Current devices for high-performance whole-body hyperthermia therapy

Expert Review of Medical Devices

Volumn 7, Issue 3, 2010, Pages 407-423

  Jia, Dewei ^a   Liu, Jing ^a,b  

^a Tsinghua University   (China)

^b TECHNICAL INSTITUTE OF PHYSICS AND CHEMISTRY   (China)

Author keywords

Cancer therapy; Hyperthermia treatment planning; Infrared whole body hyperthermia; Interventional whole body hyperthermia; Microwave whole body hyperthermia; Whole body hyperthermia

Indexed keywords

BIOMEDICAL TECHNOLOGY ASSESSMENT; BODY TEMPERATURE; CLINICAL EFFECTIVENESS; DEVICE; ELECTROMAGNETIC FIELD; ELECTROMAGNETIC RADIATION; EXTRACORPOREAL CIRCULATION; FAR INFRARED; HEAT ACCLIMATIZATION; HEAT TRANSFER; HUMAN; HYPERTHERMIC THERAPY; IRRADIATION; MICROWAVE IRRADIATION; NEAR INFRARED IRRADIATION; NUCLEAR MAGNETIC RESONANCE IMAGING; RADIATION DOSE; RADIOFREQUENCY ABLATION; REVIEW; SAFETY; TEMPERATURE MEASUREMENT; THERMOCOUPLE; THERMOMETRY; WHOLE BODY HYPERTHERMIC THERAPY;

ABSORPTION; BODY TEMPERATURE; CONVECTION; HUMANS; HYPERTHERMIA, INDUCED; NEOPLASMS; RADIATION;

EID: 77951807918     PISSN: 17434440     EISSN: 17452422     Source Type: Journal    
DOI: 10.1586/erd.10.13     Document Type: Review

References (153)

1. Takano YS, Harmon BV, Kerr JF. Apoptosis induced by mild hyperthermia in human and murine tumour cell lines: a study using electron microscopy and DNA gel electrophoresis. J. Pathol. 163 (4), 329-336 (1991).
2. Ito A, Honda H, Kobayashi T. Cancer immunotherapy based on intracellular hyperthermia using magnetite nanoparticles: a novel concept of "heatcontrolled necrosis" with heat shock protein expression. Cancer Immunol. Immunother. 55 (3), 320-328 (2006). (Pubitemid 41682581)
3. Siddiqui F, Avery PR, Li CY et al. Induction of the human heat shock promoter HSP 70b by nutritional stress: implications for cancer gene therapy. Cancer Invest. 26 (6), 553-561 (2008). (Pubitemid 351918575)
4. Siddiqui F, Kolozsvary A, Barton KN, Freytag SO, Brown SL, Kim JH. Does hyperthermia increase adenoviral transgene expression or dissemination in tumors? Int. J. Hyperthermia 25 (4), 273-279 (2009).
5. Sugarbaker PH. Laboratory and clinical basis for hyperthermia as a component of intracavitary chemotherapy. Int. J. Hyperthermia, 23 (5), 431-442 (2007).
6. Tarner IH, Müller-Ladner U, Uhlemann C, Lange U. The effect of mild whole-body hyperthermia on systemic levels of TNF-α, IL-1β, and IL-6 in patients with ankylosing spondylitis. Clin. Rheumatol. 28 (4), 397-402 (2009).
7. Franckena M, Stalpers LJ, Koper PCM et al. Long-term improvement in treatment outcome after radiotherapy and hyperthermia in locoregionally advanced cervix cancer: an update of the Dutch Deep Hyperthermia Trial. Int. J. Radiat. Oncol. Biol. Phys. 70 (4), 1176-1182 (2008). (Pubitemid 351296102)
8. Sreedhar AS, Csermely P. Heat shock proteins in the regulation of apoptosis: new strategies in tumor therapy: a comprehensive review. Pharmacol. Ther. 101 (3), 227-257 (2004). (Pubitemid 38340861)
9. Multhoff G. Activation of natural killer cells by heat shock protein 70. Int. J. Hyperthermia 25 (3), 169-175 (2009).
10. Bergers G, Benjamin LE. Tumorigenesis and the angiogenic switch. Nat. Rev. Cancer 3 (6), 401-410 (2003). (Pubitemid 37328844)
11. Barry MA, Behnke CA, Eastman A. Activation of programmed cell death (apoptosis) by cisplatin, other anticancer drugs, toxins and hyperthermia. Biochem. Pharmacol. 40 (10), 2353-2362 (1990). (Pubitemid 20373997)
12. Hildebrandt B, Wust P, Ahlers O et al. The cellular and molecular basis of hyperthermia. Crit. Rev. Oncol. Hematol. 43 (1), 33-56 (2002). (Pubitemid 34722786)
13. Wust P, Hildebrandt B, Sreenivasa G et al. Hyperthermia in combined treatment of cancer. Lancet Oncol. 3 (8), 487-497 (2002). (Pubitemid 34863670)
14. Van der Zee J, Gonzalez D, van Rhoon GC, van Dijk JDP, van Putten WLJ, Hart AA. Comparison of radiotherapy alone with radiotherapy plus hyperthermia in locally advanced pelvic tumours: a prospective, randomised, multicentre trial. Lancet 355 (9210), 1119-1125 (2000). (Pubitemid 30172932)
15. Kraybill WG, Olenki T, Evans SS et al. A Phase I study of fever-range whole body hyperthermia (FR-WBH) in patients with advanced solid tumours: correlation with mouse models. Int. J. Hyperthermia, 18 (3), 253-266 (2002). (Pubitemid 34618582)
16. Atanackovic D, Pollok K, Faltz C et al. Patients with solid tumors treated with high-temperature whole body hyperthermia show a redistribution of naive/memory t-cell subtypes. Am. J. Physiol. Regul. Integr. Comp. Physiol. 290 (3), R585-R594 (2006).
17. Milani V, Lorenz M, Weinkauf M et al. Combination of hyperthermia and bortezomib results in additive killing in mantle cell lymphoma cells. Int. J. Hyperthermia 25 (4), 262-272 (2009).
18. Bakhshandeh A, Bruns I, Traynor A et al. Ifosfamide, carboplatin and etoposide combined with 41.8°C whole body hyperthermia for malignant pleural mesothelioma. Lung Cancer 39 (3), 339-345 (2003). (Pubitemid 36279453)
19. Wiedemann GJ, d'Oleire F, Knop E et al. Ifosfamide and carboplatin combined with 41.8°C whole-body hyperthermia in patients with refractory sarcoma and malignant teratoma. Cancer Res. 54 (20), 5346-5350 (1994). (Pubitemid 24336023)
20. Lohmann R. Pilot study of whole-body hyperthermia combined with chemotherapy in patients with metastasised pretreated progressive breast, ovarian, and colorectal carcinomas. Tumordiagn. U. Ther. 22, 115-120 (2001). (Pubitemid 34059572)
21. Park MY, Jung SE, Cho SH et al. Preliminary experience using high intensity focused ultrasound for treating liver metastasis from colon and stomach cancer. Int. J. Hyperthermia 25 (3), 180-188 (2009).
22. Strobl B, Rjosk D, Janni W et al. Whole body hyperthermia combined with carboplatin/paclitaxel in patients with ovarian carcinoma - Phase-II-study. J. Clin. Oncol. 22 (14 Suppl.), 5128-5129 (2004).
23. Atmaca A, Al-Batran SE, Neumann A et al. Whole-body hyperthermia (WBH) in combination with carboplatin in patients with recurrent ovarian cancer - a Phase II study. Gynecol. Oncol. 112 (2), 384-388 (2009).
24. Hildebrandt B, Dräger J, Kerner T et al. Whole-body hyperthermia in the scope of Von Ardenne's systemic cancer multistep therapy (sCMT) combined with chemotherapy in patients with metastatic colorectal cancer: a Phase I/II study. Int. J. Hyperthermia 20 (3), 317-333 (2004). (Pubitemid 38460997)
25. Ahmed HU, Arya M, Levitt G, Duffy PG, Sebire NJ, Mushtaq I. Part II: treatment of primary malignant non-wilms' renal tumours in children. Lancet Oncol. 8 (9), 842-848 (2007). (Pubitemid 47315502)
26. Richel O, Zum Vörde Sive Vörding PJ, Rietbroek R et al. Phase II study of carboplatin and whole body hyperthermia (WBH) in recurrent and metastatic cervical cancer. Gynecol. Oncol. 95 (3), 680-685 (2004). (Pubitemid 39592537)
27. Harima Y, Nagata K, Harima K, Ostapenko VV, Tanaka Y, Sawada S. A randomized clinical trial of radiation therapy versus thermoradiotherapy in stage IIIB cervical carcinoma. Int. J. Hyperthermia 25 (5), 338-343 (2009).
28. Bergs JW, Franken NAP, Haveman J, Geijsen ED, Crezee J, Van Bree C. Hyperthermia, cisplatin and radiation trimodality treatment: a promising cancer treatment: a review from preclinical studies to clinical application. Int. J. Hyperthermia 23 (4), 329-341 (2007). (Pubitemid 46930177)
29. Yu D-Y, Zhao Q-L, Wei Z-L, Shehata M, Kondo T. Enhancement of hyperthermiainduced apoptosis by sanazole in human lymphoma u937 cells. Int. J. Hyperthermia 25 (5), 364-373 (2009).
30. Sheeja K, Kuttan G. Effect of Andrographis paniculata as an adjuvant in combined chemo-radio and whole body hyperthermia treatment - a preliminary study. Immunopharmacol. Immunotoxicol. 30 (1), 181-194 (2008). (Pubitemid 351311970)
31. Hildebrandt B, Hegewisch-Becker S, Kerner T et al. Current status of radiant whole-body hyperthermia at temperatures >41.5°C and practical guidelines for the treatment of adults. Int. J. Hyperthermia 21 (2), 169-183 (2005).
32. Xiang S-H, Chen B-W, Zhou Y-X, Yan X-M, Liu J. Development of interventional whole body hyperthermia system: part I: device fabrication and performance evaluation. Forschung im Ingenieurwesen 72 (3), 145-152 (2008).
33. Kinsht NV, Kinsht DN. Mathematical modelling of systemic circulation and heat exchange in whole body hyperthermia (43-44 c). In: Proceeding (483) ACIT - Automation, Control, and Applications-2005. Shokin YI, Potaturkin OI (Eds). ACTA Press, Novosibirsk, Russia, 20-23 (2005).
34. Xiang S, Liu J. Comprehensive evaluation on the heating capacities of four typical whole body hyperthermia strategies via compartmental model. Int. J. Heat Mass Trans. 51 (23-24), 5486-5496 (2008).
35. Von Ardenne M, Kirsch R. On the methodology of extreme hyperthermia, with special reference to multi-step cancer chemotherapy. Dtsch. Gesundheitsw. 20 (43), 1935-1940 (1965).
36. Kirsch E, Von Ardenne M, Reitnauer PG. [A recently developed vibrating chair and its signifcance in the conservative treatment of urolithiasis. Concluding remarks]. Z. Urol. Nephrol. 58 (4), 225-236 (1965).
37. Kirsch R, Schmidt D. Klinische und experimentelle erfahrungen mit der mehrschritt-therapie. Zentralblatt für Chirurgie 36, 1297-1312 (1966).
38. Law HT, Pettigrew RT. Whole-body and regional hyperthermia by direct heating. In: Hyperthermia. Blackie, Glasgow, UK 180-201 (1986).
39. Von Ardenne M, Von Ardenne T, Böhme G, Reitnauer PG. [Selective local hyperthermy of tumor tissue. Homogenized energy supply also to deep-seated tissues by high-performance decametric wave coil section plus dual system raster motion (author transl.)]. Arch. Geschwulstforsch. 47 (6), 487-523 (1977). (Pubitemid 8238099)
40. Park WY, Macnamara TE. Temperature change and neuromuscular blockade by d-tubocurarine or pancuronium in man. Anesthesiology 50 (2), 161-163 (1979).
41. Parks LC, Minaberry D, Smith DP, Neely WA. Treatment of far-advanced bronchogenic carcinoma by extracorporeally induced systemic hyperthermia. J. Thorac. Cardiovasc. Surg. 78 (6), 883-892 (1979). (Pubitemid 10171613)
42. Maeta M, Koga S, Shimizu N et al. Effect of extracorporeally induced total body hyperthermia for cancer on cardiovascular function. Jpn. Heart J. 25 (6), 993-1000 (1984). (Pubitemid 15162063)
43. Willnow U, Lindner H, Brock D et al. [Treatment of otherwise incurable tumor diseases in childhood using whole-body hyperthermia and chemotherapy]. Dtsch. Med. Wochenschr. 114 (6), 208-213 (1989).
44. Edelmann A, Mahanna DL, Lewis LA, Thatcher JS, Hartman FA. The use of adrenal extract in fever therapy. J. Clin. Endocrinol. Metab. 3 (1), 20 (1943).
45. Robins HI, Dennis WH, Neville AJ et al. A nontoxic system for 41.8°C whole-body hyperthermia: results of a Phase I study using a radiant heat device. Cancer Res. 45 (8), 3937-3944 (1985).
46. Robins HI, Longo W. Whole body hyperthermia: simple complexities. Intensive Care Med. 25 (9), 898-900 (1999). (Pubitemid 29452532)
47. Heckel M, Heckel I. [Studies on 479 cases of infrared hyperthermia treatments. Contribution to the method of whole body hyperthermia]. Med. Welt 30 (25), 971-975 (1979). (Pubitemid 9193385)
48. Wust P, Riess H, Hildebrandt B et al. Feasibility and analysis of thermal parameters for the wholebodyhyperthermia system iratherm-2000. Int. J. Hyperthermia 16 (4), 325-339 (2000). (Pubitemid 30611729)
49. Wust P, Gneveckow U, Johannsen M et al. Magnetic nanoparticles for interstitial thermotherapy: feasibility, tolerance and achieved temperatures. Int. J. Hyperthermia 22 (8), 673-685 (2006). (Pubitemid 46332053)
50. Johannsen M, Gneveckow U, Taymoorian K et al. Morbidity and quality of life during thermotherapy using magnetic nanoparticles in locally recurrent prostate cancer: results of a prospective Phase I trial. Int. J. Hyperthermia 23 (3), 315-323 (2007). (Pubitemid 46860598)
51. Sharma R, Chen CJ. Newer nanoparticles in hyperthermia treatment and thermometry. J. Nanopart. Res. 11 (3), 671-689 (2009).
52. Foster KR, Glaser R. Thermal mechanisms of interaction of radiofrequency energy with biological systems with relevance to exposure guidelines. Health Phys. 92 (6), 609-620 (2007). (Pubitemid 46742943)
53. Nittby H, Grafstr MG, Eberhardt JL et al. Radiofrequency and extremely lowfrequency electromagnetic feld effects on the blood-brain barrier. Electromagn. Biol. Med. 27 (2), 103-126 (2008). (Pubitemid 351913222)
54. Dahl O. Status of clinical hyperthermia. Acta Oncol. 38 (7), 863-873 (1999).
55. Nikiforov V. Magnetic induction hyperthermia. Russ. Phys. J. 50 (9), 913-924 (2007).
56. Roszkowski W, Wrembel JM, Roszkowski K, Janiak M, Szmigielski S. Effect of wholebody microwave hyperthermia on delayed cutaneous hypersensitivity in tumor-bearing mice. J. Cancer Res. Clin. Oncol. 97 (1), 23-29 (1980). (Pubitemid 10100487)
57. Hauck ML, LaRue SM, Petros WP et al. Phase I trial of doxorubicin-containing low temperature sensitive liposomes in spontaneous canine tumors. Clin. Cancer Res. 12 (13), 4004-4010 (2006).
58. Nelson DA, Charbonnel S, Curran AR et al. A high-resolution voxel model for predicting local tissue temperatures in humans subjected to warm and hot environments. J. Biomech. Eng. 131, 041003 (2009).
59. Chen XL, Wang F, Bao YQ. An accidental burn resulted from whole body hyperthermia therapy. Burns 33 (2), 252-254 (2007). (Pubitemid 46201860)
60. Kokura S, Adachi S, Manabe E et al. Whole body hyperthermia improves obesity-induced insulin resistance in diabetic mice. Int. J. Hyperthermia 23 (3), 259-265 (2007). (Pubitemid 46860593)
61. Dong J, Shi-ying Z, Suo-Cheng C. Research progress of whole body hyperthermia and apoptosis of tumor cells. Medical Recapitulate 14 (1), 50-53 (2008).
62. Hager ED, Dziambor H, Hohmann D, Muhe N, Strama H. Intraperitoneal hyperthermic perfusion chemotherapy of patients with chemotherapy-resistant peritoneal disseminated ovarian cancer. Int. J. Gynecol. Cancer 11 (Suppl. 1), 57-63 (2001). (Pubitemid 32751387)
63. Douwes F, Bogovic J, Douwes O, Migeod F, Grote C. Whole-body hyperthermia in combination with platinum-containing drugs in patients with recurrent ovarian cancer. Int. J. Clin. Oncol. 9 (2), 85-91 (2004). (Pubitemid 38647165)
64. Alvarez Secord A, Jones EL, Hahn CA et al. Phase I/II trial of intravenous doxil and whole abdomen hyperthermia in patients with refractory ovarian cancer. Int. J. Hyperthermia 21 (4), 333-347 (2005).
65. Von Ardenne A, Wehner H. Extreme whole-body hyperthermia with waterfltered infrared-a radiation. In:Hyperthermia in Cancer Treatment: A Primer. Baronzio GF, Hager ED (Eds). Springer Science, NY, USA, 237 (2006).
66. Brockow T, Wagner A, Franke A, Offenbächer M, Resch KL. A randomized controlled trial on the effectiveness of mild water-fltered near infrared whole-body hyperthermia as an adjunct to a standard multimodal rehabilitation in the treatment, of fbromyalgia. Clin. J. Pain 23 (1), 67-75 (2007).
67. Kerner T, Hildebrandt B, Ahlers O et al. Anaesthesiological experiences with whole body hyperthermia. Int. J. Hyperthermia 19 (1), 1-12 (2003). (Pubitemid 36075209)
68. Schencking M, Frese T, Sandholzer H. [Treatment of a radiculopathia by whole-body hyperthermia]. sForsch Komplementmed. 15 (5), 273 (2008).
69. Yang W, Fu W, Li X et al. Clinical application of whole body hyperthermia to treat advaced carcinoma. Journal of North China Coal Medical College 6 (4), 688-690 (2002).
70. Liu Y, Ding X, Liu P, Yang Y, Pan X. Case report of whole body hyperthermia to treat bone metastasis of thyroid carcinoma. Journal of Shandong University (Health Sciences) 45 (9), 968-969 (2007).
71. Ahlers O, Hildebrandt B, Dieing A et al. Stress induced changes in lymphocyte subpopulations and associated cytokines during whole body hyperthermia of 41.8-42.2°C. Eur. J. Appl. Physiol. 95 (4), 298-306 (2005). (Pubitemid 43055091)
72. Hildebrandt B, Schoeler D, Ringel F et al. Differential gene expression in peripheral blood lymphocytes of cancer patients treated with whole body hyperthermia and chemotherapy: a pilot study. Int. J. Hyperthermia 22 (8), 625-635 (2006). (Pubitemid 46332050)
73. Wehner H, Von Ardenne A, Kaltofen S. Whole-body hyperthermia with water-. fltered infrared radiation: technicalphysical aspects and clinical experiences. Int. J. Hyperthermia 17 (1), 19-30 (2001). (Pubitemid 32058479)
74. Ohishi T, Nukuzuma C, Seki A et al. Alkalization of blood ph is responsible for survival of cancer patients by mild hyperthermia. Biomed. Res. 30 (2), 95 (2009).
75. Bull JMC, Scott GL, Strebel FR et al. Fever-range whole-body thermal therapy combined with cisplatin, gemcitabine, and daily interferon-a: a description of a Phase I-II protocol. Int. J. Hyperthermia 24 (8), 649-662 (2008).
76. Wrzal PK, Bettaieb A, Averill-Bates DA. Molecular mechanisms of apoptosis activation by heat shock in multidrugresistant chinese hamster cells. Radiat. Res. 170 (4), 498-511 (2008).
77. Sumiyoshi K, Strebel FR, Rowe RW, Bull JMC. The effect of whole-body hyperthermia combined with 'metronomic' chemotherapy on rat mammary adenocarcinoma metastases. Int. J. Hyperthermia 19 (2), 103-118 (2003). (Pubitemid 36304680)
78. Pritchard MT, Ostberg JR, Evans SS et al. Protocols for simulating the thermal component of fever: preclinical and clinical experience. Methods 32 (1), 54-62 (2004).
79. Pritchard MT, Wolf SF, Kraybill WF, Repasky EA. The anti-tumor effect of interleukin-12 is enhanced by mild (fever-range) thermal therapy. Immunol. Invest. 34 (3), 361-380 (2005).
80. Ishibashi J, Yamashita K, Ishikawa T et al. The effects inhibiting the proliferation of cancer cells by far-infrared radiation (FIR) are controlled by the basal expression level of heat shock protein (HSP) 70a. Med. Oncol. 25 (2), 229-237 (2008).
81. Hattori T, Kokura S, Okuda T et al. Antitumor effect of whole body hyperthermia with α-galactosylceramide in a subcutaneous tumor model of colon cancer. Int. J. Hyperthermia 23 (7), 591-598 (2007). (Pubitemid 350187054)
82. Toyokawa H, Matsui Y, Uhara J et al. Promotive effects of far-infrared ray on full-thickness skin wound healing in rats. Exp. Biol. Med. (Maywood) 228 (6), 724-729 (2003). (Pubitemid 37163264)
83. Yamada Y, Itoh Y, Aoki S et al. Preliminary results of m-vac chemotherapy combined with mild hyperthermia, a new therapeutic strategy for advanced or metastatic transitional cell carcinoma of the urothelium. Cancer Chemother. Pharmacol. 64 (6), 1079-1083 (2009).
84. Witkamp AJ, De Bree E, Kaag MM et al. Extensive cytoreductive surgery followed by intra-operative hyperthermic intraperitoneal chemotherapy with mitomycin-c in patients with peritoneal carcinomatosis of colorectal origin. Eur. J. Cancer 37 (8), 979-984 (2001). (Pubitemid 32397682)
85. Witkamp AJ, de Bree E, Van Goethem R, Zoetmulder FA. Rationale and techniques of intra-operative hyperthermic intraperitoneal chemotherapy. Cancer Treat. Rev. 27 (6), 365-374 (2001). (Pubitemid 34413980)
86. Witkamp AJ, De Bree E, Kaag MM, Van Slooten GW, Van Coevorden F, Zoetmulder FA. Extensive surgical cytoreduction and intraoperative hyperthermic intraperitoneal chemotherapy in patients with pseudomyxoma peritonei. Br. J. Surg. 88 (3), 458-463 (2001). (Pubitemid 32238713)
87. Matsuzaki Y, Edagawa M, Shimizu T et al. Intrapleural hyperthermic perfusion with chemotherapy increases apoptosis in malignant pleuritis. Ann. Thorac. Surg. 78 (5), 1769-1772 (2004). (Pubitemid 39423551)
88. Zwischenberger JB, Vertrees RA, Woodson LC et al. Percutaneous venovenous perfusion-induced systemic hyperthermia for advanced non-small cell lung cancer: initial clinical experience. Ann. Thorac. Surg. 72 (1), 234-242 (2001). (Pubitemid 32643044)
89. Vertrees RA, Leeth A, Girouard M, Roach JD, Zwischenberger JB. Whole-body hyperthermia: a review of theory, design and application. Perfusion 17 (4), 279-290 (2002). (Pubitemid 34830953)
90. Zwischenberger JB, Vertrees RA, Bedell EA, McQuitty CK, Chernin JM, Woodson LC. Percutaneous venovenous perfusion-induced systemic hyperthermia for lung cancer: a Phase I safety study. Ann. Thorac. Surg. 77 (6), 1916-1925 (2004).
91. Vertrees RA, Das GC, Coscio AM, Xie J, Zwischenberger JB, Boor PJ. A mechanism of hyperthermia-induced apoptosis in ras-transformed lung cells. Mol. Carcinog. 44 (2), 111-121 (2005). (Pubitemid 41397175)
92. Vertrees RA, Das GC, Popov VL et al. Synergistic interaction of hyperthermia and gemcitabine in lung cancer. Cancer Biol. Ther. 4 (10), 1144-1153 (2005). (Pubitemid 41598572)
93. Bernard AC, Davenport DL, Chang PK, Vaughan TB, Zwischenberger JB. Intraoperative transfusion of 1 U to 2 U packed red blood cells is associated with increased 30-day mortality, surgical-site infection, pneumonia, and sepsis in general surgery patients. J. Am. Coll. Surg. 208 (5), 931-937 (2009).
94. Xiang S-H, Chen B-W, He X-H et al. Development of interventional whole body hyperthermia system: part II: in vivo animal experimental evaluation. Forschung im Ingenieurwesen 73 (3), 139-146 (2009).
95. Xiang S-H, Liu J, Zhou Y-X, Yan X-M. Monitoring temperature of a heating needle and surrounding blood during interventional whole body hyperthermia therapy. Meas. Sci. Tech. 18 (11), 3417-3424 (2007). (Pubitemid 350132693)
96. Malyutina YV, Makarova YM, Semenets TN, Semina OV, Mosin AF, Kabakov AE. Whole body hyperthermia in mice confers heat shock protein-dependent radioresistance of their bone marrow and thymocytes. J. Therm. Biol. 30 (7), 511-517 (2005).
97. Tolson JK, Roberts SM. Manipulating heat shock protein expression in laboratory animals. Methods 35 (2), 149-157 (2005). (Pubitemid 40092640)
98. Chankova SG, Yurina NP, Dimova EG et al. Pretreatment with heat does not affect double-strand breaks DNA rejoining in Chlamydomonas reinhardtii. J. Therm. Biol. 34 (7), 332-336 (2009).
99. Zaidi AK, Patil MS, Bagewadikar RS, Subramanian M, Kaklij GS. Radioprotection by whole body hyperthermia: possible mechanism (s). J. Therm. Biol. 27 (1), 29-37 (2002). (Pubitemid 34063315)
100. Blatteis CM. Endotoxic fever: new concepts of its regulation suggest new approaches to its management. Pharmacol. Ther. 111 (1), 194-223 (2006).
101. Nyberg F, Hallberg M, Hari Shanker S. Neuropeptides in hyperthermia. In: Progress in Brain Research. Elsevier, MO, USA, 277-293 (2007). (Pubitemid 47080951)
102. Vinkers CH, Van Bogaert MJ, Klanker M et al. Translational aspects of pharmacological research into anxiety disorders: the stress-induced hyperthermia (sih) paradigm. Eur. J. Pharmacol. 585 (2-3), 407-425 (2008).
103. Szelényi Z. Cholecystokinin: role in thermoregulation and other aspects of energetics. Clin. Chim. Acta 411 (5-6), 329-335 (2009).
104. Dhiraj A, Daniel C, Trent P, Mikhail S, Robert BR. Direct thermal dose control of constrained focused ultrasound treatments: phantom and in vivo evaluation. Phys. Med. Biol. 50 (8), 1919-1935 (2005). (Pubitemid 41223657)
105. Arora D, Skliar M, Cooley D, Blankespoor A, Moellmer J, Roemer R. Nonlinear model predictive thermal dose control of thermal therapies: experimental validation with phantoms. In: American Control Conference, 2004. Proceedings of the 2004 American Control Conference. AAC (Eds). IEEE, Boston, MA, USA, 1627-1632 (2004).
106. Hjertaker BT, Froystein T, Schem BC. A thermometry system for quality assurance and documentation of whole body hyperthermia procedures. Int. J. Hyperthermia 21 (1), 45-55 (2005).
107. Wust P, Cho CH, Hildebrandt B, Gellermann J. Thermal monitoring: invasive, minimal-invasive and noninvasive approaches. Int. J. Hyperthermia 22 (3), 255-262 (2006). (Pubitemid 43878687)
108. Sikoski P, Banks ML, Gould R, Young RW, Wallace JM, Nader MA. Comparison of rectal and infrared thermometry for obtaining body temperature in cynomolgus macaques (Macaca fascicularis). J. Med. Primatol. 36 (6), 381-384 (2007). (Pubitemid 350042176)
109. Kistemaker JA, Den Hartog EA, Daanen HA. Reliability of an infrared forehead skin thermometer for core temperature measurements. J. Med. Eng. Technol. 30 (4), 252-261 (2006). (Pubitemid 44177380)
110. Zhang S, Malloy CR, Sherry AD. MRI thermometry based on paracest agents. J. Am. Chem. Soc. 127 (50), 17572 (2005). (Pubitemid 43003350)
111. Vanne A, Hynynen K. MRI feedback temperature control for focused ultrasound surgery. Phys. Med. Biol. 48 (1), 31-43 (2003). (Pubitemid 36124062)
112. Wyatt C, Soher B, Maccarini P, Charles HC, Stauffer P, Macfall J. Hyperthermia mri temperature measurement: evaluation of measurement stabilisation strategies for extremity and breast tumours. Int. J. Hyperthermia 25 (6), 422-433 (2009).
113. Mirko W, Peter W, Martin W et al. Adaptation of antenna profles for control of mr guided hyperthermia (HR) in a hybrid MR-HT system. Med. Phys. 34 (12), 4717-4725 (2007).
114. Bayford RH. Bioimpedance tomography (electrical impedance tomography). Annu. Rev. Biomed. Eng. 8 (1), 63-91 (2006).
115. Meaney PM, Paulsen KD, Fanning MW, Li D, Fang Q. Image accuracy improvements in microwave tomographic thermometry: phantom experience. Int. J. Hyperthermia 19 (5), 534-550 (2003). (Pubitemid 37138730)
116. Xia Y, Hu Z, Nan Q, Jia L, Peng J, Zeng Y. Design of double ultrasound pulse transmission and receiving circuit used in ultrasound thermometry. J. Med. Eng. Tech. 30 (2), 112-118 (2006).
117. Kamiyama T, Ito J, Noda H, Iwasa H, Kiyanagi Y, Ikeda S. Computer tomography thermometry - an application of neutron resonance absorption spectroscopy. Nucl. Instrum. Meth. Phys. Res. A 542 (1-3), 258-263 (2005). (Pubitemid 40556867)
118. Han B, Hanson W, Bensalah K, Tuncel A, Stern J, Cadeddu J. Development of quantum dot-mediated fuorescence thermometry for thermal therapies. Ann. Biomed. Eng. 37 (6), 1230-1239 (2009).
119. Szasz A, Szasz O, Szasz N. Electrohyperthermia: a new paradigm in cancer therapy. DZO 33 (3), 91-99 (2001). (Pubitemid 38173273)
120. Fiorentini G, Szasz A. Hyperthermia today: electric energy, a new opportunity in cancer treatment. J. Cancer Res. Ther. 2 (2), 41-46 (2006). (Pubitemid 43926439)
121. Andocs G, Szasz O, Szasz A. Oncothermia treatment of cancer: from the laboratory to clinic. Electromagn. Biol. Med. 28 (2), 148-165 (2009).
122. Andocs G, Renner H, Balogh L, Fonyad L, Jakab C, Szasz A. Strong synergy of heat and modulated electromagnetic feld in tumor cell killing. Strahlenther. Onkol. 185 (2), 120-126 (2009).
123. Kennedy JE. Innovation: high-intensity focused ultrasound in the treatment of solid tumours. sNat. Rev. Cancer 5 (4), 321-327 (2005). (Pubitemid 40488637)
124. Wootton JH, Ross AB, Diederich CJ. Prostate thermal therapy with high intensity transurethral ultrasound: the impact of pelvic bone heating on treatment delivery. Int. J. Hyperthermia 23 (8), 609-622 (2007).
125. Burtnyk M, Chopra R, Bronskill MJ. Quantitative analysis of 3-D conformal MRI-guided transurethral ultrasound therapy of the prostate: theoretical simulations. Int. J. Hyperthermia 25 (2), 116-131 (2009).
126. Puccini S, Bar NK, Bublat M, Kahn T, Busse H. Simulations of thermal tissue coagulation and their value for the planning and monitoring of laser-induced interstitial thermotherapy (LITT). Magn. Res. Med. 49 (2), 351-362 (2003). (Pubitemid 36159873)
127. Vesselov LM, Whittington W, Lilge L. Performance evaluation of cylindrical fber optic light diffusers for biomedical applications. Lasers Surg. Med. 34 (4), 348-351 (2004). (Pubitemid 38496137)
128. Ma N, Gao X, Zhang XX. Two-layer simulation model of laser-induced interstitial thermo-therapy. Lasers Med. Sci. 18 (4), 184-189 (2004). (Pubitemid 38660652)
129. Zhou J, Liu J. Numerical study on 3-D light and heat transport in biological tissues embedded with large blood vessels during laser-induced thermotherapy. Numerical Heat Transfer: Part A - Applications, 45 (5), 415-449 (2004).
130. Zhou J, Zhang Y, Chen J. Effects of large blood vessels on the transient propagation of ultrafast laser pulse in biological tissues. Heat Mass Trans. 45 (5), 527-535 (2009). (Pubitemid 46853993)
131. 3 nanoparticles: the effect of temperature autostabilization. Int. J. Hyperthermia 25 (3), 240-247 (2009).
132. Li F-R, Yan W-H, Guo Y-H, Qi H, Zhou H-X. Preparation of carboplatin-fecloaded chitosan nanoparticles and study on hyperthermia combined with pharmacotherapy for liver cancer. Int. J. Hyperthermia 25 (5), 383-391 (2009).
133. Renard P-EL, Buchegger F, Petri-Fink A et al. Local moderate magnetically induced hyperthermia using an implant formed in situ in a mouse tumor model. Int. J. Hyperthermia 25 (3), 229-239 (2009).
134. Salloum M, Ma R, Zhu L. Enhancement in treatment planning for magnetic nanoparticle hyperthermia: optimization of the heat absorption pattern. Int. J. Hyperthermia 25 (4), 309-321 (2009).
135. Babincova M, Sourivong P, Leszczynska D, Babinec P. Blood-specifc whole-body electromagnetic hyperthermia. Med. Hypotheses 55 (6), 459-460 (2000).
136. Babincova M, Altanerova V, Altaner C, Cicmanec P, Babinec P. In vivo heating of magnetic nanoparticles in alternating magnetic feld. Med. Phys. 31 (8), 2219-2221 (2004). (Pubitemid 39079713)
137. Sreenivasa G, Gellermann J, Rau B et al. Clinical use of the hyperthermia treatment planning system hyperplan to predict effectiveness and toxicity. Int. J. Radiat. Oncol. Biol. Phys. 55 (2), 407-419 (2003). (Pubitemid 36069099)
138. Bakshandeh A, Bruns I, Eberhardt K et al. Ifosfamide, carboplatin and etoposide combined with aquatherm-induced 41.8 °C whole-body hyperthermia for adult patients with malignant pleural mesothelioma. Ann. Oncol. 11 (4), 113-115 (2000).
139. Westermann AM, Wiedemann GJ, Jager E et al. A systemic hyperthermia oncologic working group trial. Ifosfamide, carboplatin, and etoposide combined with 41.8°C whole-body hyperthermia for metastatic soft tissue sarcoma. Oncology 64 (4), 312-321 (2003). (Pubitemid 36682942)
140. Dieing A, Ahlers O, Kerner T et al. Whole body hyperthermia induces apoptosis in subpopulations of blood lymphocytes. Immunobiology 207 (4), 265-273 (2003). (Pubitemid 37009922)
141. Gong B, Asimakis GK, Chen Z et al. Whole-body hyperthermia induces up-regulation of vascular endothelial growth factor accompanied by neovascularization in cardiac tissue. Life Sci. 79 (19), 1781-1788 (2006). (Pubitemid 44441449)
142. Chen M-Y, Lin J-H, Tai D-Y et al. Alteration of arterial blood pressure and myocardial injury induced by whole body hyperthermia in pigs. J. Mol. Cell. Cardiol. 40 (6), 1009 (2006).
143. Lagendijk JJW. Hyperthermia treatment planning. Phys. Med. Biol. (5), R61 (2000).
144. Gellermann J, Wust P, Stalling D et al. Clinical evaluation and verifcation of the hyperthermia treatment planning system hyperplan. Int. J. Radiat. Oncol. Biol. Phys. 47 (4), 1145-1156 (2000). Websites (Pubitemid 30345616)
145. Extracorporeal Heating System Blood Temperature Control System www.cszmedical.com/products/extracorporeal/ecmoheater.htm
146. PWH-A microwave whole-body hyperthermia device www.tsinghuatf.com.cn/ product.asp?p-id=14
147. Far-infrared system: HM-7752 Rolling Bed www.tradekorea.com/product- detail/P00013214/Rolling-bed-HM-7752-. html
148. Hyperthermia treatment therapy www.electricalbody.us/
149. Hyper-Hypothermia Systems Whole Body Hyperthermia Systems from CSZ www.cszmedical.com/products/hyperhypthermia/Blanketrol3.htm
150. ET-space infrared whole-body hyperthermia device www.eti.com.cn
151. von Ardenne's Institute for Applied Medicine Research www.ardenne.de/med
152. Heckel Hyperthermie www.heckel-medizintechnik.de
153. OncoTherm www.oncotherm.org