, S. A., Prabhakar, S. and Said, S. I. (2008). Enhancement of pulmonary vascular remodelling and inflammatory genes with VIP gene deletion. Eur. Respir. J. 31, 135-139.
    • (2008) Eur. Respir. J. , vol.31 , pp. 135-139
    • Hamidi, S.A.1    Prabhakar, S.2    Said, S.I.3
  • 14
    • 20444434392 scopus 로고    scopus 로고
    • Development of occlusive neointimal lesions in distal pulmonary arteries of endothelin B receptor-deficient rats: A new model of severe pulmonary arterial hypertension
    • DOI 10.1161/CIRCULATIONAHA.104.491456
    • Ivy, D. D., McMurtry, I. F., Colvin, K., Imamura, M., Oka, M., Lee, D.-S., Gebb, S. and Jones, P. L. (2005). Development of occlusive neointimal lesions in distal pulmonary arteries of endothelin B receptor-deficient rats: a new model of severe pulmonary arterial hypertension. Circulation 111, 2988-2996. (Pubitemid 40814193)
    • (2005) Circulation , vol.111 , Issue.22 , pp. 2988-2996
    • Ivy, D.D.1    McMurtry, I.F.2    Colvin, K.3    Imamura, M.4    Oka, M.5    Lee, D.-S.6    Gebb, S.7    Jones, P.L.8
  • 17
    • 0033817459 scopus 로고    scopus 로고
    • Heterozygous germline mutations in BMPR2, encoding a TGF-β receptor, cause familial primary pulmonary hypertension
    • The IPPH Consortium
    • Lane, K. B., Machado, R. D., Pauciulo, M. W., Thomson, J. R., Phillips, J. A., III, Loyd, J. E., Nichols, W. C., Trembath, R. C. and The IPPH Consortium (2000). Heterozygous germline mutations in BMPR2, encoding a TGF-β receptor, cause familial primary pulmonary hypertension. Nat. Genet. 26, 81-84.
    • (2000) Nat. Genet. , vol.26 , pp. 81-84
    • Lane, K.B.1    Machado, R.D.2    Pauciulo, M.W.3    Thomson, J.R.4    Phillips III, J.A.5    Loyd, J.E.6    Nichols, W.C.7    Trembath, R.C.8
  • 18
    • 33745172176 scopus 로고    scopus 로고
    • Efficacy of long-term subcutaneous treprostinil sodium therapy in pulmonary hypertension
    • DOI 10.1378/chest.129.6.1636
    • Lang, I., Gomez-Sanchez, M., Kneussl, M., Naeije, R., Escribano, P., Skoro-Sajer, N. and Vachiery, J. L. (2006). Efficacy of long-term subcutaneous treprostinil sodium therapy in pulmonary hypertension. Chest 129, 1636-1643. (Pubitemid 43894997)
    • (2006) Chest , vol.129 , Issue.6 , pp. 1636-1643
    • Lang, I.1    Gomez-Sanchez, M.2    Kneussl, M.3    Naeije, R.4    Escribano, P.5    Skoro-Sajer, N.6    Vachiery, J.-L.7
  • 20
    • 61349100681 scopus 로고    scopus 로고
    • Altered bone morphogenetic protein and transforming growth factor-beta signaling in rat models of pulmonary hypertension: Potential for activin receptor-like kinase-5 inhibition in prevention and progression of disease
    • Long, L., Crosby, A., Yang, X., Southwood, M., Upton, P. D., Kim, D. K. and Morrell, N. W. (2009). Altered bone morphogenetic protein and transforming growth factor-beta signaling in rat models of pulmonary hypertension: potential for activin receptor-like kinase-5 inhibition in prevention and progression of disease. Circulation 119, 566-576.
    • (2009) Circulation , vol.119 , pp. 566-576
    • Long, L.1    Crosby, A.2    Yang, X.3    Southwood, M.4    Upton, P.D.5    Kim, D.K.6    Morrell, N.W.7
  • 26
    • 0141730236 scopus 로고    scopus 로고
    • Simvastatin rescues rats from fatal pulmonary hypertension by inducing apoptosis of neointimal smooth muscle cells
    • DOI 10.1161/01.CIR.0000087592.47401.37
    • Nishimura, T., Vaszar, L. T., Faul, J. L., Zhao, G., Berry, G. J., Shi, L., Qiu, D., Benson, G., Pearl, R. G. and Kao, P. N. (2003). Simvastatin rescues rats from fatal pulmonary hypertension by inducing apoptosis of neointimal smooth muscle cells. Circulation 108, 1640-1645. (Pubitemid 37187793)
    • (2003) Circulation , vol.108 , Issue.13 , pp. 1640-1645
    • Nishimura, T.1    Vaszar, L.T.2    Faul, J.L.3    Zhao, G.4    Berry, G.J.5    Shi, L.6    Qiu, D.7    Benson, G.8    Pearl, R.G.9    Kao, P.N.10
  • 28
    • 0027502450 scopus 로고
    • Strain differences in the response of Fischer 344 and Sprague-Dawley rats to monocrotaline induced pulmonary vascular disease
    • Pan, L. C., Wilson, D. W. and Segall, H. J. (1993). Strain differences in the response of Fischer 344 and Sprague-Dawley rats to monocrotaline induced pulmonary vascular disease. Toxicology 79, 21-35. (Pubitemid 23116625)
    • (1993) Toxicology , vol.79 , Issue.1 , pp. 21-35
    • Pan, L.C.1    Wilson, D.W.2    Segall, H.J.3
  • 30
    • 0034778907 scopus 로고    scopus 로고
    • Linking a serotonin transporter polymorphism to vascular smooth muscle proliferation in patients with primary pulmonary hypertension
    • DOI 10.1172/JCI200114205
    • Rabinovitch, M. (2001). Linking a serotonin transporter polymorphism to vascular smooth muscle proliferation in patients with primary pulmonary hypertension. J. Clin. Invest. 108, 1109-1111. (Pubitemid 32995368)
    • (2001) Journal of Clinical Investigation , vol.108 , Issue.8 , pp. 1109-1111
    • Rabinovitch, M.1
  • 31
    • 0037623284 scopus 로고    scopus 로고
    • Primary pulmonary hypertension
    • Runo, J. R. and Loyd, J. E. (2003). Primary pulmonary hypertension. Lancet 361, 1533-1544.
    • (2003) Lancet , vol.361 , pp. 1533-1544
    • Runo, J.R.1    Loyd, J.E.2
  • 32
    • 65349171770 scopus 로고    scopus 로고
    • 3-Hydroxy-3-methylglutaryl (HMG)-COA reductase inhibitors and phosphodiesterase type V inhibitors attenuate right ventricular pressure and remodeling in a rat model of pulmonary hypertension
    • Satoh, M. and Satoh, A. (2008). 3-Hydroxy-3-methylglutaryl (HMG)-COA reductase inhibitors and phosphodiesterase type V inhibitors attenuate right ventricular pressure and remodeling in a rat model of pulmonary hypertension. J. Pharm. Pharm. Sci. 11, 118s-130s.
    • (2008) J. Pharm. Pharm. Sci. , vol.11
    • Satoh, M.1    Satoh, A.2
  • 33
    • 61549104663 scopus 로고    scopus 로고
    • Impact of interleukin-6 on hypoxia-induced pulmonary hypertension and lung inflammation in mice
    • Savale, L., Tu, L., Rideau, D., Izziki, M., Maitre, B., Adnot, S. and Eddahibi, S. (2009). Impact of interleukin-6 on hypoxia-induced pulmonary hypertension and lung inflammation in mice. Respir. Res. 10, 6.
    • (2009) Respir. Res. , vol.10 , pp. 6
    • Savale, L.1    Tu, L.2    Rideau, D.3    Izziki, M.4    Maitre, B.5    Adnot, S.6    Eddahibi, S.7
  • 35
    • 23044504042 scopus 로고    scopus 로고
    • Increased susceptibility to pulmonary hypertension in heterozygous BMPR2-mutant mice
    • DOI 10.1161/CIRCULATIONAHA.104.492488
    • Song, Y., Jones, J. E., Beppu, H., Keaney, J. F., Jr, Loscalzo, J. and Zhang, Y.-Y. (2005). Increased susceptibility to pulmonary hypertension in heterozygous BMPR2-mutant mice. Circulation 112, 553-562. (Pubitemid 41060796)
    • (2005) Circulation , vol.112 , Issue.4 , pp. 553-562
    • Song, Y.1    Jones, J.E.2    Beppu, H.3    Keaney Jr., J.F.4    Loscalzo, J.5    Zhang, Y.-Y.6
  • 38
    • 0021256431 scopus 로고
    • Prevention and reversal of hypoxic pulmonary hypertension by calcium antagonists
    • Stanbrook, H. S., Morris, K. G. and McMurtry, I. F. (1984). Prevention and reversal of hypoxic pulmonary hypertension by calcium antagonists. Am. Rev. Resp. Dis. 130, 81-85. (Pubitemid 14092986)
    • (1984) American Review of Respiratory Disease , vol.130 , Issue.1 , pp. 81-85
    • Stanbrook, H.S.1    Morris, K.G.2    McMurtry, I.F.3
  • 40
    • 33646731953 scopus 로고    scopus 로고
    • Role of the adventitia in pulmonary vascular remodeling
    • DOI 10.1152/physiol.00053.2005
    • Stenmark, K. R., Davie, N., Frid, M., Gerasimovskaya, E. and Das, M. (2006). Role of the adventitia in pulmonary vascular remodeling. Physiology (Bethesda) 21, 134-145. (Pubitemid 43752509)
    • (2006) Physiology , vol.21 , Issue.2 , pp. 134-145
    • Stenmark, K.R.1    Davie, N.2    Frid, M.3    Gerasimovskaya, E.4    Das, M.5
  • 41
    • 71949129187 scopus 로고    scopus 로고
    • Animal models of pulmonary arterial hypertension: The hope for etiological discovery and pharmacological cure
    • Stenmark, K. R., Meyrick, B., Galie, N., Mooi, W. J. and McMurtry, I. F. (2009). Animal models of pulmonary arterial hypertension: the hope for etiological discovery and pharmacological cure. Am. J. Physiol. Lung Cell. Mol. Physiol. 297, L1013-L1032.
    • (2009) Am. J. Physiol. Lung Cell. Mol. Physiol. , vol.297
    • Stenmark, K.R.1    Meyrick, B.2    Galie, N.3    Mooi, W.J.4    McMurtry, I.F.5
  • 42
    • 0035130107 scopus 로고    scopus 로고
    • Inhibition of the VEGF receptor 2 combined with chronic hypoxia causes cell death-dependent pulmonary endothelial cell proliferation and severe pulmonary hypertension
    • DOI 10.1096/fj.00-0343com
    • Taraseviciene-Stewart, L., Kasahara, Y., Alger, L., Hirth, P., McMahon, G., Waltenberger, J., Voelkel, N. F. and Tuder, R. M. (2001). Inhibition of the VEGF receptor 2 combined with chronic hypoxia causes cell death-dependent pulmonary endothelial cell proliferation and severe pulmonary hypertension. FASEB J. 15, 427-438. (Pubitemid 32141434)
    • (2001) FASEB Journal , vol.15 , Issue.2 , pp. 427-438
    • Taraseviciene-Stewart, L.1    Kasahara, Y.2    Alger, L.3    Hirth, P.4    Mc Mahon, G.5    Waltenberger, J.6    Voelkel, N.F.7    Tuder, R.M.8
  • 44
    • 59649097082 scopus 로고    scopus 로고
    • Activin-like kinase 5 (ALK5) mediates abnormal proliferation of vascular smooth muscle cells from patients with familial pulmonary arterial hypertension and is involved in the progression of experimental pulmonary arterial hypertension induced by monocrotaline
    • Thomas, M., Docx, C., Holmes, A. M., Beach, S., Duggan, N., England, K., Leblanc, C., Lebret, C., Schindler, F., Raza, F. et al. (2009). Activin-like kinase 5 (ALK5) mediates abnormal proliferation of vascular smooth muscle cells from patients with familial pulmonary arterial hypertension and is involved in the progression of experimental pulmonary arterial hypertension induced by monocrotaline. Am. J. Pathol. 174, 380-389.
    • (2009) Am. J. Pathol. , vol.174 , pp. 380-389
    • Thomas, M.1    Docx, C.2    Holmes, A.M.3    Beach, S.4    Duggan, N.5    England, K.6    Leblanc, C.7    Lebret, C.8    Schindler, F.9    Raza, F.10
  • 45
    • 0028282859 scopus 로고
    • Exuberant endothelial cell growth and elements of inflammation are present in plexiform lesions of pulmonary hypertension
    • Tuder, R. M., Groves, B., Badesch, D. B. and Voelkel, N. F. (1994). Exuberant endothelial cell growth and elements of inflammation are present in plexiform lesions of pulmonary hypertension. Am. J. Pathol. 144, 275-285. (Pubitemid 24165948)
    • (1994) American Journal of Pathology , vol.144 , Issue.2 , pp. 275-285
    • Tuder, R.M.1    Groves, B.2    Badesch, D.B.3    Voelkel, N.F.4
  • 46
    • 33751194658 scopus 로고    scopus 로고
    • Treprostinil in advanced experimental pulmonary hypertension: Beneficial outcome without reversed pulmonary vascular remodeling
    • van Albada, M. E., van Veghel, R., Cromme-Dijkhuis, A. H., Schoemaker, R. G. and Berger, R. M. (2006). Treprostinil in advanced experimental pulmonary hypertension: beneficial outcome without reversed pulmonary vascular remodeling. J. Cardiovasc. Pharmacol. 48, 249-254.
    • (2006) J. Cardiovasc. Pharmacol. , vol.48 , pp. 249-254
    • Van Albada, M.E.1    Van Veghel, R.2    Cromme-Dijkhuis, A.H.3    Schoemaker, R.G.4    Berger, R.M.5
  • 50
    • 42949178711 scopus 로고    scopus 로고
    • Bone morphogenetic protein (BMP) type II receptor is required for BMP-mediated growth arrest and differentiation in pulmonary artery smooth muscle cells
    • Yu, P. B., Deng, D. Y., Beppu, H., Hong, C. C., Lai, C., Hoyng, S. A., Kawai, N. and Bloch, K. D. (2008). Bone morphogenetic protein (BMP) type II receptor is required for BMP-mediated growth arrest and differentiation in pulmonary artery smooth muscle cells. J. Biol. Chem. 283, 3877-3888.
    • (2008) J. Biol. Chem. , vol.283 , pp. 3877-3888
    • Yu, P.B.1    Deng, D.Y.2    Beppu, H.3    Hong, C.C.4    Lai, C.5    Hoyng, S.A.6    Kawai, N.7    Bloch, K.D.8
  • 51
  • 52
    • 0032491187 scopus 로고    scopus 로고
    • + channels in pulmonary artery smooth muscle cells of patients with primary pulmonary hypertension
    • Yuan, J. X., Aldinger, A. M., Juhaszova, M., Wang, J., Conte, J. V., Jr, Gaine, S. P., Orens, J. B. and Rubin, L. J. (1998). Dysfunctional voltage-gated K+ channels in pulmonary artery smooth muscle cells of patients with primary pulmonary hypertension. Circulation 98, 1400-1406. (Pubitemid 28462800)
    • (1998) Circulation , vol.98 , Issue.14 , pp. 1400-1406
    • Yuan, J.X.-J.1    Aldinger, A.M.2    Juhaszova, M.3    Wang, J.4    Conte Jr., J.V.5    Gaine, S.P.6    Orens, J.B.7    Rubin, L.J.8
  • 55
    • 65349130026 scopus 로고    scopus 로고
    • Impact of calcium-channel blockers on right heart function in a controlled model of chronic pulmonary hypertension
    • Zierer, A., Voeller, R. K., Melby, S. J., Steendijk, P. and Moon, M. R. (2009). Impact of calcium-channel blockers on right heart function in a controlled model of chronic pulmonary hypertension. Eur. J. Anaesthesiol. 26, 253-259.
    • (2009) Eur. J. Anaesthesiol. , vol.26 , pp. 253-259
    • Zierer, A.1    Voeller, R.K.2    Melby, S.J.3    Steendijk, P.4    Moon, M.R.5


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