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Volumn 14, Issue 1-2, 2010, Pages 154-164

Loss of cks1 homeostasis deregulates cell division cycle

Author keywords

Cancer; Cell cycle; Cks1; P27; Ubiquitin ligase

Indexed keywords

CARRIER PROTEIN; CDK2 PROTEIN, HUMAN; CKS1B PROTEIN, HUMAN; CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE INHIBITOR 1B; S PHASE KINASE ASSOCIATED PROTEIN;

EID: 77951959506     PISSN: 15821838     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1582-4934.2009.00698.x     Document Type: Article
Times cited : (31)

References (79)
  • 1
    • 0022573987 scopus 로고
    • The fission yeast cell cycle control gene cdc2+; isolation of a sequence sucl+ that suppresses cdc2 mutant function
    • Hayles J, Beach DH, Durkacz B. The fission yeast cell cycle control gene cdc2+; isolation of a sequence sucl+ that suppresses cdc2 mutant function. Mol Gen Genet. 1986, 202:291-3.
    • (1986) Mol Gen Genet. , vol.202 , pp. 291-293
    • Hayles, J.1    Beach, D.H.2    Durkacz, B.3
  • 2
    • 0000275636 scopus 로고
    • Sucl+ is an essential gene involved in both the cell cycle and growth in fission yeast
    • Hayles J, Aves S, Nurse P. sucl+ is an essential gene involved in both the cell cycle and growth in fission yeast. EMBO J. 1986, 5:3373-9.
    • (1986) EMBO J. , vol.5 , pp. 3373-3379
    • Hayles, J.1    Aves, S.2    Nurse, P.3
  • 3
    • 0023161016 scopus 로고
    • Sucl+ encodes a predicted 13-kilodalton protein that is essential for cell viability and directly involved in the division cycle of Schizosaccharomyces pombe
    • Hindley J, Phear G, Stein M. Sucl+ encodes a predicted 13-kilodalton protein that is essential for cell viability and directly involved in the division cycle of Schizosaccharomyces pombe. Mol Cell Biol. 1987, 7:504-11.
    • (1987) Mol Cell Biol. , vol.7 , pp. 504-511
    • Hindley, J.1    Phear, G.2    Stein, M.3
  • 4
    • 0023658309 scopus 로고
    • Identification of p34 and p13, human homologs of the cell cycle regulators of fission yeast encoded by cdc2+ and suc1+
    • Draetta G, Brizuela L, Potashkin J. Identification of p34 and p13, human homologs of the cell cycle regulators of fission yeast encoded by cdc2+ and suc1+. Cell. 1987, 50:319-25.
    • (1987) Cell. , vol.50 , pp. 319-325
    • Draetta, G.1    Brizuela, L.2    Potashkin, J.3
  • 5
    • 0024997502 scopus 로고
    • Human cDNAs encoding homologs of the small p34cdc28/cdc2-associated protein of Saccharomyces cerevisiae and Schizosac charomyces pombe
    • Richardson HE, Stueland CS, Thomas J. Human cDNAs encoding homologs of the small p34cdc28/cdc2-associated protein of Saccharomyces cerevisiae and Schizosac charomyces pombe. Genes Dev. 1990, 4:1332-44.
    • (1990) Genes Dev. , vol.4 , pp. 1332-1344
    • Richardson, H.E.1    Stueland, C.S.2    Thomas, J.3
  • 6
    • 0024553955 scopus 로고
    • The Saccharomyces cerevisiae CKS1 gene, a homolog of the Schizosaccharomyces pombe sucl+ gene, encodes a subunit of the cdc28 protein kinase complex
    • Hadwiger JA, Wittenberg C, Mendenhall MD. The Saccharomyces cerevisiae CKS1 gene, a homolog of the Schizosaccharomyces pombe sucl+ gene, encodes a subunit of the cdc28 protein kinase complex. Mol Cell Biol. 1989, 9:2034-41.
    • (1989) Mol Cell Biol. , vol.9 , pp. 2034-2041
    • Hadwiger, J.A.1    Wittenberg, C.2    Mendenhall, M.D.3
  • 7
    • 0029784224 scopus 로고    scopus 로고
    • Xe-p9, a Xenopus Suc1/Cks homolog, has multiple essential roles in cell cycle control
    • Patra D, Dunphy WG. Xe-p9, a Xenopus Suc1/Cks homolog, has multiple essential roles in cell cycle control. Genes Dev. 1996, 10:1503-15.
    • (1996) Genes Dev. , vol.10 , pp. 1503-1515
    • Patra, D.1    Dunphy, W.G.2
  • 8
    • 0023446949 scopus 로고
    • Pl3sucl acts in the fission yeast cell division cycle as a component of the p34cdc2 protein kinase
    • Brizuela L, Draetta G, Beach D. pl3sucl acts in the fission yeast cell division cycle as a component of the p34cdc2 protein kinase. EMBO J. 1987, 6:3507-14.
    • (1987) EMBO J. , vol.6 , pp. 3507-3514
    • Brizuela, L.1    Draetta, G.2    Beach, D.3
  • 9
    • 0024475228 scopus 로고
    • Regulation of p34cdc2 protein kinase during mitosis
    • Moreno S, Hayles J, Nurse P. Regulation of p34cdc2 protein kinase during mitosis. Cell. 1989, 58:361-72.
    • (1989) Cell. , vol.58 , pp. 361-372
    • Moreno, S.1    Hayles, J.2    Nurse, P.3
  • 10
    • 0028986043 scopus 로고
    • P13suc1 of Schizosaccharomyces pombe regulates two distinct forms of the mitotic cdc2 kinase
    • Basi G, Draetta G. p13suc1 of Schizosaccharomyces pombe regulates two distinct forms of the mitotic cdc2 kinase. Mol Cell Biol. 1995, 15:2028-36.
    • (1995) Mol Cell Biol. , vol.15 , pp. 2028-2036
    • Basi, G.1    Draetta, G.2
  • 11
    • 0027153159 scopus 로고
    • The Cdk-associated protein Cks1 functions both in G1 and G2 in Saccharomyces cerevisiae
    • Tang Y, Reed SI. The Cdk-associated protein Cks1 functions both in G1 and G2 in Saccharomyces cerevisiae. Genes Dev. 1993, 7:822-32.
    • (1993) Genes Dev. , vol.7 , pp. 822-832
    • Tang, Y.1    Reed, S.I.2
  • 12
    • 0033564697 scopus 로고    scopus 로고
    • CDK inhibitors: positive and negative regulators of G1-phase progression
    • Sherr CJ, Roberts JM. CDK inhibitors: positive and negative regulators of G1-phase progression. Genes Dev. 1999, 13:1501-12.
    • (1999) Genes Dev. , vol.13 , pp. 1501-1512
    • Sherr, C.J.1    Roberts, J.M.2
  • 13
    • 0034162636 scopus 로고    scopus 로고
    • Preclinical and clinical development of cyclin dependent kinase modulators
    • Senderowics AM, Sausville EA. Preclinical and clinical development of cyclin dependent kinase modulators. J Natl Cancer Inst. 2000, 92:376-87.
    • (2000) J Natl Cancer Inst. , vol.92 , pp. 376-387
    • Senderowics, A.M.1    Sausville, E.A.2
  • 14
    • 0024294002 scopus 로고
    • Cdc2 is a component of the M-phase-specific histone H1 kinase: evidence for identity with MPF
    • Arion D, Meijer L, Brizuela L. cdc2 is a component of the M-phase-specific histone H1 kinase: evidence for identity with MPF. Cell. 1988, 55:371-8.
    • (1988) Cell. , vol.55 , pp. 371-378
    • Arion, D.1    Meijer, L.2    Brizuela, L.3
  • 15
    • 0031737085 scopus 로고    scopus 로고
    • Regulation of Cdc28 cyclin-dependent protein kinase activity during the cell cycle of the yeast Saccharomyces cerevisiae
    • Mendenhall MD, Hodge AE. Regulation of Cdc28 cyclin-dependent protein kinase activity during the cell cycle of the yeast Saccharomyces cerevisiae. Microbio Mol Bio Re. 1998, 62:1191-243.
    • (1998) Microbio Mol Bio Re. , vol.62 , pp. 1191-1243
    • Mendenhall, M.D.1    Hodge, A.E.2
  • 16
    • 0028675322 scopus 로고
    • Cyclin-dependent kinases: regulators of the cell cycle and more
    • Murray AW. Cyclin-dependent kinases: regulators of the cell cycle and more. Chem Biol. 1994, 4:191-5.
    • (1994) Chem Biol. , vol.4 , pp. 191-195
    • Murray, A.W.1
  • 18
    • 0036284778 scopus 로고    scopus 로고
    • The anaphase-promoting complex: proteolysis in mitosis and beyond
    • Peters JM. The anaphase-promoting complex: proteolysis in mitosis and beyond. Mol Cell. 2002, 9:931-43.
    • (2002) Mol Cell. , vol.9 , pp. 931-943
    • Peters, J.M.1
  • 19
    • 0033601171 scopus 로고    scopus 로고
    • The xenopus suc1/cks protein promotes the phosphorylation of G2/M regulators
    • Patra D, Wang SX, Kumagai A. The xenopus suc1/cks protein promotes the phosphorylation of G2/M regulators. J Biol Chem. 1999, 274:36839-42.
    • (1999) J Biol Chem. , vol.274 , pp. 36839-36842
    • Patra, D.1    Wang, S.X.2    Kumagai, A.3
  • 20
    • 0023753715 scopus 로고
    • The Xenopus cdc2 protein is a component of MPF, a cytoplasmic regulator of mitosis
    • Dunphy WG, Brizuela L, Beach D. The Xenopus cdc2 protein is a component of MPF, a cytoplasmic regulator of mitosis. Cell. 1988, 54:423-31.
    • (1988) Cell. , vol.54 , pp. 423-431
    • Dunphy, W.G.1    Brizuela, L.2    Beach, D.3
  • 21
    • 0033134778 scopus 로고    scopus 로고
    • Cyclin-dependent kinase and Cks/Suc1 interact with the proteasome in yeast to control proteolysis of M-phase targets
    • Kaiser P, Moncollin V, Clarke DJ. Cyclin-dependent kinase and Cks/Suc1 interact with the proteasome in yeast to control proteolysis of M-phase targets. Genes Dev. 1999, 13:1190-202.
    • (1999) Genes Dev. , vol.13 , pp. 1190-1202
    • Kaiser, P.1    Moncollin, V.2    Clarke, D.J.3
  • 22
    • 0032529162 scopus 로고    scopus 로고
    • Xe-p9, a Xenopus Suc1/Cks protein, is essential for the Cdc2-dependent phosphorylation of the anaphase promoting complex at mitosis
    • Patra D, Dunphy WG. Xe-p9, a Xenopus Suc1/Cks protein, is essential for the Cdc2-dependent phosphorylation of the anaphase promoting complex at mitosis. Genes Dev. 1998, 12:2549-59.
    • (1998) Genes Dev. , vol.12 , pp. 2549-2559
    • Patra, D.1    Dunphy, W.G.2
  • 23
    • 0030741534 scopus 로고    scopus 로고
    • Binding of activated cyclosome to p13(suc1). Use for affinity purification
    • Sudakin V, Shteinberg M, Ganoth D. Binding of activated cyclosome to p13(suc1). Use for affinity purification. J Biol Chem. 1997, 272:18051-9.
    • (1997) J Biol Chem. , vol.272 , pp. 18051-18059
    • Sudakin, V.1    Shteinberg, M.2    Ganoth, D.3
  • 24
    • 51349096486 scopus 로고    scopus 로고
    • Cyclin-dependent kinase-associated proteins Cks1 and Cks2 are essential during early embryogenesis and for cell cycle progression in somatic cells
    • Martinsson-Ahlzen HS, Liberal V, Grunenfelder B. Cyclin-dependent kinase-associated proteins Cks1 and Cks2 are essential during early embryogenesis and for cell cycle progression in somatic cells. Mol Cell Biol. 2008, 28:5698-709.
    • (2008) Mol Cell Biol. , vol.28 , pp. 5698-5709
    • Martinsson-Ahlzen, H.S.1    Liberal, V.2    Grunenfelder, B.3
  • 25
    • 0042304165 scopus 로고    scopus 로고
    • Cks1-dependent proteasome recruitment and activation of CDC20 transcription in budding yeast
    • Morris MC, Kaiser P, Rudyak S. Cks1-dependent proteasome recruitment and activation of CDC20 transcription in budding yeast. Nature. 2003, 423:1009-13.
    • (2003) Nature. , vol.423 , pp. 1009-1013
    • Morris, M.C.1    Kaiser, P.2    Rudyak, S.3
  • 26
    • 11344274449 scopus 로고    scopus 로고
    • A kinase-independent function of cks1 and cdk1 in regulation of transcription
    • Yu VPCC, Baskerville C, Grunenfelder B. A kinase-independent function of cks1 and cdk1 in regulation of transcription. Mol Cell. 2005, 17:145-51.
    • (2005) Mol Cell. , vol.17 , pp. 145-151
    • Yu, V.P.C.C.1    Baskerville, C.2    Grunenfelder, B.3
  • 27
    • 37049006067 scopus 로고    scopus 로고
    • Cks1 regulates cdk1 expression: a novel role during mitotic entry in breast cancer cells
    • Westbrook L, Manuvakhova M, Kern FG. Cks1 regulates cdk1 expression: a novel role during mitotic entry in breast cancer cells. Cancer Res. 2007, 67:11393-401.
    • (2007) Cancer Res. , vol.67 , pp. 11393-11401
    • Westbrook, L.1    Manuvakhova, M.2    Kern, F.G.3
  • 28
    • 0031741136 scopus 로고    scopus 로고
    • Ectopic expression of cdc2/cdc28 kinase subunit Homo sapiens 1 uncouples cyclin B metabolism from the mitotic spindle cell cycle checkpoint
    • Hixon ML, Flores AI, Wagner MW. Ectopic expression of cdc2/cdc28 kinase subunit Homo sapiens 1 uncouples cyclin B metabolism from the mitotic spindle cell cycle checkpoint. Mol Cell Biol. 1998, 18:6224-37.
    • (1998) Mol Cell Biol. , vol.18 , pp. 6224-6237
    • Hixon, M.L.1    Flores, A.I.2    Wagner, M.W.3
  • 29
    • 34147096007 scopus 로고    scopus 로고
    • Expression of cyclin-dependent kinase subunit 1 (Cks1) is regulated during the cell cycle by a CDE/CHR tandem element and is down regulated by p53 but not by p63 or p73
    • Rother K, Li YY, Tschop K. Expression of cyclin-dependent kinase subunit 1 (Cks1) is regulated during the cell cycle by a CDE/CHR tandem element and is down regulated by p53 but not by p63 or p73. Cell Cycle. 2007, 6:853-62.
    • (2007) Cell Cycle. , vol.6 , pp. 853-862
    • Rother, K.1    Li, Y.Y.2    Tschop, K.3
  • 30
    • 1642378661 scopus 로고    scopus 로고
    • Control of the SCF(Skp2-Cks1) ubiquitin ligase by the APC/C(Cdh1) ubiquitin ligase
    • Bashir T, Dorrello NV, Amador V. Control of the SCF(Skp2-Cks1) ubiquitin ligase by the APC/C(Cdh1) ubiquitin ligase. Nature. 2004, 428:190-3.
    • (2004) Nature. , vol.428 , pp. 190-193
    • Bashir, T.1    Dorrello, N.V.2    Amador, V.3
  • 31
    • 0242539861 scopus 로고    scopus 로고
    • Cks1 is degraded via the ubiquitin-proteasome pathway in a cell cycle-dependent manner
    • Hattori T, Kitagawa K, Uchida C. Cks1 is degraded via the ubiquitin-proteasome pathway in a cell cycle-dependent manner. Genes Cells. 2003, 8:889-96.
    • (2003) Genes Cells. , vol.8 , pp. 889-896
    • Hattori, T.1    Kitagawa, K.2    Uchida, C.3
  • 32
    • 28544449224 scopus 로고    scopus 로고
    • Forkhead Box M1 regulates the transcriptional network of genes essential for mitotic progression and genes encoding the SCF (Skp2-Cks1) ubiquitin ligase
    • Wang IC, Chen YJ, Hughes D. Forkhead Box M1 regulates the transcriptional network of genes essential for mitotic progression and genes encoding the SCF (Skp2-Cks1) ubiquitin ligase. Mol Cell Biol. 2005, 25:10875-94.
    • (2005) Mol Cell Biol. , vol.25 , pp. 10875-10894
    • Wang, I.C.1    Chen, Y.J.2    Hughes, D.3
  • 33
    • 34249097128 scopus 로고    scopus 로고
    • Myc targets cks1 to provoke the suppression of p27Kip1, proliferation and lymphomagenesis
    • Keller UB, Old JB, Dorsey FC. Myc targets cks1 to provoke the suppression of p27Kip1, proliferation and lymphomagenesis. EMBO J. 2007, 26:2562-74.
    • (2007) EMBO J. , vol.26 , pp. 2562-2574
    • Keller, U.B.1    Old, J.B.2    Dorsey, F.C.3
  • 34
    • 33749679789 scopus 로고    scopus 로고
    • CD28 costimulation mediates transcription of skp2 and cks1, the substrate recognition components of SCFSkp2 ubiquitin ligase that leads p27kip1 to degradation
    • Appleman LJ, Chernova I, Li L. CD28 costimulation mediates transcription of skp2 and cks1, the substrate recognition components of SCFSkp2 ubiquitin ligase that leads p27kip1 to degradation. Cell Cycle. 2006, 5:2123-9.
    • (2006) Cell Cycle. , vol.5 , pp. 2123-2129
    • Appleman, L.J.1    Chernova, I.2    Li, L.3
  • 35
    • 1442284076 scopus 로고    scopus 로고
    • Negative regulation of SCFSkp2 ubiquitin ligase by TGF beta signaling
    • Wang W, Ungermannova D, Jin J. Negative regulation of SCFSkp2 ubiquitin ligase by TGF beta signaling. Oncogene. 2004, 23:1064-75.
    • (2004) Oncogene. , vol.23 , pp. 1064-1075
    • Wang, W.1    Ungermannova, D.2    Jin, J.3
  • 36
    • 0028799105 scopus 로고
    • Transforming growth factor β down-regulation of ckshs1 transcripts in growth-inhibited epithelial cells
    • Simon KE, Cha HH, Firestone GL. Transforming growth factor β down-regulation of ckshs1 transcripts in growth-inhibited epithelial cells. Cell Growth Differ. 1995, 6:1261-69.
    • (1995) Cell Growth Differ. , vol.6 , pp. 1261-1269
    • Simon, K.E.1    Cha, H.H.2    Firestone, G.L.3
  • 37
    • 33847027884 scopus 로고    scopus 로고
    • Mutant B-RAF signaling and cyclin D1 regulate Cks1/S-phase kinase-associated protein 2-mediated degradation of p27Kip1 in human melanoma cells
    • Bhatt KV, Hu R, Spofford LS. Mutant B-RAF signaling and cyclin D1 regulate Cks1/S-phase kinase-associated protein 2-mediated degradation of p27Kip1 in human melanoma cells. Oncogene. 2007, 26:1056-66.
    • (2007) Oncogene. , vol.26 , pp. 1056-1066
    • Bhatt, K.V.1    Hu, R.2    Spofford, L.S.3
  • 38
    • 0029034120 scopus 로고
    • Crystal structure of the human cell cycle protein CksHs1: single domain fold with similarity to kinase N-lobe domain
    • Arvai AS, Bourne Y, Hickey MJ. Crystal structure of the human cell cycle protein CksHs1: single domain fold with similarity to kinase N-lobe domain. J Mol Biol. 1995, 249:835-42.
    • (1995) J Mol Biol. , vol.249 , pp. 835-842
    • Arvai, A.S.1    Bourne, Y.2    Hickey, M.J.3
  • 39
    • 0029918062 scopus 로고    scopus 로고
    • Crystal structure and mutational analysis of the human cdk2 kinase complex with cell cycle-regulatory protein ckshs1
    • Bourne Y, Watson MH, Hickey MJ. Crystal structure and mutational analysis of the human cdk2 kinase complex with cell cycle-regulatory protein ckshs1. Cell. 1996, 84:863-74.
    • (1996) Cell. , vol.84 , pp. 863-874
    • Bourne, Y.1    Watson, M.H.2    Hickey, M.J.3
  • 40
    • 24044443897 scopus 로고    scopus 로고
    • Role of conformational heterogeneity in domain swapping and adapter function of the cks proteins
    • Seeliger MA, Spichty M, Kelly SE. Role of conformational heterogeneity in domain swapping and adapter function of the cks proteins. J Biol Chem. 2005, 280:30448-59.
    • (2005) J Biol Chem. , vol.280 , pp. 30448-30459
    • Seeliger, M.A.1    Spichty, M.2    Kelly, S.E.3
  • 41
    • 0035092687 scopus 로고    scopus 로고
    • The cell-cycle regulatory protein Cks1 is required for SCF(Skp2)-mediated ubiquitinylation of p27
    • Ganoth D, Bornstein G, Ko TK. The cell-cycle regulatory protein Cks1 is required for SCF(Skp2)-mediated ubiquitinylation of p27. Nat Cell Biol. 2001, 3:321-4.
    • (2001) Nat Cell Biol. , vol.3 , pp. 321-324
    • Ganoth, D.1    Bornstein, G.2    Ko, T.K.3
  • 42
    • 0035265829 scopus 로고    scopus 로고
    • A cdk-independent function of mammalian cks1: targeting of SCFskp2 to the cdk inhibitor p27Kip1
    • Spruck C, Strohmaier H, Watson M. A cdk-independent function of mammalian cks1: targeting of SCFskp2 to the cdk inhibitor p27Kip1. Mol Cell. 2001, 7:639-50.
    • (2001) Mol Cell. , vol.7 , pp. 639-650
    • Spruck, C.1    Strohmaier, H.2    Watson, M.3
  • 43
    • 0033578073 scopus 로고    scopus 로고
    • P27(kip1) ubiquitination and degradation is regulated by the SCF(skp2) complex through phosphorylated Thr187 in p27
    • Tsvetkov LM, Yeh KH, Lee SJ. p27(kip1) ubiquitination and degradation is regulated by the SCF(skp2) complex through phosphorylated Thr187 in p27. Curr Biol. 1999, 9:661-4.
    • (1999) Curr Biol. , vol.9 , pp. 661-664
    • Tsvetkov, L.M.1    Yeh, K.H.2    Lee, S.J.3
  • 44
    • 0033176887 scopus 로고    scopus 로고
    • Skp2 is required for ubiquitin-mediated degradation of the cdk inhibitor p27
    • Carrano AC, Eytan E, Hershko A. Skp2 is required for ubiquitin-mediated degradation of the cdk inhibitor p27. Nat Cell Biol. 1999, 4:193-9.
    • (1999) Nat Cell Biol. , vol.4 , pp. 193-199
    • Carrano, A.C.1    Eytan, E.2    Hershko, A.3
  • 45
    • 0028980273 scopus 로고
    • P19 skpl and p45 skp2 are essential elements of the cyclin A-cdk2 S phase kinase
    • Zhang H, Kobayashi R, Galaktionov K. p19 skpl and p45 skp2 are essential elements of the cyclin A-cdk2 S phase kinase. Cell. 1995, 82:915-25.
    • (1995) Cell. , vol.82 , pp. 915-925
    • Zhang, H.1    Kobayashi, R.2    Galaktionov, K.3
  • 46
    • 0035816657 scopus 로고    scopus 로고
    • Association of the cell cycle regulatory proteins p45skp2 and ckshs1. Functional effect on cdk2 complex formation and kinase activity
    • Mongay L, Plaza S, Vigorito E. Association of the cell cycle regulatory proteins p45skp2 and ckshs1. Functional effect on cdk2 complex formation and kinase activity. J Biol Chem. 2001, 276:25030-6.
    • (2001) J Biol Chem. , vol.276 , pp. 25030-25036
    • Mongay, L.1    Plaza, S.2    Vigorito, E.3
  • 47
    • 0042858122 scopus 로고    scopus 로고
    • A negatively charged amino acid in skp2 is required for skp2-cks1 interaction and ubiquitination of p27kip1
    • Wang W, Ungermannova D, Chen L. A negatively charged amino acid in skp2 is required for skp2-cks1 interaction and ubiquitination of p27kip1. J Biol Chem. 2003, 278:32390-6.
    • (2003) J Biol Chem. , vol.278 , pp. 32390-32396
    • Wang, W.1    Ungermannova, D.2    Chen, L.3
  • 48
    • 0038583881 scopus 로고    scopus 로고
    • Protein-protein interactions involved in the recognition of p27 by E3 ubiquitin ligase
    • Xu K, Belunis C, Chu W. Protein-protein interactions involved in the recognition of p27 by E3 ubiquitin ligase. Biochem J. 2003, 371:957-64.
    • (2003) Biochem J. , vol.371 , pp. 957-964
    • Xu, K.1    Belunis, C.2    Chu, W.3
  • 49
    • 0035810976 scopus 로고    scopus 로고
    • Protein destruction: adapting roles for cks1 proteins
    • Harper JW. Protein destruction: adapting roles for cks1 proteins. Curr Biol. 2001, 11:431-5.
    • (2001) Curr Biol. , vol.11 , pp. 431-435
    • Harper, J.W.1
  • 50
    • 0033135878 scopus 로고    scopus 로고
    • Ubiquitination of p27 is regulated by cdk-dependent phosphorylation and trimeric complex formation
    • Montagnoli A, Fiore F, Eytan E. Ubiquitination of p27 is regulated by cdk-dependent phosphorylation and trimeric complex formation. Genes Dev. 1999, 13:1181-9.
    • (1999) Genes Dev. , vol.13 , pp. 1181-1189
    • Montagnoli, A.1    Fiore, F.2    Eytan, E.3
  • 51
    • 0036829681 scopus 로고    scopus 로고
    • Three different binding sites of cks1 are required for p27-ubiquitin ligation
    • Sitry D, Seeliger MA, Ko TK. Three different binding sites of cks1 are required for p27-ubiquitin ligation. J Biol Chem. 2002, 277:42233-40.
    • (2002) J Biol Chem. , vol.277 , pp. 42233-42240
    • Sitry, D.1    Seeliger, M.A.2    Ko, T.K.3
  • 52
    • 24044471278 scopus 로고    scopus 로고
    • Ubiquitination of p27kip1 requires physical interaction with cyclin E and probable phosphate recognition by skp2
    • Ungermannova D, Gao Y, Liu X. Ubiquitination of p27kip1 requires physical interaction with cyclin E and probable phosphate recognition by skp2. J Biol Chem. 2005, 280:30301-9.
    • (2005) J Biol Chem. , vol.280 , pp. 30301-30309
    • Ungermannova, D.1    Gao, Y.2    Liu, X.3
  • 53
    • 34447558572 scopus 로고    scopus 로고
    • Substrate recognition and ubiquitination of SCFskp2/cks1 ubiquitin-protein isopeptide ligase
    • Xu S, Abbasian M, Patel P. Substrate recognition and ubiquitination of SCFskp2/cks1 ubiquitin-protein isopeptide ligase. J Biol Chem. 2007, 282:15462-70.
    • (2007) J Biol Chem. , vol.282 , pp. 15462-15470
    • Xu, S.1    Abbasian, M.2    Patel, P.3
  • 54
    • 25844441096 scopus 로고    scopus 로고
    • Structural basis of the cks1-dependent recognition of p27Kip1 by the SCFSkp2 ubiquitin ligase
    • Hao B, Zheng N, Schulman BA. Structural basis of the cks1-dependent recognition of p27Kip1 by the SCFSkp2 ubiquitin ligase. Mol Cell. 2005, 20:9-19.
    • (2005) Mol Cell. , vol.20 , pp. 9-19
    • Hao, B.1    Zheng, N.2    Schulman, B.A.3
  • 55
    • 2942716826 scopus 로고    scopus 로고
    • Noncatalytic requirement for cyclin A-cdk2 in p27 turnover
    • Zhu XH, Nguyen H, Halicka HD. Noncatalytic requirement for cyclin A-cdk2 in p27 turnover. Mol Cell Biol. 2004, 24:6058-66.
    • (2004) Mol Cell Biol. , vol.24 , pp. 6058-6066
    • Zhu, X.H.1    Nguyen, H.2    Halicka, H.D.3
  • 56
    • 0038152755 scopus 로고    scopus 로고
    • Role of the SCFSkp2 ubiquitin ligase in the degradation of p21cip1 in S phase
    • Bornstein G, Bloom J, Sitry-Shevah D. Role of the SCFSkp2 ubiquitin ligase in the degradation of p21cip1 in S phase. J Biol Chem. 2003, 278:25752-7.
    • (2003) J Biol Chem. , vol.278 , pp. 25752-25757
    • Bornstein, G.1    Bloom, J.2    Sitry-Shevah, D.3
  • 57
    • 0037112174 scopus 로고    scopus 로고
    • The pRb-related protein p130 is regulated by phosphorylation-dependent proteolysis via the protein-ubiquitin ligase SCFskp2
    • Tedesco D, Lukas J, Reed SI. The pRb-related protein p130 is regulated by phosphorylation-dependent proteolysis via the protein-ubiquitin ligase SCFskp2. Genes Dev. 2002, 16:2946-57.
    • (2002) Genes Dev. , vol.16 , pp. 2946-2957
    • Tedesco, D.1    Lukas, J.2    Reed, S.I.3
  • 58
    • 0034595292 scopus 로고    scopus 로고
    • Targeted disruption of skp2 results in accumulation of cyclin E and p27(kip1), polyploidy and centrosome overduplication
    • Nakayama K, Nagahama H, Minamishima YA. Targeted disruption of skp2 results in accumulation of cyclin E and p27(kip1), polyploidy and centrosome overduplication. EMBO J. 2000, 19:2069-81.
    • (2000) EMBO J. , vol.19 , pp. 2069-2081
    • Nakayama, K.1    Nagahama, H.2    Minamishima, Y.A.3
  • 59
    • 0041836324 scopus 로고    scopus 로고
    • Degradation of p57kip2 mediated by SCFskp2-dependent ubiquitylation
    • Kamura T, Hara T, Kotoshiba S. Degradation of p57kip2 mediated by SCFskp2-dependent ubiquitylation. PNAS. 2003, 100:10231-6.
    • (2003) PNAS. , vol.100 , pp. 10231-10236
    • Kamura, T.1    Hara, T.2    Kotoshiba, S.3
  • 60
    • 0034660079 scopus 로고    scopus 로고
    • Degradation of B-Myb by ubiquitin-mediated proteolysis: involvement of the cdc34-SCFp45skp2 pathway
    • Charrasse S, Carena I, Brondani V. Degradation of B-Myb by ubiquitin-mediated proteolysis: involvement of the cdc34-SCFp45skp2 pathway. Oncogene. 2000, 19:2986-95.
    • (2000) Oncogene. , vol.19 , pp. 2986-2995
    • Charrasse, S.1    Carena, I.2    Brondani, V.3
  • 61
    • 0036208817 scopus 로고    scopus 로고
    • Human Origin Recognition Complex large subunit is degraded by ubiquitin-mediated proteolysis after initiation of DNA replication
    • Mendez J, Zou-Yang XH, Kim SY. Human Origin Recognition Complex large subunit is degraded by ubiquitin-mediated proteolysis after initiation of DNA replication. Mol Cell. 2002, 9:481-91.
    • (2002) Mol Cell. , vol.9 , pp. 481-491
    • Mendez, J.1    Zou-Yang, X.H.2    Kim, S.Y.3
  • 62
    • 42949105096 scopus 로고    scopus 로고
    • Cdc20 and cks direct the spindle checkpoint-independent destruction of cyclin A
    • Wolthuis R, Farrace LC, Zon WV. cdc20 and cks direct the spindle checkpoint-independent destruction of cyclin A. Mol Cell. 2008, 30:290-302.
    • (2008) Mol Cell. , vol.30 , pp. 290-302
    • Wolthuis, R.1    Farrace, L.C.2    Zon, W.V.3
  • 63
    • 0030292994 scopus 로고    scopus 로고
    • Cell cycle: reaching for a role for the Cks proteins
    • Pines J. Cell cycle: reaching for a role for the Cks proteins. Curr Biol. 1996, 6:1399-402.
    • (1996) Curr Biol. , vol.6 , pp. 1399-1402
    • Pines, J.1
  • 64
    • 25144448570 scopus 로고    scopus 로고
    • RNA silencing of cks1 induced G2/M arrest and apoptosis in human lung cancer cells
    • Tsai YS, Chang HC, Chuang LY. RNA silencing of cks1 induced G2/M arrest and apoptosis in human lung cancer cells. IUBMB Life. 2005, 57:583-9.
    • (2005) IUBMB Life. , vol.57 , pp. 583-589
    • Tsai, Y.S.1    Chang, H.C.2    Chuang, L.Y.3
  • 65
    • 46049116296 scopus 로고    scopus 로고
    • Aberrant expression of cks1 and cks2 contributes to prostate tumorigenesis by promoting proliferation and inhibiting programmed cell death
    • Lan Y, Zhang Y, Wang J. Aberrant expression of cks1 and cks2 contributes to prostate tumorigenesis by promoting proliferation and inhibiting programmed cell death. Int J Cancer. 2008, 123:543-51.
    • (2008) Int J Cancer. , vol.123 , pp. 543-551
    • Lan, Y.1    Zhang, Y.2    Wang, J.3
  • 66
    • 33644875101 scopus 로고    scopus 로고
    • The expression of the ubiquitin ligase subunit cks1 in human breast cancer
    • Slotky M, Shapira M, Ben-Izhak O. The expression of the ubiquitin ligase subunit cks1 in human breast cancer. Breast Cancer Res. 2005, 7:737-44.
    • (2005) Breast Cancer Res. , vol.7 , pp. 737-744
    • Slotky, M.1    Shapira, M.2    Ben-Izhak, O.3
  • 67
    • 9644253021 scopus 로고    scopus 로고
    • Role of cks1 overexpression in oral squamous cell carcinomas. Cooperation with skp2 in promoting p27 degradation
    • Kitajima S, Kudo Y, Ogawa I. Role of cks1 overexpression in oral squamous cell carcinomas. Cooperation with skp2 in promoting p27 degradation. Am J Pathol. 2004, 165:2147-55.
    • (2004) Am J Pathol. , vol.165 , pp. 2147-2155
    • Kitajima, S.1    Kudo, Y.2    Ogawa, I.3
  • 68
    • 34250197222 scopus 로고    scopus 로고
    • Increased skp2 and cks1 gene expression contributes to the progression of human urothelial carcinoma
    • Kawakami K, Enokida H, Tachiwada T. Increased skp2 and cks1 gene expression contributes to the progression of human urothelial carcinoma. J Urol. 2007, 178:301-7.
    • (2007) J Urol. , vol.178 , pp. 301-307
    • Kawakami, K.1    Enokida, H.2    Tachiwada, T.3
  • 69
    • 15744382959 scopus 로고    scopus 로고
    • The prognostic impact of the ubiquitin ligase subunits skp2 and cks1 in colorectal carcinoma
    • Shapira M, Ben-Izhak O, Linn S. The prognostic impact of the ubiquitin ligase subunits skp2 and cks1 in colorectal carcinoma. Cancer. 2005, 103:1336-46.
    • (2005) Cancer. , vol.103 , pp. 1336-1346
    • Shapira, M.1    Ben-Izhak, O.2    Linn, S.3
  • 70
    • 0344198099 scopus 로고    scopus 로고
    • Cyclin-dependent kinase 1 gene expression is associated with poor prognosis in gastric carcinoma
    • Masuda TA, Inoue H, Nishida K. Cyclin-dependent kinase 1 gene expression is associated with poor prognosis in gastric carcinoma. Clin Cancer Res. 2003, 9:5693-8.
    • (2003) Clin Cancer Res. , vol.9 , pp. 5693-5698
    • Masuda, T.A.1    Inoue, H.2    Nishida, K.3
  • 71
    • 0344211819 scopus 로고    scopus 로고
    • High expression of cks1 in human non-small cell lung carcinomas
    • Inui N, Kitagawa K, Miwa S. High expression of cks1 in human non-small cell lung carcinomas. Biochem Biophys Res Commun. 2003, 303:978-84.
    • (2003) Biochem Biophys Res Commun. , vol.303 , pp. 978-984
    • Inui, N.1    Kitagawa, K.2    Miwa, S.3
  • 72
    • 17844410708 scopus 로고    scopus 로고
    • Retinoic acid stabilizes p27kip1 in EBV-immortalized lymphoblastoid B cell lines through enhanced proteasome-dependent degradation of the p45skp2 and cks1 proteins
    • Zancai P, Dal Col J, Piccinin S. Retinoic acid stabilizes p27kip1 in EBV-immortalized lymphoblastoid B cell lines through enhanced proteasome-dependent degradation of the p45skp2 and cks1 proteins. Oncogene. 2005, 24:2483-94.
    • (2005) Oncogene. , vol.24 , pp. 2483-2494
    • Zancai, P.1    Dal Col, J.2    Piccinin, S.3
  • 73
    • 33746161135 scopus 로고    scopus 로고
    • Oncostatin M induces growth arrest by inhibition of skp2, cks1, and cyclin A expression and induced p21 expression
    • Halfter H, Friedrich M, Resch A. Oncostatin M induces growth arrest by inhibition of skp2, cks1, and cyclin A expression and induced p21 expression. Cancer Res. 2006, 66:6530-9.
    • (2006) Cancer Res. , vol.66 , pp. 6530-6539
    • Halfter, H.1    Friedrich, M.2    Resch, A.3
  • 74
    • 42649135555 scopus 로고    scopus 로고
    • Fluoxetine mediates G0/G1 arrest by inducing functional inhibition of cyclin dependent kinase subunit (CKS) 1
    • Krishnan A, Hariharan R, Nair SA. Fluoxetine mediates G0/G1 arrest by inducing functional inhibition of cyclin dependent kinase subunit (CKS) 1. Biochem Pharmacol. 2008, 75:1924-34.
    • (2008) Biochem Pharmacol. , vol.75 , pp. 1924-1934
    • Krishnan, A.1    Hariharan, R.2    Nair, S.A.3
  • 75
    • 11244251791 scopus 로고    scopus 로고
    • Direct cell cycle regulation by the fibroblast growth factor receptor (FGFR) kinase through phosphorylation-dependent release of cks1 from FGFR substrate 2
    • Zhang Y, Lin Y, Bowles C. Direct cell cycle regulation by the fibroblast growth factor receptor (FGFR) kinase through phosphorylation-dependent release of cks1 from FGFR substrate 2. J Biol Chem. 2004, 279:55348-54.
    • (2004) J Biol Chem. , vol.279 , pp. 55348-55354
    • Zhang, Y.1    Lin, Y.2    Bowles, C.3
  • 76
    • 2342626681 scopus 로고    scopus 로고
    • Germline exclusion of cks1 in the mouse reveals a metaphase I role for cks proteins in male and female meiosis
    • Donovan PJ, Reed SI. Germline exclusion of cks1 in the mouse reveals a metaphase I role for cks proteins in male and female meiosis. Cell cycle. 2003, 2:275-6.
    • (2003) Cell cycle. , vol.2 , pp. 275-276
    • Donovan, P.J.1    Reed, S.I.2
  • 77
    • 11344264494 scopus 로고    scopus 로고
    • Cks1 is dispensable for survival in Saccharomyces cerevisiae
    • Yu VPCC, Reed SI. Cks1 is dispensable for survival in Saccharomyces cerevisiae. Cell cycle. 2004, 3:1402-4.
    • (2004) Cell cycle. , vol.3 , pp. 1402-1404
    • Yu, V.P.C.C.1    Reed, S.I.2
  • 78
    • 33745854417 scopus 로고    scopus 로고
    • Folding and fibril formation of the cell cycle protein cks1
    • Bader R, Seeliger MA, Kelly SE. Folding and fibril formation of the cell cycle protein cks1. J Biol Chem. 2006, 281:18816-24.
    • (2006) J Biol Chem. , vol.281 , pp. 18816-18824
    • Bader, R.1    Seeliger, M.A.2    Kelly, S.E.3
  • 79
    • 0242500260 scopus 로고    scopus 로고
    • Requirement of cks2 for the first metaphase/anaphase transition of mammalian meiosis
    • Spruck CH, de Miguel MP, Smith APL. Requirement of cks2 for the first metaphase/anaphase transition of mammalian meiosis. Science. 2003, 300:647-50.
    • (2003) Science. , vol.300 , pp. 647-650
    • Spruck, C.H.1    de Miguel, M.P.2    Smith, A.P.L.3


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