Lyso-glycosphingolipids mobilize calcium from brain microsomes via multiple mechanisms

Biochemical Journal

Volumn 375, Issue 3, 2003, Pages 561-565

  Lloyd Evans, Emyr ^a,b   Pelled, Dori ^a   Riebeling, Christian ^a   Futerman, Anthony H ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Galactosylsphingosine; Glucosylsphingosine; Ins(1,4, 5)P3; Lactosylsphingosine; Ryanodine; Thapsigargin

Indexed keywords

BRAIN; CELLS; CYTOLOGY; GLUCOSE; LIPIDS;

ENDOPLASMIC RETICULUM; MICROSOMES;

BIOCHEMISTRY;

ADENOSINE TRIPHOSPHATASE (CALCIUM); CALCIUM; GLYCOSPHINGOLIPID; HEPARIN; RYANODINE RECEPTOR; THAPSIGARGIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN; CALCIUM TRANSPORT; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; MICROSOME; NONHUMAN; PRIORITY JOURNAL; RAT; SARCOPLASMIC RETICULUM; SENSITIZATION;

ANIMALS; BRAIN; CALCIUM; CALCIUM-TRANSPORTING ATPASES; GLYCOSPHINGOLIPIDS; INOSITOL PHOSPHATES; MICROSOMES; MODELS, BIOLOGICAL; PSYCHOSINE; RATS; RATS, WISTAR; RYANODINE; SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES; SPHINGOSINE; THAPSIGARGIN;

ANIMALIA;

EID: 0242637088     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20030613     Document Type: Article

References (32)

1. Buccoliero, R., Bodennec, J. and Futerman, A. H. (2002) The role of sphingolipids in neuronal development: lessons from models of sphingolipid storage diseases. Neurochem. Res. 27, 565-574
2. 2+ mobilization by sphingosylphosphorylcholine and galactosylsphingosine in HL60 leukemia cells. Implications of GTP-binding protein-coupled receptors for lysosphingolipids. J. Biol. Chem. 270, 26332-26340
3. Liu, R., Farach-Carson, M. C. and Karin, N. J. (1995) Effects of sphingosine derivatives on MC3T3-E1 pre-osteoblasts: psychosine elicits release of calcium from intracellular stores. Biochem. Biophys. Res. Commun. 214, 676-684
4. 2+ current by lysosphingolipids in RINm5F insulinoma cells. Mol. Pharmacol. 53, 862-869
5. Igisu, H., Hamasaki, N., Ito, A. and Ou, W. (1988) Inhibition of cytochrome c oxidase and hemolysis caused by lysosphingolipids. Lipids 23, 345-348
6. Sohal, P. S. and Cornell, R. B. (1990) Sphingosine inhibits the activity of rat liver CTP:phosphocholine cytidylyltransferase. J. Biol. Chem. 265, 11746-11750
7. Hannun, Y. A. and Bell, R. M. (1987) Lysosphingolipids inhibit protein kinase C: implications for the sphingolipidoses. Science 235, 670-674
8. Hannun, Y. A. and Bell, R. M. (1989) Functions of sphingolipids and sphingolipid breakdown products in cellular regulation. Science 243, 500-507
9. Ariga, T., Jarvis, W. D. and Yu, R. K. (1998) Role of sphingolipid-mediated cell death in neurodegenerative diseases. J. Lipid Res. 39, 1-16
10. Wegner, D. A., Suzuki, K., Suzuki, Y. and Suzuki, K. (2001) Galactosylceramide lipidosis: globoid cell leukodystrophy (Krabbe disease). In The Metabolic and Molecular Bases of Inherited Disease, vol. 2 (Scriver, C. R., Sly, W. S., Childs, B., Beaudet, A. L., Valle, D., Kinzler, K. W. and Vogelstein, B., eds.), pp. 3669-3694, McGraw-Hill, New York
11. Beutler, E. and Grabowski, G. A. (2001) Gaucher disease. In The Metabolic and Molecular Bases of Inherited Disease, vol. 2 (Scriver, C. R., Sly, W. S., Childs, B., Beaudet, A. L., Valle, D., Kinzler, K. W. and Vogelstein, B., eds.), pp. 3635-3668, McGraw-Hill, New York
12. Suzuki, K. (1998) Twenty five years of the 'psychosine hypothesis': a personal perspective of its history and present status. Neurochem. Res. 23, 251-259
13. Korkotian, E., Schwarz, A., Pelled, D., Schwarzmann, G., Segal, M. and Futerman, A. H. (1999) Elevation of intracellular glucosylceramide levels results in an increase in endoplasmic reticulum density and in functional calcium stores in cultured neurons. J. Biol. Chem. 274, 21673-21678
14. Lloyd-Evans, E., Pelled, D., Riebeling, C., Bodennec, J., de-Morgan, A., Waller, H., Schiffmann, R. and Futerman, A. H. (2003) Glucosylceramide and glucosylsphingosine modulate calcium mobilization from brain microsomes via different mechanisms. J. Biol. Chem. 278, 23594-23599
15. Pelled, D., Shogomori, H. and Futerman, A. H. (2000) The increased sensitivity of neurons with elevated glucocerebroside to neurotoxic agents can be reversed by imiglucerase. J. Inherit. Metab. Dis, 23, 175-184
16. Nowycky, M. C. and Thomas, A. P. (2002) Intracellular calcium signaling. J. Cell Sci. 115, 3715-3716
17. Betto, R., Teresi, A., Turcato, F., Salviati, G., Sabbadini, R. A., Krown, K., Glembotski, C. C., Kindman, L. A., Dettbarn, C., Pereon, Y. et al. (1997) Sphingosylphosphocholine modulates the ryanodine receptor/ calcium-release channel of cardiac sarcoplasmic reticulum membranes. Biochem. J. 322, 327-333
18. Bradford, M. M. (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72, 248-254
19. 2+ release by organic polyamines. J. Biol. Chem. 262, 6149-6154
20. Dettbarn, C., Betto, R., Salviati, G., Sabbadini, R. and Palade, P. (1995) Involvement of ryanodine receptors in sphingosylphosphorylcholine- induced calcium release from brain microsomes. Brain Res. 669, 79-85
21. 2+ ATPase enzymatic properties using mouse cardiac tissue homogenates. Anal. Biochem. 269, 236-244
22. 2+-permeable pore of the calcium release channel. J. Biol. Chem. 262, 16636-16643
23. Fabiato, A. and Fabiato, F. (1979) Calculator programs for computing the composition of the solutions containing multiple metals and ligands used for experiments in skinned muscle cells. J. Physiol. (Paris) 75, 463-505
24. 2+ protects against thapsigargin inhibition in neuronal endoplasmic reticulum. J. Biol. Chem. 273, 5020-5025
25. Ghosh, T. K., Bian, J. H. and Gill, D. L. (1994) Sphingosine 1-phosphate generated in the endoplasmic reticulum membrane activates release of stored calcium. J. Biol. Chem. 269, 22628-22635
26. 2+ signaling. Curr. Opin. Neurobiol. 7, 339-345
27. 2+-ATPases. Trends Pharmacol. Sci. 19, 131-135
28. 2+]. Biochim. Biophys. Acta 1509, 42-54
29. Bodennec, J., Pelled, D., Riebeling, C., Trajkovic, S. and Futerman, A. H. (2002) Phosphatidylcholine synthesis is elevated in neuronal models of Gaucher disease due to direct activation of CTP:phosphocholine cytidylyltransferase by glucosylceramide. FASEB J. 16, 1814-1816
30. 3H]aceric anhydride. J. Lipid. Res. 44, 1413-1419
31. Tybulewicz, V. L. J., Tremblay, M. L., LaMrca, M. E., Willemsen, R., Stubblefield, B. K., Winfield, S., Zablocka, B., Sidransky, E., Martin, B. M., Huang, S. P. et al. (1992) Animal model of Gaucher's disease from targeted disruption of the mouse glucocerebrasidase gene. Nature (London) 357, 407-410
32. Nilsson, O. and Svennerholm, L. (1982) Accumulation of glucosylceramide and glucosylsphingosine (psychosine) in cerebrum and cerebellum in infantile and juvenile Gaucher disease. J. Neurochem. 39, 709-718